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Vardenafil
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DRUG INFO
Vardenafil
Drug Name:
Vardenafil
Indication: Used for the treatment of erectile dysfunction
Pharmacology: Vardenafil is used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension (PAH). Part of the physiological process of erection involves the release of nitric oxide (NO) in the corpus cavernosum. This then activates the enzyme guanylate cyclase which results in increased levels of cyclic guanosine monophosphate (cGMP), leading to smooth muscle relaxation in the corpus cavernosum, resulting in increased inflow of blood and an erection. Vardenafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum. This means that, with vardenafil on board, normal sexual stimulation leads to increased levels of cGMP in the corpus cavernosum which leads to better erections. Without sexual stimulation and no activation of the NO/cGMP system, vardenafil should not cause an erection.
Mechanism Of Action: Vardenafil inhibits the cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum located around the penis. Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and corpus cavernosal smooth muscle. This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells. Cyclic GMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum. The inhibition of phosphodiesterase type 5 (PDE5) by vardenafil enhances erectile function by increasing the amount of cGMP.
Drug Category: Anti-Impotence Agents; Vasoconstrictor Agents; Phosphodiesterase Inhibitors; ATC:G04BE09
Brand Names/Synonyms: Levitra; VARDENAFIL, LEVITRA; VDN; Vardenafil
Dosage Forms: TABLET (5, 10, and 20 mg)
Absorption: Vardenafil is rapidly absorbed with absolute bioavailability of approximately 15%.
Interactions: Interactions for Vardenafil:
Effect of other drugs on Vardenafil
In vitro studies: Studies in human liver microsomes showed that vardenafil is metabolized primarily by cytochrome P450 (CYP) isoforms 3A4/5, and to a lesser degree by CYP2C9. Therefore, inhibitors of these enzymes are expected to reduce vardenafil clearance.
In vivo studies: Cytochrome P450 Inhibitors
Cimetidine (400 mg b.i.d.) had no effect on vardenafil bioavailability (AUC) and maximum concentration (Cmax) of vardenafil when co-administered with 20 mg Vardenafil in healthy volunteers.
Erythromycin (500 mg t.i.d) produced a 4-fold increase in vardenafil AUC and a 3-fold increase in Cmax when co-administered with Vardenafil 5 mg in healthy volunteers. It is recommended not to exceed a single 5 mg dose of Vardenafil in a 24-hour period when used in combination with erythromycin. Ketoconazole (200 mg once daily) produced a 10-fold increase in vardenafil AUC and a 4-fold increase in Cmax when co-administered with Vardenafil (5 mg) in healthy volunteers. A 5-mg Vardenafil dose should not be exceeded when used in combination with 200 mg once daily ketoconazole. Since higher doses of ketoconazole (400 mg daily) may result in higher increases in Cmax and AUC, a single 2.5 mg dose of Vardenafil should not be exceeded in a 24-hour period when used in combination with ketoconazole 400 mg daily.
HIV Protease Inhibitors: Indinavir (800 mg t.i.d.) co-administered with Vardenafil 10 mg resulted in a 16-fold increase in vardenafil AUC, a 7-fold increase in vardenafil Cmax and a 2-fold increase in vardenafil half-life. It is recommended not to exceed a single 2.5 mg Vardenafil dose in a 24-hour period when used in combination with indinavir.
Ritonavir (600 mg b.i.d.) co-administered with Vardenafil 5 mg resulted in a 49-fold increase in vardenafil AUC and a 13-fold increase in vardenafil Cmax. The interaction is a consequence of blocking hepatic metabolism of vardenafil by ritonavir, a highly potent CYP3A4 inhibitor, which also inhibits CYP2C9. Ritonavir significantly prolonged the half-life of vardenafil to 26 hours. Consequently, it is recommended not to exceed a single 2.5 mg Vardenafil dose in a 72-hour period when used in combination with ritonavir.
Other Drug Interactions: No pharmacokinetic interactions were observed between vardenafil and the following drugs: glyburide, warfarin, digoxin, Maalox, and ranitidine. In the warfarin study, vardenafil had no effect on the prothrombin time or other pharmacodynamic parameters.
Effects of Vardenafil on other drugs
In vitro studies: Vardenafil and its metabolites had no effect on CYP1A2, 2A6, and 2E1 (Ki > 100uM). Weak inhibitory effects toward other isoforms (CYP2C8, 2C9, 2C19, 2D6, 3A4) were found, but Ki values were in excess of plasma concentrations achieved following dosing. The most potent inhibitory activity was observed for vardenafil metabolite M1, which had a Ki of 1.4 uM toward CYP3A4, which is about 20 times higher than the M1 Cmax values after an 80 mg Vardenafil dose.
In vivo studies: Nitrates: The blood pressure lowering effects of sublingual nitrates (0.4 mg) taken 1 and 4 hours after vardenafil and increases in heart rate when taken at 1, 4 and 8 hours were potentiated by a 20 mg dose of Vardenafil in healthy middle-aged subjects. These effects were not observed when Vardenafil 20 mg was taken 24 hours before the NTG. Potentiation of the hypotensive effects of nitrates for patients with ischemic heart disease has not been evaluated, and concomitant use of Vardenafil and nitrates is contraindicated.
Nifedipine: Vardenafil 20 mg, when co-administered with slow-release nifedipine 30 mg or 60 mg once daily, did not affect the relative bioavailability (AUC) or maximum concentration (Cmax) of nifedipine, a drug that is metabolized via CYP3A4. Nifedipine did not alter the plasma levels of Vardenafil when taken in combination. In these patients whose hypertension was controlled with nifedipine, Vardenafil 20 mg produced mean additional supine systolic/diastolic blood pressure reductions of 6/5 mm Hg compared to placebo.
Alpha-blockers: When Vardenafil 10 or 20 mg was given to healthy volunteers either simultaneously or 6 hours after a 10 mg dose of terazosin, significant hypotension developed in a substantial number of subjects. With simultaneous dosing of Vardenafil 10 mg and terazosin 10 mg, 6 of 8 subjects experienced a standing systolic blood pressure of less than 85 mm Hg. With simultaneous dosing of Vardenafil 20 mg and terazosin 10 mg, 2 of 9 subjects experienced a standing systolic blood pressure of less than 85 mm Hg. When Vardenafil dosing was separated from terazosin 10 mg by 6 hours, 7 of 28 subjects who received 20 mg of Vardenafil experienced a decrease in standing systolic blood pressure below 85 mm Hg. In a similar study with tamsulosin in healthy volunteers, 1 of 24 subjects dosed with Vardenafil 20 mg and tamsulosin 0.4 mg separated by 6 hours experienced a standing systolic blood pressure below 85 mm Hg. Two of 16 subjects dosed simultaneously with Vardenafil 10 mg and tamsulosin 0.4 mg experienced a standing systolic blood pressure below 85 mm Hg. The administration of lower doses of Vardenafil with alpha-blockers has not been completely evaluated to determine if they can be safely administered together. Based on these data, Vardenafil should not be used in patients on alpha-blocker therapy.
Ritonavir and indinavir: Upon concomitant administration of 5 mg of Vardenafil with 600 mg BID ritonavir, the Cmax and AUC of ritonavir were reduced by approximately 20%. Upon administration of 10 mg of Vardenafil with 800 mg TID indinavir, the Cmax and AUC of indinavir were reduced by 40% and 30%, respectively.
Alcohol: Alcohol (0.5 g/kg body weight: approximately 40 mL of absolute alcohol in a 70 kg person) and vardenafil plasma levels were not altered when dosed simultaneously. Vardenafil (20 mg) did not potentiate the hypotensive effects of alcohol during the 4-hour observation period in healthy volunteers when administered with alcohol (0.5 g/kg body weight).
Aspirin: Vardenafil (10 mg and 20 mg) did not potentiate the increase in bleeding time caused by aspirin (two 81 mg tablets).
Other interactions: Vardenafil had no effect on the pharmacodynamics of glyburide (glucose and insulin concentrations) and warfarin (prothrombin time or other pharmacodynamic parameters).
Chemical IUPAC Name: 4-[2-ethoxy-5-(4-ethylpiperazin-1-yl)sulfonyl-phenyl]-9-methyl-7-propyl-3,5,6,8-tetrazabicyclo[4.3.0]nona-3,7,9-trien-2-one
Chemical Formula: C23H32N6O4S
Half Life: 4-5 hours
Drug Type: Approved Drug
# Accession No: APRD00699
CAS Registry Number: 224785-90-4
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Vardenafil News
(When available)
NFL Stiffs Levitra 16 Jan 2006
The Moderate Voice The NFL is taking a hard attitude on Levitra: The National Football League is dropping the erectile dysfunction drug Levitra as a sponsor, saying it has become ...
Ads for erectile drug Levitra less racy now Jan 13, 2006
NorthJersey.com, As sales of impotency drugs have declined and criticism of drug companies' advertising tactics has mounted, the makers of Levitra are taking a more subtle ...
Tagliabue's NFL Too Shy For Racy Levitra Ads Jan 9, 2006
Forbes Neither. So why did the National Football League nix its sponsorship deals with US Levitra marketers Schering-Plough and Bayer (nyse: BAY - news - people )? ...
Levitra’s NFL sponsorship will lapse in month Jan 9, 2006
Boston Herald, The National Football League and the marketers of erectile dysfunction drug Levitra have opted to bench their three-year-old sponsorship deal when it expires ...
NFL, Levitra deal goes soft Jan 10, 2006
Globe and Mail, New York -- The NFL and the marketers of erectile dysfunction drug Levitra have opted to bench their three-year-old sponsorship deal when it expires in March. ...
NFL, Levitra end sponsorship pact Jan 9, 2006
MarketWatch CHICAGO (MarketWatch) -- Citing a shift in the drug's marketing focus, the National Football League will end its sponsorship agreement with Levitra when the ...
NFL dropping Levitra as a sponsor Jan 10, 2006
Bothell Herald, The National Football League is dropping the erectile dysfunction drug Levitra as a sponsor, saying it has become uncomfortable with ads for the product. ...
Warning Label on Levitra Jan 12, 2006
LiveArticles.org, FDA approved three drugs for erectile dysfunction are Levitra, Viagra and Cialis. But the main side effect of all the hree drugs ...
NFL Says 'No More' to Levitra, Other ED Drugs Jan 9, 2006
Media Buyer Planner, ...available for advertising their brands, as the National Football League has chosen not to renew its $18 million sponsorship agreement with Levitra when it ...
NFL REVEALS PLAN TO STIFF-ARM LEVITRA AND NOT RE-UP Jan 10, 2006
New York Post, January 10, 2006 -- The NFL announced yesterday that it does not plan to renew its $6 million-a-year sponsorship deal with Levitra and that it has no interest ...
Insert your joke here: NFL ends deal with Levitra Jan 11, 2006
Kansas City Star, ...at Super Bowl XXXVIII (inadvertent or not), has pulled the plug on erectile disfunction ads and will not renew its 3-year-old sponsorship of Levitra when the ...
Cops Suspended Over Levitra Medication Dec 29, 2005
ABC News John said that shortly after Leonard brought the recovered Levitra medication to the police station to log it as "found property," the officers began joking ...
Cialis and Levitra Could Significantly Challenge Market Leader ... Dec 20, 2005
PR Newswire (press release), ...that although the market for treating erectile dysfunction is dominated by Pfizer's Viagra, the reported efficacy of Bayer/GlaxoSmithKline's Levitra and the ...
Warning Label on Levitra Dec 21, 2005
LiveArticles.org, FDA approved three < A href="http://www.levitratalks.com/">drugs for erectile dysfunction are Levitra, Viagra and Cialis. But the ...
TRI: Erectile Dysfunction Drug Linked to Throat Problem Jan 13, 2006
MedPage Today, 13 - A professional singer who took the erectile dysfunction drug Levitra (vardernafil) woke up the next morning with a vocal cord fold hemorrhage, according ...
What's up with that? Jan 15, 2006
Cincinnati Enquirer, The Associated Press reported this past week that the NFL and the marketers of erectile-dysfunction drug Levitra have opted to bench their 3-year-old ...
NFL ends marketing for erectile dysfunction drugs, saying ads got ... Jan 11, 2006
Pittsburgh Post Gazette, The National Football League says it will not renew a marketing agreement with the makers of the anti-impotence drug Levitra out of concern ads promoting the ...
Levitra: Alternative to Viagra and Cialis Dec 14, 2005
LiveArticles.org, The names of these drugs are Viagra, Cialis and Levitra. ... But other drugs which are giving tough competition to Viagra are Cialis and Levitra. ...
For Impotence Drugs, Less Wink-Wink Jan 9, 2006
New York Times, That contract, with an estimated value of $18 million, was signed in 2003 with Levitra, the third brand in the category, which is sold by Bayer ...
ADVERTISING’S BIG GAME Jan 14, 2006
Amherst Times.com, The question of tastefulness entered into the National Football League's decision to end its sponsorship deal with the impotence drug Levitra; the drug could ...
Pumas pull a U-turn as Tri-Nations beckons Jan 14, 2006
Unison.ie, An advert for GlaxoSmithKline's erectile dysfunction (ED) drug Levitra, which was broadcast during last year's high-profile Super Bowl, caused a rush of blood ...
Cops Suspended Over Levitra Medication Dec 29, 2005
Leading The Charge, BILLINGS, Mont. - The city has disciplined three police officers for mishandling packets of erectile dysfunction medication that ...
Super Bowl Forces New Look at Sexy Ads Jan 12, 2006
FOX News It’s not that the Levitra ad offended me. It didn’t. But cripes — sometimes my kid watches football with me.�. Whyte added ...
NFL Nixes ED Sponsors, Not Ads Jan 10, 2006
Broadcasting & Cable (subscription), The NFL says it will no longer accept sponsorships from the erectile dysfunction category--Levitra, Cialis--but that does not mean you won't see adds for those ...
Magic pills shut out Jan 10, 2006
San Jose Mercury News, ...market concerned about erectile dysfunction. The NFL will soon go snip-snip on its endorsement deal with Levitra. The league doesn't ...
Sports Beat Jan 9, 2006
Seattle Post Intelligencer ...commercials. The league has a three-year deal with Levitra ending in May that it will not renew, and won't seek another such partner. ...
Sex dysfunction drugs: Nowhere to grow? Jan 5, 2006
CNN ...and Levitra from Bayer, GlaxoSmithKline and Schering-Plough -- failed to put the spark back in an industry that might have already reached capacity. ...
Anyone for Fun 'n' games: 1/10/06 Jan 9, 2006
Pittsburgh Post Gazette, It was a match made in advertising heaven -- the NFL's manly audience and erectile dysfunction drug Levitra. But the relationship will peter out in March. ...
The Flip Side Jan 11, 2006
Baltimore Sun, ...in Boogie Nights. The NFL won't renew its three-year sponsorship deal with Levitra when the contract expires in March. The league ...
Shootin' from the lip Jan 14, 2006
Ottawa Sun, ..."The NFL is ending their three-year deal with Levitra,"' says talk-show host Jay Leno. "Apparently there are no hard feelings.".
NFL Goes Soft On Erectile Drug Deals Jan 9, 2006
Mediapost.com, ...says it will stop selling the category--which brings in $6 million a year to the league--after its three-year deal with GlaxoSmithKline's Levitra expires this ...
Bogus drugs flood the market Jan 11, 2006
Daily Nation (subscription), Although some of its thunder has been stolen by new entrants in the market like Levitra and Cialis, the name Viagra remains synonymous with sex-enhancing ...
NFL DROPS ERECTILE DRUG DEALS Jan 10, 2006
sportbusiness.com The NFL says it will stop selling the category - which brings in $6million a year - after its three-year deal with GlaxoSmithKline's Levitra expires this year ...
Cialis Ads Change Focus Jan 11, 2006
Media Buyer Planner, The National Football League has chosen not to renew its sponsorship agreement with Levitra, the third brand in the category, and has said that it has no plans ...
DemiDose(TM) Pill Splitter Allays Concern Over Dose Accuracy in ... Jan 11, 2006
Drug Newswire (press release), DemiDose(TM) specifically splits many of the highest priced brand name prescription pharmaceutical tablets, eg, Cialis(R), Fosamax(R), Levitra(R), Lipitor(R ...
2 Minute Drill -- Published January 12th, 2006 Jan 12, 2006
Stockton Record, The image-conscious NFL (did someone say Love Boat?) has decided to drop Levitra commercials and opt out of a three-year contract. ...
Edwards takes over as Kansas City coach Jan 9, 2006
commercialappeal.com (subscription), Levitra deal off: The National Football League and the marketers of erectile dysfunction drug Levitra have opted to bench their three-year-old sponsorship deal ...
Business Briefs Jan 9, 2006
Topeka Capital Journal (subscription), NFL BACKS AWAY FROM MARKETING DEAL: The National Football League and the marketers of erectile dysfunction drug Levitra have opted to bench their three-year ...
Sports gallery Jan 10, 2006
Concord Monitor, NEW YORK - The National Football League and the marketers of erectile dysfunction drug Levitra have opted to bench their three-year old sponsorship deal when ...
The Billings Gazette Dec 29, 2005
Montana Forum, 28 after Eckhardt and Bechtold were found to have taken sample packets of the prescription medication Levitra, which is used to treat erectile dysfunction. ...
Super Bowl XL countdown Jan 10, 2006
Detroit Free Press, The NFL won't have male impotence drug Levitra as a sponsor after the season, citing what the league considers to be risque advertising. Risque? ...
Business notebook Jan 10, 2006
Boston Globe, Lasted 3 years: The National Football League and the marketers of erectile dysfunction drug Levitra have opted to end their three-year old sponsorship deal ...
Phillips meets with Pack Jan 10, 2006
Chicago Tribune, Samaritans. . . . The NFL and the marketers of erectile dysfunction drug Levitra will end their three-year association in March.
Psychological cure for Impotence Dec 31, 2005
24-7PressRelease.com (press release) Apart from branded medications such as Viagra, Levitra, and Cialis, the generic form of erectile dysfunction drugs are also of immense benefits. ...
Taylor Fined $17,000 Jan 10, 2006
Hartford Courant, The NFL will end its three-year sponsorship agreement with the marketers of the male impotence drug Levitra, citing what the league considers to be risque ...
Redskins' Taylor fined $17,000 for spitting Jan 10, 2006
philly.com, The NFL and the marketers of erectile dysfunction drug Levitra have opted to bench their 3-year old sponsorship deal when it expires in March. ...
Howard Gensler | Pink & Carey Hart tie the knot Jan 9, 2006
Philadelphia Daily News, ...made it all possible. And what about the scientists behind Viagra and Cialis and Levitra? Where were their prizes? Although many of ...
Sex in the golden years: Yes, seniors, the dangers are real Jan 10, 2006
Naples Daily News (subscription), Viagra, Cialis and Levitra, which are designed to help men with erectile dysfunction, had combined global sales of about $2.5 billion in 2004, according to the ...
Mayor Michael R. Bloomberg Declares January 10, 2006 'BBDO Day' in ... Jan 10, 2006
Yahoo! News (press release) ...new business. New accounts included eBay, E*TRADE FINANCIAL, Levitra, Lowe's, Mitsubishi and Motorola, among others. In addition ...
Inside the Baseball Hall of Fame Vote Jan 12, 2006
SportsFan Magazine, Too much has been made over the announcement that the NFL will not renew its "partnership" with Levitra as the official erectile dysfunction medicine for the ...
Dick Clark celebrates 239th New Year Jan 11, 2006
Baraboo News Republic, ...congressman you buy. The NFL canceled Levitra ads Monday because the campaign promotes a lustier sex life. It is unfair. If the ...
Impotence: is it a sign of heart disease? Jan 9, 2006
Times Online, Even more remarkable is the difference that the advent of Viagra, Cialis and Levitra have made to both the understanding and treatment of impotence.
Super Bowl no longer 'right moment' Jan 6, 2006
Indianapolis Business Journal, 10. Cialis competitors Viagra and Levitra may join it on the bench, as the pharmaceutical industry trends away from broadcast TV ads and toward more targeted ...
Officers suspended for mishandling erectile dysfunction pills Dec 30, 2005
Helena Independent Record, ...leave Oct. 28 after an investigation revealed Eckhardt and Bechtold took sample packets of the prescription medication Levitra. The ...
What I've Learned: BB King Dec 16, 2005
Smartmoney.com ...your lapel. I have an excellent medical team. There's Dr. Viagra, Dr. Cialis, and nurse Levitra. They keep me, er, straight. The ...
DemiDose(TM) Pill Splitter Allays Concern Over Dose Accuracy in ... Jan 11, 2006
Yahoo! News (press release) TM) specifically splits many of the highest priced brand name prescription pharmaceutical tablets, eg, Cialis®, Fosamax®, Levitra®, Lipitor®, Norvasc ...
NEWS SNAP:Bayer Healthcare Fills Its Pipeline -2 Jan 5, 2006
Business Online, Bayer Healthcare had high hopes for erectile dysfunction drug Levitra to be a blockbuster, but that drug only achieved nine-months sales in 2005 of EUR190 ...
A smorgasbord of sensationalism Jan 1, 2006
Beckley Register-Herald (subscription), Two Montana police officers were suspended for two weeks without pay after taking packets of Levitra — an erectile dysfunction medicine — from the station ...
[FOCUS]Korea must invent new mousetraps Jan 6, 2006
Joongang Ilbo, ...the development and approval by Korean drug regulators of a new treatment for male erectile dysfunction, a market now dominated by Viagra, Levitra and Cialis. ...
Clip and save this: There'll be a quiz later Jan 8, 2006
Los Angeles Daily News, The NFL won't accept sponsorship from erectile-dysfunction drug manufacturers after its current $6 million-a-year deal with the makers of Levitra runs out this ...
Big Pharma Seeks an Image Cure Jan 3, 2006
Infoshop News Bayer HealthCare, a unit of Bayer (BAY ) and the maker of Levitra, has drawn a lot of attention in recent days -- not all of it flattering -- for hiring Jerry ...
Viagra's on the way to India, but there's stiff competition Dec 21, 2005
Australian, ...tadalafil. Bayer and GlaxoSmithKline sell yet another impotence drug vardenafil under the brand names Levitra and Vivanza. Copies ...
Anti-impotence drug by S.Korea's Dong-A aims for US Dec 30, 2005
Malaysia Star, The other notable erectile dysfunction drugs are Levitra sold by Bayer AG, GlaxoSmithKline Plc and Schering-Plough Corp. Cialis is sold by Icos Corp. ...
Beyond Viagra: the Cupid chemicals Dec 22, 2005
Kansas City Star, Their experimental chemistry follows the trail of the male-centered miracles of Viagra, Cialis and Levitra that stimulate genital blood flow — a class of ...
Data Show Cost-Effectiveness of NitroMed's BiDil Through Reduced ... Dec 13, 2005
PharmaLive.com (press release), Augmentation of the vasodilatory effects of isosorbide dinitrate by phosphodiesterase inhibitors (eg, Viagra(R)/Revatio(TM), Levitra(R), Cialis(R)) could ...
(PRN) - United Heritage Corporation Announces the Completion of ... Dec 20, 2005
Bolsamania.com, ...[+]. (PRN) - Cialis and Levitra Could Significantly Challenge Market Leader Viagra for Treatment of Erectile Dysfunction ... [+. ...
Male Sexual Problem Dec 16, 2005
LiveArticles.org, ...drugs. The FDA has approved three oral medicines for the treatments of erectile dysfunction such as Levitra , Cialis and Viagra. ...
Local Pharmacists Want Internet Drug Stores Banned Dec 28, 2005
The Bahama Journal, ...comes after a number of online pharmacies have started catering to the Bahamian market, offering a growing list of drugs, such as Viagra, Levitra, Vioxx and ...
Diet Pills Popular Among Celebrities Dec 23, 2005
LiveArticles.org, ...information on weight loss, men's health, sexual health, and online prescription drugs like Cialis, Phentermine, Tamiflu, Influenza and Levitra by latest news ...
Pharmaceutical firms vie for new drugs Dec 25, 2005
Korea Herald (subscription), The world's fourth pill for treating erectile dysfunction, Zydena competes against Pfizer's Viagra, Bayer and GlaxoSmithKline's Levitra and Lilly's Cialis. ...
Health Providers May Not Pay For Viagra For Cancer Patients Dec 21, 2005
NBC4.TV, ...attitude. Every company is different, Hensel reported, so, if you need Viagra, Cialis or Levitra, check the policy ahead of time. ...
NAACP and NitroMed Announce Partnership to Narrow Disparities in ... Dec 14, 2005
NAACP (press release), Augmentation of the vasodilatory effects of isosorbide dinitrate by phosphodiesterase inhibitors (eg, Viagra® /RevatioT, Levitra®, Cialis®) could result in ...
Lawmakers agree to fund Viagra use for another year Dec 13, 2005
Malaysia Star, Lilly & Co. & Co., and Levitra, sold by Bayer AG and GlaxoSmithKline Plc, but marketed in the United States by Schering-Plough Corp.
Lawmakers agree to fund Viagra use for another year Dec 13, 2005
Reuters Other erectile dysfunction drugs include Cialis, sold by Eli Lilly & Co. (LLY.N: Quote, Profile, Research) & Co., and Levitra, sold by Bayer AG (BAYG.DE: Quote ...
Viagra Medicare coverage passes House Dec 14, 2005
United Press International ...earlier this week was continued Medicare and Medicaid coverage for erectile-dysfunction drugs including Pfizer's Viagra, ICOS's Cialis and Bayer's Levitra. ...
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