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Picrotoxin
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DRUG INFO Picrotoxin
Drug Name:
Picrotoxin
Indication: For the treatment of respiratory distress
Pharmacology: Picrotoxin is used as a central nervous system stimulant, antidote, convulsant, and GABA (gamma aminobutyric acid) antagonist. It is a noncompetitive antagonist at GABAA receptors and thus a convulsant. Picrotoxin blocks the research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially barbiturates.
Mechanism Of Action: Binds to the GABAA and GABA-C receptors and blocks the action of the receptors.
Drug Category: Anti-barbituates; Stimulants;
Brand Names/Synonyms: COCCULINE; Cocculin; Cocculus; Coques Du Levant; Fish Berry; Indian Berry; Oriental Berry; PICROTOXIN; Picrotoxin; Picrotoxin of Fishberries; Picrotoxinin
Dosage Forms: Not Available
Absorption: Not Available
Interactions: Not Available
Chemical IUPAC Name: Not Available
Chemical Formula: C30H34O13
Half Life: Not Available
Drug Type: Non-Approved Drug
# Accession No: APRD00269
CAS Registry Number: 124-87-8
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Picrotoxin News (When available)
The Logic of Chemical Synthesis Dec 24, 2005 MediaGab Molecules shown include Longifolene, Porantherine, Gibberellic acid, Picrotoxinin, and Ginkgolide B. The strategies help generate possible synthetic pathways ...
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