Papaverine resources


DRUG INFO
Papaverine

Drug Name: Papaverine

Indication: Impotence



Pharmacology: Papaverine is a nonxanthine phosphodiesterase inhibitor for the relief of cerebral and peripheral ischemia associated with arterial spasm and myocardial ischemia complicated by arrhythmias. The main actions of Papaverine are exerted on cardiac and smooth muscle. Like qathidine, Papaverine acts directly on the heart muscle to depress conduction and prolong the refractory period. Papaverine relaxes various smooth muscles. This relaxation may be prominent if spasm exists. The muscle cell is not paralyzed by Papaverine and still responds to drugs and other stimuli causing contraction. The antispasmodic effect is a direct one, and unrelated to muscle innervation. Papaverine is practically devoid of effects on the central nervous system. Papaverine relaxes the smooth musculature of the larger blood vessels, especially coronary, systemic peripheral, and pulmonary arteries.

Mechanism Of Action: Perhaps by its direct vasodilating action on cerebral blood vessels, Papaverine increases cerebral blood flow and decreases cerebral vascular resistance in normal subjects; oxygen consumption is unaltered. These effects may explain the benefit reported from the drug in cerebral vascular encephalopathy.

Drug Category: Vasodilator Agents; Vasodilator Agents; ATC:A03AD01; ATC:G04BE02

Brand Names/Synonyms: Alapav; Artegodan; Cardiospan; Cardoverina; Cepaverin; Cerebid; Cerespan; Chlorhydrate de Papaverine; Delapav; Dilaves; Dispamil; Drapavel; Durapav; Dynovas; Forpavin; Genabid; HSDB 3147; Myobid; Optenyl; PAPAVERINE; Pameion; Pamelon; Panergon; Pap H; Papacon; Papalease; Papanerin; Papanerin-Hcl; Papanerine; Papavarine Chlorhydrate; Papaverin; Papaverine Chlorohydrate; Papaverine Hcl; Papaverine Hydrochloride; Papaverine Monohydrochloride; Papaverine, Hydrochloride; Papaverinium Chloride; Papaversan; Papital T.R.; Paptial T.R.; Pavabid; Pavabid Hp; Pavacap; Pavacels; Pavacen; Pavacot; Pavadel; Pavagen; Pavakey; Pavarine; Pavased; Pavatest; Pavatine; Pavatym; Paverolan; Paveron; Pavnell; Qua Bid; Ro-Papav; Robaxapap; Spasmo-Nit; Therapav; Vasal; Vaso-Pav; Vasospan

Dosage Forms: LIQUID

Absorption: Not Available

Interactions: DrugBank: Interactions for Papaverine

Interactions for Papaverine:


No information provided.

 





Chemical IUPAC Name: 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoquinoline

Chemical Formula: C20H21NO4

Half Life: 0.5-2 hours

Drug Type: Approved Drug

# Accession No: APRD00628

CAS Registry Number: 61-25-6



Papaverine News
(When available)


‘Paramapadha vasal’ opened in Andal temple  Jan 11, 2006
Newindpress, Thousands of devotees thronged the Sri Andal temple here on Tuesday to participate in the Vaikunda Ekadasi festival and to pass through the ‘Paramapadha vasal ...

Devotees throng temple on the occasion of Vaikunta Ekadasi  Jan 9, 2006
Webindia123, The festive deity ''Lord Namperumal'' clad in glittering gem-studded armour (Ratha Angi) entered the ''Paramapada Vasal'' also called as ''Sorga Vasal ...

Devotees throng temple on Vaikunta Ekadasi  Jan 9, 2006
Hindu, The festive deity "Lord Namperumal" clad in the glittering gem-studded armour (Ratha Angi) entered the "Paramapada Vasal" also called as "Sorga Vaasal ...

Vaikunta Ekadesi celebrated with films  Jan 10, 2006
News Today, Vaikunta Ekadesi is marked by spiritual activities and on this day, the Lord with his consorts pass through the Paramapatha Vasal in all Vaishnavite temples ...

Government concessions for traffic ward sought  Jan 5, 2006
Newindpress, At present these traffic ward regulate traffic at Goripalayam, Periyar bus stand, Keezha Vasal, Meenakshi Amman Temple on Tuesdays and Fridays from 6.30 pm to ...

Around the City  Jan 8, 2006
Hindu, The vaikunta vasal will be thrown open on Tuesday morning. The temple is being renovated at a cost of Rs. 14 lakh with two-tier vimanam and a mahamandapam. ...

Vaikunda ekadasi festival begins on Jan 9  Jan 6, 2006
Newindpress, The programme is as follows: 9-1-2006 6 pm Mohini avadhara alangaram; 8 PM religious discourses. 10-1-2006 5 am Vaikunda vasal thirappu. ...

Developer eyes Galway residential/retail complex  Jan 4, 2006
The Saratogian, ...wetlands. 'The neighbors are not happy about this,' said Dorothy Panasuk, who owns Vasal's grocery store near the intersection. ...

'Vaikunta Ekadasi' in TN temple from Dec 30  Dec 26, 2005
NewKerala.com, ...adorned with rubies and precious stones) will be taken out of the sanctum sanctorum in a procession in the wee hours through the 'Paramapada Vasal' (Gateway to ...


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