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Papaverine
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DRUG INFO Papaverine
Drug Name:
Papaverine
Indication: Impotence
Pharmacology: Papaverine is a nonxanthine phosphodiesterase inhibitor for the relief of cerebral and peripheral ischemia associated with arterial spasm and myocardial ischemia complicated by arrhythmias. The main actions of Papaverine are exerted on cardiac and smooth muscle. Like qathidine, Papaverine acts directly on the heart muscle to depress conduction and prolong the refractory period. Papaverine relaxes various smooth muscles. This relaxation may be prominent if spasm exists. The muscle cell is not paralyzed by Papaverine and still responds to drugs and other stimuli causing contraction. The antispasmodic effect is a direct one, and unrelated to muscle innervation. Papaverine is practically devoid of effects on the central nervous system. Papaverine relaxes the smooth musculature of the larger blood vessels, especially coronary, systemic peripheral, and pulmonary arteries.
Mechanism Of Action: Perhaps by its direct vasodilating action on cerebral blood vessels, Papaverine increases cerebral blood flow and decreases cerebral vascular resistance in normal subjects; oxygen consumption is unaltered. These effects may explain the benefit reported from the drug in cerebral vascular encephalopathy.
Drug Category: Vasodilator Agents; Vasodilator Agents; ATC:A03AD01; ATC:G04BE02
Brand Names/Synonyms: Alapav; Artegodan; Cardiospan; Cardoverina; Cepaverin; Cerebid; Cerespan; Chlorhydrate de Papaverine; Delapav; Dilaves; Dispamil; Drapavel; Durapav; Dynovas; Forpavin; Genabid; HSDB 3147; Myobid; Optenyl; PAPAVERINE; Pameion; Pamelon; Panergon; Pap H; Papacon; Papalease; Papanerin; Papanerin-Hcl; Papanerine; Papavarine Chlorhydrate; Papaverin; Papaverine Chlorohydrate; Papaverine Hcl; Papaverine Hydrochloride; Papaverine Monohydrochloride; Papaverine, Hydrochloride; Papaverinium Chloride; Papaversan; Papital T.R.; Paptial T.R.; Pavabid; Pavabid Hp; Pavacap; Pavacels; Pavacen; Pavacot; Pavadel; Pavagen; Pavakey; Pavarine; Pavased; Pavatest; Pavatine; Pavatym; Paverolan; Paveron; Pavnell; Qua Bid; Ro-Papav; Robaxapap; Spasmo-Nit; Therapav; Vasal; Vaso-Pav; Vasospan
Dosage Forms: LIQUID
Absorption: Not Available
Interactions:
DrugBank: Interactions for Papaverine
Interactions for Papaverine:
No information provided.
Chemical IUPAC Name: 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoquinoline
Chemical Formula: C20H21NO4
Half Life: 0.5-2 hours
Drug Type: Approved Drug
# Accession No: APRD00628
CAS Registry Number: 61-25-6
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Papaverine News (When available)
‘Paramapadha vasal’ opened in Andal temple Jan 11, 2006 Newindpress, Thousands of devotees thronged the Sri Andal temple here on Tuesday to participate in the Vaikunda Ekadasi festival and to pass through the ‘Paramapadha vasal ...
Devotees throng temple on the occasion of Vaikunta Ekadasi Jan 9, 2006 Webindia123, The festive deity ''Lord Namperumal'' clad in glittering gem-studded armour (Ratha Angi) entered the ''Paramapada Vasal'' also called as ''Sorga Vasal ...
Devotees throng temple on Vaikunta Ekadasi Jan 9, 2006 Hindu, The festive deity "Lord Namperumal" clad in the glittering gem-studded armour (Ratha Angi) entered the "Paramapada Vasal" also called as "Sorga Vaasal ...
Vaikunta Ekadesi celebrated with films Jan 10, 2006 News Today, Vaikunta Ekadesi is marked by spiritual activities and on this day, the Lord with his consorts pass through the Paramapatha Vasal in all Vaishnavite temples ...
Government concessions for traffic ward sought Jan 5, 2006 Newindpress, At present these traffic ward regulate traffic at Goripalayam, Periyar bus stand, Keezha Vasal, Meenakshi Amman Temple on Tuesdays and Fridays from 6.30 pm to ...
Around the City Jan 8, 2006 Hindu, The vaikunta vasal will be thrown open on Tuesday morning. The temple is being renovated at a cost of Rs. 14 lakh with two-tier vimanam and a mahamandapam. ...
Vaikunda ekadasi festival begins on Jan 9 Jan 6, 2006 Newindpress, The programme is as follows: 9-1-2006 6 pm Mohini avadhara alangaram; 8 PM religious discourses. 10-1-2006 5 am Vaikunda vasal thirappu. ...
Developer eyes Galway residential/retail complex Jan 4, 2006 The Saratogian, ...wetlands. 'The neighbors are not happy about this,' said Dorothy Panasuk, who owns Vasal's grocery store near the intersection. ...
'Vaikunta Ekadasi' in TN temple from Dec 30 Dec 26, 2005 NewKerala.com, ...adorned with rubies and precious stones) will be taken out of the sanctum sanctorum in a procession in the wee hours through the 'Paramapada Vasal' (Gateway to ...
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