Pioglitazone resources


DRUG INFO
Pioglitazone

Drug Name: Pioglitazone

Indication: Treatment of Type II diabetes mellitus



Pharmacology: Pioglitazone, a member of the drug group known as the thiazolidinediones or "insulin sensitizers", is not chemically or functionally related to the alpha-glucosidase inhibitors, the biguanides, or the sulfonylureas. Pioglitazone targets insulin resistance and, hence, is used alone or in combination with insulin, metformin, or asulfonylurea as an antidiabetic agent.

Mechanism Of Action: Pioglitazone acts as an agonist at peroxisome proliferator activated receptors (PPAR) in target tissues for insulin action such as adipose tissue, skeletal muscle, and liver. Activation of PPAR-gamma receptors regulates the transcription of insulin-responsive genes involved in the control of glucose production, transport, and utilization. In this way, pioglitazone enhances tissue sensitivity to insulin.

Drug Category: Hypoglycemic Agents; Thazolidinediones; ATC:A10BG03

Brand Names/Synonyms: AD-4833; Actos; Actost; CHEMBANK3906; Pioglitazona [Inn-Spanish]; Pioglitazone; Pioglitazone Hydrochloride; Pioglitazone [Ban:Inn]; Pioglitazonum [Inn-Latin]

Dosage Forms: Oral tablets

Absorption: Following oral administration, in the fasting state, pioglitazone is first measurable in serum within 30 minutes, with peak concentrations observed within 2 hours. Food slightly delays the time to peak serum concentration to 3 to 4 hours, but does not alter the extent of absorption.

Interactions: DrugBank: Interactions for Pioglitazone

Interactions for Pioglitazone:


In vivo drug-drug interaction studies have suggested that pioglitazone may be a weak inducer of CYP 450 isoform 3A4 substrate.





Chemical IUPAC Name: 5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]thiazolidine-2,4-dione

Chemical Formula: C19H20N2O3S

Half Life: 3-7 hours

Drug Type: Approved Drug

# Accession No: APRD00653

CAS Registry Number: 111025-46-8



Pioglitazone News
(When available)


Pharma cos may record modest growth in Q3  15 Jan 2006
Economic Times, 7-8 are currently in litigation. The rulings for Actos, Valtrex, Fiomax, Provigil and Tricor are expected in the coming months.

Heart disease's link to diabetes  Jan 11, 2006
International Herald Tribune, Thiazolidinediones, like Actos and Avandia, used to increase insulin sensitivity in diabetes, act by regulating glucose and insulin. ...

Glaxo's Diabetes Drug Tied to Eye Risk, US FDA Says (Update2)  Jan 5, 2006
Bloomberg European regulators last month also said they are reviewing macular edema reports in people using Avandia and Takeda Pharmaceutical Co.'s similar Actos drug. ...

Drug warning seen minor setback for Glaxo  Jan 6, 2006
Scotsman, ...last month, when its experts announced they were reviewing the safety of both Avandia and Takeda Pharmaceutical's <4502.T> similar anti-diabetes drug Actos. ...

Drug warning seen minor setback for Glaxo  Jan 6, 2006
Reuters.uk, ...experts announced they were reviewing the safety of both Avandia and Takeda Pharmaceutical's (4502.T: Quote, Profile, Research) similar anti-diabetes drug Actos ...

Concord Monitor and New Hampshire Patriot  Jan 9, 2006
Concord Monitor, The pharmacy could not find me in the system! Let's hope they can find me for my next prescription for Actos, which is $188 for 30 pills. ...

Advair may get a stronger warning label  Jan 11, 2006
Daily Press, ...our medicines. I take Lipitor for cholesterol, Norvasc, Altace and Toprol-XL for high blood pressure and Actos for diabetes. My ...

Europe studies eye problem link to diabetes drugs  Dec 15, 2005
NewKerala.com, ...episodes of macular oedema, or swelling of the back of the eye, had been reported with GlaxoSmithKline Plc's Avandia and Takeda Pharmaceutical Co Ltd's Actos. ...

The People's Pharmacy  Jan 1, 2006
Seattle Times, Q: My job was outsourced last year, and I lost my health coverage. I take Lipitor, Norvasc, Altace, Toprol-XL and Actos. My wife takes Fosamax and Aciphex. ...

Indian drug firms to continue with strategy  Dec 19, 2005
International Herald Tribune, ...patents on brands like GlaxoSmithKline's herpes drug Valtrex; AstraZeneca's anti-ulcer drug Nexium; and Takeda Pharmaceutical's insulin sensitizer Actos. ...

Indian Drug Maker Says It Will Keep Attacking Patents Despite ...  Dec 19, 2005
New York Times, ...the patents on brands like Valtrex, GlaxoSmithKline's herpes drug; Nexium, AstraZeneca's anti-ulcer and heartburn medicine; and Actos, Takeda Pharmaceutical's ...

Glaxo, IMI, LSE, Persimmon, SMG: UK, Irish Equity Preview  Dec 15, 2005
Bloomberg GlaxoSmithKline Plc (GSK LN): The diabetes drug Avandia, made by Europe's largest drugmaker, and Takeda Pharmaceutical Co.'s Actos will be reviewed by European ...

Around Asia's markets: Japanese face side effects of drug costs  Dec 15, 2005
International Herald Tribune, Shionogi has risen 20 percent. Worldwide sales of Takeda's Actos, a diabetes treatment, rose 20 percent in the six months that ended Sept. ...

European Chip Stocks, Infineon May Advance; Novartis May Drop  Dec 15, 2005
Bloomberg GlaxoSmithKline Plc's Avandia and Takeda Pharmaceutical Co.'s Actos will be reviewed by European health regulators after the two diabetes treatments were ...

Glitazone link to macular oedema explored  Dec 15, 2005
Reuters ...received reports of cases of macular oedema in patients taking GlaxoSmithKline's Avandia/Avandamet (rosiglitazone) and Takeda and Lilly's Actos (pioglitazone). ...

New US envoy lays out his vision for a democratic Cuba  Dec 13, 2005
Sun-Sentinel.com, On Monday, he said the actos de repudio, or acts of repudiation in which government supporters harass opposition figures, continue and are another sign that ...

GUAM: Ice Epidemic Sweeps Guam  16 Jan 2006
Pacific Magazine, Pacific Daily News reports that since November, Guam Customs and Quarantine has seized more than $2 million worth of methamphetamine hydrochloride, the drug ...

Truck overturns, spilling hydrochloride, forcing some evacuations  Dec 15, 2005
Times Daily, Some Daphne businesses near the Interstate 10 exit were temporarily evacuated Thursday after a truck overturned, spilling hydrochloride. ...

Truck overturns, spills hydrochloride  Dec 16, 2005
Montgomery Advertiser, DAPHNE -- Some Daphne businesses near the Interstate 10 exit were evacuated temporarily Thursday after a truck overturned, spilling hydrochloride. ...

Eisai Receives Confirmation that Aricept (donepezil hydrochloride) ...  Dec 27, 2005
Japan Corporate News (press release), Tokyo, Japan, Dec 27, 2005 - (JCN Newswire) - Eisai Co., Ltd. (TSE: 4523) announced that its UK subsidiary, Eisai Ltd., has received ...

Eisai Receives Confirmation that Aricept (donepezil hydrochloride) ...  Dec 27, 2005
Asia Corporate News Network (press release), ...(via ACN Newswire) - Tokyo, Japan, Dec 27, 2005 - (JCN Newswire) - Eisai Co., Ltd. (TSE: 4523) announced that its UK subsidiary, Eisai ...

PLIVA Announces Tentative Approval for Sertraline Hydrochloride ...  Dec 23, 2005
Biotech Intelligence (press release), Food and Drug Administration ("FDA") has granted tentative approval for its Abbreviated New Drug Application ("ANDA") for Sertraline Hydrochloride tablets, 25 ...

Eisai Receives Confirmation That Aricept (donepezil Hydrochloride) ...  Dec 27, 2005
PharmaLive.com (press release), TOKYO, Dec. 27, 2005-Eisai Co., Ltd. (Headquarters: Tokyo, President: Haruo Naito) announced that its UK subsidiary, Eisai Ltd. ...

Black-market bird flu drug seized in raids  Jan 14, 2006
The Sunday Times, One British firm was last week offering on its website a cheaper, less effective antiviral drug called Amantadine Hydrochloride and calling it Tamiflu. ...

2 Maranaos face drug transport rap  Jan 13, 2006
Sun.Star, ...shabu. The materials taken from the suspects were tested positive for Methamphetamine Hydrochloride or commonly known as shabu. ...

Eisai Receives Confirmation that Aricept (donepezil hydrochloride) ...  Dec 27, 2005
TMCnet ...(Comtex Business)Tokyo, Japan, Dec 27, 2005 (JCN Newswire via COMTEX) --Eisai Co., Ltd. (TSE: 4523) announced that its UK subsidiary ...

Aricept (donepezil Hydrochloride), Orodispersible Tablet ...  Dec 29, 2005
Medical News Today (press release), Tokyo, Japan, (JCN Newswire) - Eisai Co., Ltd (TSE: 4523) announced that its UK subsidiary, Eisai Ltd, has received notification of the completion of the ...

Seized jeans impregnated with cocaine  Jan 13, 2006
Irish Medical News, ...was detained at Dublin airport on suspicion of smuggling illegal substances, and was later found to have been carrying around 865g of cocaine hydrochloride. ...

New Study Suggests Cymbalta (Duloxetine Hydrochloride) Reduced ...  Dec 13, 2005
DG News INDIANAPOLIS, IN -- December 13, 2005 -- Cymbalta(R) (duloxetine hydrochloride) reduced symptoms of depression at least as fast as Lexapro(R) (escitalopram) by ...

Do the math: Same drugs, lower price  Jan 15, 2006
Boston Globe, For example, Metformin hydrochloride, a diabetes drug, cost $18 at Johnson compared with $88.19 at Walgreens and $85.59 at CVS at the same quantity and ...

Genzyme Reports 22 Percent Increase in Fourth-Quarter Revenue  Jan 9, 2006
MSN Money Fourth-quarter revenue for Renagel(R) (sevelamer hydrochloride), a phosphate binder for patients with end-stage kidney disease on hemodialysis, grew 12 percent ...

Sepracor Receives Notice of Second Abbreviated New Drug ...  Jan 12, 2006
Business Wire (press release), FDA) has received an abbreviated new drug application (ANDA) from Dey, LP for a generic version of levalbuterol hydrochloride inhalation solution. ...

McDermott´s 2005 Top 10 Life Science Decisions  Jan 10, 2006
Mondaq News Alerts, ...to the Hatch-Waxman Amendments to the Federal Food, Drug and Cosmetic Act, seeking approval to market its generic version of the drug sertraline hydrochloride. ...

Sepracor to defend Xopenex  Jan 12, 2006
MetroWest Daily News, ...maker Merck KGaA, had filed a generic drug application with the Food and Drug Administration for a version of inhalable levalbuterol hydrochloride, the active ...

Cops, NBI raid idle ‘shabu lab’  Jan 13, 2006
Sun.Star, ...an empty warehouse in Barangay Pulpogan, Consolacion, Cebu were equipment units essential to the manufacture of methamphetamine hydrochloride, commonly known ...

Arch Chemicals Reports that Studies Confirm that Vantocil(TM) ...  Jan 13, 2006
Business Wire (press release), ...environments is impractical. VANTOCIL(TM) is based on the active ingredient poly (hexamethylenebiguanide) hydrochloride (PHMB). The PHMB ...

Local news  Jan 10, 2006
Pacific Daily News, In a plea agreement, Cole pleaded guilty to conspiracy to distribute more than 92 grams of methamphetamine hydrochloride from Mexico to California to Hawaii to ...

City Councilman resigns  Jan 12, 2006
Myrtle Beach Sun News, ...and July 5. Those drugs included hydrocodone, marijuana, OxyContin, Zyrtec 10, buspirone hydrochloride and ranitidine. He also is ...

Sepracor Receives Notice of Second Abbreviated New Drug ...  Jan 12, 2006
Finanzen.net, Administration (FDA) hasreceived an abbreviated new drug application (ANDA) from Dey, LP fora generic version of levalbuterol hydrochloride inhalation solution ...

Protein Design Labs Becomes PDL BioPharma  Jan 9, 2006
MSN Money The company now markets Cardene(R) IV (nicardipine hydrochloride) for short-term treatment of hypertension when oral therapy is not feasible or desirable ...

Speaking the truth on prostitution  Jan 11, 2006
Taipei Times, ...do to me unless I was high," she said of her days as a sex worker, when she masked her pain through marijuana and methamphetamine hydrochloride, a stimulant ...

City police plans to clamp down on 'date rape' drugs  Jan 10, 2006
Economic Times, The drugs — lorezapam, ketamine hydrochloride, alprazolam, gamma hydroxybutyric acid and flunitrazepam — are essentially sleeping pills or tranquilizers. ...

Cephalon, Inc. Announces Agreement with Mylan Pharmaceuticals Inc. ...  Jan 10, 2006
PharmaLive.com (press release), The company currently markets four proprietary products in the United States: PROVIGIL, GABITRIL(R) (tiagabine hydrochloride), ACTIQ(R) (oral transmucosal ...

NitroMed Promotes Michael Sabolinski, MD to the Position of Chief ...  Jan 6, 2006
Genetic Engineering News, ...and participate in certain key decision making processes relative to the development of BiDil(R) (isosorbide dinitrate/hydralazine hydrochloride) outside of ...

Memantine (Namenda) Found Effective for Advanced Alzheimer's ...  Jan 10, 2006
SeniorJournal.com, ..."Although memantine hydrochloride helps treat the symptoms of Alzheimer’s disease, there is no evidence that it modifies the underlying pathology of the ...

CTMA OKs supplier switch  Jan 12, 2006
Daily American Online (subscription), Chemstream, owned by Mike Kaufman of Boswell, will now provide the plant with sodium hydrochloride (chlorine) and phosphate, replacing SAL Chemical Co. ...

Customs officer recounts raid at hearing in ice case  Jan 9, 2006
Pacific Daily News, ...afternoon as attorneys grilled Guam Customs and Quarantine officers about the raid of a hotel room allegedly being used to produce methamphetamine hydrochloride ...

Simply Fit  Jan 12, 2006
Mercury-Register, ...after a meal. This formula contains betaine hydrochloride which starts the first phase of digestion in the stomach. It also provides ...

New hope for smokers  Dec 23, 2005
USA Weekend ...up. And there are non-nicotine methods, including behavior modification and the prescription drug bupropion hydrochloride (Zyban). ...

GENZYME: Pipeline Highlights  Jan 12, 2006
Webbolt Business News (subscription), Enrollment has been completed in a trial evaluating the product's equivalence to sevelamer hydrochloride for patients with end-stage renal disease. ...

2100 units but no ‘checks’  Jan 5, 2006
Hindustan Times, Ayurvedic officials received another complain that ephedrine hydrochloride was being mixed in ‘Som churn’ again the officials prefer to look the other way. ...

Date rape drugs available freely  Jan 1, 2006
Times of India, There are at least three date rape drugs known internationally—GHB (gamma hydroxybutyric acid), Rohypnol (flunitrazepam) and Ketamine (ketamine hydrochloride ...

Andrx Files Patent Infringement Suit Against GlaxoSmithKline Over ...  Dec 21, 2005
Patent Baristas, ...that GlaxoSmithKline's 150 milligram dose of extended-release Wellbutrin violates its patent covering a once-a-day form of bupropion hydrochloride, the active ...

Company Says FDA Has OK'd its Sodium Treatment Drug  Dec 31, 2005
HealthCentral.com Astellas Pharma US Inc. said it would sell the drug, conivaptan hydrochloride, under the brand name Vaprisol, the Associated Press said. ...

Depomed Announces Positive Results of Phase II Clinical Trial for ...  Jan 4, 2006
PharmaLive.com (press release), Proquin(R) XR (ciprofloxacin hydrochloride) once daily, extended-release tablets have been approved by the FDA for the treatment of uncomplicated urinary tract ...

NitroMed to Present at 24th Annual JPMorgan Healthcare Conference  Jan 4, 2006
Genetic Engineering News, Massachusetts is a research-based emerging pharmaceutical company and the maker of BiDil(R) (isosorbide dinitrate/hydralazine hydrochloride), an orally ...

Trader gets life for selling shabu  Jan 3, 2006
The Mindanao Daily Mirror, A 24-year-old compact disc vendor was sentenced to life imprisonment for selling eight small sachets of shabu (methamphe-tamine hydrochloride) at a pool resort ...

Amicus Therapeutics to Present at JPMorgan Healthcare Conference  Jan 4, 2006
PR Newswire (press release), The company's lead compound Amigal(TM) (migalastat hydrochloride) is in Phase ll clinical trials for Fabry disease and the company plans to initiate clinical ...

Evidence questioned in ice case  Jan 5, 2006
Pacific Daily News, Justin Keith Guerrero and Renea Dorleen Cruz-Taitano, who were arrested on charges of possession of methamphetamine hydrochloride as part of the September ice ...

Barrier Therapeutics Appoints Edward L. Erickson to Its Board of ...  Jan 3, 2006
Market Wire (press release) US and Canada for the treatment of solar lentigines, a common condition also known as "age spots," and markets VANIQA®, (eflornithine hydrochloride) Cream 13.9 ...

Major new medication promising for black heart patients  Jan 2, 2006
Fort Lauderdale Sun Sentinel, The two drugs -- hydralazine hydrochloride and isosorbide dinitrate -- increase nitric oxide that relaxes and dilates blood vessels to improve blood flow. ...

Advisory - Health Canada advises consumers not to use Kaizen ...  Dec 28, 2005
Canada NewsWire (press release), Kaizen Ephedrine HCL tablets contain ephedrine hydrochloride, which is authorized by Health Canada only for use as a nasal decongestant in over-the- counter ...

Pharmacogenomic Test Predicts Chemo Toxicity 1/5/06  Jan 5, 2006
Bioscience Technology, ...test that identifies individuals at high risk of adverse reactions to the colon cancer chemotherapy drug irinotecan hydrochloride (Camptosar) is now being ...

Caraco Pharmaceutical Laboratories, Ltd. Announces FDA Final ...  Dec 19, 2005
PR Newswire (press release), Drug Administration (FDA) have granted final approval for the Company's Abbreviated New Drug Application (ANDA) for Tramadol Hydrochloride with Acetaminophen ...

OxyContin(R) Dismissals and Withdrawals Exceed 400  Jan 5, 2006
Yahoo! News (press release) OxyContin Tablets are a controlled-release oral formulation of oxycodone hydrochloride indicated for the management of moderate to severe pain when a continuous ...

Amicus Therapeutics Appoints David J. Lockhart Chief Scientific ...  Jan 6, 2006
Yahoo! News (press release) The company's lead compound Amigal(TM) (migalastat hydrochloride) is in Phase II clinical trials for Fabry disease and the company plans to initiate clinical ...

Health in 2005: the Efforts, the Results  Jan 6, 2006
AllAfrica.com, During the conference, it was said a new drug, chlorproguannil hydrochloride-clapsone-artesunate, CDA, had been discovered to be an effective cure for ...

Two indicted for "ice" distribution  Jan 4, 2006
KUAM.com, Wednesday. Pauline Marie Castro and John Junior Cruz were charged with distribution of methampethamine hydrochloride. According ...

Ukraine river contaminated with chlorine  Dec 22, 2005
ITAR-TASS, ...mountainous Sivka River, a tributary of the Dniester River in the Ivano-Frankovsk region, has been contaminated with calcium hydrochloride, substance identical ...

Moldova says no warning from Ukraine over river contamination  Dec 22, 2005
ITAR-TASS, Moldova about the contamination of Ukraine’s mountainous Sivka River, a tributary of the Dniester River, with calcium hydrochloride, substance identical to ...

Antibiotic approved for honeybee disease  Jan 6, 2006
Capital Press (subscription), Before tylosin tartrate, only one other antibiotic, oxytetracycline hydrochloride (Terramycin), was available for use against American foulbrood. ...

Data Show Cost-Effectiveness of NitroMed's BiDil Through Reduced ...  Dec 13, 2005
PharmaLive.com (press release), ...with Heart Failure" published today in Circulation: Journal of the American Heart Association, BiDil(R) (isosorbide dinitrate/hydralazine hydrochloride) is a ...

Aurobindo’s drug gets final nod from USFDA  Dec 14, 2005
Daily News & Analysis, With this approval, coupled with the earlier tentative nod for its Sertraline Hydrochloride, dubbed as the bio-equivalent of Pfizer’s anti-depressant Zoloft ...

Targacept and AstraZeneca Announce Global License and Research ...  Dec 31, 2005
Drug Newswire (press release), Targacept has a marketed product, Inversine(R) (mecamylamine hydrochloride), product candidates in clinical development for cognitive impairment, including ...

FDA Approves Astellas' Vaprisol® For Treatment Of Euvolemic ...  Jan 1, 2006
Medical News Today (press release), ...that the US Food and Drug Administration (FDA) has approved VAPRISOL® (investigational name: YM087, generic name: conivaptan hydrochloride injection), an ...

NAACP and NitroMed Announce Partnership to Narrow Disparities in ...  Dec 14, 2005
PharmaLive.com (press release), ...an aldosterone antagonist. BiDil is a fixed-dose combination of isosorbide dinitrate and hydralazine hydrochloride. While the exact ...

State to seize 'drug farm'  Dec 22, 2005
News24, Nkosi said there was sufficient ephedrine hydrochloride, synthesized product and "tik" crystals on the farm premises to produce approximately 45 kg of "tik ...

Company says FDA OKs sodium level drug  Dec 30, 2005
Seattle Post Intelligencer ...manufacturer said Friday. Astellas Pharma US Inc. said it would market the drug, conivaptan hydrochloride, as Vaprisol. It will be ...

DRL gets tentative US nod for antidepressan  Dec 29, 2005
Sify, ...on Thursday received tentative approval from the US Food and Drug Administration for antidepressant drug sertraline hydrochloride. |Read more Finance news.|. ...

Sensex gains 41 pts @ 10:50 hrs  Dec 29, 2005
Sify, ...cent to Rs 965.90 after it received on Thursday tentative approval from the US Food and Drug Administration for anti-depressant drug sertraline hydrochloride. ...

Indian shares climb, Colombo also up  Dec 30, 2005
Daily Times, ...percent to Rs 978.50 after it received on Thursday tentative approval from the US Food and Drug Administration for anti-depressant drug sertraline hydrochloride ...

FDA OKs Caraco generic brand of Ultracet  Dec 19, 2005
BusinessWeek ...less. The therapy combines a product called tramadol hydrochloride with acetaminophen, also known by its Tylenol brand name. Caraco ...

'Tik' farm seized  Dec 22, 2005
News24, Nkosi said at the time there was enough ephedrine hydrochloride on the premises to produce approximately 45kg of "tik" with a value of R11.3m. ...

Dr Reddy's gets tentative nod for antidepressant  Dec 30, 2005
Economic Times, ...on Thursday received tentative approval from the US Food and Drug Administration for antidepressant drug sertraline hydrochloride. ...

Metro/State business briefs  Dec 20, 2005
DetNews.com, Monday that the US Food and Drug Administration has granted final approval for the company's new drug application for Tramadol Hydrochloride with Acetaminophen ...

FDA Issues Approvable Letter for VIVITROL(TM) (Formerly VIVITREX(R ...  Dec 28, 2005
Business Wire (press release), The company currently markets four proprietary products in the United States: PROVIGIL(R) (modafinil) (C-IV), GABITRIL(R) (tiagabine hydrochloride), ACTIQ(R ...

Lilly Resolves Investigation of Its Evista Marketing and ...  Dec 21, 2005
PR Newswire (press release), ...forward-looking statements. Evista(R) (raloxifene hydrochloride, Lilly) (Logo: http://www.newscom.com/cgi-bin/prnh/20031219/LLYLOGO ).

Targacept, AstraZeneca Enter TC-1734 Deal For Up To $300M  Dec 28, 2005
BioWorld Online (subscription), Targacept has one marketed product, Inversine (mecamylamine hydrochloride), which was acquired from Sunnyvale, Calif.-based Layton Bioscience Inc. ...

Bio-IT Briefs  Dec 22, 2005
Bio-IT World, ...its laboratory to determine through genetic screening which patients are likely to have a serious adverse reaction to irinotecan hydrochloride (Camptosar), a ...

State to Confiscate 'Tik' Farm  Dec 22, 2005
AllAfrica.com, Mr Nkosi said there was sufficient ephedrine hydrochloride, synthesized product and "tik" crystals on the premises to produce approximately 45kg of "tik" with ...

Depomed, Biovail Revise Partnership Agreement for Development ...  Dec 13, 2005
CCNMatthews (press release), ...agreement for the development and commercialization of Glumetza(tm), a once-daily, extended-release formulation of metformin hydrochloride (HCl) for the ...

BioCryst Initiates Intravenous Phase I/II Clinical Trial of ...  Dec 22, 2005
PR Newswire (press release), ...(NASDAQ: BCRX) today announced that it has initiated a Phase I/II clinical trial of Fodosine(TM) (forodesine hydrochloride), the company's lead anti-cancer ...

America's Weight Problem - Where Is The Pharmaceutical Industry?  Dec 19, 2005
Medical News Today (press release), Meridia® (sibutramine hydrochloride monohydrate) from Knoll Pharmaceuticals, one of two weight loss Rx drugs that have been approved by the Food and Drug ...

MGI PHARMA to Present at the JPMorgan Healthcare Conference  Dec 21, 2005
Genetic Engineering News, MGI PHARMA markets Aloxi(R) (palonosetron hydrochloride) injection and Gliadel(R) Wafer (polifeprosan 20 with carmustine implant) in the United States. ...

Woman gets 46 months in ice case  Dec 14, 2005
Pacific Daily News, Deanna Morales was sentenced in the US District Court of Guam yesterday after pleading guilty to possession of methamphetamine hydrochloride with intent to ...

Pyrotechnics Suspended in Guatemala  Dec 30, 2005
Prensa Latina, The fact shocked Guatemalans and drove different sectors to request the prohibition of the petards made of hydrochloride of potassium and fulminating mercury. ...

Altair Nanotechnologies Expands Intellectual Property Portfolio ...  Dec 19, 2005
Market Wire (press release) Altairnano products: -- Titanium dioxide pigment, as embodied in Altairnano's proprietary Hydrochloride Pigment process (AHP). -- Nano ...

Termination of firefighter reversed  Dec 21, 2005
KUAM.com, ...reversed. John Troy Santos was charged with attempted possession with the intent to distribute methamphetamine hydrochloride. While ...

Cops bust shabu lab in Angeles City  Dec 20, 2005
Sun.Star, ...scraped off from strainer funnels, drying pans, and other handling equipment by Babor's team tested positive of methamphetamine hydrochloride during an on-the ...

U Chicago researchers license pharmacogenomics test for patients ...  Dec 21, 2005
EurekAlert (press release), ...have licensed a genetic test that determines which patients are likely to have a serious adverse reaction to irinotecan hydrochloride (Camptosar®), a key ...

A combined effort to end meth  Dec 30, 2005
Daily Home Online, ...through state and federal grants, got retailers from Wal-Mart to Dollar General involved in tracking thefts of pseudoephedrine hydrochloride, ephedrine and ...

Cephalon, Inc. Completes Acquisition of Zeneus Holdings Limited  Dec 22, 2005
Yahoo! News (press release) ...company currently markets four proprietary products in the United States: PROVIGIL® (modafinil) [C-IV], GABITRIL® (tiagabine hydrochloride), ACTIQ® (oral ...

Cephalon, Inc. Completes Acquisition of Zeneus Holdings Limited  Dec 22, 2005
Boursorama, The company currently markets four proprietary products in the United States: PROVIGIL(R) (modafinil) [C-IV], GABITRIL(R) (tiagabine hydrochloride), ACTIQ(R ...

Altair Nanotechnologies and Western Oil Sands Extend Phase One of ...  Dec 29, 2005
Market Wire (press release) Altairnano entered into a technology licensing agreement with Western Oil Sands Inc., in January 2004 to use the Altairnano Hydrochloride Pigment process (AHP ...

Chemicals send Disneyland workers to hospital  Dec 16, 2005
OCRegister, ...the Anaheim Fire Department. The chemicals were hydrochloric acid and sodium hydrochloride, a bleach, she said. She said the result ...

Extended-Release Metformin Combo Drug Given the Green Light  Dec 20, 2005
Diabetes Interview, Glumetza, a once-daily extended-release formulation of metformin hydrochloride, was granted FDA approval in June 2005 for the treatment of type 2 diabetes. ...

Abelson-Taylor Wins International Award Competitions  Dec 19, 2005
PharmaLive.com (press release), ...an acne product used in the treatment of acne vulgaris, and a Sliver Award in the Dimensional Mailer Campaign for Allegra (fexofenadine hydrochloride), used to ...

Cat, cocaine and tik have firm hold on South Africans  Dec 20, 2005
Mail & Guardian Online, ...in five provinces in the first six months of this year, almost one in three reported having used crack cocaine, cocaine hydrochloride, methamphetamine (tik ...

Hyperphosphatemia and Mortality: What's The Connection  Dec 27, 2005
Medscape (subscription) ...of phosphorus from the gut include aluminum hydroxide, calcium carbonate, calcium acetate, magnesium carbonate, sevelamer hydrochloride, and lanthanum carbonate ...

Irritable Bowel Syndrome (IBS)  Dec 16, 2005
WSOCtv.com, ...for IBS. Alosetron hydrochloride (Lotronex®) relaxes the colon and slows the passage of waste products through the bowel. The drug ...

Facing the hard facts...  Dec 21, 2005
The Kerryman, It is generally sold on the street as cocaine hydrochloride - a fine, white crystalline powder, soluble in water, known in Kerry as ‘coke’, ‘C’ and ...

Gerber: Protect your pets against insect infections  Dec 16, 2005
Mansfield News, Luckily their vet knew exactly what was causing the problem and after receiving a shot of Benadryl (diphenhydramine hydrochloride), an antihistamine, their dog ...

Two Customs officials retire  Dec 16, 2005
Saipan Tribune, Interior and the Australian Customs Services, has been responsible for the seizure of millions of dollars in illegal drugs such as methamphetamine hydrochloride ...

'Drug peddler' falls  Dec 30, 2005
Sun.Star, Mangaliman said the suspect was collared in the act of selling suspected methamphetamine hydrochloride known as shabu, weighing some .1367 grams, to a poseur ...


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