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Tolazoline
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DRUG INFO
Tolazoline
Drug Name:
Tolazoline
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Indication: For the treatment of pulmonary artery anomalies
Pharmacology: Tolazoline is a pulmonary vasodilator indicated used to decrease pulmonary vascular resistance (PVR) in persistent pulmonary hypertension of the newborn (PPHN).
Mechanism Of Action: Vasodilation by means of a direct effect on peripheral vascular smooth muscle and indirect effects produced, in part, by release of endogenous histamine; tolazoline has moderate alpha-adrenergic blocking activity and has histamine agonist activity. Tolazoline usually reduces pulmonary arterial pressure and vascular resistance.
Drug Category: Vasodilator Agents; Antihypertensive Agents; ATC:C04AB02; ATC:M02AX02
Brand Names/Synonyms: Artonil; Benzazoline; Benzidazol; Benzolin; Benzylimidazoline; CIBA 3259; Dilatol Asi; Divascol; Imidalin; Imidaline; Kasimid; Lambril; None; Olitensol; Peripherine; Phenylmethylimidazoline; Prefaxil; Priscol; Priscoline; Tolazolin; Tolazoline; Vasimid; Vasodil; Vasodilatan
Dosage Forms: LIQUID
Absorption: Not Available
Interactions: Not Available
Chemical IUPAC Name: 2-benzyl-4,5-dihydro-1H-imidazole
Chemical Formula: C10H12N2
Half Life: Not Available
Drug Type: Approved Drug
# Accession No: APRD00170
CAS Registry Number: 59-98-3
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