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Oxytocin
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DRUG INFO
Oxytocin
Drug Name:
Oxytocin
Indication: To assist in labor, elective labor induction, uterine contraction induction
Pharmacology: Used to induce labor or to enhance uterine contractions during labor. Uterine motility depends on the formation of the contractile protein actomyosin under the influence of the Ca2+-dependent phosphorylating enzyme myosin light-chain kinase. Oxytocin promotes contractions by increasing the intracellular Ca2+, which in turn activates myosins light chain kinase.. Oxytocin has specific receptors in the muscle llining of the uterus and the receptor concentration increases greatly during pregnancy, reaching a maximum in early labor at term.
Mechanism Of Action: Binds the oxytocin receptor which leads to an increase in intracellular calcium levels.
Drug Category: Anti-tocolytic Agents; Labor Induction Agents
Brand Names/Synonyms: Oxytocin; Pitocin; Syntocinon; Oxytocin (BAM Biotech); Pitocin (Parke-Davis); Syntocinon (Sandoz)
Dosage Forms: Not Available
Absorption: Not Available
Interactions: Not Available
Chemical IUPAC Name: Oxytocin
Chemical Formula: C43H67N11O13S2
Half Life: 1-6 min
Drug Type: Approved Drug
# Accession No: BIOD00016
CAS Registry Number: 50-56-6
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Oxytocin News
(When available)
Ask Rachelle, the childbirth expert Jan 10, 2006
Jerusalem Post, When the pain is taken away, oxytocin frequently needs to be given intravenously using the synthetic drug, Pitocin. Because contractions ...
Hospital's first baby of 2006 is a boy Jan 7, 2006
New Milford Times, I came to the hospital and they gave me Pitocin. His heart rate dropped once. They got it back up and they decided to up the Pitocin because I wasn't dilating. ...
Does an epidural put me or my baby at risk? Dec 27, 2005
MSNBC In addition, among women using epidurals, there was a slight increase (about 18 percent) in the need for pitocin, a synthetic hormone that is used to induce or ...
Baby waits for New Year's Jan 2, 2006
San Luis Obispo Tribune, But the soon-to-be-third-time mom sat all day Friday with no contractions. The doctors gave her Pitocin, a drug used to induce labor. Still nothing. ...
Study says birth coaches unnecessary Dec 30, 2005
Blogging Baby, ...daughter. I'd been in pitocin-induced labor for 14 hours and at that point had been pushing for an hour. Simply put, I was exhausted. ...
Doctor accused over birth that ended in tragedy Jan 4, 2006
ic Liverpool, It is alleged she instructed a midwife to increase the dosage of a drug called Syntocinon, used to induce labour, from 18mls per hour, eventually up to 96mls ...
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