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Secretin,synthetic
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DRUG INFO
Secretin,synthetic
Drug Name:
Secretin,synthetic
Indication: For diagnosis of pancreatic exocrine dysfunction and gastrinoma
Pharmacology: Used in the diagnosis of pancreatic dysfunction or gastrinoma (stomach cancer), secretin is a hormone produced in the S cells of the duodenum in response to low local pH. It stimulates the secretion of bicarbonate from bicarbonate producing organs(liver, pancreas, Brunner's glands) when the pH drops below a set value. This helps neutralize the gastric acid entering the duodenum from the stomach. It also inhibits acid secretion from the stomach by reducing gastrin release from the G cells of the stomach.
Mechanism Of Action: Secretin binds to the secretin receptor found on the lining of S cells in the duodenum and G cells in the stomach. Binding leads to the secrection of bicarbonate or the reduction of the secretion of gastrin. Properly functioning organs (duodenum, pancreas and stomach) should be responsive to this hormone
Drug Category: Diagnostic Agents; pancreatic function (36:61.00)
Brand Names/Synonyms: Secremax, SecreFlo; Secremax, SecreFlo (Repligen Corp)
Dosage Forms: POWDER FOR SOLUTION
Absorption: Not Available
Interactions: Not Available
Chemical IUPAC Name: Not Available
Chemical Formula: C130H219N43O42
Half Life: Not Available
Drug Type: Approved Drug
# Accession No: BIOD00039
CAS Registry Number: Not Available
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Secretin,synthetic News
(When available)
Repligen Files Infringement Complaint Against Bristol-Myers Squibb ... Jan 6, 2006
Yahoo! News (press release) Repligen has a Specialty Pharmaceuticals business comprised of rProtein A(TM) and SecreFlo®, the profits from which will be used to partially support the ...
Repligen Files Infringement Complaint Against Bristol-Myers Squibb ... Jan 7, 2006
ag-IP-news Agency, Repligen has a specialty pharmaceuticals business comprised of rProtein A and SecreFlo, the profits from which will be used to partially support the ...
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