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Olopatadine
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DRUG INFO
Olopatadine
Drug Name:
Olopatadine
Indication: For the treatment of the signs and symptoms of allergic conjunctivitis.
Pharmacology: Used to treat allergic conjunctivitis (itching eyes), olopatadine inhibits the release of histamine from mast cells. It is a relatively selective histamine H1 antagonist that inhibits the in vivo and in vitro type 1 immediate hypersensitivity reaction including inhibition of histamine induced effects on human conjunctival epithelial cells.
Mechanism Of Action: Olopatadine is a selective histamine H1 antagonist and binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine. Olopatadine is devoid of effects on alpha-adrenergic, dopamine and muscarinic type 1 and 2 receptors.
Drug Category: Anti-allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antihistamines; Histamine H1 Antagonists; ATC:S01GX09
Brand Names/Synonyms: Olopatadine; Olopatadine Hydrochloride; Patanol
Dosage Forms: LIQUID
Absorption: Ophthalmic use of olopatadine usually does not produce measurable plasma concentrations.
Interactions:
DrugBank: Interactions for Olopatadine
Interactions for Olopatadine:
No information provided.
Chemical IUPAC Name: Not Available
Chemical Formula: C21H23NO3
Half Life: 3 hours
Drug Type: Approved Drug
# Accession No: APRD00310
CAS Registry Number: 113806-05-6
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Olopatadine News
(When available)
Red, Itchy, Watery Eyes Jan 14, 2006
About - News & Issues, At first only cromolyn sodium was available, but now other options include the prescription drops Acular, Livostin™, and Patanol®, or the over-the-counter ...
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