Indication: Used to treat vitamin C deficiency, scurvy, delayed wound and bone healing, urine acidification, and in general as an antioxidant. It has also been suggested to be an effective antiviral agent.
Pharmacology: Ascorbic Acid (vitamin C) is a water-soluble vitamin indicated for the prevention and treatment of scurvy, as ascorbic acid deficiency results in scurvy. Collagenous structures are primarily affected, and lesions develop in bones and blood vessels. Administration of ascorbic acid completely reverses the symptoms of ascorbic acid deficiency.
Mechanism Of Action: In humans, an exogenous source of ascorbic acid is required for collagen formation and tissue repair by acting as a cofactor in the posttranslational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. Ascorbic acid is reversibly oxidized to dehydroascorbic acid in the body. These two forms of the vitamin are believed to be important in oxidation-reduction reactions. The vitamin is involved in tyrosine metabolism, conversion of folic acid to folinic acid, carbohydrate metabolism, synthesis of lipids and proteins, iron metabolism, resistance to infections, and cellular respiration.
Drug Category: ATC:A11GA01; Antioxidants; Essential Vitamin; Free Radical Scavengers; Vitamins (Vitamin C)
Dosage Forms: Capsules, tablets (chewable, immediate and extended release), lozenges, solution, and parenteral injection
Absorption: 70% to 90%
Interactions:
DrugBank: Interactions for Vitamin C
Drug Interactions for Vitamin C:
Limited evidence suggests that ascorbic acid may influence the intensity and duration of action of
bishydroxycoumarin.
Chemical IUPAC Name: 2-(1,2-dihydroxyethyl)-4,5-dihydroxy-furan-3-one
Chemical Formula: C6H8O6
Half Life: 16 days (3.4 hours in people who have excess levels of vitamin C)
Drug Type: Approved Drug
# Accession No: APRD00084
CAS Registry Number: 50-81-7
Vitamin C News (When available)
Update on Gout and Other Crystal-Induced ArthritidesJan 5, 2006 Medscape (subscription) In this regard, the capacity for humans to endogenously produce ascorbate, the second most abundant circulating antioxidant, was lost in evolution before ...
Will Medicine Keep Your Horse Sound?Dec 26, 2005 TheHorse.com, ...standard. Cosequin is the trade name for a specific patented combination of glucosamine, chondroitin sulfate, and manganese ascorbate. ...
Making Lemonade Out of Real Lemons Ross E. Getman15 Jan 2006 Opinion Editorials, ...of NSDA also suggested that benzene formation occurs as an interaction among ingredients in the product for example, sodium benzoate, ascorbic acid and FD&C ...
Internal Soda Co. Docs Explain Origin Of BenzeneDec 24, 2005 RedState.org, New York labs in 1990 and 1991, advised me this Fall that he is shocked to see that there are drinks that still contain the ascorbic acid-benzoate combination ...
Need a boost? Zest assuredJan 13, 2006 Times Online, We also need plenty of vitamin C, aka ascorbic acid, because it influences the production of the protein collagen , which we need for healthy structure and the ...
Dough mixer upgrade package improves bread quality, cuts costsJan 11, 2006 FoodProductionDaily.com, ...company claims that bakers will benefit from increased yield, improved crumb quality and shelf life, as well as a reduction in levels of ascorbic acid necessary ...
Peru exports superfruit camu camu to JapanJan 11, 2006 FreshPlaza, The exports of camu camu fruit, which comes from the Amazone, has a vitamin C grade of 60 times the concentration in ascorbic acid, and it gets more popular. ...
Zila forms scientific boardJan 11, 2006 NutraIngredients-usa.com, Ester-C, meanwhile, is produced by mixing ascorbic acid and calcium carbonate to create a pH neutral form of vitamin C, which helps prevent the stomach ...
Organic food industry continues to grow, as do health claimsJan 11, 2006 Newstarget.com, ...in 2004 in the Journal of Agriculture and Food Chemistry compared organically and conventionally grown yellow plums, finding that ascorbic acid, vitamin E and ...
Water as effective as any detox fad, say scientistsJan 2, 2006 Telegraph.co.uk, It points out that food additives identified by their E-numbers are broadly seen as harmful, even though E300 is ascorbic acid - Vitamin C - and the tocopherols ...
Obagi Medical Products Announces Long-Term Collaboration with ...Jan 3, 2006 PR Newswire (press release), ...launched a new line of Professional-C Serums, at the recent ASPS conference in Chicago, in concentrations of 5%, 10%, 15%, and 20% L-ascorbic acid to provide a ...
Fujitsu's environment conditionerJan 5, 2006 Gizmag, C emissions, have been dubbed "Lemonea" in Japanese, presumably due the fruit's refreshing nature and reputation as a relatively good source of ascorbic acid. ...
EU: Trial winemaking practices become lawJan 4, 2006 just-drinks.com, The practices include the treatment of must and fermenting wine with charcoal, employing L-ascorbic acid, adding dimethyldicarbonate (DMDC) and using yeast ...
Nanotech antioxidant system signals future of food ingredientsJan 6, 2006 FoodNavigator.com, C and vitamin E. These effective antioxidants can enhance each other synergistically in their antioxidative functions, but since ascorbic acid (vitamin C) is ...
Herbs, vitamins, might help PMSDec 21, 2005 Contra Costa Times, Whenever you take your iron pills, try to include acidic foods, such as citrus juice or tomato sauce. Even a vitamin C (ascorbic acid) pill will help. ...
Has the 'organic' label lost its meaning?Dec 15, 2005 Hopewell Valley News, Since 2002, the NOSB has carefully investigated and approved 46 synthetic substances for use in organic foods — things like baking soda and ascorbic acid. ...
Zila’s Ester-C sales slip in US, international strongDec 13, 2005 NutraIngredients-usa.com, ...inefficiencies due to maintenance. For the year as a whole the margin was better (68 percent) thanks to ascorbic acid obtained more cheaply.
Iron Imports. II. Iron uptake at the apical membrane in the ...Dec 13, 2005 AJP-Gastrointestinal & Liver Physiology (subscription) ...metal ions) into enterocytes. Fe(III) must first be reduced by ascorbic acid and surface ferrireductases. Among these is duodenal ...
Legislature: Senator targets WASL testing15 Jan 2006 The Columbian, ...the bar for the highest-achieving students. "It's basically a C-level test," he said Friday. "For those students, it's telling them ...
TAG Marketing Society Meeting Marketing to the C-LevelJan 11, 2006 TechLINKS (press release), Marketing to C-level executives in many cases requires a different approach than marketing to other audiences, and can be a significant challenge for many ...
Business Intelligence Information from Highly Regarded C-Level ...Dec 16, 2005 Business Wire (press release), Inside the Minds provides readers with proven business intelligence from C-Level executives (Chairman, CEO, CFO, CMO, Partner) from the world's most respected ...
eXubrio C-Level Leads Appoints John Klingensmith as PresidentDec 28, 2005 Emediawire (press release), Sales appointment setting company - eXubrio C-Level Leads - serves businesses nationally, and in the Buffalo and Niagara Falls, New York, Markets. ...
Identity Theft Laws Elevate Security to the C-LevelDec 30, 2005 Intelligent Enterprise, ...information. Even if legislators show restraint in demanding new controls, it's time for corporations to create C-level security positions. ...
C-level ranks job hop more readilyDec 26, 2005 Boston Business Journal, Observers agree that executive job movement, from the c-level suite of chief executive officers and chief financial officers down to senior vice presidents and ...
American Companies: FeedbackJan 13, 2006 Line 56 News Outrageously high 'C level' salaries and perks in companies that are laying off people insult the intelligence of employees and stockholders. ...
Financial Executives to Learn Importance of Data Quality in ...Jan 12, 2006 Market Wire (press release) ...information and registration for the free event is available at http://www.firstlogic.com/csuite The executive breakfast is open to C-level executives (CIO, CTO ...
Russo's Lucent Lowers View, Names D'Amelio COOJan 13, 2006 Forbes He's been granted the extra post of chief operating officer, and he'll straddle the two C-level jobs until Lucent names a permanent CFO to replace him in that ...
"Coloreds" Click HereJan 12, 2006 ClickZ News, Additionally, the agency sent a direct mail piece to government officials, high school administrators and C-level executives in Seattle. ...
Study: California tops nation in emergency careJan 10, 2006 The Argus, In other areas, however, California's showing was less impressive. In access to emergency care and patient safety the state's performance sunk to the C level. ...
The Evolution of Metro Ethernet StandardsJan 13, 2006 Billing World, C-level executives of the major RBOCs all have made metro Ethernet announcements, but very few real products are really mature. ...
Why Wait -- Streamphone Wireless Video Call Service is Here TodayJan 13, 2006 Wireless Developer Network ...com, he started his career working for projects under Venrock group and has worked as a venture capitalist, entrepreneur and “C� level officer (CEO, COO ...
Escatec Rep Launches North American WebsiteJan 3, 2006 PCB007 (press release), The firm worked with eXubrio C-Level Leads, LLC, to develop the new website. The website will support a lead generation and appointment ...
Software lets users monitor key performance indicators.Jan 4, 2006 Industrial News Room, January 4, 2006 - Targeted for C-level executives, Corda CenterView(TM) displays business information through drillable interactive graphics to allow managers ...
IMA novices strike silverJan 9, 2006 Tillsonburg News, Thomas. It’s not that Turrill has anything against St. Thomas, previously a ‘B’ class team dropped down to the ‘C’ level this season. ...
Enron Lawyers Want Porn, Drug Testimony AllowedJan 10, 2006 Forbes 28, another C-level rat fled the already-sunken ship: former Chief Accounting Officer Richard Causey pleaded guilty to securities fraud, avoiding other charges ...
Cox' SEC Eyes CEO Pay Disclosure RulesJan 11, 2006 Forbes ...bigs. When companies are flush, of course, shareholders are generally willing to see C-level execs lavished with rewards. Yahoo! ...
'Google Factor' to Drive Tech Exec Hiring in '06Jan 10, 2006 E-Commerce Times Compliance may be an old story, in a sense, but it continues to drive C-level hiring, although not at the levels seen in 2004 and 2005. ...
MindComet Launches Internet Marketing Blogs and Weekly PodcastJan 11, 2006 Market Wire (press release) FL -- (MARKET WIRE) -- 01/11/2006 -- MindComet, The Relationship Agency, has aimed a series of seven blogs and a weekly podcast to C-level executives and ...
Google Becomes an Irresistible ForceJan 2, 2006 TMCnet ...impact will endure because the company and its products and its vision are altering at very fundamental levels the perceptions among C-level folks about ...
What's with the Zab pity partyJan 7, 2006 SaddoBoxing.com How the hell can anybody still be hyping Zab? He just got his ass handed to him against C level opposition. And people are saying he wasn't prepared. ...
Survey: Boards looked beyond top execs in '05Jan 4, 2006 Twin Cities Business Journal, ...and ongoing governance requirements stemming from the Sarbanes-Oxley Act -- it's not surprising that it is now much harder to recruit 'C-level' executives to a ...
The missing linkDec 31, 2005 MIS Magazine, It is also true that some C-level executives may lack sufficient IT know-how to understand the limitations of technology, ask the right questions or make the ...
Eating grapefruit helps fight gum diseaseDec 26, 2005 Food Consumer, ...gum tissue. The current study found eating grapefruit daily increases the serum vitamin C level and relieves periodontitis. In the ...
CFO Turnover Sped Up in DecemberJan 8, 2006 CFO.com Magazine, Last month, a total of 2,127 C-level management positions changed hands. That was down 4 percent from November's total of 2,209, a high for the year. ...
Grapefruits may help fight gum diseaseDec 25, 2005 Webindia123, ...free radical molecules. On average, smokers' vitamin C level was 29 percent lower than that for non-smokers. Eating two grapefruits ...
Grapefruit Fights Gum Disease, Study ShowsDec 27, 2005 HealthCentral.com On average, smokers' vitamin C level was 29 per cent lower than that for non-smokers. Eating two grapefruits a day raised vitamin C levels for all everyone. ...
Eating grapefruit could reduce symptom of gum diseaseDec 28, 2005 ABC7Chicago.com, Smoking is known to increase the risk of gum disease. At the start of the study, smokers' vitamin C level was 29 percent lower than non-smokers. ...
Bob Moore Knows How Not to Get FiredDec 15, 2005 CSO, It's simply not enough data. Every other C-level executive does better than that and takes on the responsibility for defining the risk. ...
Another 'C'hief in IT?Dec 14, 2005 MIS Magazine, By Mary Ann Maxwell. There is an abundance of C-level IT titles, the roles for which are different in each organisation. Mary Ann ...
Type of content: VENDOR WHITE PAPERJan 5, 2006 InformationWeek, There's a big disconnect between C-level executives support of SOA and IT's proficiency in the six SOA domain areas critical to successful implementation. ...
Add new commentDec 30, 2005 Linux Journal On the other hand, if you were to execute a function dynamically using multiple C-level calls, you might want to create a local context and use that instead of ...
Grapefruits may help fight gum diseaseDec 25, 2005 Times of India, In smokers, the level almost doubled, but because they started from a lower baseline their average vitamin C level was still lower than that recorded in the non ...
Grapefruit helps in treating gum diseaseDec 25, 2005 United Press International At the beginning of the two-week study, all participants had low levels of vitamin C in their blood plasma, but smokers' vitamin C level was 29 percent lower ...
Eminent launch of the CXO Network Europe in January 2006Dec 15, 2005 I-Newswire.com (press release) ...(I-Newswire) - London, UK - Networking with and building quality long term relationships with pre-qualified C-Level executives ( CXOs ) from companies of ...
Effective Benefits Communications and Decision Support Solutions ...Dec 16, 2005 Emediawire (press release), ...developed a 4-tiered health care cost containment program that also included a detailed ROI analysis that helped us achieve buy-in from our C-Level executives. ...
Eminent Launch of the CXO Network Europe in January 2006Dec 15, 2005 Newswire Today (press release), Networking with and building quality long term relationships with pre-qualified C-Level executives (CXOs) from companies of similar market capitalisations is ...
No extreme payouts for Burlington brassDec 17, 2005 Houston Chronicle, It typically takes one to three years for a C-level executive, CEO, CFO, COO, etc., to find a comparable job, Crawford said, so the extra payments help bridge ...
Change Those SOX and Expense Those OptionsDec 22, 2005 Electronic News, It has focused attention on the details of reports, reports that are now inspected more closely than before, and C-level executives are demanding more from ...
Lisa Live: Blade RunnersJan 6, 2006 FOX News Taking people (and by people, I mean C-level stars) out of their element and placing them somewhere unexpected usually spells rating success. ...
Security Information and Event ManagemenJan 5, 2006 Sarbanes-Oxley Compliance Journal, ...security and compliance management and a profound understanding of the real-world needs, pain points and security requirements of C-level managers across all ...
Wireless Enterprise World 2006Jan 5, 2006 CRN Australia, ...service provision; workforce mobility; application deployment; devices, logistics and services, Wireless Enterprise World brings together a C-level audience of ...
Pay By Touch forms health care business unit; appoints Steven ...Jan 3, 2006 Finextra (press release), His 20 years of experience also include executive and C-level positions with Model N, Acumen Sciences, Radiology Management Sciences, and Electronic Medical ...
IT Gets Dressed UpJan 6, 2006 CRN, However, cost was a major concern for a midmarket company such as Chaus. “What are C-level executives in the midmarket really concerned with? ...
“Collaborate to Innovate�Jan 4, 2006 Supply & Demand Chain Executive, ...midsize enterprises in all countries. Of course, increasing productivity is an ongoing C-level priority. And it's here that several ...
Working with Chiranjeevi is specialJan 7, 2006 Newindpress, On the demand of the audience, especially women, the ticket price was reduced in most of the ‘B’ and ‘C’ level urban centres. ...
2005 in review - SportsDec 29, 2005 Georgia Straight, Tournament organizer Graham Walker says this makes Bergel “a serious C-level celebrity� and that the game isn’t just for children anymore. ...
Difficult Conversations: Discussing CRM with Your CEO Part Two ...Dec 28, 2005 Technology Evaluation Centers, As discussed in Part One of this series, because of the general political process involved in initiative generation and the assumptions the c-level may hold ...
On the moveDec 19, 2005 Las Vegas Business Press, ...manager. He joins 18 years with Wolfgang Puck. C Level, an ultra boutique and lounge, opened at 750 S. Rampart Blvd., #15. Melt ...
The Jacobson Group Further Expands National Presence Through ...Dec 21, 2005 Business Wire (press release), ...talent acquisition consulting services to insurance and healthcare organizations for their senior-level roles, such as Vice President, C-level and Board Member ...
Eminent launch of the CXO Network Europe in January 2006Dec 16, 2005 24-7PressRelease.com (press release) .../24-7PressRelease/ - LONDON, UK, December 16, 2005 - Networking with and building quality long term relationships with pre-qualified C-Level executives (CXOs ...
SOA's Value isn't for C-holdersDec 23, 2005 Always On Moreover, the vast majority of the C-level executives we spoke with (including a few named Peter) aren't hearing the sweet sound of ROI bells tolling. ...
Cisco jumps into netapp performance marketDec 15, 2005 Techworld.com, ..."But no C-level executive in their right mind is going to look for a truly strategic answer that's embedded exclusively in a single hardware brand.".
Granite Energy, Inc. Becomes Publicly TradedDec 27, 2005 PR Web (press release), ...of Petroleum Geologists, Utah Petroleum Association and the Utah Division of Oil, Gas, Mining, Department of Natural Resources; and C-level officers from ...
Bell festival rings in new yearDec 23, 2005 Ottawa Sun, 2. The Bell OIHF is not just another tourney, and not just because of its massive size, with teams from the house league C level through elite AAA squads from ...
Think of 2005 as Rocket Fuel for 2006 ResolutionsDec 16, 2005 CRM Buyer ...columns, I reported how my dog Juneau received an offer through the mail for a free portal as he had mistakenly ended up on a list as a C-level executive. ...
Toronto lawyer to buy proud Derbys franchiseDec 16, 2005 Mississauga News, After spending a few seasons at the Junior C level, the team moved up to Junior B and dominated the league, winning eight titles over an 11-year period ...
Sol Trujillo's Achilles HeelDec 15, 2005 SmartOffice, The seasoned exec soldiered on through his presentation on one foot telling the assembled C level audience he had suffered the injury to Achilles Heel ...
A Guide Providing Crucial Information about the Provisions of ...Dec 20, 2005 Business Wire (press release), ReedLogic's proprietary SpeedBriefing process has been privately used for years by top C-Level executives (CEO, CFO, CTO, CMO, Partner) from the world's ...
iCIMS President and CEO Recognized as Distinguished Industry ...Dec 13, 2005 Emediawire (press release), Featuring C-Level executives representing some of the nation's top companies, this conference provides a broad yet comprehensive overview of implementing ...
Four quick-start steps toward improving asset managementDec 27, 2005 Tech Republic (subscription), For C-level managerial advice, from HR best practices to leadership tips, subscribe to TechRepublic's free CIO Issues newsletter.
Market Watchers Agree: 2006 Heralds GrowthDec 15, 2005 Electronic News, No longer are they getting verbally beat up by C-level executives for having inventory in the warehouse, but they are getting beat up by the company sales ...
A field guide to CMOsDec 20, 2005 HotelMarketing.com It’s not easy to sink your teeth into a role that is still being written. “Of all the C-level positions, it’s exponentially harder to place a marketer ...
Taking Risk Management Beyond Legislative and Regulatory ...Dec 14, 2005 Sarbanes-Oxley Compliance Journal, ...and document risks and controls and monitor those enterprise risks has created an opportunity for risk managers to become involved in C-level strategy and ...
Ruling a small victoryDec 23, 2005 NorthJersey.com, But how much revenue would the next Mesi match generate in some random state, especially since he'll probably box at best a C-level heavyweight after a two ...
Injury cannot derail guitar's royal familyJan 4, 2006 North County Times, Luckily they belong to "guitar's royal family," which began with Celino's legendary grandfather, Celedonio Romero, and his sons, Celin, Pepe and Angel. ...
Custodial death: Bail for accusedJan 4, 2006 Kerala Online, Advocate Celin Wilfred who appeared for the accused submitted an affidavit stating that no other bail application has been presented in any other court. ...
DRUGS-BOLIVIA: A New Future for Coca LeafJan 10, 2006 Inter Press Service (subscription), Europe by support from governments that are sympathetic to its cause, the director of the Latin American Scientific Research Centre (CELIN), Franklin Alcaraz ...
Local youth prepare for Tuesday livestock showJan 7, 2006 McKinney Courier Gazette, ...“Only a certain percentage [of animals] make it to auction,� said Celin Braswell, an agriculture instructor at MHS. “The best animals make the sale.�. ...
Court Actions received Dec. 12Dec 12, 2005 Reno Gazette Journal, ...panel. Roxny Celin Mejia-Sauceda, 120 days jail, suspended; 48 hours community service; $403; DUI school; victim impact panel. Earl ...
EXXONMOBIL: ExxonMobil's Dewaxing Technology Selected for Two ...Jan 12, 2006 Webbolt Business News (subscription), The MIDW proprietary catalyst also provides a boost in cetane quality while reducing high boiling components to lower the T95 boiling point of the diesel fuel ...
Polar Molecular Holding Corporation Announces Date for Annual ...Jan 10, 2006 Business Wire (press release), ...in fuel economy, up to 60% decrease in emissions, reduced engine octane requirement (3-5 octane numbers), a 2 number increase in Diesel fuel cetane rating, and ...
Clean transport fuels for AustraliaDec 28, 2005 On Line opinion, These include PAH (poly aromatic hydrocarbons and benzene). Cetane No. = A number that indicates how easily diesel combust. A high Cetane No. ...
Total, IOC sign agreement for fuel quality improvementDec 21, 2005 Business Standard, ADON P and ADON D. They will also collaborate on cost-effective sulphur reduction technologies for diesel and on the improvement in the Cetane diesel number. ...
Walker says he's true champion15 Jan 2006 Australian, Davitamon Lotto rider Henk Vogels crossed the line in fifth place, the same time as Van Hout, and was furious when he learned that he could have still won the ...
