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Rescinnamine
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DRUG INFO
Rescinnamine
Drug Name:
Rescinnamine
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Indication: For the treatment of hypertension
Pharmacology: Used to treat hypertension. Rescinnamine inhibits angiotensin-converting enzyme. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. Angiotensin II also stimulates aldosterone secretion by the adrenal cortex.
Mechanism Of Action: Binds to and inhibits the angiotensin converting enzyme. Rescinnamine competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in decreased plasma angiotensin II. As angiotensin II is a vasoconstrictor and a negative-feedback mediator for renin activity, lower concentrations result in a decrease in blood pressure and stimulation of baroreceptor reflex mechanisms, which leads to decreased vasopressor activity and to decreased aldosterone secretion.
Drug Category: Antihypertensive Agents; ATC:C02AA01
Brand Names/Synonyms: Anapral; Anaprel; Apolon; Apoterin; Apoterin S; Cartric; Cinamine; Cinatabs; Cinnaloid; Cinnasil; Methyl Trimethoxycinnamoylreserpate; Moderil; Normorescina; Paresinan; RESCINNAMINE; Raupyrol; Raurescin; Raurescine; Recinnamine; Recitensina; Rescaloid; Rescamin; Rescidan; Rescin; Rescinnamin; Rescinpal; Rescisan; Rescitens; Resealoid; Reserpinene; Reserpinin; Reserpinine; Resipal; Reskinnamin; Rozex; Scinnamina; Tenamine; Trimethoxycinnamoyl Methyl Reserpate; Tsuruselpi S; Tuareg
Dosage Forms: Not Available
Absorption: Not Available
Interactions: Not Available
Chemical IUPAC Name: Not Available
Chemical Formula: C35H42N2O9
Half Life: Not Available
Drug Type: Approved Drug
# Accession No: APRD00112
CAS Registry Number: 24815-24-5
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