Pharmacology: Scopolamine is a muscarinic antagonist structurally similar to the neurotransmitter acetylcholine and acts by blocking the muscarinic acetylcholine receptors and is thus classified as an anticholinergic. Scopolamine has many uses including the prevention of motion sickness. It is not clear how Scopolamine prevents nausea and vomiting due to motion sickness. The vestibular part of the ear is very important for balance. When a person becomes disoriented due to motion, the vestibule sends a signal through nerves to the vomiting center in the brain, and vomiting occurs. Acetylcholine is a chemical that nerves use to transmit messages to each other. It is believe that Scopolamine prevents communication between the nerves of the vestibule and the vomiting center in the brain by blocking the action of acetylcholine. Scopolamine also may work directly on the vomiting center. Scopolamine must be taken before the onset of motion sickness to be effective.
Mechanism Of Action: Scopolamine acts by interfering with the transmission of nerve impulses by acetylcholine in the parasympathetic nervous system (specifically the vomiting center).
Interactions:
DrugBank: Interactions for Scopolamine
Interactions for Scopolamine:
The absorption of oral medications may be decreased during the concurrent use of scopolamine because of decreased
gastric motility and delayed gastric emptying.
Scopolamine should be used with care in patients taking other drugs that are capable of causing CNS effects such
as sedatives, tranquilizers, or alcohol. Special attention should be paid to potential interactions with drugs having
anticholinergic properties; e.g., other belladonna alkaloids, antihistamines (including meclizine), tricyclic
antidepressants, and muscle relaxants.
Laboratory Test Interactions
Scopolamine will interfere with the gastric secretion test.
Chemical IUPAC Name: Not Available
Chemical Formula: C17H21NO4
Half Life: Not Available
Drug Type: Approved Drug
# Accession No: APRD00616
CAS Registry Number: 6533-68-2
Scopolamine News (When available)
Hyundai to Build Integrated Steel Mill16 Jan 2006 Korea Times, Hyundai Motor Group also owns steelmaking units Hyundai Hysco and BNG Steel, which have an annual capacity of 4.5 million tons and 300,000 tons, respectively. ...
Higher Education is meeting the challenges of FOI Act says surveyJan 8, 2006 PublicTechnology.net, The survey, a joint initiative by JISC (Joint Information Systems Committee), Universities UK and SCOP (the Standing Conference of Principals), show that the ...
How Federated Databases Benefit Bioinformatics ResearchJan 10, 2006 B-EYE-Network, ...“Find all structural homologs of putative N-acetyltransferase SR144 in B. subtillus in SCOP family Acyl-CoA N-acetyltransferase.�. ...
Universities 'coping' with freedom of information demandsJan 9, 2006 eGov monitor, The survey by the Joint Information Systems Committee, Universities UK and the Standing Conference on Principles (SCOP) was conducted to establish how the ...
Former chief scientist Shuki Gleitman joins Ascend fundJan 12, 2006 Globes, ...(Nasdaq:SCOP); an IPO by Topspin Medical Inc. (TASE:TOPMD); and Shellcase sale of its intellectual property to Tessera Technologies Inc. (Nasdaq:TSRA). ...
Remembering the top stories of '05Jan 4, 2006 Sewickley Herald, Brandon Duckworth, Christine Jehle and Sereen Askari, along with Sensei Dustin Baldis, chief instructor, all took part in the Pan American Championships in ...
The North American Menopause Society Highlights from Jan/FebJan 12, 2006 PharmaLive.com (press release), In this secondary analysis of data from the UltraLow-Dose Transderm Estrogen Assessment trial (ULTRA), women who were randomized to receive either unopposed ...
CORPORATE LINKSJan 8, 2006 Saigon Times Daily, ...* Mekophar in HCMC last year produced nearly 400 tons of material for Ampicilin and Amoxicilin trihydrate. Currently, the company ...
Home
Copyright phasechange.org 2006.
All Rights Reserved.
