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Thyrotropin Alfa
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DRUG INFO
Thyrotropin Alfa
Drug Name:
Thyrotropin Alfa
Indication: For detection of residueal or recurrent thyroid cancer
Pharmacology: Binding of thyrotropin alfa to TSH receptors on normal thyroid epithelial cells or on well-differentiated thyroid cancer tissue stimulates iodine uptake and organification. Thyrogen is an exogenous source of human TSH that offers an additional diagnostic tool in the follow-up of patients with a history of well-differentiated thyroid cancer.
Mechanism Of Action: Binds to the thyrotropin receptors found on any residual thyroid cells or tissues. This stimulates radioactive iodine uptake for better radiodiagnostic imaging.
Drug Category: Diagnostic Agents; thyroid function (36:60.00)
Brand Names/Synonyms: Follitropin beta chain precursor;Follicle-stimulating hormone beta subunit;FSH-beta;FSH-B; Thyrogen (Genzyme Inc)
Dosage Forms: POWDER FOR SOLUTION
Absorption: Not Available
Interactions: Not Available
Chemical IUPAC Name: Human alpha thyrotropin
Chemical Formula: C975H1513N267O304S26 >beta chain
Half Life: 5 +/- 10 hrs
Drug Type: Approved Drug
# Accession No: BIOD00020
CAS Registry Number: 9002-71-5
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Thyrotropin Alfa News
(When available)
Genzyme Reports 22 Percent Increase in Fourth-Quarter Revenue Jan 9, 2006
MSN Money Sales of Thyrogen(R) (thyrotropin alfa for injection) increased 18 percent to $21 million in the fourth quarter from $18 million in the same period a year ...
Genzyme's Revenue Set to Climb Jan 9, 2006
TheStreet.com ...increase of 27% to $81 million. Sales of the thyroid drug Thyrogen were up 18% to $21 million. Genzyme issued initial projections of ...
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