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Urofollitropin
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DRUG INFO
Urofollitropin
Drug Name:
Urofollitropin
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Indication: For treatment of female infertility
Pharmacology: Used for the treatment of female infertility, urofollitropin or follicle stimulating hormone (FSH) stimulates ovarian follicular growth in women who do not have primary ovarian failure. FSH, the active component of urofollitropin is the primary hormone responsible for follicular recruitment and development.
Mechanism Of Action: FSH binds to the follicle stimulating hormone receptor which is a G-coupled transmembrane receptor. Binding of the FSH to its receptor seems to induce phosphorylation and activation of the PI3K (Phosphatidylinositol-3-kinase) and Akt signaling pathway, which is known to regulate many other metabolic and related survival/maturation functions in cells.
Drug Category: Fertility Agents; gonadotropins (68:18.00)
Brand Names/Synonyms: Follitropin beta chain precursor;Follicle-stimulating hormone beta subunit;FSH-beta;FSH-B; Fertinex (Serono S.A.)
Dosage Forms: POWDER FOR SOLUTION
Absorption: Not Available
Interactions: Not Available
Chemical IUPAC Name: Human follicle stimulating hormone
Chemical Formula: C975H1513N267O304S26 >beta chain
Half Life: Not Available
Drug Type: Approved Drug
# Accession No: BIOD00104
CAS Registry Number: 146479-72-3
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