Pharmacology: Physostigmine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor which effectively increases the concentration of acetylcholine at the sites of cholinergic transmission. Physostigmine is used to treat glaucoma. Because it crosses the blood-brain barrier, it is also used to treat the central nervous system effects of atropine overdose and other anticholinergic drug overdoses. Physostigmine can reverse both central and peripheral anticholinergia.
Mechanism Of Action: By interfering with the metabolism of acetylcholine, physostigmine indirectly stimulates both nicotinic and muscarinic receptors.
Drug Category: Antiglaucomic Agents; Ophthalmics; Parasympathomimetics; ATC:S01EB05; ATC:V03AB19
Interactions:
DrugBank: Interactions for Physostigmine
Interactions for Physostigmine:
No information provided.
Chemical IUPAC Name: Not Available
Chemical Formula: C15H21N3O2
Half Life: Not Available
Drug Type: Approved Drug
# Accession No: APRD00406
CAS Registry Number: 57-47-6
Physostigmine News (When available)
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