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Sertraline
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DRUG INFO Sertraline
Drug Name:
Sertraline
Indication: For the treatment of posttraumatic stress disorder, depression, obsessive-compulsive disorder and panic disorder
Pharmacology: Sertraline, an antidepressant drug similar to citalopram, fluoxetine, and paroxetine, is of the selective serotonin reuptake inhibitor (SSRI) type. Sertraline has one active metabolite and is used to treat depression, obsessive-compulsive disorder (OCD), panic disorder, and post-traumatic stress disorder.
Mechanism Of Action: It is believed that sertraline inhibits reuptake of serotonin at the neuronal membrane. SSRIs have less sedative, anticholinergic, and cardiovascular effects than the tricyclic antidepressant drugs because of decreased binding to histamine, acetylcholine, and norepinephrine receptors.
Drug Category: Antidepressants; Selective Serotonin Reuptake Inhibitors (SSRIs); ATC:N06AB06
Brand Names/Synonyms: Apo-Sertraline; HSDB 7037; Lustral; Sertralina [Spanish]; Sertraline; Sertraline Hydrochloride; Sertralinum [Latin]; Sultamicillin Tosylate; Zoloft
Dosage Forms: Tablets and Oral solution
Absorption: The effects of food on the bioavailability of the sertraline tablet and oral concentrate were studied in subjects administered a single dose with and without food. For the tablet, AUC was slightly increased when drug was administered with food but the Cmax was 25% greater, while the time to reach peak plasma concentration (Tmax) decreased from 8 hours post-dosing to 5.5 hours. For the oral concentrate, Tmax was slightly prolonged from 5.9 hours to 7.0 hours with food.
Interactions: [an error occurred while processing this directive]
Chemical IUPAC Name: 4-(3,4-dichlorophenyl)-N-methyl-tetralin-1-amine
Chemical Formula: C17H17Cl2N
Half Life: 26 hours
Drug Type: Approved Drug
# Accession No: APRD00175
CAS Registry Number: 79617-96-2
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Sertraline News (When available)
Yesterday's results Dec 27, 2005 Times Online, 12.00 (2m 3f 110yd ch) 1, Lustral Du Seuil (MA Fitzgerald, 4-1); 2, Launde (50-1); 3, Latin Queen (33-1). Very Optimistic (4th) 11-8 fav. 10 ran. 9l, 13l. ...
HENDERSON TAKES WELSH OPENER Dec 27, 2005 Sportinglife.com, Lustral Du Seuil gave Nicky Henderson a great start to Welsh National Day at Chepstow when landing the Jim Neville Memorial Beginners' Chase under Mick ...
Recent winners highlight relatives on offer at Karaka Dec 28, 2005 ThoroughbredNews.co.nz, 2070m). Trained by Nikki Blatch, Likes To Rule defeated Mactomack (Frenchpark x Lustral) and Get Up (Turbulent Dancer x Get Down). ...
Sett a trap for the Warwick bookies Dec 30, 2005 Guardian Unlimited, That could prove to be decent form and fourth-placed Lustral Du Seuil gave it a timely boost when successful at Chepstow earlier this week. ...
Racing: Solzen does it his way Dec 28, 2005 ic Wales, Triumph.�. Henderson and Fitzgerald had initiated a double when Lustral Du Seuil landed the Jim Neville Memorial Beginners’ Chase. ...
Snacking the Night Away 16 Jan 2006 Washington Post, A small study at the University of Pennsylvania found that the antidepressant Zoloft may help treat night-eating syndrome. While ...
Talk Therapy Needed With Medication For Depression 16 Jan 2006 WCCO, Three months ago, McMenamin started seeing a new doctor. "Right away he put me on Zoloft," she said. "He didn't even know me for an hour and he put me on it.". ...
Generics bolster drugstore profits Jan 15, 2006 Fort Wayne Journal Gazette, ...two of the top 10 selling drugs in the United States – Merck & Co.’s cholesterol pill Zocor and Pfizer Inc.’s antidepressant Zoloft – lose exclusivity. ...
Witness: Mom thought killings 'right' Jan 13, 2006 St. Augustine Record, Complaining of depression and panic attacks, Demeniuk received prescriptions for Zoloft, a selective serotonin reuptake inhibitor (SSRI), and Xanax, an anti ...
Local Doctor Convicted On Healthcare Fraud Charges Jan 13, 2006 NewsNet5.com, ...pain. Prosecutors say he often prescribed medication such as OxyContin, Zoloft and Valium to people already hooked on drugs. But ...
Doctor convicted of fraud in prescribing painkillers Jan 13, 2006 WTOL, ...pain. Prosecutors say Martinez often prescribed medication such as OxyContin, Zoloft and Valium to people already hooked on drugs. ...
'Why did I kill my babies?' Jan 10, 2006 St. Augustine Record, She came back with some samples and a prescription for Zoloft, he said. ... She went to the doctor's office and changed Zoloft for Paxil. ...
Pharmacists Give Away Meds Amid Medicare Confusion Jan 12, 2006 ABC News Chad Worz, an Ohio pharmacist who sees many dual eligibles, says this has happened often with the antidepressant Zoloft. "I won't ...
The fool's gold that heals Jan 13, 2006 Guardian Unlimited, 6.67 points. The scores for Zoloft were 9.96 (placebo, 7.93); Effexor, 11.54 (placebo, 8.38); Celexa, 9.69 (placebo, 7.71). The ...
Boyfriend Of Woman On Trial In Sons' Murder Says Drugs Changed Her ... Jan 9, 2006 News4Jax.com, ...found the boys dead. He said he had asked her to give him back his Zoloft, because he thought she was taking too many. Also on Monday ...
Pharmacies see profits spike thanks to sales of generic drugs Jan 10, 2006 Salem News, The increased sales of generics, expected to continue this year as more drugs including Zocor and Zoloft come off patent protection, come as retail pharmacies ...
Prosecution Rests, Defense Presents First Witnesses In Demeniuk ... Jan 11, 2006 News4Jax.com, Demeniuk's attorneys argued that the combination of two anti-depressants Zoloft and Paxil, along with the sedative Zantac and alcohol, contributed to her ...
Pfizer struggles as generics pummel its drugs Jan 6, 2006 Pittsburgh Post Gazette, ...remedies for common ailments. Among them were Celebrex for pain, Zoloft for depression and Viagra for impotence. Its key weapon ...
US analysts: Good year expected for Teva Jan 2, 2006 Ynetnews, Generic drug makers are gearing up for a big year as blockbuster brand-name medicines such as Zocor, Zoloft, Pravachol and Ambien are set to lose US patent ...
Paper cites drug ads for improper diagnosis Jan 2, 2006 Tallahassee Democrat, They offer Zoloft as one example, quoting a TV commercial that claims depression is a medical condition that may be due to a chemical imbalance, and that ...
Generic-Drug Makers Face a Big Year Jan 3, 2006 Los Angeles Times, NEW YORK — Makers of generic drugs are gearing up for a big year as blockbuster brand-name medicines such as Zocor, Zoloft, Pravachol and Ambien are set to ...
Pfizer to pay $1.3bn for control of diabetes drug Jan 13, 2006 MSN Money The company faces about $14bn worth of lost sales over several years because of patent expiries on other key drugs, including Zoloft, Zithromax and Norvasc. ...
Live happy Jan 7, 2006 Globe and Mail, ...'Your home should be like a good dose of Zoloft,' potter-turned-design-guru Jonathan Adler says in his new book. So embrace your love of cabbage roses. ...
Jury blames doctor in deaths, fraud Parma doctor's fraud proves ... Jan 13, 2006 Cleveland Plain Dealer, ...have to die.". Martinez often prescribed medication such as OxyContin, Zoloft and Valium to people already hooked on drugs. But he ...
A Boost From Generics Jan 13, 2006 Hartford Courant, ...including two of the 10 top-selling drugs in the United States - Merck & Co.'s cholesterol pill Zocor and Pfizer Inc.'s antidepressant Zoloft - lose exclusivity ...
Defense puts drugs on trial Jan 12, 2006 St. Augustine Record, The theory being tested was whether certain antidepressants -- Zoloft and Paxil -- can make some people homicidal or suicidal. ... makes Zoloft. ...
FDA Plan Would Aid Drug Makers In Liability Suits Jan 14, 2006 Wall Street Journal Last July, a federal judge in Minnesota turned down a Pfizer request to bar a suit over the antidepressant Zoloft, writing that "federal labeling laws are ...
TeenScreen - New York Times - Danger Signs Dec 17, 2005 OpEdNews ..."She died of suicide at age 12 years, 3 months," her father explained, "just eight weeks after being put on Paxil and then Zoloft." On January 5, 2000, Caitlin ...
Antidepressants may reduce suicides Jan 1, 2006 International Herald Tribune, The study is likely to increase the controversy over whether depressed teenagers should routinely be prescribed newer antidepressants like Paxil and Zoloft. ...
Generic cos hope for a rocking '06 Jan 2, 2006 Economic Times, NEW YORK: Generic drugmakers are gearing up for a big year as blockbuster brand-name medicines such as Zocor, Zoloft, Pravachol and Ambien are set to lose US ...
Antidepressants appear to reduce risk of suicide Jan 1, 2006 Salt Lake Tribune, The study is likely to increase the controversy over whether depressed teenagers should routinely be prescribed newer antidepressants like Paxil and Zoloft. ...
Antidepressants cut suicidal tendencies, says study Jan 1, 2006 Earthtimes.org The study, by Group Health Cooperative (GHC) researchers, also said that new antidepressants like Paxil and Zoloft were better than older ones where low ...
A New Year’s Resolution Jan 4, 2006 PR Web (press release), Although medications such as Effexor, Prozac, Paxil, Wellbutrin, Zoloft and Celexa are considered non-addictive, there are many people who describe vast swings ...
Walgreen First Quarter Earnings Call Jan 5, 2006 123Jump.com, The company anticipates that with the introduction of the generic drugs – Zocor and Zoloft – in the later part of the year, their share could be about 7 ...
Goodbye 2005 — Hello 2006! Jan 2, 2006 The Trentonian, Last year, 2005 (remember it? I do, like it was yesterday) was so crazy I should be popping Zoloft like they were Tums. Instead, I ...
The antidepressants to watch in '06 Jan 4, 2006 CNN Zoloft, an antidepressant from Pfizer (up $0.46 to $23.78, Research), the world's biggest drug maker, has strong name recognition. ...
Walgreen quarterly profit rises 5 percent Jan 3, 2006 ABC News ...equal about 7 percent of the total prescriptions it fills, though the biggest, generic versions for cholesterol drug Zocor and antidepressant Zoloft, are not ...
Suicide Drops With Antidepressant Use Jan 3, 2006 WebMD The 10 drugs identified by the FDA are Prozac, Paxil, Zoloft, Effexor, Celexa, Lexapro, Luvox, Remeron, Serzone, and Wellbutrin. ...
Generic-drug bonanza in 2006 may not lift stocks Dec 30, 2005 San Diego Union Tribune, NEW YORK – Generic drugmakers are gearing up for a big year as blockbuster brand-name medicines such as Zocor, Zoloft, Pravachol and Ambien are set to lose ...
Generic-drug bonanza in 2006 may not lift stocks Dec 30, 2005 Reuters NEW YORK, Dec 30 (Reuters) - Generic drugmakers are gearing up for a big year as blockbuster brand-name medicines such as Zocor, Zoloft, Pravachol and Ambien ...
Health Care Heroes And Has-Beens Dec 29, 2005 Forbes A similar dynamic applies to Pfizer’s depression drug Zoloft, which is nearly identical to drugs (monoamine oxidase inhibitors) introduced more than 40 years ...
End to patents means major headache for drug makers Dec 23, 2005 The Journal News.com, Pfizer Inc., based in New York City, is scheduled to lose patent-protected sales of its antidepressant Zoloft, which had $2.7 billion in US sales last year. ...
Class Action Suit Says Depo-Provera Birth Control Drug Causes ... Dec 21, 2005 Lifesite, ...been filed against the drug company Pfizer, an international pharmaceutical conglomerate that also produces the prescription drugs Viagra, Zoloft and Celebrex. ...
Pfizer to pay French partner 1.3 bln usd for control of diabetes ... Jan 12, 2006 Forbes The report said it suffered about 14 bln usd worth of lost sales over several years because of patent expiries on key drugs, including Zoloft, Zithromax and ...
Generics win on Big Pharma's woes Jan 10, 2006 CNN/Money ...the cardiovascular treatment from Bristol-Myers Squibb (down $0.30 to $22.54, Research) that totaled $2.6 billion in 2004 sales, and Zoloft, the Pfizer (down ...
Bags of evidence opened for Demeniuk jurors Jan 11, 2006 St. Augustine Record, They are arguing that a mix of alcohol and certain anti-depressants -- Zoloft and then Paxil -- created a "substance-induced mood disorder" that drove Demeniuk ...
Jury seated Thursday in Demeniuk trial Jan 6, 2006 St. Augustine Record, Demeniuk had been prescribed Xanax, an anti-anxiety drug, for her depression as well as Zoloft, a selective serotonin reuptake inhibitor (SSRI). ...
DemiDose(TM) Pill Splitter Allays Concern Over Dose Accuracy in ... Jan 11, 2006 PR Newswire (press release), Pravachol Mood Women's Health Antibiotic Allergy Migraine - Zyprexa - Fosamax - Levaquin - Zyrtec - Imitrex Oral - Lexapro - Prempro - Zoloft Individuals who ...
McDermott´s 2005 Top 10 Life Science Decisions Jan 10, 2006 Mondaq News Alerts, ...sertraline hydrochloride. Sertraline hydrochloride is sold by Pfizer under the name ZOLOFT, for which Pfizer holds two patents. Teva ...
Judge says Sliwinski fit to stand trial Jan 12, 2006 Pioneer Press Online, ...certainly.". Lourgos said that Sliwinski was on four drugs when he interviewed her -- Seroquel, Sinequan, Zoloft and Klonopin. He ...
DRL gets tentative US nod for antidepressan Dec 29, 2005 Sify, ...drug sertraline hydrochloride. |Read more Finance news.|. The drug is a generic version of Pfizer Inc.'s Zoloft. Ahead of the news ...
Antidepressants May Spur Brain Cell Growth Dec 27, 2005 Forbes Selective serotonin reuptake inhibitors (SSRIs), a widely used class of antidepressant drugs that include Celexa, Paxil, Prozac and Zoloft, boost nerve fiber ...
SSRI antidepressants actions studied Dec 19, 2005 Monsters and Critics.com, Antidepressants, such as Prozac, Zoloft and Paxil, have been thought to increase synaptic concentrations of serotonin and norepinephrine, enhancing or ...
Dr Reddy's gets tentative nod for antidepressant Dec 30, 2005 Economic Times, ...for antidepressant drug sertraline hydrochloride. The drug is a generic version of Pfizer Inc.'s Zoloft. Ahead of the news, shares ...
Lipitor Patent Win Boosts Pfizer Shares Dec 19, 2005 Leading The Charge, And has sales of key drugs stagnate, Pfizer is losing patent protection on several important products including antidepressant Zoloft, antibiotic Zithromax and ...
Leftover Drugs Are a Prescription for Trouble, Says the Harvard ... Dec 22, 2005 Yahoo! News (press release) But have you ever thought about where the medicine will end up? Scientists are finding everything from aspirin to Zoloft in our streams, rivers, and lakes. ...
Top 10 Charleston-area courtroom cases Dec 31, 2005 Charleston Post Courier (subscription), 1. In February, a Charleston County jury rejected 15-year-old Christopher Pittman's defense that the antidepressant Zoloft made him kill his grandparents. ...
Dowd takes on women in 'Sexes' Dec 17, 2005 commercialappeal.com (subscription), The pharmaceutical industry has been aggressively marketing Vicodin, Zoloft, Paxil and other products promising artificial placidity. ...
Serotonin may not be key to psych drugs Dec 20, 2005 United Press International The new findings contradict the conventional wisdom on how SSRIs work, that the drugs -- including Prozac, Zoloft and Paxil -- increase synaptic concentrations ...
LIFELONG HEALTH : Joyful Christmas season can also bring ... Dec 18, 2005 Arkansas Democrat-Gazette (subscription), ...medications. The most common are drugs called serotonin reuptake inhibitors (SSRIs), such as Prozac, Paxil, Zoloft, Lexapro and Celexa. ...
Climb out of depression with exercise, study says Dec 20, 2005 Green Bay Press Gazette, ...publicized study released five years ago that found that just 10 months of regular, moderate exercise outperformed a leading antidepressant (Zoloft) in easing ...
Black cohosh extract may relieve hot flashes Dec 20, 2005 The Spokesman Review, It runs in my family. The other drug my doctor has suggested is Zoloft. But I am not depressed and don't want to deal with side effects from that drug either. ...
The Drug Dilemma Dec 28, 2005 ABC7Chicago.com, Antidepressants known as SSRIs pose the biggest problem. Those include drugs like Prozac, Paxil, Zoloft and Lexapro. Antihistamines ...
Good counsel: Premenstrual disorders Dec 22, 2005 Rochester Democrat and Chronicle, Medications have been found to be helpful. Antidepressants known as SSRIs, such as Sarafem, Zoloft and Paxil, are approved by the FDA to treat this condition. ...
The Washington Times Needs a Hug Dec 29, 2005 Wonkette (satire), ...surrogate mommy. If we could, we'd prescribe the Times the same Zoloft and Grey Goose martini we start our weekends with. But, fortunately ...
Andy Vickery, lawyer for Christopher Pittman Dec 30, 2005 Charlotte Observer, Pittman's defense team, led by Houston lawyer Andy Vickery, had argued that the antidepressant drug Zoloft caused Pittman, who was 12 at the time, to kill Joe ...
Pfizer invests in personalized medicine company Dec 28, 2005 Ann Arbor News, Pfizer, the New York-based maker of impotence treatment Viagra, the antidepressant Zoloft and the cholesterol-lowering drug Lipitor, also will buy another $25 ...
Follow-up called key in treating depression Jan 1, 2006 Seattle Times, ...by the National Institute of Mental Health, also found the risk of suicidal behavior after starting the newer drugs — including Paxil, Zoloft, Celexa and ...
Walgreen 1st-Qtr Net Rises 5.2% on Generic Drug Sales (Update1) Jan 3, 2006 Bloomberg ...report. New generics including versions of Zocor and Zoloft are expected to be introduced in the company's fiscal year. Drugstore ...
Antidepressants Don't Appear to Raise Suicide Risk, Study Shows Jan 1, 2006 Bloomberg The drugs include in the original FDA warning were Effexor, Prozac, Pfizer Inc.'s Zoloft, GlaxoSmithKline Plc's Paxil, Solvay SA's Luvox, Biovail Corp.'s ...
Antidepressants work almost immediately Jan 4, 2006 Sydney Morning Herald, Other antidepressants include GlaxoSmithKline Plc's Paxil, Pfizer Inc's Zoloft and Forest Laboratories Inc.'s Celexa, among others. ...
Getting the Specifics on Generic Drugs Jan 5, 2006 Forbes Some of these medicines, such as Prozac, have been available in generic versions, while mega-selling Zoloft is set to go off-patent next year, according to Hoey ...
Penn Study Reveals Prevalence Of Night Eating Syndrome Among ... Jan 2, 2006 Science Daily (press release) Recent studies have found the antidepressant setraline (Zoloft®) to significantly improve symptoms of night eating syndrome, including nocturnal ingestion and ...
Depression treatment studied Jan 1, 2006 Dallas Morning News (subscription), While well-known drugs such as Prozac and Zoloft have shown their worth in clinical trials, the performance in actual practice has been less clear. ...
Study counters past data linking antidepressants to increased ... Jan 1, 2006 Baltimore Sun, ...older medications known as tricyclics. The SSRIs include Prozac, Paxil, Zoloft and Celexa. Among children and adolescents, suicide ...
Herb Weisbaum: Some Encouraging News On Treating Depression Jan 5, 2006 KOMO, ...it turns out; the risk of suicidal behavior was the lowest for patients taking 10 of the newest antidepressant, such as Prozac, Paxil, Zoloft, Celexa, Lexapro ...
Prescription for Trouble Jan 8, 2006 ABC30.com, Consumer Reports' Joel Gurin. Zoloft, Effexor, and other antidepressants, particularly when prescribed to young people. With most of ...
Carrollton man arrested on rape, sodomy charges Jan 7, 2006 Madison Courier, The Kentucky State Police seized several prescription drugs, including hydrocodone, Zoloft and Viagra, computer data materials and bed linens from the Fisher ...
Zero Dollars, a Little Talent and 30 Days - Day 27 - Buzzing and ... Dec 23, 2005 Search Engine Guide, ...on content creation to heart, I headed over to Trellian's Keyword Discovery tool to do a little research and found that the phrase "Zoloft and breastfeeding ...
TeenScreen's Pseudo-Scientific Basis Jan 6, 2006 SierraTimes.com ...or disorders], clusters of symptoms presumed to be related, not diseases.� – from Prozac Backlash: Overcoming the Dangers of Prozac, Zoloft, Paxil, and ...
Mind the Meds: Top 10 pharmacy benefits management strategies for ... Jan 5, 2006 Benefitnews.com, ..."Probably the biggest ones are the three Zs, Zithromax, Zoloft and Zocor, which are all going off patent in the next two years," says Matthew Gibbs, national ...
Study Finds ‘Night Eating Syndrome’ Common in People with ... Jan 3, 2006 Newsinferno.com, According to recent study results, both aspects of night eating syndrome respond quite well to the antidepressant Zoloft (setraline).
Attorney: off his medication, man stabs two neighbors Jan 2, 2006 Daily News Tribune, Daniel Westbrook has a history of psychiatric problems including schizophrenia and depression and has not taken his prescribed medication -- Zoloft and Zyprexa ...
DESPERATE HOUSEWIVES� NOT DESPERATE ENOUGH Jan 3, 2006 I-Newswire.com (press release) ...own stash of Xanax, Prozac, Valium, Ativan, Buprenex, Oxycontin, Soma, Hydroxyzine, Ultram, Vicodin, Darvon, Tylenol with Codeine, Percodan, Zoloft, and, of ...
Dads who nurture also deserve our praise Jan 4, 2006 Tallahassee.com, As a pharmacist, I am not convinced that direct-to-consumer advertising of prescription drugs like Zoloft by drug manufacturers is in the public interest, but ...
Antidepressants Don’t Increase Suicide Risk Jan 3, 2006 Christian Broadcasting Network, But new government-sponsored studies on some of the most popular antidepressants, such as Prozac, Zoloft, Celexa, and others, such as Paxil, Lexapro, Effexor ...
The 14 Worst Corporate Evildoers Jan 3, 2006 Axis of Logic, In addition to Viagra, Zoloft, Zithromax and Norvasc, Pfizer produces the HIV/AIDS-related drugs Rescriptor, Viracept and Diflucan (fluconazole). ...
Drug info just a mouse click away Jan 8, 2006 Edmonton Sun, For instance, a search for the antidepressant Zoloft on the site turns up everything from its generic name and other brand names to a diagram of its chemical ...
Forecast 2006: Magazines Jan 2, 2006 MEDIAWEEK (subscription) ...rebounded 9.3 percent over 2004 to $1.8 billion, according to the Publishers Information Bureau, thanks to ads for prescription drugs like Singulair and Zoloft ...
Drug makers face headache as patents expire Dec 18, 2005 Austin American-Statesman (subscription), Pfizer Inc. is scheduled to lose patent-protected sales of its antidepressant Zoloft, which had $2.7 billion in US sales last year. ...
Increased use of generics helps bolster drug store profits Jan 8, 2006 Asbury Park Press, ...two of the top-selling drugs in the United States — Merck & Co.'s cholesterol pill Zocor and Pfizer Inc.'s antidepressant Zoloft — lose exclusivity. ...
All eyes on Pfizer shares after ruling Dec 18, 2005 MSN Money Challenges remain for Pfizer. It is trying to offset the loss of $14bn in annual sales due to patent expiries on drugs such as anti-depressant Zoloft. ...
Drug's patent win heartens Pfizer Dec 18, 2005 Australian, It faces about $US14 billion worth of lost sales over the period of a few years due to patent expiries on other key drugs, including Zoloft, Zithromax and ...
Drugs continue their dive in '05 Dec 20, 2005 CNN International ...on Zithromax, a treatment for bronchitis, pneumonia and other infections that totaled $1.9 billion in 2004 sales, and on the antidepressant Zoloft, which had ...
Neighbor charged in knife attack Dec 31, 2005 Boston Globe, His parents told officials he had been prescribed Zoloft and Zeprexia for his depression, but had stopped taking the medicine six months ago, according to a ...
Depression Weighs Heaviest on the Elderly Dec 31, 2005 PakTribune.com, ...groups of anti-depressant medications are more commonly used among the elderly: SSRIs (selective serotonin reuptake inhibitors) such as Prozac, Zoloft and Paxil ...
Popular Antidepressants Boost Brain Growth, Hopkins Scientists ... Dec 20, 2005 Science Daily (press release) Antidepressants, such as Prozac, Zoloft and Paxil, have long been thought to exert their clinical effects by increasing synaptic concentrations of serotonin ...
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