Phenylpropanolamine resources


DRUG INFO
Phenylpropanolamine

Drug Name: Phenylpropanolamine

Indication: For the treatment of nasal congestion, control of urinary incontinence, priapism and obesity



Pharmacology: Phenylpropanolamine (PPA), a sympathomimetic agent structurally similar to pseudoephedrine, is used to treat nasal congestion. Phenylpropanolamine is found in appetite suppressant formulations and with guaifenesinin in cough-cold formulations.

Mechanism Of Action: Phenylpropanolamine acts directly on alpha- and, to a lesser degree, beta-adrenergic receptors in the mucosa of the respiratory tract. Stimulation of alpha-adrenergic receptors produces vasoconstriction, reduces tissue hyperemia, edema, and nasal congestion, and increases nasal airway patency. PPA indirectly stimulates beta-receptors, producing tachycardia and a positive inotropic effect.

Drug Category: Adrenergic alpha-Agonists; Appetite Depressants; Nasal Decongestants; ATC:R01BA01; Sympathomimetics

Brand Names/Synonyms: (+-)-Phenylpropanolamine; Acutrim; Acutrim (TN); Ami-Tex; Codimal; Conex; Contuss; Despec; Dexatrim; Dura-Vent; Entex; Gentab; Guaipax; Myminic; Naldecon; Nolex; Partuss; Phenoxine; Phenyldrine; Phenylfenesin; Propagest; Rhindecon; Rhymed; Snaplets; Triaminic; ULR; Vanex; (±)-Norephedrin

Dosage Forms: Tablet, injection, SYRUP

Absorption: reduced bioavailability (about 38%) from gastrointestinal tract because of first pass metabolism by monoamine oxidase in the stomach and liver

Interactions: [an error occurred while processing this directive]

Chemical IUPAC Name: 2-amino-1-phenyl-propan-1-ol

Chemical Formula: C9H13NO

Half Life: 2.1 to 3.4 hours.

Drug Type: Approved Drug

# Accession No: APRD00457

CAS Registry Number: 14838-15-4



Phenylpropanolamine News
(When available)


Fighting Your Age: Doctors and Fitness Trainers Team up to Make ...  Jan 13, 2006
I-Newswire.com (press release) ...begin with a consultation with anti-aging Specialist Dr. Frank Comstock, MD, who administers a body composition and bone density test using DEXA Scan technology ...

News Briefs  Jan 11, 2006
Irish Medical Times, The HSE eastern region has signed a contract for the supply and installation of a Dual Energy X-Ray Absorptiometry (DEXA) system at the Kildare hospital. ...

Premature to say atazanavir not linked to fat loss, says ...  Dec 12, 2005
Aidsmap, AZT/3TC. The study showed modest increases in body fat on both drugs as measured by DEXA scan at baseline and week 48. Although ...

Combination HIV Drug Trizivir, Along with Tenofovir, Well ...  Dec 22, 2005
DG News ...the investigators assessed changes from baseline in fat distribution and bone density by whole body and regional dual energy X-ray absorptiometry (DEXA) at one ...

5 to stay alive  Jan 3, 2006
Cincinnati.com, DEXA (dual-energy X-ray absorptiometry) scan: This test measures bone density in the hip or lower back as a means to look for osteoporosis, or loss of bone. ...

Naturopath offers remedies to women who want to maintain healthy ...  Jan 3, 2006
Newstarget.com, A DEXA test gives you a T-score, which is a measurement of your bone density compared with that of women who are at peak bone density. ...

New, 12:20 pm: Father of slain boy opposes plea bargain for teen ...  Dec 16, 2005
Grand Junction Sentinel, Mesa Developmental Services is seeking enthus....(more). MA/ Dexa Scan Tech needed for a 21 physician group. Will train the righ....(more). ...

Limb gat gains lower when switching from AZT to abacavir or ...  Dec 15, 2005
Aidsmap, However, limb fat increase, as measured by DEXA scans, was greater in those individuals who had switched from d4T rather than AZT. ...

A closer look at nuclear scanners  Dec 28, 2005
TMCnet ...surgery.". The new scanner is the latest device to be installed there and joins existing devices including MRI, CT and Dexa scanners. ...

Bone Quality Regulator Identified, Suggests Drug Target  Dec 14, 2005
Science Daily (press release) ...test done alone, a new study indicates. BMD measurement with DEXA is presently ... > full story. The study will be reported later ...

Dog communicates with universe  Jan 12, 2006
Norman Transcript, ...deter deer. Over-the-counter phenylpropanolamine (Dexatrim) can help dogs hold their urine better when they are incontinent. (But ...

JUST AMONG FRIENDS  Jan 4, 2006
Philadelphia Neshoba Democrat, Mr. Young had a store of what was then called “Tin Pan Alley,� now East Beacon on the street with the Coffee Bean, Entex, The Carousel, Stribling Drugs, etc ...

City council clears way for sale of local cable service  Jan 3, 2006
Lufkin Daily News, Approved, on second reading, ordering CenterPoint Energy Entex to “cease and desist from charging illegal and unlawful rates and requiring refunds.� The ...

Council approves cease and desist order against CenterPoint  Dec 23, 2005
Jacksonville Daily Progress, The only agenda item for the meeting was to approve a “cease and desist� order to keep Centerpoint Energy Entex from charging “illegal and unlawful rates ...

YACHTING: Realists refuse to surrender to westerlies  Jan 2, 2006
Hawke's Bay Today, Some of the sailors racing in the Nolex 25 class were preparing for the national championship to be held at the Napier club, in conjunction with the Hartley ...

Eminem: A cultural rebel to the core  16 Jan 2006
Hindustan Times, ...style. He called it the "inside rhyme". At that time in the still early days of rap, if even two lines rhymed it would be enough. But ...

HOSPITALITY DEPT.  16 Jan 2006
New Yorker, ...“Oh, look, La Fenice,� she said, pronouncing the word so that it rhymed with “Venice.� She was quickly corrected: “No, it’s La Fe-nee-chay ...

Play It Again, Em  Jan 15, 2006
E! Online Within a year, he recorded the scathing track "Kim," in which he rhymed about killing his missus, giving the public insight into what had become an extremely ...

Martin asks NDP backers to vote Liberal  Jan 15, 2006
Ottawa Citizen, Mr. Martin rhymed off a list of areas where he claims Mr. Harper will turn back the clock: Cancelling a federal-provincial child-care agreement; reneging on ...

VALIE EXPORT : 3 Experimental Short Films  Jan 13, 2006
DVDTimes.co.uk, In this case she also appears in front of a large photographic reproduction bearing two children, both of whom are rhymed with her. ...

A Joyous Sound  Jan 15, 2006
Syracuse Post Standard, Ceili Rain started with the happy song "Jigorous," one in which all seven of the musicians heeded Halligan's rhymed orders to be vigorous. ...

Poet chose a heroic task  Jan 15, 2006
Sun-Sentinel.com, A crown of sonnets consists of seven sonnets written on a theme, with the last line of each rhymed, 14-line poem serving as the first line of the next. ...

Got change? Support your local poet  Jan 13, 2006
Daily Trojan Online, ...for! If their poems rhymed, just think how much more useful they would be. How many words rhyme with "orange"? Very few, I suppose. ...

No Disassemble  Jan 13, 2006
Mammoth Press ...album. First of all “fuck� is rhymed with “luck� which is just downright awesome. Then it’sa battle of synths verses drums. ...

Bethmale -- a cheese to please from the Midi-Pyrenees  Jan 12, 2006
San Francisco Chronicle, Bethmale. From the name, I presumed it was British, and my inner pronunciation guide rhymed it with Wensleydale. Wrong. Bethmale ...

HOW THE MUSIC SOLD ITS SOUL  Jan 12, 2006
Irish Times, ...braggadocio really taken over? It may be time to ask again the question Public Enemy once rhymed: who stole the soul? A good place ...

Like 'The Simpsons'? You'll love Stravinsky  Jan 10, 2006
philly.com, It is as relevant as ever. Leonard Nimoy and Richard Thomas star in a new rhymed version by Isaiah Sheffer in March at New York's Symphony Space. ...

Selfless McNeill leading way for So. Connecticut  Jan 12, 2006
Pocono Record, He's 'there every night.' Practice or games, he's there. He tried as hard as he might," rhymed former sports editor Bill Barnhart. ...

Cowboy Poets to Gather in Colorado  Jan 10, 2006
New West, In "The Cowboy Poetry Gathering: Rounding Up the Dollars to Grow a Home on The Range," he writes, "Cowboy poetry is rhymed, metered verse written by someone ...

Lit Crit 101  Jan 12, 2006
TheStranger.com, ..."While your typical Poetry 101 workshop will churn out blank verse like crazy, I was writing really tightly metered, rhymed couplets," he says. ...

Region 8 launches literary contest on centennial of Filipino ...  Jan 8, 2006
Philippine Information Agency, ...category. For the poetry writing competition, entries must be a collection of five to ten poems and may be rhymed or in free verse. ...

Celebrating Valentine's Day: It's Never Been Easier to Send ...  Jan 6, 2006
Emediawire (press release), ...his confinement in the Tower of London after the Battle of Agincourt, a young Frenchman, Charles, Duke of Orleans, sent several poems or rhymed love letters to ...

SUB TITLES : 4 episodes of fanciful fun on Gerald McBoing Boing  Jan 5, 2006
Arkansas Democrat-Gazette (subscription), Marvin Miller provided the voice and the narration for this charming, richly rhymed, 8-minute miniature, on which Seuss collaborated with Bill Scott (of Rocky ...

Eric Tough  Jan 2, 2006
The Herald, Tough – his surname rhymed with the Scots word "sough" – was born and schooled in Banchory, Kincardineshire, and was a graduate of both Aberdeen University ...

Laughing All the Way to the Polls  Jan 3, 2006
AlterNet, Less palatable was her earlier, widely circulated jab at Ferraro, whom she called something she "couldn't say" that "rhymed with rich." In her subsequent ...

Great minds thinking alike  Jan 6, 2006
Times Online, ...and-black-bread snacks and drinking an elegant quantity of wine and listening to (a) a clever essay by Pope and (b) an equally clever rhymed denunciation of ...

'Hug your kids'  Dec 27, 2005
St. Petersburg Times, Next to her were daughters Tiara and Jade, and sons Eric and Jordan. Doris Harris, James' maternal grandmother, read from prepared remarks that rhymed. ...

Making case for Diogu  Dec 27, 2005
San Francisco Chronicle, Before he rhymed, the head coach devoted several minutes of his pregame news conference Monday night to containing the Ike Diogu movement. ...

50 Cent hosts Policeman's Ball  Dec 20, 2005
Toronto Star, ...by a trailer for 50 Cent's Get Rich or Die Tryin' and a brief mini-doc on his rise to glory, the program was a hasty, perfunctorily rhymed whistle-stop tour ...

Luzon folk keep alive Misa de Gallo traditions  Dec 18, 2005
INQ7.net, As other villagers wait for their turn to attend Mass, they continue to sing the long Salamon, a 2,500-line Ibanag Christmas carol in rhymed quatrains. ...

Directed by Woody Allen  Dec 28, 2005
New York Press, ...brutal little plan, and the world’s absolute inability to deal with it.) Late in the film, the image of the frozen tennis ball is visually rhymed in another ...

Team insists Savage’s job is intact despite other reports  Dec 31, 2005
Canton Repository (subscription), He is one of those fellows who needs to run so his mental rhythm can rhyme with his body. Friday at 76 Lou Groza Blvd., nothing rhymed for a while. ...

It’s Not Polite to Use the “Câ€? Word in Public  Dec 18, 2005
American Daily, ...the “C-word� in public. “The 12 Days of Christmas� is more than just a whimsical, well-rhymed song. It was actually written ...

Who brings up the rear on Santa's sleigh?  Dec 24, 2005
Cleveland Plain Dealer, ...and Blixen. (The theory on snopes.com is that Donder rolled off the tongue easier in English, and Blixen rhymed with Vixen. Moore ...

Hawaii migration literary tilt launched  Dec 29, 2005
Philippine Information Agency, 2006. For the poetry writing competition, entries must be a collection of 5 to 10 poems and may be rhymed or in free verse. Essay ...

The impact of rhymes and words  Dec 21, 2005
Deccan Herald, ...are done: nChildren who are struggling with recognising and creating rhymed words may need more direct intervention. Initial rhyme ...

Recommended holiday reads: Alan Perrott  Dec 21, 2005
New Zealand Herald, Personally, I think he’s still resolving the anguish he has oft described of the day when his schoolmates discovered his name rhymed with ladies’ bits. ...

It's a date  Dec 19, 2005
Times Herald-Record, ...an egg that is blue-/-A three-leaf clover, a cat from a zoo ..." Finding those items and more in the 12 wonderfully inventive photographs with rhymed text is a ...

Embracing the Seasons of Heaven  Dec 21, 2005
New York Sun, ...respectively. They also are rhymed, and pronunciation changes over centuries have made the rhyme unclear even to most Chinese today. ...

Every song has a story  Dec 28, 2005
Wilkes Barre Times-Leader, When you listen to the lyrics in the verse, it is a well rhymed story about school aged sexual adventures É Then the chorus comes in: "walk this way, walk ...

Overlooked in '05  Dec 21, 2005
Riverfront Times, ...is the very definition of "rueful," and it's hard to argue with a lyric like "I'd be havin' nightmares if I could only sleep." Plus "theses" rhymed with "feces ...

Cold Advice  16 Jan 2006
Washington Post, These ingredients include guaifenesin (found in Robitussin and other cough remedies) and dextromethorphan (found in Robitussin, Vicks, Triaminic, Sucrets and ...

Deveaux Calls for NS to Follow Manitoba's Example on Crystal Meth ...  16 Jan 2006
Halifax Live, ...that such a highly dangerous drug could be manufactured from such common products as Benylin for Infants, Sudafed Decongestant and Triaminic Pediatric Oral ...

RSV: It's common, contagious, disgusting  Jan 8, 2006
Evansville Courier & Press (subscription), Use Tylenol for fever control and prop your child upright for easier breathing. A decongestant/expectorant such as Triaminic Yellow may loosen secretions. ...

Go carefully with medications for babies  Jan 14, 2006
VillageSoup Belfast, Popular brand names of these include Sudafed, Benadryl, Robitussin and a host of combinations such as Triaminic, Dimetapp, Tylenol Cold and Cough. ...

Drug shipped from Indy killed 5  Jan 11, 2006
Indianapolis Star, DXM: Robitussin, Vicks 44, Tiaminic, Pertussin DM, Benylin, Alka-Seltzer Plus, Coricidin, Contac, Comtrex, Thera-Flu, Sudafed, Triaminic, Dimetap, Tylenol Cold ...

Do Cough Syrups Work?  Jan 10, 2006
WILX-TV, According to the study, the cough suppressing and 'expectorant' ingredients in products like Robitussin, Dimetapp and Triaminic aren't particularly effective ...

Universal Life Resources Settles Commission Charges with NY  Jan 5, 2006
Insurance Journal ..."The agreement with ULR represents another milestone toward curtailing undisclosed contingent commissions in the insurance industry," Spitzer said. ...

Universal Life settles with New York for $2 mln  Jan 5, 2006
Reuters Under the agreement, Douglas Cox, the chief executive of San Diego-based ULR, and his affiliated companies will provide $2 million in restitution to ...

Group against acquisition of Loboc water rights, fears tourism ...  Jan 7, 2006
Bohol Chronicle, LHP). The United Lobocanons for Reconstruction (ULR) said they were shocked of Sta. ... government.�. ULR pointed out that the acquisition by Sta. ...

Broker Universal Life of SD agrees to settle NY lawsuit  Jan 7, 2006
San Diego Union Tribune, But Cox did agree to pay restitution to policy holders across the country, according to Spitzer's office. "The agreement with ULR represents another milestone ...

Business briefs, January 6  Jan 5, 2006
Rocky Mountain News, The money, paid by ULR and former Chief Executive Officer Douglas Cox, will reimburse policyholders around the country who may have been harmed. ...

Spitzer strikes again  Jan 6, 2006
Post Magazine (subscription), Under the agreement, Douglas Cox, president and chief executive of Universal Life Resources (ULR), based in San Diego, and his affiliated companies will ...


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