Phensuximide resources


DRUG INFO
Phensuximide

Drug Name: Phensuximide

Indication: For the treatment of epilepsy



Pharmacology: Phensuximide suppresses the paroxysmal three cycle per second spike and wave EEG pattern associated with lapses of consciousness in absence (petit mal) seizures. The frequency of attacks is reduced by depression of nerve transmission in the motor cortex.

Mechanism Of Action: Phensuximide's mechanism of action not understood, but may act in inhibitory neuronal systems that are important in the generation of the three per second rhythm

Drug Category: Anticonvulsants; Antiepileptic Agents; ATC:N03AD02

Brand Names/Synonyms: Epimid; Fenosuccimide; Fensuccimide [DCIT]; Fensuximida [INN-Spanish]; Lifene; Methylphenylsuccinimide; Milontin; Milonton; Mirontin; Mirotin; PM 334; Phenosuccimide; Phensuximid; Phensuximide; Phensuximide [BAN:INN]; Phensuximidum [INN-Latin]; Phenylsuximide; Succitimal; (+/-)-N-Methyl-2-phenylsuccinimide; 1-Methyl-3-Phenylsuccinimide; EINECS 201-664-6; Milontin (TN); N-Methyl-alpha-phenolsuccinimide; N-Methyl-alpha-phenylsuccinimide; N-Methyl-2-phenylsuccinimide; N-Methyl-alpha-phenolsuccinimide; N-Methyl-alpha-phenylsuccinimide; Phensuximide (USP); Succinimide, N-methyl-2-phenyl-

Dosage Forms: CAPSULES

Absorption: Rapid and complete

Interactions: Not Available



Chemical IUPAC Name: 1-methyl-3-phenyl-pyrrolidine-2,5-dione

Chemical Formula: C11H11NO2

Half Life: Not Available

Drug Type: Approved Drug

# Accession No: APRD00496

CAS Registry Number: 86-34-0



Phensuximide News
(When available)


Mylan Laboratories and Forest Laboratories Announce Nebivolol ...  Jan 12, 2006
PharmaLive.com (press release), ...and maintenance treatment of major depressive disorder and for generalized anxiety disorder in adults; Namenda(R) (memantine HCl), an N- methyl-D-aspartate ...

Ebixa (memantine) Demonstrates Longer Term Benefits for Moderate ...  Jan 9, 2006
DG News Ebixa (memantine) is a moderate affinity NMDA (N-methyl-D-aspartate) receptor antagonist that is unique among Alzheimer's disease treatments since it targets ...

Memantine (Namenda) Found Effective for Advanced Alzheimer's ...  Jan 10, 2006
SeniorJournal.com, According to the FDA, the drug is an N-methyl-D-asparate (NMDA) antagonist and is thought to work by blocking the action of the chemical glutamate. ...


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