|
Oxyphencyclimine
resources
|
|
|
|
|
|
DRUG INFO
Oxyphencyclimine
Drug Name:
Oxyphencyclimine
Indication: For the treatment of peptic ulcer disease; Relief of smooth muscle spasms in gastrointestinal disorders
Pharmacology: Oxyphencyclimine is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. Oxyphencyclimine is an antimuscarinic, anticholinergic drug.
Mechanism Of Action: Oxyphencyclimine binds the muscarinic acetylcholine receptor. It may block all three types of muscarinic receptors including M-1 receptors in the CNS and ganglia, M-2 receptors in the heart (vagus) and M-3 receptors at the parasympathetic NEJ system. The muscarinic acetylcholine receptors mediate various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Oxphencyclimine inhibits vagally mediated reflexes by antagonizing the action of acetylcholine. This in turn reduces the secretion of gastric acids in the stomach.
Drug Category: Anticholinergic Agents; Antispasmodics; ATC:A03AA01
Brand Names/Synonyms: Antulcus; CHEMBANK1461; Caridan; Cycmin; Daricol; Daricon; Dominil; Enterex; Gastrix; Manir; Naridan; O7755; Oxifencicliminum [Inn-Spanish]; Oximin; Oxiphencycliminum; Oxyphencyclimine; Oxyphencyclimine Hydrochloride; Oxyphencycliminum [Inn-Latin]; Setrol; Spazamin; Syklifen; Ulcociclinina; Vio-Thene; W-T Anticholinergic; Zamanil
Dosage Forms: Not Available
Absorption: Not Available
Interactions: Not Available
Chemical IUPAC Name: (1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenyl-acetate
Chemical Formula: C20H28N2O3
Half Life: Not Available
Drug Type: Approved Drug
# Accession No: APRD00399
CAS Registry Number: 125-53-1
|
|
|
|
|
|
Oxyphencyclimine News
(When available)
Mini Fuel Station Operators Laud Cancellation Of RM15,000 Deposit Jan 11, 2006
Bernama, An operator in TERENGGANU, Wan Kuntum Ngah, 65, when met at her shop at Kampung Batu Hampar, Manir in Kuala Terengganu, said she was running a small business. ...
AL bags five, BNP two, independent one Dec 29, 2005
Financial Express.bd, ...e-Islami got 5243 votes. Besides, AL backed candidate Saad Manir Ahmed Jentu got 4604 votes. Awami League supported candidate Aminul ...
Hours of rain cause havoc Dec 22, 2005
New Straits Times, In the state capital, flash floods hit Manir, Pulau Musang and Kuala Nerus, while in Setiu, Kampung Pancur Merah, Guntung and Jabi have been affected. ...
|
|
|
