Secobarbital resources


DRUG INFO
Secobarbital

Drug Name: Secobarbital

Indication: For the Short-term treatment of intractable insomnia for patients habituated to barbiturates



Pharmacology: Secobarbital, a barbiturate, is used for the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful stimuli. Little analgesia is conferred by barbiturates; their use in the presence of pain may result in excitation.

Mechanism Of Action: Secobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged.

Drug Category: Hypnotics and Sedatives; Adjuvants; Barbiturates; ATC:N05CA06

Brand Names/Synonyms: Seconal (TN); Secobarbital (USP); Novosecobarb; Barbosec; Bipanal; Bipinal sodium; CHEMBANK2949; DEA No. 2315; DEA No. 2316; Evronal; Evronal Sodium; Evrronal; HSDB 3182; Hypotrol; Hyptran; Imesonal; Immenoctal; Immenox; Meballymal; Meballymal sodium; Meballymalum; Pramil; Quinalbarbital; Quinalbarbitone; Quinalbarbitone sodium; Quinalspan; Sebar; Seco 8; Secobarbital; Secobarbital Sodium; Secobarbital [USAN:INN]; Secobarbital suppository dosage form; Secobarbitale [DCIT]; Secobarbitalum [INN-Latin]; Secobarbitone; Seconal; Seconal Sodium; Sedutain; Seotal; Sodium Secobarbital; Sodium Seconal; Sodium quinalbarbitone; Somosal; Synate; Trisomnin; (+/-)-Secobarbital; EINECS 200-982-2; Secobarbital (USP); Seconal (TN)

Dosage Forms: CAPSULE

Absorption: Not Available

Interactions: Interations Barbiturates may decrease the effectiveness of oral contraceptives, certain antibiotics, quinidine, theophylline, corticosteroids, anticoagulants, and beta blockers.



Chemical IUPAC Name: 5-(1-methylbutyl)-5-prop-2-enyl-hexahydropyrimidine-2,4,6-trione

Chemical Formula: C12H18N2O3

Half Life: Not Available

Drug Type: Approved Drug

# Accession No: APRD00497

CAS Registry Number: 76-73-3



Secobarbital News
(When available)


Swiss SECO, IMF to Finance State Securities Sector in Azerbaijan  16 Jan 2006
Baku Today, The International Monetary Fund and Ministry of Economy of Switzerland (SECO) jointly with the National Bank and Ministry of Finance of Azerbaijan are to ...

ASMA Goes Independent, And Launches Ninja 650R Spec Class  16 Jan 2006
RoadracingWorld.com, The Arroyo Seco Motorcyclist Association (ASMA) has broken its year-long affiliation ties with the Championship Cup Series (CCS) and will again be an ...

KEMIRA GROWHOW: Kemira GrowHow - A unified brand name for ...  16 Jan 2006
Webbolt Business News (subscription), As of January 1st, Seco Fertilisants and Kemira GrowHow in France will combine their strengths by adopting the Kemira GrowHow brandname for their fertilizer ...

A Cool Spot Is Now This Cold House  16 Jan 2006
Los Angeles Times, Lummis constructed the sprawling, L-shaped residence at 200 E. Avenue 43 from smooth river rocks he had gathered from the nearby Arroyo Seco. ...

Home » Pulp Factions: Uruguay’s ...  16 Jan 2006
CorpWatch.org, Only five houses remained occupied. Today, Las Flores is known as Pueblo Seco, "Dry Town.". The phenomenon is being repeated throughout the plantation region. ...

Arroyo Seco Medical Group Offers New Year Health Resolutions  Jan 12, 2006
Pasadena Independent, ...worthwhile.�. Arroyo Seco Medical Group (ASMG) has been serving the Greater San Gabriel Valley area for more than a quarter of a century. ...

Seco revises up 2006 Swiss GDP forecast to 1.8 pct, sees job mkt ...  Jan 6, 2006
Forbes ...of 1.7 pct, and is seen rising 1.5 pct in 2007, while the unemployment rate is expected to fall, the state secretariat for economic affairs (SECO) said. ...

Danaher Motion Introduces New SECO AC Servo Fusion Drive  Dec 19, 2005
ARC Advisory Group (press release), Danaher Motion introduces the new SECO FX4000 Fusion all-digital vector drive. These drives combine the functionality of a high ...

Jamestown Streets Closed Due To Structure Fire  Jan 10, 2006
MyMotherLode.com, Main Street is closed at Highway 49, Seco Street is closed and Donovan Street is closed at Seco street. Motorists are advised to avoid the area if possible.

Song choice spot-on  Jan 15, 2006
Pasadena Star-News, ...of us who were inside the stadium a few days after that rainy day didn't notice it, but two people who were walking along the edges of the Arroyo Seco told me ...

Applicants sought for scholarships  Jan 8, 2006
Orlando Sentinel, To qualify for a SECO Youth Scholarship, high school graduates must reside in a home served by SECO (Citrus, Hernando, Lake, Levy, Marion, Pasco and Sumter ...

More and more clinics offer alternative medicine and therapies to ...  Jan 11, 2006
Newstarget.com, Dailynews.com reviews the alternative medical practices of Seco Canyon Animal Clinic, a place where animals experience both homeopathic remedies and ...

Swiss govt raises growth forecast to 1.8 pct  Jan 6, 2006
Xinhua, The State Secretariat for Economic Affairs (Seco) said it was upgrading its previous forecast for 2006 by one tenth of a percentage point. ...

Eye on Coil Annealing  Dec 17, 2005
33Metalproducing SECO/Warwick Corp. ... Each of the newly commissioned tray-type coil annealing furnaces Seco supplied to Alcoa SMP is rated for a 105,000-lb. ...

Monterey County Chardonnay  Jan 5, 2006
San Francisco Chronicle, 2002 Carmel Road Arroyo Seco Chardonnay ($35) Yes, you can have richness, bold flavor and elegance in one wine and this Chardonnay pulls it off. ...

Lake Oroville produces 10.6-pound bass  Jan 12, 2006
Enterprise-Record, ...averages at the refuges last week were as follows: Delevan — 3.15 birds per hunter average (28 geese); Gray Lodge — 0.95 (15 geese); Llano Seco — 2.58 (1 ...

International Finance Corporation and Baku Stock Exchange held ...  Jan 13, 2006
Today.Az, It should be noted that the Azerbaijan Corporate Management Project is carried out by IFC with the financial support from SECO. ...

Weekly Outlook: Swiss Economy Keeps Chugging Ahead  Jan 13, 2006
Daily FX, However, consumer spending is still at risk over the next few months given the low level of consumer confidence, with the SECO consumer climate index remaining ...

Larry Wilson: Of time and the trail  Jan 13, 2006
Pasadena Star-News, ...think it's in the neighborhood interest to renege on the promises, to deny the dream of the contiguous Altadena Crest Trail joining the Arroyo Seco and Eaton ...

Switzerland tweaks up 2006 growth forecast  Jan 6, 2006
Reuters ...and 2007 will broaden and increasingly filter through to the jobs market, but will no longer accelerate," the State Secretariat for Economic Affairs (Seco) said ...

Crowning glory: Pune at home in the world  Dec 29, 2005
Pune Newsline, LIKE many other global manufacturers, SECO Tools AB, the second largest manufacturer for carbide cutting tools in Europe, also announced that India (read Pune ...

Fans queue to get spot at showdown or get ready for kickoff  Jan 4, 2006
Los Angeles Daily News, Writer. So, he stood Tuesday at an intersection in the Arroyo Seco holding a white sign with red letters: "I NEED ROSE BOWL TICKETS.". ...

Game-day parking will be limited  Jan 3, 2006
Pasadena Star-News, PASADENA - This week's torrential rains have saturated Brookside Golf Course in the Arroyo Seco, greatly limiting the number of parking spaces available for ...

Petroglyphs come to 'life'  Jan 4, 2006
Arizona Daily Star, ...without glue. They sell and ship the statues around the nation from their East Side shop, 150 S. Camino Seco. Despite interest from ...

Migration to United States ´dollarizing´ local economy  Dec 31, 2005
El Universal Online, José Luis Luna Palacios, mayor of Arroyo Seco, said that during the months of November, December and January, many migrant workers return home, flooding the ...

Los Angeles Times to Launch 'West' Magazine Feb. 5  Jan 12, 2006
PR Newswire (press release), All of her novels are set in the fictional town of Rio Seco, a loose parallel to her hometown of Riverside, where she is a professor of creative writing at the ...

Bear-ish rematch  Jan 10, 2006
Lincoln Courier, Even after their seco nd stringers allowed Minnesota three touchdowns inside the red zone, the Bears led the league in red zone defensive efficency at 32.5 ...

Ab Ovo. See 7 Days in LA  Jan 11, 2006
LA City Beat, Torranceartmuseum.com. Tue-Sat noon-6. William Lees Judson: Arroyo Seco and Beyond; Plainer: A Contemporary Take on Landscape. Opens Sat. Closes March 11. ...

The globe in a goblet at Mohegan Sun's Winefest  Jan 10, 2006
Providence Journal (subscription), 4 pm Explore the Wines from the Central Coast of California, with an emphasis on the Arroyo Seco and Paso Robles appellations from J Lohr Vineyards. ...

The American god of words  Jan 11, 2006
Axis of Logic, ...one block with two periods– and the Manuel Seco’s Dictionary of doubts and difficulties of the Spanish language writes EE. UU. ...

Gambia groundnut trade  Dec 29, 2005
Daily Observer, However, one aspect need to be properly look into, that is, the calibre of people employed as cashiers or seco managers; because a lot of frodulent activities ...

Man nabbed with heroin, police say  Dec 31, 2005
Santa Fe New Mexican, A man who said he was a Mexican national was arrested with 5 ounces of heroin near Arroyo Seco on Friday, according to state police. ...

San Diego, CA  Dec 19, 2005
San Diego Union Tribune, ...then on. For this exhibit, Jessica Bronson displays on four different screens 2004 footage of a steambed in Arroyo Seco park. Watch ...

Fifty-Foot-Tall Bayer Advanced(TM) Jack and the Rose Stalk Float ...  Dec 27, 2005
PR Newswire (press release), Begins at 11:00 am Eastern Time/8 am Pacific Time (Photo Op: December 27, 2005 - January 1, 2006 Phoenix Decorating's Rosemont Pavilion, 700 Seco Street in ...

Texas-size title: Horns are back on top after 35-year drought  Jan 5, 2006
San Antonio Express (subscription), Five hours before kickoff, the fans had packed the parking lots, firing up their grills and sending a gentle haze wafting over the Arroyo Seco, the old river ...

Game for the ages was all the rage  Jan 5, 2006
San Diego Union Tribune, A track meet. No defense, great offense, incredible plays – and huge gambles. A wild, wonderful, entertaining evening of football in the Arroyo Seco. ...

Disdain led to Trojan's undoing  Jan 5, 2006
Long Beach Press-Telegram, ...an eight-yard touchdown run with 19 second remaining to give his team the Bowl Championship Series title before 93,986 spectators at the old Arroyo Seco stadium ...

Hokies QB proves to be selfish Vick-tim  Jan 6, 2006
ESPN One guy succeeds. One guy fails. It happens every day, not just when ABC has set up 30 cameras in the Arroyo Seco. It happens on the field and off. ...

Ideal Rose Bowl lived up to hype  Jan 5, 2006
Arizona Republic, ...take it," Brown said. Brown's personal triumph came on a night for the ages in the Arroyo Seco. The anticipated shootout between ...

Arrest made in Livermore attempted-rape cases  Dec 20, 2005
San Jose Mercury News, ...attempted to rape. The incident occurred about five months ago on Paseo Laguna Seco and was never reported. Montalvo-Hernandez told ...

News briefs from Southern California  Jan 3, 2006
San Jose Mercury News, ...herb has invaded Whittier Narrows, Eaton Canyon, Whittier Hills, Skyline Trail in the Puente Hills, Monrovia Canyon and the Lower Arroyo Seco, said plant ...

Bahhh'd to the Bone  Jan 5, 2006
Los Angeles Times, At the Ecuadorean El Caserio in Silver Lake, owner William Velasco is finding appreciative new customers for his braised-in-lager seco de chivo, an Andean dish ...

Still the One  Jan 1, 2006
Los Angeles Times, The moon had risen over the Arroyo Seco when the game ended. Sportswriters had to light matches to complete their brilliant accounts. ...

It's Pasadena through rose-colored glasses  Jan 5, 2006
Daily Breeze, But everyone survived and by noon the hovering charcoal-and-meat funk would make the Arroyo Seco resemble what it was long ago, a colorful tribal encampment. ...

Monson: BCS sullies the Rose with false title game  Jan 4, 2006
Salt Lake Tribune, Actually, it's not all that much to look at, the old low-slung structure in the middle of the Arroyo Seco, just up the winding Pasadena Freeway - a real-life ...

Random Rose Bowl callback  Jan 4, 2006
Baseball Toaster, ...championship. As for USC, the 1923 Rose Bowl was the first in a long line of New Year's Day (or near then) appearances in the Arroyo Seco. ...

Cheers and jeers for great fight  Jan 5, 2006
San Bernardino Sun, However, as the game went on, the roar of the USC fans grew louder. But in the end, ''The Eyes of Texas'' resonated throughout the Arroyo Seco. ...

Public Invited to View Rose Float Preparation  Jan 5, 2006
Burbank Weekly, 29 through Dec. 31 from 9 am to 6 pm and Jan. 1 from 11 am to 1 pm at three sites, including Rosemont Pavilion, 700 Seco St. Pasadena ...

Fishing line  Jan 5, 2006
Sacramento Bee, RANCHO SECO LAKE - This is one of the few potential fishable waters in all of the Sacramento area, because it is held at a constant level and doesn"t see a big ...

Art Wilson: The best of two worlds  Jan 6, 2006
Pasadena Star-News, Meant the odd thrill of seeing a hundred thousand people flock to the Arroyo Seco neighborhood in which I grew up - nice when you know how to navigate so it ...

Factions fracture NFL team hopes  Jan 3, 2006
Pasadena Star-News, On the other side are neighborhood activists, Arroyo Seco recreationists, preservationists and some politicians, who have organized to stomp out the last ...

Coyote is 2nd case of rabies in 2006  Jan 7, 2006
Arizona Daily Star, The coyote was spotted near Marshall Elementary School, near East Golf Links Road and South Camino Seco, said Tucson Unified School District spokeswoman ...

Factions' fights fumble football  Jan 4, 2006
San Gabriel Valley Tribune, ...bit more challenging because of some of the actions of the council." On the other side are neighborhood activists, Arroyo Seco recreationists, preservationists ...

Larry Wilson: Witchy weather ahead?  Jan 4, 2006
Pasadena Star-News, The bible of The Craft, as I understand it, is the wind and the rain. I am so down with that. But, pretty please, keep 'em away from the Arroyo Seco tonight?

Hemlock creates havoc in area lowlands  Jan 3, 2006
Whittier Daily News, Center, hemlock can be found in Whittier Narrows, Eaton Canyon, Whittier Hills, Skyline Trail in the Puente Hills, Monrovia Canyon and the Lower Arroyo Seco. ...

News Briefs  Jan 6, 2006
Arcadia Weekly, PASADENA- The city has installed 12 new bike racks at the corner of Arroyo Boulevard and Seco Street, to accommodate up to 24 bike riders attending events at ...

Calypso Signs Letter of Intent to Acquire an Argentine Uranium ...  Jan 4, 2006
CCNMatthews (Communiqués de presse), These four blocks include La Pintada in the Sierra Pintada uranium district, the uranium past-producers Huemul, Arroyo Seco, and Agua Botada in the Malargue ...

Around town  Jan 5, 2006
Marietta Times, The meeting will be held by Southeast Ohio Single Payer Action Network (SEO SPAN) and the Southeast Central Single Payer Action Network (SECO SPAN). ...

Stylish tiles fired in local studio  Jan 2, 2006
Pasadena Star-News, ...a more picturesque site or artistic quarters than the new Batchelder Craft Shop and School of Design on Arroyo Drive overlooking the beauties of the Arroyo Seco ...

IFC Launches Central Asia Leasing Facility’s Swiss-funded ...  Jan 4, 2006
Harold Doan and Associates (press release), The State Secretariat for Economic Affairs (seco) is the Swiss Confederation’s competence center for issues related to economic policy. ...

Environmentalists finally get down to very serious business  Jan 8, 2006
San Francisco Chronicle, Living in Sacramento in the '80s -- when the fate of the Rancho Seco nuclear power plant hung in the balance -- opened my eyes to the power of people at the ...

Fifty-Foot-Tall Bayer Advanced(TM) Jack and the Rose Stalk Float ...  Dec 27, 2005
Yahoo! News (press release) Bayer Advanced Float Decoration Photo Opportunities December 27, 2005 - January 1, 2006 Phoenix Decorating's Rosemont Pavilion, 700 Seco Street in Pasadena ...

Today in History - Dec. 30  Dec 29, 2005
Washington Post, 1 in Flint, Mich. In 1940, California's first freeway, the Arroyo Seco Parkway connecting Los Angeles and Pasadena, was officially opened. ...

A Place for Pets in Disaster Planning  Dec 27, 2005
Los Angeles Times, The walls shook as the group peered through a window and watched a hillside collapse onto two houses across the nearby Arroyo Seco. ...

News briefs from Southern California  Dec 27, 2005
San Jose Mercury News, They all watched as a hillside collapsed onto two houses across the Arroyo Seco. "If you could've heard that hillside coming down it was beyond scary. ...

Livermore man in court on attempted rape charge  Dec 22, 2005
San Jose Mercury News, 15. and confessed, according to a police statement. He also told police there was a fourth victim he tried to rape, on Paseo Laguna Seco about five months ago. ...

Tournament of Roses Countdown  Dec 29, 2005
Valley Sun, The sites included Rosemont Pavilion, 700 Seco St., Pasadena; Brookside Pavilion, southwest of the Rose Bowl, Pasadena; Buena Vista Pavilion, 2144 Buena Vista ...

Thousands Decorate Rose Parade Floats This Week  Dec 26, 2005
NBC4.TV, 27 through Jan. 1 at Rosemont Pavilion, 700 Seco St., Pasadena, directly south of the Rose Bowl, and at the Rose Palace, 835 S. Raymond Ave., Pasadena. ...

Police arrest East Side arsonist  Dec 20, 2005
Arizona Daily Star, ...additional suspects, he said. - Nov. 24 at the Broadway Gardens Apartments, 8880 E. Broadway, near South Camino Seco. - Nov. 25 at the ...

Suspect in 2 of 4 arsons is arrested  Dec 20, 2005
Arizona Daily Star, ...lived at the apartment complex where one of the fires was set on Thanksgiving Day, the Broadway Gardens Apartments, 8880 E. Broadway, near South Camino Seco. ...

GO! Outside  Dec 22, 2005
Monterey County Herald, The loop takes riders through Salinas-Monterey Highway and onto River Road outside of Salinas. From there riders can head south toward the Arroyo Seco area. ...

A review of the year's best and worst outdoors items  Dec 29, 2005
Enterprise-Record, Colusa — 3.16 (4 geese); Gray Lodge — 1.29 (30 geese); Howard Slough — 2.57 (3 geese); Little Dry Creek — 3.13 (7 geese); Llano Seco — 2.47 (no geese ...

Romania: EBRD Grants CET Iasi €20mln Loan  Dec 29, 2005
Reporter.gr, The project was endorsed by SECO, the Swiss State Secretariat for Economic Affairs, which conducted the project's feasibility study and which, at present, aims ...

LIVERMORE 18-YEAR-OLD SUSPECTED IN SEXUAL ASSAULTS  Dec 20, 2005
CBS 5, Investigators say Montalvo-Hernandez also admitted to committing an additional sexual assault on a female in the area of Paseo Laguna Seco about five months ...

This Day in History  Dec 30, 2005
Juneau Empire, 1 in Flint, Mich. • In 1940, California's first freeway, the Arroyo Seco Parkway connecting Los Angeles and Pasadena, was officially opened. ...

Protests dominate 2005  Dec 26, 2005
Trinidad News, ...travel and sabbatical leave. Parents and students of the Brasso Seco RC School protested their school conditions. They complained of ...

Auto Club Rose Parade Advisory: 'Tis the Week after Christmas and ...  Dec 25, 2005
Business Wire (press release), WHERE: Rosemont Pavilion (adjacent to the Rose Bowl), 700 Seco St., Pasadena WHY: The Auto Club sponsors a float in the Tournament of Roses Parade each year as ...

Victory for United  Dec 19, 2005
Louth Today, Captain of Ken... Horncastle 4 Louth 2nds 2 ON a damp, cold winter's afternoon Louth and Horncastle made a seco... Jackson Workwear ...

Sheriff’s log: Wednesday, Dec. 21  Dec 23, 2005
Calaveras Enterprise (subscription), Road Department advised. 9:47 am, Murphys - Abandoned vehicle. Call given to CHP. 10:04 am, Campo Seco - Strange-looking men in a blue sedan in the area. ...

Loving Nuclear Power  Dec 21, 2005
AlterNet, A laundry list of safety, environmental and economic issues resulted in a ballot initiative vote to close the Rancho Seco nuclear power plant in 1989. ...

Project prompts traffic concerns  Dec 30, 2005
Union Democrat, ...between Lime Kiln and Old Wards Ferry. The intersections of Lime Kiln at Highway 108 and at Campo Seco Road would also be improved.

Record breaker at races  Dec 28, 2005
Louth Today, Captain of Ken... Horncastle 4 Louth 2nds 2 ON a damp, cold winter's afternoon Louth and Horncastle made a seco... A RECORD breaking ...

Today In History - December 30th, 2005  Dec 30, 2005
KDKA, Michigan. In 1940, California’s first freeway, the Arroyo Seco Parkway connecting Los Angeles and Pasadena, was officially opened. ...

Calaveras School Board Appoints President  Dec 22, 2005
MyMotherLode.com, ...of Education. Looper represents the communities of Wallace, Burson, Campo Seco, Paloma, Mokelumne Hill, and San Andreas. The board ...

News briefs from Southern California  Dec 22, 2005
San Luis Obispo Tribune, Pat Griffith, president of the Arroyo Seco Neighborhood Council, said residents of her Mount Washington neighborhood were caught off guard by the signs. ...

Fitch Rates SMUDFA's Consumnes Project Revs 'BBB'; Stable Outlook  Dec 20, 2005
Business Wire (press release), ...is a 500 MW, combined cycle, natural gas-fired generating plant being constructed 0.5 miles from the site of SMUD's existing Rancho Seco nuclear facility ...

Taos Has Best Skiing in New Mexico  Dec 27, 2005
OUTDOORNEWSWIRE, The doors open at 7pm and the show starts at 8 pm Tickets for the show are available at the Martini Tree Bar or Lena's in Arroyo Seco. ...

BICC ‘05/06 – Round 4 Results  Dec 19, 2005
British Mountaineering Council, In V1 Female Jill Whittaker, Katy’s mum, couldn’t quite match her daughter’s performance, finishing second to Joanna Mitchell. V1 Male went to Luis Seco. ...

Landfill contract leads to lawsuit  Dec 20, 2005
Union Democrat, The county awarded Ferma a roughly $4.47 million contract to permanently seal the former landfill off Campo Seco Road in April 2004. ...

The Annexation of La Cañada Flintridge  Dec 28, 2005
Valley Sun, Pasadena wanted all of Flintridge and a section of La Cañada running east of Alta Canyada Road to the Arroyo Seco, north of Foothill Boulevard. ...

The land nobody wants  Dec 21, 2005
Stockton Record, ...proving to be ... CAMPO SECO -- Realtor Paula Davis put on her ranch boots this week to walk a 157-acre problem property. She crunched ...

AMP to begin megaport project bidding process Jan 3  Dec 29, 2005
BNamericas, The new port terminal will be located on the west side of the Pacific entrance of the Panama Canal, in the Palo Seco/Farfán area, close to the former US air ...

Christmas tree pickup established at 3 parks  Dec 27, 2005
Beaumont Enterprise, Trees stripped of their stands, decorations and any plastics can be left at Rogers Park at Dowlen and Gladys; Sprott Park at Usan and Virginia; and Magnolia ...

Clemson 52, Winthrop 51  Dec 20, 2005
Gainesville Sun, ...usan Yenser's putback in the final second gave Clemson a 52-51 win over Winthrop on Tuesday night. The Lady Tigers (5-6) led 48-37 ...


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