Indication: For use as an oral contraceptive in the prevention of pregnancy.
Pharmacology: Norethindrone is a synthetic oral progestin. It is used for contraception or to treat such conditions as secondary amenorrhea, abnormal uterine bleeding, and endometriosis. As an oral contraceptive, norethindrone is available as either a single agent or in combination with an estrogen.
Mechanism Of Action: Progestins diffuse freely into target cells and bind to the progesterone receptor. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once bound to the receptor, progestins slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH surge.
Drug Category: Contraceptives, Oral, Synthetic; Progestins; ATC:G03CA
Absorption: Absolute oral bioavailability approximately 64%
Interactions:
DrugBank: Interactions for Norethindrone
Interactions for Norethindrone:
The effectiveness of progestin-only pills is reduced by hepatic enzyme-inducing drugs such as the anticonvulsants
phenytoin, carbamazepine, and barbiturates, and the antituberculosis drug rifampin. No significant interaction has
been found with broad-spectrum antibiotics.
Chemical IUPAC Name: 17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
Chemical Formula: C20H26O2
Half Life: 7 hours
Drug Type: Approved Drug
# Accession No: APRD00679
CAS Registry Number: 68-22-4
Norethindrone News (When available)
Willie J. WashingtonJan 13, 2006 Greenwood Commonwealth, He is survived by his wife, Genora Jones Washington of Moorhead; 11 daughters, Willie Mae Meeks and Genora Springfield, both of East St. ...
Around the CountiesJan 5, 2006 Louisville Courier-Journal, 16. For ticket information, call Genora Birdsong at 218-3472 or Saundra Couts at 493-1917. A town hall meeting with host state Sen. ...
The Purcell RegisterDec 22, 2005 Purcell Register, He was preceded in death by his parents; one sister, Velda; three brothers, Haskell, Harold and Hubert Newville; one sister-in-law, Genora Newville; a brother ...
Emancipation event to honor 14 womenDec 24, 2005 Athens Banner-Herald (subscription), Lucille Law of Commerce; Mary Lay of Statham; Lucille Cooper of Jefferson; attorney Janice Mathis and Sebelle Jordan of Bogart; 94-year-old Genora Hamm Biggs ...
Citizen of the Year: Dave Jenest, Conservative ActivistDec 28, 2005 Town Hall, Dave Jenest is one of the unsung heroes of the conservative movement. He is known in his community as the local “watchdog� for more reasons than one. ...
2005 Citizens of the Year: The Iraqi PeopleDec 29, 2005 Town Hall, We've run extensive features on our three finalists (The Minutemen Project, Congressmen Mike Pence, and Dave Jenest) this week and received a great deal of ...
Micronor launches controller for automation applicationsJan 3, 2006 Hoist, US electronics firm Micronor claims a new option on its motorized potentiometer offers a simple and inexpensive solution for automating existing systems ...
Current Loop Controller works with motorized potentiometers.Dec 21, 2005 Industrial News Room, Newbury Park, California, November 16, 2005 - Micronor's new MR267 Current Loop Controller (CLC) option remotely controls a motorized potentiometer and/or ...
CAAN to release Necon's aircraftDec 21, 2005 Kathmandu Post, KATHMANDU, Dec 21 - Civil Aviation Authority of Nepal (CAAN) has agreed to release two aircraft leased by Necon Air, kept unused at Tribhuwan International ...
CAAN annuls registeration of Necon aircraftDec 21, 2005 Kantipur Online, KATHMANDU, Dec 22 - Civil Aviation Authority of Nepal (CAAN) has annulled the registration of two airplanes belonging to Necon Air, kept unused at Tribhuwan ...
Government Cancels Registration of Necon's AircraftDec 22, 2005 NewsLine Nepal, The Civil Aviation Authority of Nepal (CAAN) has cancelled the registration of two airplanes belonging to Necon Air that were abandoned at Tribhuwan ...
CAAN annuls registration of Necon AirDec 21, 2005 Nepalnews.com, The Civil Aviation Authority of Nepal (CAAN) has annulled the registration of two airplanes of Necon Air kept unused at Tribhuvan International Airport for the ...
Neocon Muslims: nuisance or threatDec 27, 2005 Milli Gazette, ...campaigns are ignored. America’s necon masters are also busy stigmatizing the distinct identity of the Muslims. Pejorative comments ...
Brig. Gen. Mohammed Buba MarwaDec 26, 2005 Daily Sun, Investigations further showed that the late Head of State thereafter directed the then National Electoral Commission of Nigeria (NECON) to order for the same ...
Infrastructure boom waiting in the wingsJan 8, 2006 Moneyweb, Wilson Bayly Holmes Ovcon chairman Mike Wylie, said in the company's latest annual report, "All indications are that buoyant conditions in the industry should ...
Dietary soy isoflavones inhibit estrogen effects in the ...16 Jan 2006 News-Medical.net, ...not apply to premenopausal women, who have higher and more dynamic hormone levels, or to women taking combined hormone therapy with an estrogen and a progestin ...
US study to test hormone benefits in younger womenJan 5, 2006 Hindustan Times, In July 2002, women taking estrogen and progestin were told to visit their doctors and perhaps stop because of the risk of heart attack, stroke and some forms ...
FDA Approves Osteoporosis Indication for Once-a-Week Hormone ...Jan 4, 2006 PR Newswire (press release), Estrogen/progestin combinations should not be used by women with known or suspected pregnancy, breast cancer, estrogen-dependent neoplasia, undiagnosed ...
Studies: Pill safe for women with lupusDec 20, 2005 Newsday, In Petri's study at 14 US sites, 91 women took estrogen-progestin combination pills, while 92 women in a comparison group got a placebo; all used barrier ...
In this articleDec 30, 2005 Health24.com, Are receiving oestrogen administration, without progestin. ... Low doses can be used in older women who do not have progestin-related complications. ...
Women with lupus can take 'The Pill'?Dec 18, 2005 myDNA.com, Petri's study compared women taking estrogen-progestin combination pills to women taking a placebo - all of them used barrier contraceptives as well. ...
Earlier hormone therapy trial scared women - but it was wrong!Dec 19, 2005 News-Medical.net, Then in 2002, women taking estrogen and progestin were advised to stop taking the drug after the Women's Health Initiative (WHI) said a trial of Wyeth's ...
Intake of synthetic hormones affects sex drive in womenJan 5, 2006 Hindustan Times, MPA is the synthetic progestin used in Prempro, the most widely prescribed hormone replacement therapy in the United States, and in the injectable form of the ...
Bio-identical hormone replacement a new approachJan 3, 2006 Wilkes Barre Times-Leader, Hormone replacement therapy _ providing women with estrogen or estrogen and progestin to ease hot flashes and other uncomfortable symptoms of menopause _ has ...
From a single cell to a complete organJan 5, 2006 Ars Technica ...therapy (HRT) was halted prematurely following the shocking findings that patients taking a combination of oestrogen and progestin had significantly higher ...
News Feature: Hormone in the hot seatDec 29, 2005 Nature.com (subscription), In 1998, after the WHI was already under way, scientists announced the results of the Heart and Estrogen/Progestin Replacement Study 3 , which specifically ...
Compassion in the ERDec 25, 2005 Boston Globe, A form of progestin, one of the hormones found in regular birth control pills, emergency contraception works most often by inhibiting ovulation and/or ...
Attempts to make morning-after pill more readily available blockedDec 26, 2005 Fort Lauderdale Sun Sentinel, The contraceptive -- two tablets containing high doses of progestin, one of the hormones in birth control pills that block ovulation and prevent sperm and egg ...
Plan B questions and answersDec 27, 2005 Sun-Sentinel.com, ...sex. It includes two pills containing a high dose. of the hormone progestin, one of the ingredients in birth control pills. Some ...
Long-term Use of Aspirin and Risk of Colorectal Cancer—ReplyDec 29, 2005 Journal of American Medical Association (subscription), 3. Chlebowski RT, Wactawski-Wende J, Ritenbaugh C, et al. Estrogen plus progestin and colorectal cancer in postmenopausal women. N Engl J Med. ...
Long-term Use of Aspirin and Risk of Colorectal CancerDec 29, 2005 Journal of American Medical Association (subscription), Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial ...
Lupus patients safe to go back on the pillDec 19, 2005 News-Medical.net, ...and also found that the flare-up rate and the severity of the flare-ups was the same whether patients got standard birth control pills, a progestin-only pill ...
New research: HRT not bad for health?Dec 21, 2005 myDNA.com, Klaiber says Prempro combines estrogen and progestin in a daily pill - a regimen that hadn't been associated with heart protection. ...
New pill changes perception of birth controlDec 19, 2005 Hagerstown Morning Herald, ...vagina. The ring stays in place for three weeks, releasing a continuous dose of estrogen and progestin to keep a woman from ovulating. ...
Herbs for menopausal comfortDec 17, 2005 Malaysia Star, ...therapy or HRT. HRT involves taking estrogen plus progestin. However, several studies have shown taking HRT has its risks. This is ...
Vitamin D: Dietary Supplement Fact SheetDec 29, 2005 Food Consumer, ...on Hormone Therapy, in American College of Obstetricians and Gynecologists Web site response to the WHI Study Results on Estrogen and Progestin Hormone Therapy ...
Home
Copyright phasechange.org 2006.
All Rights Reserved.
