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Nitrofurazone
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DRUG INFO
Nitrofurazone
Drug Name:
Nitrofurazone
Indication: For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Pharmacology: Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Mechanism Of Action: The exact mechanism of action is unknown. Nitrofurazone inhibits several bacterial enzymes, especially those involved in the aerobic and anaerobic degradation of glucose and pyruvate. This activity is believed also to affect pyruvate dehydrogenase, citrate synthetase, malate dehydrogenase, glutathione reductase, and pyruvate decarboxylase.
Drug Category: Trypanocidal Agents; Anti-Infectives
Brand Names/Synonyms: Actin-N; Aldomycin; Alfucin; Amifur; Babrocid; Becafurazone; Biofuracina; Biofurea; Chemofuran; Chixin; Cocafurin; Coxistat; Dermofural; Dymazone; Dynazone; Eldezol; Eldezol F-6; Fedacin; Flavazone; Fracine; Furacilin; Furacillin; Furacin; Furacin Soluble Dressing; Furacin Topical Cream; Furacin Topical Solution; Furacin-E; Furacin-Hc; Furacine; Furacinetten; Furacoccid; Furacort; Furacycline; Furaderm; Furagent; Furalcyn; Furaldon; Furalone; Furametral; Furan-Ofteno; Furaplast; Furaseptyl; Furaskin; Furatsilin; Furaziline; Furazin; Furazina; Furazol W; Furazone; Furazyme; Furesol; Furfurin; Furosem; Fuvacillin; Hemofuran; Ibiofural; Mammex; Mastofuran; Monafuracin; Monafuracis; Monofuracin; NF; NF-7; NFS; NFZ; NSC-2100; Nefco; Nfz Mix; Nifucin; Nifurid; Nifuzon; Nitrofural; Nitrofuraldehyde Semicarbazone; Nitrofuran; Nitrofurane; Nitrofurazan; Nitrofurazone; Nitrofurol; Nitrozone; Otofural; Otofuran; Sanfuran; Spray-Dermis; Spray-Foral; U-6421; Usaf Ea-4; Vabrocid; Vadrocid; Veterinary Nitrofurazone; Yatrocin
Dosage Forms: OINTMENT
Absorption: Well absorbed.
Interactions: Not Available
Chemical IUPAC Name: 1-amino-N-[(5-nitro-2-furyl)methylideneamino]methanamide
Chemical Formula: C6H6N4O4
Half Life: 5 hours
Drug Type: Approved Drug
# Accession No: APRD00050
CAS Registry Number: 59-87-0
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Nitrofurazone News
(When available)
Hansen's CEO confident of energy drinks' growth 15 Jan 2006
Reuters The beverage company's stock is trading at more than 30 times expected forward earnings compared with Coca-Cola Co.'s (KO.N: Quote, Profile, Research) multiple ...
COPPELL WARY OF PREMIER CHANCES 15 Jan 2006
Sportinglife.com, Steve Coppell believes Reading will struggle to adapt in the top flight should they as expected secure promotion from the Coca-Cola Championship. ...
Thommo targets play-off goal 15 Jan 2006
ic Wales, STEVEN Thompson is hoping to propel Cardiff City into the Coca Cola Championship play-offs. And the Bluebirds latest striker signing ...
Bolivia's populist president takes up the challenge of government 15 Jan 2006
Financial Times, Evo Morales's rhetoric as a presidential candidate for Bolivia was often contradictory, but the radical leader and former coca farmer struck one note of ...
LESLIE CRISS: King's dream remains a worthy goal 15 Jan 2006
Northeast Mississippi Daily Journal, ...only scant light. A bright red metal icebox filled with Coca-Colas and other soft drinks rested just under the bulb. We were offered ...
What's wrong with helping the poor? Jan 14, 2006
Elmira Star-Gazette, Evo Morales, the new democratically elected president of Bolivia, is not a demon because he supports coca farming, a major industry in Bolivia. ...
Luton new-boy eyes international chance Jan 14, 2006
eleven-a-side.com, David Bell, Luton Town’s newest signing, hopes his move to the Coca-Cola Championship side can afford him the chance to build an international career with ...
Cumbrians down to third Jan 14, 2006
Soccer365, Carlisle lost ground at the top of Coca-Cola League Two as Grimsby took second place. The Cumbrians lost 2-1 at Shrewsbury in a ...
Castro Puppet in Bolivia? Jan 13, 2006
FOX News Bolivia’s recent presidents have done well minding national accounts while US officials fretted over how much coca had been eradicated. ...
Why revolution could happen again in Peru Jan 13, 2006
Khaleej Times, But in the last few months two columns have restarted their activities in the coca producing areas in the forested Amazon region. ...
US stocks drop on share downgrades, profit jitters Jan 12, 2006
Reuters South Africa, ...and Coca-Cola Co. ... Goldman Sachs cut its rating on Coca-Cola, the world's largest soft drink maker, on expectations of lower European demand. ...
DRUGS-BOLIVIA: A New Future for Coca Leaf Jan 10, 2006
Inter Press Service (subscription), 10 (IPS) - Criminalised in the international sphere, uprooted by hoe and machete in Bolivia, but venerated by Andean indigenous cultures, the coca leaf will ...
£53m Coca-Colaplant gets all clear Jan 11, 2006
IrishExaminer.com, THE construction of a new £53 million (€77.5m) Coca-Cola plant in County Antrim has been given the go-ahead. Building work is ...
Minstermen get Parkin payback Jan 13, 2006
confguide.com, York City are set to receive a welcome financial boost following the news that former striker Jon Parkin has signed for Coca-Cola Championship outfit Hull City ...
League Announce U-21 Friendly Jan 13, 2006
Scottish Fitba, KC Stadium. The game is the first of it's kind since 1998 and the first in partnership with sponsors Coca-Cola. Having previously ...
New Coca-Cola comms director predicts busy future Jan 13, 2006
PRWeek (subscription), ATLANTA: Tom Mattia, who was named director of Worldwide Public Affairs and Communications of The Coca-Cola Company last week, expects the next few months to ...
Wolverhampton v Luton Jan 13, 2006
AsianHandicap.com, Wolves lie just outside the playoff positions in the Coca Cola Championship, picking up 39 points from their 28 games so far, with 9-W 12-D 7-L and a goal ...
Top clubs eye Guttridge Jan 13, 2006
ic Essex.co.uk, Championship sides. The 23-year-old has played a crucial part in the Blues' rise to the top of the Coca Cola League One. Premiership ...
Hartlepool v Tranmere Rovers Preview Jan 13, 2006
sportnetwork.net, As Tranmere travel to Hartlepool this weekend in Coca-Cola League One, Total Tranmere brings you all the statistics and team news to keep you in the know prior ...
Colombia Indians aim to take on Coke with coca drink Jan 3, 2006
Reuters.uk, ...using the raw material of cocaine to make a soft drink they hope will displace in their area another, better known beverage with the same ingredient: Coca-Cola ...
King and ex-coca farmer take tea Jan 4, 2006
Times Online, By Graham Keeley. Dressed in a jumper and trousers, Evo Morales, the President-elect of Bolivia and former coca farmer, took tea with King Juan Carlos of Spain. ...
Uribe vows to wipe out coca Jan 2, 2006
Daily Journal, Macarena National Park. They will not leave until they have manually eradicated every last coca plant,� he said. “The world ...
COKE BUST: ‘U’ suspends contracts with soft-drink giant Coca ... Jan 5, 2006
Michigan Daily, 29 to suspend purchasing of Coca-Cola products following the company’s failure to meet a deadline set by the University’s Dispute Review Board. ...
EU warns Bolivian leader over coca Jan 6, 2006
United Press International 6 (UPI) -- The European Union Thursday stepped up pressure on Bolivia to crack down on cocaine production and warned against expanding coca-fields for ...
Left-wing coca farmer on course to become Bolivia's president Dec 18, 2005
Scotsman, BOLIVIANS went to the polls yesterday in an election that may hand power to the country's first Indian president - a coca-leaf farmer who has called his left ...
Bolivia Coca-Growers Leader Morales Set to Win Election Today Dec 17, 2005
Bloomberg Dec. 18 (Bloomberg) -- Evo Morales, the Bolivian coca-growers leader who lost a 2002 bid for the presidency, is set to win election today on promises he will ...
Bolivia Coca-Growers Leader Morales Set to Win Vote (Update1) Dec 18, 2005
Bloomberg ...the Bolivian Indian activist who favors increased state control over the nation's natural gas reserves and opposes US efforts to ban production of coca, is set ...
Bolivia Coca-Growers Leader Morales Set to Win Vote (Update2) Dec 18, 2005
Bloomberg Indian activist Evo Morales, who favors increased state control over the nation's natural gas reserves and opposes US efforts to eradicate coca production, is ...
Bolivia Elects a President Who Supports Coca Farming Dec 18, 2005
New York Times, 18 - Evo Morales, a presidential candidate who has pledged to reverse a campaign financed by the United States to wipe out coca growing, scored a decisive ...
Bolivia Elects Leftist Ally of Coca Trade Dec 18, 2005
Los Angeles Times, LA PAZ, Bolivia — Evo Morales, a former coca farmer who has vowed to torpedo US anti-drug efforts here and be a "nightmare" for Washington, appeared set to ...
Leftist coca farmer Evo Morales poised to win Bolivian presidency Dec 19, 2005
CBC News, COCHABAMBA, Bolivia (AP) - Socialist candidate Evo Morales, who has promised to halt a US-backed campaign to end coca growing, appeared to have to won ...
Coca activist set to take Bolivian presidency Dec 19, 2005
Times Online, Bolivia was today on the verge of voting in its first Indian president, after the coca activist Evo Morales won an unexpectedly large majority in yesterday’s ...
Coca farmer may be Bolivia's next president Dec 16, 2005
Detroit Free Press, But there was nothing timid about the 46-year-old coca farmer's speech as he unleashed the kind of rhetoric that's made him one of Latin America's most talked ...
Bolivian front-runner pledges coca control Dec 20, 2005
Seattle Post Intelligencer LA PAZ, Bolivia -- Bolivia's soon-to-be president, Evo Morales, a coca farmer under pressure to crack down on cocaine, pledged Tuesday to keep controls on coca ...
Apparent victor in Bolivia vows to end anti-coca program Dec 19, 2005
Houston Chronicle, The leftist who claimed victory in Bolivia's presidential race on Monday repeated his promise to end a US-backed program to eradicate coca plants, saying the ...
Celebrating likely victory, Morales repeats vow to kill anti-coca ... Dec 19, 2005
San Diego Union Tribune, Bolivia – The Socialist firebrand who claimed victory in Bolivia's presidential race repeated his promise to end a US-backed crusade against coca plants, but ...
Bolivian Front-Runner Pledges Coca Control Dec 20, 2005
ABC News Buyers trade coca leaves on a coca market in La Paz, Bolivia on Friday, Jan. 23, 2004. Bolivia's future president Evo Morales, under ...
Legalization of coca concerns US Dec 20, 2005
Miami Herald, Bolivia's election results could end strife in the country, but it could also mean more production of coca, the raw ingredient in cocaine. ...
Bolivia Leader Won't OK Coca Eradication Dec 29, 2005
ABC News Wearing a wreath of coca leaves, Bolivia's president-elect Evo Morales waves to supporters during a visit to Eterazama, in the coca growing region of Chapare ...
Bolivian Front-Runner Seeks Coca Control Dec 20, 2005
Houston Chronicle, LA PAZ, Bolivia — Bolivia's presidential front-runner said Tuesday he would not allow unlimited production of coca, the crop used to produce cocaine, but ...
Bolivia might reject US aid over coca Dec 29, 2005
San Jose Mercury News, LA PAZ, Bolivia - President-elect Evo Morales will reject US economic and military aid if the United States requires continued coca-eradication efforts to get ...
Bolivia Leader Won't OK Coca Eradication Dec 29, 2005
Houston Chronicle, ETERAZAMA, Bolivia — President-elect Evo Morales traveled to the heart of Bolivia coca-growing region to reinforce a campaign theme: he will not permit the ...
Morales pledges to control coca production Dec 20, 2005
Independent Online, La Paz, Bolivia - Bolivia's future president Evo Morales, a coca producer under pressure to crack down on cocaine, pledged to keep controls on coca but said he ...
Bolivia's future leader pledges to control coca Dec 20, 2005
Mail & Guardian Online, Bolivia's future president Evo Morales, a coca producer under pressure to crack down on cocaine, has pledged to keep controls on coca but says he will study ...
Morales vows to defend coca growers Dec 18, 2005
CCTV, Final official results have not yet been announced. The front-runner is vowing to bring socialism and legalize coca growing. The ...
In Bolivia, a setback for US anti-coca drive Dec 21, 2005
ABC News Mr. Morales campaigned on the promise of decriminalizing coca. This ... projects. Morales's stance on coca may also have regional ramifications. ...
Defiant Bolivia clashes with US over coca crops Dec 15, 2005
Scotsman, Bolivian coca cultivation is still associated with the southern Bolivian Chapare region, which provided the basic ingredient for almost half the world's ...
Update 1: Bolivian Front-Runner Seeks Coca Control Dec 20, 2005
Forbes Bolivia's presidential front-runner said Tuesday he would call a referendum on how to control the production of coca, the crop used to produce cocaine as well ...
Bolivian Front-Runner Seeks Coca Control Dec 20, 2005
Houston Chronicle, LA PAZ, Bolivia — Bolivia's presidential front-runner said Tuesday he would call a referendum on how to control the production of coca, the crop used to ...
Bolivian Front-Runner Pledges Coca Control Dec 20, 2005
ABC News Freddy Pari, 40, picks coca seeds to sell on a street market in the village of La Asunta, some 200 km (124 miles) east of Bolivian capital La Paz on Sunday ...
Morales: Coca controls to stay Dec 21, 2005
Miami Herald, Evo Morales, the next president of Boliva and a coca grower, said his administration will continue to control legal cultivation of the plant. BY FIONA SMITH. ...
Bolivia coca crusade may bump into harsh reality Dec 21, 2005
Reuters AlertNet, LA PAZ, Bolivia, Dec 21 (Reuters) - President-elect Evo Morales' pledge to protect coca crops to help Indians, who celebrate the leaves as a centerpiece of ...
Socialist coca farmer elected president in Bolivia Dec 19, 2005
Lexington Herald Leader, ...has made international headlines with his bold attacks on Washington-backed policies such as free trade agreements and the eradication of coca leaf, the main ...
New leader of Bolivia: Zero cocaine, not zero coca Dec 21, 2005
Chicago Sun-Times, LA PAZ, Bolivia -- Bolivia's soon-to-be president said Tuesday he would not allow unlimited production of coca, the crop used to produce cocaine. ...
Coca fan romps home in Bolivia Dec 18, 2005
Buenos Aires Herald (subscription), Colombia and Peru. Morales wants to end the US-funded eradication of coca, the crop used to make cocaine. Morales’ indigenous ...
Bolivia coca crusade may antagonize US Dec 21, 2005
ABC News A Bolivian coca buyer (R) checks the quality of leaves at a market 350 miles east of La Paz, December 18, 2005. REUTERS/Rickey Rogers. ...
Bolivia coca crusade may bump into harsh reality Dec 21, 2005
Stuff.co.nz, BOLIVIA: President-elect Evo Morales' pledge to protect coca crops to help Indians, who celebrate the leaves as a centerpiece of their ancient culture, could ...
Next Bolivian Leader Pledges Coca Control Dec 21, 2005
ABC News Bolivia's caretaker government on Tuesday prepared to hand over power to Evo Morales, the leftist coca-grower who will be the Andean nation's first Indian ...
Bolivian activist wins presidency Morales pledges to maintain coca ... Dec 19, 2005
Waterbury Republican American, Morales campaigned against US efforts to eradicate production of coca and vowed to increase state control of the nation's natural-gas reserves, the largest in ...
EU to pay for study of coca in Bolivia Dec 24, 2005
Miami Herald, President-elect Evo Morales persuaded the European Union to fund a study to track what happens to Bolivia's coca leaf and how much is used in the drug trade. ...
11:54 am: Leftist coca farmer poised to win Bolivian presidency Dec 19, 2005
Santa Fe New Mexican, Raucous celebrations erupted among supporters of the coca-farming activist as some independent vote counts on Monday showing Morales getting a clear majority ...
Coca Farmer Brings Hope for Bolivian Reform Dec 19, 2005
Drug Policy Alliance, Bolivia's drug policy may undergo a dramatic transformation now that coca farmer Evo Morales has won the country's presidential election. ...
EU to finance Bolivia's study on coca at new Bolivian president's ... Dec 23, 2005
People's Daily Online, The European Union (EU) will finance a study in Bolivia to determine what proportion of the coca leaves grown there should go to manufacturing cocaine and what ...
Colombians kill soldiers on coca mission Dec 27, 2005
The Age, Marxist rebels have killed 24 Colombian soldiers on a mission to destroy coca plants, the worst blow against the military for years as tensions rise ahead of ...
Colombian rebels kill 28 soldiers on coca mission Dec 27, 2005
Reuters BOGOTA, Colombia (Reuters) - Marxist rebels killed 28 Colombian soldiers on a mission to destroy coca plants on Tuesday, the worst blow against the military ...
Colombian rebels kill 24 soldiers on coca mission Dec 27, 2005
Reuters AlertNet, BOGOTA, Colombia, Dec 27 (Reuters) - Marxist rebels killed 24 Colombian soldiers on a mission to destroy coca plants on Tuesday, the worst blow against the ...
'Coca Is the Tree of the Poor': Indigenous People Leap Forward in ... Dec 20, 2005
New California Media, By any measure, Bolivians made history Sunday with their overwhelming vote to make Evo Morales, an Aymara Indian and leader of the nation's coca leaf growers ...
Coca farmer is elected Bolivia’s new president Dec 19, 2005
Columbia Daily Tribune, COCHABAMBA, Bolivia (AP) - Socialist candidate Evo Morales, who has promised to halt a US-backed campaign to end coca growing, appeared to have won Bolivia’s ...
'Mother Coca' Wins in Bolivia -- Can Evo Morales Foster World Coca ... Dec 21, 2005
Pacific News Service, Editor's Note: Advocates of coca, which can be manufactured into cocaine but has been grown and chewed in the Andes for millennia, hope that indigenous leader ...
Coca-leaf beverage packs extra lift in each mouthful Dec 15, 2005
Seattle Times, By SERGIO DE LEON. BOGOT�, Colombia — A new soft drink made in Colombia may not be cola, but it's definitely coca. A Nasa Indian ...
Socialist coca-grower set to take power in Bolivia Dec 19, 2005
WOI, COCHABAMBA, Bolivia The man who's the unofficial winner in the Bolivian presidential race is repeating his promise to end the fight against coca plants -- a ...
Coca Farmer Wins Bolivian Election: New President to Challenge ... Dec 29, 2005
CorpWatch.org, ...because he is one of them. He is proudly indigenous, he is a former coca farmer, and he is the son of a tin miner. For a model of what ...
US Opposes 'Pro-Coca' Candidate's Victory In Bolivia Dec 15, 2005
All Headline News Washington, DC (AHN) - The United States say they will evaluate its political relationship with Bolivia as a Sunday election put "pro-coca leaf" candidate, Evo ...
Colombia sells coca-leaf soda Dec 21, 2005
Christian Science Monitor, Monitor. BOGOT�, COLOMBIA – Forget Coca-Cola, a group of Colombian Indians is telling its community. Drink the real thing: coca. ...
Bolivia's apparent president-elect pledges to control coca Dec 20, 2005
Pravda, Bolivia's apparent president-elect, Evo Morales, said Tuesday he would not allow unlimited production of coca, the crop used to produce cocaine, but would also ...
Uribe declares war on coca after attack Dec 29, 2005
Miami Herald, The Colombian president vowed to crush coca production after a deadly attack by 'narco' rebels that killed 29 soldiers. BY JOSHUA GOODMAN. ...
Colombia Leader Plans Coca Eradication Effort Dec 29, 2005
Los Angeles Times, BOGOTA, Colombia — President Alvaro Uribe said Wednesday that workers would destroy all coca plants around one of Colombia's largest national parks, where 29 ...
Colombia vows crackdown on coca Dec 29, 2005
BBC News, Colombia's president has vowed to destroy every coca plant in the region where 29 soldiers died in one of the worst rebel attacks in recent years. ...
Colombia's President Vows to Eradicate Coca Plants Dec 28, 2005
Voice of America President Uribe Wednesday said the government will not rest until "the last coca plant" is eradicated near Macarena National Park, in an operation beginning ...
PCB, Furan Exposure Increases Risk of Non-Hodgkin's Lymphoma Dec 15, 2005
Cancerpage.com, Each of the furan congeners examined was associated with an increased risk of non-Hodgkin's lymphoma, the results indicate, ranging from 1.8- to 2.6-fold per ...
What's that smell? It could be someone burning trash illegally Jan 14, 2006
Durham Herald Sun, Open burning of garbage can release as much dioxin and furan, chemicals known to cause long-term health problems, as one regulated incinerator that burns ...
Smoking ban enforcement blasted Dec 23, 2005
Great Falls Tribune, But Darrell Furan, an environmental scientist with the department, said the county has not investigated the alleged violations. ...
Restaurant owner complains Cascade County not enforcing smoking ... Dec 23, 2005
Billings Gazette, ...the law. "We're still just educating," said Darrell Furan, an environmental scientist with the county health department. Three complaints ...
Dow fined for conducting unreported dioxin tests Jan 6, 2006
Midland Daily News (subscription), ...that the state and The Dow Chemical Company have reached a settlement and signed a consent order stemming from unapproved, unreported dioxin and furan testing. ...
ASHLAND: Ashland Castings Solutions Expands to India Jan 6, 2006
Webbolt Business News (subscription), The initial offering of Ashland casting products will include ISOCURE(R) cold box binders, PEPSET(R) no-bake binders, furan no-bake binder technology and a ...
Ashland Castings Solutions Expands to India Jan 5, 2006
PR Newswire (press release), ...with our customers there." The initial offering of Ashland casting products will include ISOCURE(R) cold box binders, PEPSET(R) no-bake binders, furan no-bake ...
A look at the rest of the races Jan 4, 2006
Janesville Gazette, W. Miles Road, Janesville. Municipal Judge: Robert Furan, 26 Pine Cone Court, Edgerton, runs uncontested. Mayor: Incumbent Mike ...
Gov’t asked to help improve smoked tuna prod’n Dec 27, 2005
Minda News, ...of the locally produced smoked tuna in the EU market could be due to the ban on the so-called "dirty dozen" substances which include dioxin and furan. ...
Finland invests further EUR 2.5 mln into Nordic carbon finance ... Dec 30, 2005
Newsroom Finland, ...it had invested 2.5 million euros into the Testing Ground Facility (TGF), the carbon finance instrument of the Nordic Environment Finance Corporation (Nefco). ...
ECGC cover likely for shrimp consignments Jan 1, 2006
Financial Express, Strict and new norms to screen the shrimp consignments for presence of residues of banned anti-biotics like chloramphenicol and nitrofuran metabolies had ...
EU rapid alert finds mercury in Greenland halibut from the Russian ... Dec 21, 2005
Fishupdate.com, The unathorised substance nitrofuran (metabolite)-furazolidone (AOZ) was detected in whole shrimps from Ecuador, notified by the Netherlands. ...
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