Zanamivir resources


DRUG INFO
Zanamivir

Drug Name: Zanamivir

Indication: For the prevention and treatment of influenza



Pharmacology: Zanamivir, an antiviral agent, is a neuraminidase inhibitor indicated for treatment of uncomplicated acute illness due to influenza A and B virus in adults and pediatric patients 7 years and older who have been symptomatic for no more than 2 days.

Mechanism Of Action: The proposed mechanism of action of zanamivir is via inhibition of influenza virus neuraminidase with the possibility of alteration of virus particle aggregation and release.

Drug Category: Antivirals; Enzyme Inhibitors; Neuraminidase Inhibitors; ATC:J05AH01

Brand Names/Synonyms: GANA; GG 167; GNA; MODIFIED SIALIC ACID; Relenza; See Remark 8; ZMR; Zanamavir; Zanamivir

Dosage Forms: POWDER

Absorption: 4% to 17% following an orally inhaled dose

Interactions: DrugBank: Interactions for Zanamivir

Interactions for Zanamivir:


No clinically significant pharmacokinetic drug interactions are predicted based on data from in vitro studies.





Chemical IUPAC Name: 5-acetamido-4-guanidino-6-(1,2,3-trihydroxypropyl)-5,6-dihydro-4H-pyran-2-carboxylic acid

Chemical Formula: C12H20N4O7

Half Life: 2.5-5.1 hours

Drug Type: Approved Drug

# Accession No: APRD00378

CAS Registry Number: 139110-80-8



Zanamivir News
(When available)


Threats Of Attacks Put Fear In Residents Of Bimbilla  16 Jan 2006
Ghana News Today - Citi FM, Mammy trucks from the southern parts of the country were seen loading yams in almost every community the GNA visited within the district. ...

Papa Dako transported in the cloud of glory ... from Abiriw  16 Jan 2006
Ghanaian Chronicle, By GNA | Posted: Monday, January 16, 2006. Abiriw-Akuapem witnessed the funeral ceremonies, interment and eventual shedding of the ...

GMMB director wants bylaws enforced around castles  16 Jan 2006
Accra Daily Mail, Briefing the GNA on the number of visitors to the castles and revenue accruing, he said 45,876 tourists visited the Cape Coast castle last year against 36,845 ...

Avoiding inheritance confusion - Ato Essuman tasks royal families  16 Jan 2006
Accra Daily Mail, Area and held discussions with Nana Kwamina Ansah IV, President of the Regional House of Chiefs and Omanhene of the Eguafo Traditional Area at Eguafo. GNA.

Gerdau Ameristeel Announces Leadership Changes  Jan 13, 2006
PR Newswire (press release), TAMPA, FL, Jan. 13 /PRNewswire-FirstCall/ - Gerdau Ameristeel Corporation (NYSE: GNA; TSX: GNA.TO) today announced the following leadership changes. ...

Prisoners show off what they can do  Jan 13, 2006
Accra Daily Mail, Briefing the GNA on the essence of the exhibition Mrs. Josephine Fredua-Agyemang, Chief Superintendent of Prisons in-charge of the female wng of the prison ...

CAF trio okays preliminary works  Jan 8, 2006
Nigeria Daily Independent, Jean Marie Weber, Marketing Advisor to the Federation, told the GNA Sports: "we are satisfied with the spate of work and highly pleased with government's ...

My silence is deliberate - Mills  Jan 13, 2006
Ghanaian Chronicle, By GNA | Posted: Friday, January 13, 2006. Professor John Evans Atta Mills, Former Vice ... the New Patriotic Party, was also present. - GNA.

JAK charges GNAT ... to sanction wayward teachers  Jan 10, 2006
Ghanaian Chronicle, ...by GNA | Posted: Tuesday, January 10, 2006. President John Agyekum Kufuor has called ... and with some capacity for initiative. - GNA.

TUC boss slams gov't for paying low wages … says congress to ...  Jan 9, 2006
Ghanaian Chronicle, ...by GNA | Posted: Monday, January 09, 2006. ... Mr Thomas Ango Bediako, Chairman of the Presidential Commission on Pensions, chaired the symposium. - GNA.

‘Night Soil’ carriers haul AMA, AG to court  Jan 9, 2006
Ghanaian Chronicle, ...by GNA | Posted: Monday, January 09, 2006. Nana Adjei Ampofo, an Accra-based lawyer ... defends legal suits against government," he said. - GNA.

Otumfuo’s cool bursts can't tolerate school land calls on Lands ...  Jan 9, 2006
Ghanaian Chronicle, ...by GNA | Posted: Monday, January 09, 2006. Otumfuo Osei Tutu II, the Asantehene, has ... boreholes to give them good drinking water". - GNA.

GHANA: Explosion at Cadbury injures workers  Jan 6, 2006
African News Dimension, When the GNA arrived at the scene, a fire van had parked within the premises of the company with a number of firemen hovering around the scene whilst a number ...

Boniface wins confidence of Tamalians!  Jan 11, 2006
Accra Daily Mail, Speaking to the GNA in separate interviews in Tamale on Tuesday, Mr. Albert Atutiga, Regional Chairman of the Convention People's Party (CPP) said, "The ...

GCB Adopts Measures to Give Customers Better ATm Service  Dec 19, 2005
TMCnet Responding to questions regarding recent complaints by some ATM users of the Bank, Mr Roko Frimpong, Deputy Managing Director of the GCB, told the GNA that the ...

ECOWAS Leaders To Meet Next Week  Jan 6, 2006
Ghana News Today - Citi FM, ...summit would also elect a Chairman for the regional grouping, Dr Adrienne Diop, head of the ECOWAS Communication Department, told the Ghana News Agency (GNA). ...

Okine To Fight Ugandan In CBC Eliminator  Jan 11, 2006
Daily Graphic, Speaking to the GNA Sports, Okine vowed to make amends this time around, adding that he has trained and prepared adequately for the fight. ...

Chief Attacked Over Land Dispute  Jan 2, 2006
Daily Graphic, Deputy Superintendent of Police (DSP) BB Bakomora, the Swedru District Police Commander, who disclosed this to the Ghana News Agency (GNA) at Agona Swedru on ...

DDA made several crucial decisions for its growth  Dec 28, 2005
Romeo Observer, MT, ...internally and publicly. In early March, the DDA declined to renew its contract with the Utica-based GNA Marketing Group. The firm ...

Mining revenue expected to go up despite declines in third quarter  Dec 22, 2005
Joy Online, According to statistics from the Chamber of Mines made available the Ghana News Agency (GNA) gold production in the third quarter was at 4.87 per cent compared ...

Sylvester Dennis wins Muscle Mania West Africa2005 Contest  Dec 18, 2005
Ghana News Today - Citi FM, Sabato, in a subsequent interview with GNA Sports said that the results was a heart breaking one for him after having suspended all conjugal rights for the ...

Ghana Places 76 in Economic Freedom Survey  Jan 9, 2006
TMCnet ...production required property rights and free decisions by market participants that were difficult or impossible to coordinate to the victor's advantage. GNA.

Pump, pageantry and bloody clash at NPP Congress  Dec 18, 2005
News in Ghana, Mr Ishmael Abbey, Leader of Peace Spinners, told the GNA that he stepped away from the spinning spot for a few minutes only to return to see members of his ...

Dual core Yonah previewed again  Dec 28, 2005
Inquirer, Loads of details and images and sixteen pages of pure rodent pleasure. Gna, Gna. Anyone from E7even or using E7even, please contact me. ...

LCBCs complain of shortage of jute sacks  Jan 5, 2006
Joy Online, District Officers of the companies disclosed this to the Ghana News Agency (GNA) during visits to some cocoa buying centres in the two districts on Monday. ...

Gov’t Urged To Be Committed To Agricultural Deve’t  Jan 3, 2006
Ghana News Today - Citi FM, ...development. Osofo Patrick Adingtinga Apullah, General Secretary of APFOG made the call in an interview with the GNA at Nyankpala. ...

Two Arrested For Fraud  Jan 2, 2006
Daily Graphic, Mr Nicholas Gasu, Winneba District Police Commander, told the GNA that in 2003, Mr Obeng, a former Koforidua District Manager of the Federated Commodities ...

Ghana: Wee smoking on the rise  Jan 6, 2006
African News Dimension, ..."The Psychiatric Observation Department is usually filled with the youth, mostly JSS and SSS students,'' he told the GNA in an interview on Friday. ...

Air Safety Must Be Paramount — Mangera  Jan 5, 2006
Daily Graphic, Speaking to the Ghana News Agency (GNA) Business Desk in Accra, on airline safety, Mr Mangera was optimistic that airlines within the sub-region had the ...

LOCAL BRIEFS  Jan 5, 2006
Wilkes Barre Times-Leader, NANTICOKE – The Greater Nanticoke Area School District will be hosting a district orchestra at 2 pm Saturday in the GNA High School auditorium. ...

Govts delay meeting to discuss gas export prices to Jan  Jan 6, 2006
BNamericas, The meeting was also expected to address the proposed US$1bn Gasoducto del Nordeste Argentina (GNA) pipeline that would ship 20Mm3/d of gas initially from ...

Ghana tracked among preferred countries for offshore services  Jan 5, 2006
Africast, Besancon of the Policy Division of the Global ICT Department of the World Bank acknowledging the nation's performance and forwarded to the GNA said "...Ghana ...

CPP ACTIVIST CONGRATULATES MAC MANU ON VICTORY --- SAYS IT IS ...  Dec 19, 2005
Kessben FM, President, Osagyefo Dr. Kwame Nkrumah publicly endorsed Mr. Mac Manu before the NPP Congress through Kessben Fm in Kumasi, Ghana News Agency (GNA) offices in ...

Minimill to expand, add 30 jobs  Dec 19, 2005
Charlotte Business Journal, ...excluding benefits. Tampa, Fla.-based Gerdau (NYSE:GNA) touts itself as the fourth-largest steel manufacturer in the United States. The ...

GFA Puts World Cup Tickets Up For Sale  Dec 29, 2005
Ghana News Today - Citi FM, Mr Kofi Nsiah, General Secretary of the GFA in a Press Statement copied to the GNA Sports said all successful applicants would be contacted in due time and ...

Gold production dips yet Gold Fields shines  Dec 22, 2005
News in Ghana, A statement made available to the Ghana News Agency (GNA) Business Desk on Wednesday only mentioned a marginal output of 0.19 per cent in diamond production ...

Bagbin, Kyei-Mensah impressed with Speaker  Dec 15, 2005
News in Ghana, Mr. Kyei-Mensah-Bonsu said this in an interview with the Ghana News Agency (GNA) on the performance of Parliament in the First Session of the Fourth Parliament ...

Unknown Dennis wins 2005 Muscle Mania  Dec 20, 2005
Accra Daily Mail, He told the GNA Sports that the results a was a heart breaking one, having suspended all conjugal rights for the past six month and also switched off his ...

¢171bn Deal Exposed  Dec 29, 2005
Daily Graphic, 6.5 million; School of Allied Health Science, ¢4.2 million, the National Youth Council (NYC), ¢2.5 million; the Ghana News Agency (GNA), ¢2.5 million and ...

Newmont Welcomes Probe Into Faecal Spillage  Dec 16, 2005
Daily Graphic, The Daily Graphic, in its December 15, 2005 issue, carried a Ghana News Agency (GNA) report in which WACAM condemned Newmont for allegedly disposing faecal ...

Fifty pits sunk by small-scale miners sealed  Dec 21, 2005
Accra Daily Mail, When the GNA talked to some of the affected miners they said the Company should have given them foreknowledge of their planned destruction of the pits. ...

Women Advised To Contest Political Positions  Dec 27, 2005
Daily Graphic, In an interview with the Ghana News Agency (GNA) in Sekondi on Saturday, she said the government and various women groups had created the atmosphere for women ...

Woman appeals to IGP to investigate son's assault  Dec 19, 2005
News in Ghana, ...refused the form. Meanwhile, at the time of going to the press, the lost handcuff key had been found and given to the GNA reporter.

Hearts National Chapters Committee clears air  Dec 20, 2005
News in Ghana, A statement signed by Mr Ken Saro-Wiwa, Public Relations Officer of the Club, copied to the GNA Sports said, "We were only making a public acknowledgement of ...

Ex-lawmaker gets probation for election fraud  Dec 22, 2005
Chicago Sun-Times, Three of them -- GNA Trucking, Ignoffo Trucking and R&V Trucking -- had to bribe city officials and donate money to political campaigns in order to stay in the ...

Private transport unions protest over loading points of Metro ...  Dec 22, 2005
Accra Daily Mail, ...and Nana Yaw Fayah, Chairman of the GPRTU Agona Swedru /Accra and Central Regional Chairman PROTOA, respectively, told the Ghana News Agency (GNA) at Swedru ...

Mfantseman District Mutual Health Insurance Takes Off  Dec 30, 2005
Ghana News Today - Citi FM, When the GNA visited the Saltpond District Hospital on Wednesday, Mr Hayford Frimpong, Hospital Administrator, said no premium holder had reported for ...

Boxing Promotion Syndicate on talent hunt  Dec 19, 2005
News in Ghana, Mr. Quartey alias "AK", disclosed this to the GNA Sports in Tamale on Friday when he presented boxing equipment valued at about 12 million cedis to the ...

TOR blames shortage of LPG on rush for it by commercial drivers  Dec 22, 2005
Joy Online, Public Affairs Manager of TOR, Mrs Aba Lokko, told the GNA in Tema, TOR had increased the daily supply of LPG from 300 metric tonnes to 500 metric tonnes when ...

Self-confidence and adequate preparation crucial - says OB Amoah ...  Dec 14, 2005
Accra Daily Mail, The Deputy Minister told the GNA Sports in Accra that Italy and the Czech Republic may look favourites on paper "but it's for us to go there and prove to the ...

National Centers for Disease Control Issues Flu Alert  16 Jan 2006
WFMZ-TV Online, The cdc says the drugs Tamiflu and Relenza stop the influenza virus from growing and are most effective if taken within the first 24 hours. ...

Doctors Warned Not to Use Two Flu Drugs  16 Jan 2006
WBAY, It's a partial concern because it may increase the use of new, popular, and more expensive drugs like Tamiflu and Relenza that do work, but those are still in ...

Health Highlights: Jan. 16, 2006  16 Jan 2006
Forbes But Schaffner said doctors still have other weapons to fight the flu. One is the antiviral Tamiflu. Another is the drug Relenza, the AP said.

ITRI announces breakthrough in anti-flu Relenza production  Dec 22, 2005
TMCnet ...(China Post)The Industrial Technology Research Institute (ITRI) yesterday announced it had figured out the way to produce Relenza, an anti-viral pharmaceutical ...

Bird Flu: Tamiflu and Relenza for Prevention and Treatment  Dec 21, 2005
SciScoop, ...two newer, more expensive and more effective drugs, Roche's oseltamivir (brand name: Tamiflu), and GlaxoSmithKline's zanamivir (brand name: Relenza; must be ...

Flu season  Jan 13, 2006
Pentagram, Two other antiviral medications, Oseltamavir (Tamiflu) and Zanamavir (Relenza), would probably work to treat flu caused by the H5N1 virus, though studies still ...

Pharmaceutical giants look after their own  Jan 10, 2006
Financial Times, Some drug companies have the advantage of making products that would be directly relevant. “I keep a box of Relenza in my fridge,� says Jean-Pierre Garnier ...

We need a backup drug to face bird flu epidemic, says professor  Jan 11, 2006
TMCnet Professor Hugh Pennington said that Tamiflu, the Government's sole weapon in the potential war on bird flu, needs a backup drug, Relenza. ...

Shortage of bird flu drugs  Jan 10, 2006
Australian Financial Review, ...ago the federal Health Minister, Tony Abbott, stated that Australia had stockpiled at least one course of the antiviral drugs, Tamiflu or Relenza, for almost ...

Campus labs hit the jackpot  Jan 13, 2006
Brisbane Courier Mail, Tissue Therapies, Relenza, Resmed, Farmacule, Papyrus Australia, Alchemia, Medica and Xenome are just a few of the companies that have been spun out of various ...

Flu virus staying away ... for now  Jan 9, 2006
Chambersburg Public Opinion, Another antiviral treatment, Relenza, treats influenza A and B flu virus infections in children 7 and older and adults who have uncomplicated flu infections. ...

BIRD FLU: A RACE AGAINST TIME  Jan 14, 2006
Sunday Herald, ...“The other good news is that it is not drug-resistant. Either of the anti-virals, Tamiflu or Relenza, would inhibit this new strain. ...

Nation-World digest  Jan 15, 2006
Chicago Daily Southtown, Health officials had hoped to conserve use of two newer antiviral drugs, Tamiflu and Relenza, because they show activity against bird flu, unlike the older ...

Missed Target  Jan 15, 2006
Slate ...and rimantadine. Instead of these medications, doctors should prescribe oseltamivir (Tamiflu) and zanamivir (Relenza). Iran's President ...

Bird flu: Much ado about nothing  Jan 1, 2006
Capitol Hill Blue, ...town. GlaxoSmithKline's drug Relenza also appears effective in reducing avian flu symptoms and death after exposure to the virus. ...

Geo firm Releases 11 New Web Sites  Dec 21, 2005
PR Web (press release), Relenza is dedicated to aiding the consumer in their search for Relenza. Established in 2005, Relenza ( http://www.relenza-in ...

France releases updated bird flu pandemic plan  Jan 11, 2006
Forbes Reserves of the antiviral drugs Tamiflu and Relenza, which stand at around 14 mln courses today, will rise to 33 mln in 2007 for a population of 60 million, he ...

France reinforces preparation for fight against eventual flu ...  Jan 11, 2006
People's Daily Online, In 2007 France will have a reserve of 33 million antiviral drugs Tamiflu and Relenza, which stand at around 13.8 million doses in 2005. ...

Biotechs come back to life  Jan 10, 2006
The Age, ...up 14.5 per cent). Leading the surge was drug maker Biota Holdings, manufacturer of flu antiviral Relenza. Biota's share price soared ...

Flu season off to slow start in Virginia  Jan 8, 2006
Richmond Times Dispatch, Treatment options other than Tamiflu include bed rest and pain relievers and the anti-viral drugs amantadine, rimantadine and Relenza. - AJ Hostetler.

United front on bird flu  Jan 11, 2006
The Herald, Factories producing relevant anti-virals (Tamiflu and Relenza) are expanding production, but no effective vaccine can be developed until we know what strain to ...

Consumer Reports Medical Guide Answers Bird Flu Questions  Jan 11, 2006
PNN, ...to Consumer Reports Medical Guide can read the facts about different types of antiviral drugs such as oseltamivir (Tamiflu) and zanamivir (Relenza) and access ...

How to flee from the flu  Jan 10, 2006
Enid News & Eagle, ...medications. The FDA has approved four antiviral drugs for the treatment of the flu: Tamiflu, Flumadine, Symadine, and Relenza. ...

Bird Flu and Tamiflu Update  Jan 3, 2006
SciScoop, I have discussed Tamiflu (oseltamivir) and Relenza (zanamivir) previously - see Bird Flu: Tamiflu and Relenza for Prevention and Treatment in the Articles ...

Worrisome mutation found in bird flu virus  Jan 13, 2006
National Post, ...drugs that target flu, both the adamantanes (amantadine and rimantadine) and the neuraminidase inhibitors (oseltamivir or Tamiflu and zanamivir or Relenza). ...

Hopes over effective bird flu treatment  Jan 13, 2006
Guardian Unlimited, Both anti-virals currently being stockpiled by governments for treating bird flu, Tamiflu and Relenza, are neuraminidase inhibitors, which prevent new virus ...

Some hard truths about bird flu  Jan 13, 2006
Taipei Times, Damascus, Baghdad and beyond. The anti-flu drugs Tamiflu and Relenza are extremely expensive and in short supply. History suggests that ...

Sanofi to seek flu vaccine approval  Jan 13, 2006
International Herald Tribune, ...pandemic. Sanofi stock rose 26 percent last year. Glaxo, helped by demand for its Relenza flu treatment, gained 20 percent. Roche's ...

More evidence bird flu can evade drug: report  Dec 21, 2005
Reuters.uk, ...as neuraminidase inhibitors -- Roche and Gilead Science's Tamiflu, known generically as oseltamivir, and GlaxoSmithKline and Biota's Relenza, known generically ...

Doctors find more evidence bird flu can evade drug  Dec 21, 2005
Reuters AlertNet, ..."The neuraminidase inhibitors (such as Tamiflu and Relenza) are really important, really effective drugs and we need not to lose sight of that. ...

Personal Stockpiling May Lead To Tamiflu-Resistant Influenza  Dec 26, 2005
Medical News Today (press release), Neuraminidase inhibitors oseltamivir and zanamivir, marketed as Tamiflu and Relenza, respectively, are preferable to the older line of antiviral drugs known as ...

Tamiflu-resistant bird flu alarms experts  Dec 22, 2005
Oxford Press, The other is zanamivir, which is marketed in the United States by GlaxoSmithKline as Relenza. No incidents of flu resistant to Relenza have been reported. ...

More evidence bird flu can evade drug - report  Dec 21, 2005
Reuters GlaxoSmithKline (GSK.L: Quote, Profile, Research) (GSK.N: Quote, Profile, Research) and Biota's (BTA.AX: Quote, Profile, Research) Relenza, known generically ...

Avian Flu Deaths Linked to Tamiflu Resistance  Dec 21, 2005
MedPage Today, ...formed viral particles. (The other is Relenza (zanamivir), which is currently available only in inhaled form.). The availability ...

More evidence for H5N1 virus mutation  Dec 26, 2005
VietNamNet Bridge, Only neuraminidase inhibiting substances, such as Roche’s Tamiflu, GlaxoSmithKline’s Gilead Science and Biota’s Relenza have proven effective. ...

Institute masters another flu drug  Dec 22, 2005
Taipei Times, ...工業技術研究院) yesterday said that, after mastering the manufacturing process for Tamiflu, it has now also solved the manufacturing process for Relenza ...

Deaths of treated patients alarm bird flu experts  Dec 22, 2005
Sydney Morning Herald, ...suggested by an earlier case in Vietnam had already prompted the Australian Government to acquire more stocks of a rival antiviral drug, Relenza, a Health ...

BIRD FLU TERRORS MOSTLY MYTH  Jan 3, 2006
Free Market News Network, ...of its failure so far to control the disease in Asia) is far from being "the only antiviral game in town." He notes the GlaxoSmithKline's drug Relenza, as well ...

Bird flu study shows virus evolution in action  Dec 21, 2005
Reuters AlertNet, Tamiflu and the other neuraminidase inhibitor, Relenza, block the neuraminidase enzyme used by the virus and keep the virus from hooking onto the sialic acid ...

Birdflu's tendency to mistakes makes it dangerous  Dec 21, 2005
Reuters Relenza, known generically as zanamivir, was developed by Australia's Biota Holdings (BTA.AX: Quote, Profile, Research) and is marketed by GlaxoSmithKline (GSK ...

Birdflu's tendency to mistakes makes it dangerous  Dec 21, 2005
Reuters Relenza, known generically as zanamivir, was developed by Australia's Biota Holdings and is marketed by GlaxoSmithKline . Relenza ...

Glaxo staff working xmas day on anti-flu vaccine  Dec 24, 2005
NW Evening Mail, ...bird flu pandemic, some of the workforce at GlaxoSmithKline in Ulverston are set to pull out all the stops to ensure production of the drug Relenza can start ...

2 Bird Flu Deaths Despite Tamiflu  Dec 21, 2005
CBS News Tamiflu and another drug, Relenza, are expected to be the front-line defense if that happens, but they must be taken soon after infection to be effective. ...

Bird flu 'resisting antidote'  Dec 21, 2005
Scotsman, National Institute for Medical Research in London, urged the Government to broaden the UK's defence by looking at other option such as the inhaled drug Relenza ...

Bird flu strain develops resistance to drug stockpiled by Britain  Dec 21, 2005
Independent, Relenza, an inhaled drug which works in a similar way to Tamiflu, has not shown signs of triggering resistance but it has been ignored because it is harder to ...

No alarm seen on bird flu  Dec 22, 2005
Boston Globe, GlaxoSmithKline and Biota's Relenza, known generically as zanamivir, is an alternative to Tamiflu and has been shown to be active against Tamiflu-resistant ...

Doubts on Tamiflu as four patients die  Dec 22, 2005
Australian, ...in the journal reinforced calls for alternative approaches to treatment for a pandemic, including the stockpiling of the rival drug zanamivir, or Relenza. ...

Q&A: Your bird flu concerns  Jan 9, 2006
BBC News, ...are immunosuppressants of any use? Apart from Tamiflu there is another anti-viral drug called Relenza which is a nasal spray. Both ...

Tamiflu-resistant bird flu kills 2 in Vietnam Experts assess how ...  Dec 22, 2005
San Francisco Chronicle, Another antiviral drug, Relenza, has also been shown in animal studies to suppress avian influenza -- and researchers say it has a chemical structure that ...

Tamiflu could make avian flu pandemic worse  Dec 22, 2005
New Zealand Herald, Relenza, a drug which works in a similar way to Tamiflu, has not shown signs of triggering resistance but Governments have ignored it because it is harder to ...

Human Bird Flu Cases May Exceed 150, Experts to Meet (Update1)  Jan 11, 2006
Bloomberg ...around the world are planning for a pandemic by stockpiling antiviral drugs such as Roche Holding AG's Tamiflu and GlaxoSmithKline Plc's Relenza, which were ...

Avian flu kills despite Tamiflu  Dec 21, 2005
commercialappeal.com (subscription), Tamiflu and another drug, Relenza, are expected to be the front-line defense if an avian flu pandemic occurs, but they must be taken soon after infection to be ...

UN WARNS BIRD FLU COULD SPREAD  Jan 11, 2006
Special Broadcasting Service, Health Minister Xavier Bertrand has presented an updated plan to tackle, including massive stockpiles of antiviral drugs, like Tamiflu and Relenza, and face ...

Virus fears  Dec 22, 2005
ic Huddersfield.co.uk, ...country, Sir John Skehel, director of the National Institute for Medical Research in London, specifies one alternative in the inhaled drug Relenza - though he ...

Deadly avian flu drug-resistant?  Dec 22, 2005
Philadelphia Daily News, ...influenza. The other is zanamivir, marketed by GlaxoSmithKline as Relenza. No incidents of flu resistant to Relenza have been reported. ...

Greece doing ‘all it can’ to keep bird flu at bay  Jan 12, 2006
Kathimerini, ...relieves the symptoms of sufferers. EOF is also awaiting delivery of 200,000 boxes of Relenza, a similar antiviral drug, he said.

Business takes its shot at pandemic  Jan 9, 2006
Globe and Mail, All of this is spurring governments and health agencies to stockpile as much Tamiflu as they can get from Roche and another antiviral, Relenza, which is made ...

Hope - The Only Defense Against Bird Flu  Jan 11, 2006
Epoch Times, Though the world has steadily been stockpiling the two known anti-viral drugs, Tamiflu and Relenza – they are not vaccines, and by their very nature do not ...

First cases of flu emerging in St. Tammany  Jan 9, 2006
Slidell Sentry News, In most cases the three types of treatments - Tamiflu, Flumadine and Relenza - stop the reproduction of the virus and shorten its course, thus lessening its ...

'Poultry is really safe in Alabama'  Jan 9, 2006
Daily Home Online, ...local health departments. State officials have a stockpile of antiviral medications like Tamiflu and Relenza. Lesinger said indicators ...

EU mulls stockpiling of avian flu drugs  Jan 12, 2006
MarketWatch Stockpiling antivirals at an EU level, which would involve buying drugs like Tamiflu made by Roche Holding AG (RHHBY) and Relenza made by GlaxoSmithKline Plc ...

Patients died despite Tamiflu  Dec 22, 2005
Stuff.co.nz, Tamiflu and another drug, Relenza, are expected to be the frontline defence if that happens, but they must be taken soon after infection to be effective. ...

Tamiflu May Not Be The Answer For Bird Flu  Dec 21, 2005
WAVY-TV, ...disease.". Tamiflu is not the only drug thought to be effective against the bird flu. There is another drug out there called Relenza. It ...

H5N1 Bird Flu Strain Growing Resistance to Tamiflu  Dec 23, 2005
ShortNews.com, Our antiviral strategy is kept under constant review and we are looking carefully at Relenza as a possible back-up to Tamiflu.".

Drug-resistant bird flu killed two Vietnamese  Dec 22, 2005
SciDev.net, In August, researchers suggested in The Lancet that H5N1 would be less likely to become resistant to zanamivir — also called Relenza — than to Tamiflu (see ...

Scientists see holes in bird-flu planning  Dec 28, 2005
Columbus Dispatch (subscription), The development underscored the need for other options in case anti-flu drugs such as Tamiflu and Relenza don’t work or the drugs are in short supply, said Dr ...

Pandemic could force doctors to try experimental therapies  Dec 28, 2005
Bradenton Herald, The development underscored the need for other options in case anti-flu drugs like Tamiflu and Relenza don't work or the drugs are in short supply, said Dr ...

FAQ: Flu Drugs  Dec 23, 2005
Food Consumer, In 1999, FDA approved two additional drugs to fight the flu: Relenza (zanamivir) and Tamiflu (oseltamivir), the first of a new class of antiviral drugs called ...

California Flu: NOT the "Bird Flu", But Still Needs Your Attention  Dec 28, 2005
American Council on Science and Health, There is another effective drug, the inhaled Relenza, which may be available in sufficient quantities to help right here in the US for this flu season. ...

Strain of bird flu resistant to Tamiflu kills two patients  Dec 21, 2005
USA Today Beyond Tamiflu, the Infectious Diseases Society of America recommends stockpiling another antiviral, Relenza, says Andrew Pavia, a member of the group's task ...

Limits found in bird flu drug's use  Dec 21, 2005
International Herald Tribune, There is only one class of medicine that has any effect against the virus and that class contains only two drugs - Tamiflu, made by Roche, and Relenza, made by ...

Flu drug in question  Dec 21, 2005
Newsday, ...form and is not difficult to stockpile. The other antiviral, Relenza, must be inhaled in a mist. Writing in a New England Journal ...

Expert not surprised at Tamiflu resistance  Dec 22, 2005
New Zealand Herald, ...cent of the population. Prof Monto said tamiflu had been selected over the alternative anti-viral drug relenza. "We have selected ...

Melbourne at cutting edge of fight to find vaccine  Jan 5, 2006
The Age, Last month the Federal Government negotiated the purchase of 1.8 million courses of the influenza antiviral Relenza to add to the national stockpile in ...

Top doc criticises pandemic preparedness guidelines  Jan 7, 2006
National Business Review, ...response plans. Another $US1.4 billion will be used for government purchases of antiviral drugs like Tamiflu and Relenza. "If we ...

A Q&A about bird flu and the risks of a pandemic  Jan 2, 2006
The State, I heard that if I take Tamiflu, that will stop the bird flu. A. Stockpiling Tamiflu or Relenza, another antiviral medication, at home is not a good idea. ...

2005 sees pandemic threat explode on public radar; planning ...  Jan 1, 2006
Brooks Bulletin, Urging the business community to prepare contingency plans. Diversifying the cache of antiviral drugs to add Relenza to the stores of Tamiflu. ...

Tamiflu found ineffective in bird flu treatment  Dec 21, 2005
CTV.ca, ...worldwide are scrambling to stockpile Tamiflu, made by Swiss firm Roche AG, as well as another antiflu drug made by GlaxoSmithKline, Relenza, hoping they can ...

The Trouble With Tamiflu  Dec 21, 2005
ABC News The journal reports indicated that a similar drug, Relenza, might not be prone to the same problems, although there is little evidence to confirm that at this ...

Doctors find more evidence bird flu can evade drug  Dec 21, 2005
Khaleej Times, ...“The neuraminidase inhibitors (such as Tamiflu and Relenza) are really important, really effective drugs and we need not to lose sight of that. ...

Bird flu shows resistance to Roche's Tamiflu in Vietnam - UDPATE  Dec 21, 2005
Forbes ...article in the Journal reinforced calls for alternative approaches to treatment for a pandemic, including stockpiling rival drug zanamivir, or Relenza, made by ...

Tamiflu still best hope against bird flu, says WHO  Dec 22, 2005
Guardian Unlimited, Tamiflu. The only other candidate, however, is Relenza, which has limited usefulness because it is administered as a nasal spray. ...

Study shows virus can resist bird flu drug  Dec 22, 2005
Times Online, ..."Tamiflu was chosen on the basis of independent expert advice that reflected its efficacy and ease of administration," she said, adding that Relenza, a flu ...

The bird flu drug race tightens  Dec 22, 2005
CNN ...down $0.19 to $51.00, Research), the British drug giant, also produces an anti-viral for H5N1, an inhalable pharmaceutical known as Relenza, or zanamivir. ...

Victims of bird flu developed resistance to Tamiflu:study  Dec 21, 2005
Investor's Business Daily (subscription) The only other potential defense against avian flu, zanamivir, which is marketed as Relenza by GlaxoSmithKline (GSK), currently requires an inhaler and has not ...

Tamiflu Fails To Save Two Lives  Dec 21, 2005
MedIndia, ...stockpiled across the world. The other drug which is available to counter the virus is the antiviral Relenza. Medindia on Roche ...

'Don't panic' advice as bird flu shows resistance to Tamiflu  Dec 22, 2005
ic Wales, ...needed. They are urging the Government to broaden the UK's defence by looking at other options such as the inhaled drug Relenza. ...

Flu season  Jan 13, 2006
Pentagram, Two other antiviral medications, Oseltamavir (Tamiflu) and Zanamavir (Relenza), would probably work to treat flu caused by the H5N1 virus, though studies still ...


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