|
Nitrofurantoin
resources
|
|
|
|
|
|
DRUG INFO
Nitrofurantoin
Drug Name:
Nitrofurantoin
Indication: For the treatment of infection (urinary tract)
Pharmacology: Nitrofurantoin, a nitrofuran antibacterial agent, is available in microcrystalline and macrocrystalline form to treat urinary tract infections caused by many gram-negative and some gram-positive bacteria.
Mechanism Of Action: Nitrofurantoin inhibits bacterial acetyl-coenzyme A, interfering with the organism's carbohydrate metabolism. The drug also can disrupt bacterial cell wall formation.
Drug Category: Anti-Infectives; Anti-Infectives; ATC:J01XE01
Brand Names/Synonyms: Alfuran; Apo-Nitrofurantoin; Benkfuran; Berkfurin; Ceduran; Chemiofuran; Cistofuran; Cyantin; Cystit; Dantafur; Fua Med; Fuamed; Fur-Ren; Furabid; Furachel; Furadantin; Furadantin Retard; Furadantina Mc; Furadantine; Furadantine Mc; Furadantine-Mc; Furadantoin; Furadoin; Furadoine; Furadonin; Furadonine; Furadontin; Furalan; Furaloid; Furan; Furanite; Furantoin; Furantoina; Furatoin; Furedan; Furina; Furobactina; Furophen T; Furophen T-Caps; Gerofuran; It-Uran; Ituran; Ivadantin; Macpac; Macrobid; Macrodantin; Macrodantina; Macrofuran; Macrofurin; N-Toin; NSC-2107; Nierofu; Nifurantin; Nitoin; Nitrex; Nitrofan; Nitrofur-C; Nitrofuradantin; Nitrofurantoin; Novo-Furantoin; Novofuran; Orafuran; Parfuran; Phenurin; Ro-Antoin; Siraliden; Trantoin; Uerineks; Upiol; Urantoin; Urizept; Uro-Selz; Uro-Tablinen; Urodin; Urofuran; Urofurin; Urolisa; Urolong; Usaf Ea-2; Uvaleral; Welfurin; Zoofurin
Dosage Forms: TABLET
Absorption: Not Available
Interactions:
DrugBank: Interactions for Nitrofurantoin
Interactions for Nitrofurantoin:
Antacids containing magnesium trisilicate, when administered concomitantly with nitrofurantoin, reduce
both the rate and extent of absorption. The mechanism for this interaction probably is adsorption of nitrofurantoin
onto the surface of magnesium trisilicate.
Uricosuric drugs, such as probenecid and sulfinpyrazone, can inhibit renal tubular secretion of
nitrofurantoin. The resulting increase in nitrofurantoin serum levels may increase toxicity, and the decreased
urinary levels could lessen its efficacy as a urinary tract antibacterial.
Drug/Laboratory Test Interactions
As a result of the presence of nitrofurantoin, a false-positive reaction for glucose in the urine may
occur. This has been observed with Benedictís and Fehlingís solutions but not with the glucose
enzymatic test.
Chemical IUPAC Name: 1-[(5-nitro-2-furyl)methylideneamino]imidazolidine-2,4-dione
Chemical Formula: C8H6N4O5
Half Life: 0.3-1 hour.
Drug Type: Approved Drug
# Accession No: APRD00191
CAS Registry Number: 67-20-9
|
|
|
|
|
|
Nitrofurantoin News
(When available)
PCB, Furan Exposure Increases Risk of Non-Hodgkin's Lymphoma Dec 15, 2005
Cancerpage.com, Each of the furan congeners examined was associated with an increased risk of non-Hodgkin's lymphoma, the results indicate, ranging from 1.8- to 2.6-fold per ...
What's that smell? It could be someone burning trash illegally Jan 14, 2006
Durham Herald Sun, Open burning of garbage can release as much dioxin and furan, chemicals known to cause long-term health problems, as one regulated incinerator that burns ...
Smoking ban enforcement blasted Dec 23, 2005
Great Falls Tribune, But Darrell Furan, an environmental scientist with the department, said the county has not investigated the alleged violations. ...
Restaurant owner complains Cascade County not enforcing smoking ... Dec 23, 2005
Billings Gazette, ...the law. "We're still just educating," said Darrell Furan, an environmental scientist with the county health department. Three complaints ...
Dow fined for conducting unreported dioxin tests Jan 6, 2006
Midland Daily News (subscription), ...that the state and The Dow Chemical Company have reached a settlement and signed a consent order stemming from unapproved, unreported dioxin and furan testing. ...
ASHLAND: Ashland Castings Solutions Expands to India Jan 6, 2006
Webbolt Business News (subscription), The initial offering of Ashland casting products will include ISOCURE(R) cold box binders, PEPSET(R) no-bake binders, furan no-bake binder technology and a ...
Ashland Castings Solutions Expands to India Jan 5, 2006
PR Newswire (press release), ...with our customers there." The initial offering of Ashland casting products will include ISOCURE(R) cold box binders, PEPSET(R) no-bake binders, furan no-bake ...
A look at the rest of the races Jan 4, 2006
Janesville Gazette, W. Miles Road, Janesville. Municipal Judge: Robert Furan, 26 Pine Cone Court, Edgerton, runs uncontested. Mayor: Incumbent Mike ...
Gov’t asked to help improve smoked tuna prod’n Dec 27, 2005
Minda News, ...of the locally produced smoked tuna in the EU market could be due to the ban on the so-called "dirty dozen" substances which include dioxin and furan. ...
Ituran Location and Control Ltd.: Filing of a Lawsuit in Israel ... Dec 19, 2005
Yahoo! News (press release) AZOUR, Israel, December 19 /PRNewswire-FirstCall/ -- Ituran Location and Control Ltd. (NASDAQ: ITRN, TASE: ITRN), announced that ...
Ituran Location and Control Ltd.: Filing of a Lawsuit in Israel ... Dec 19, 2005
Autochannel AZOUR, Israel, December 19 -- Ituran Location and Control Ltd. , announced that yesterday - December 18, 2005, it was served with ...
LoJack's Stronger Signal Jan 13, 2006
BusinessWeek ...$21.8 million, up 26%. Rivals are racing to catch LoJack's lead. Ituran Location & Control Ltd. (ITRN ), an Israeli company with ...
Fueling the partnership Jan 5, 2006
Ha'aretz (subscription), ..."I asked where he was and was told that he had gone for a walk with Rajoub's children." Ezra says he met Koko when he, Ezra, was CEO of Ituran, a company that ...
(PRN) - Immucor, Inc. Announces Appointment of Chief Financial ... Dec 19, 2005
Bolsamania.com, Science Journals ... [+. PRN) - Ituran Location and Control Ltd.: Filing of a Lawsuit in Israel Against Ituran ... [+. PRN) - Tibotec ...
Stocks Rise A Bit In Sleepy Session Dec 22, 2005
Investor's Business Daily (subscription) ...quarters. Recent new issue Ituran Location & Control (ITRN), featured today in IBD, hit an all-time, rising 81 cents to 16.33. The ...
Stocks Nab Gains As Volume Recedes Dec 22, 2005
Investor's Business Daily (subscription) Recent new issue Ituran Location & Control (ITRN), featured today in IBD, hit an all-time, rising 1.13 to 16.65 in nearly double its normal volume. ...
Sun: UBS recommendation boosts Hapoalim 1.6% Dec 25, 2005
Globes, 6.2%, probably helped by the rise in Bank Hapoalim. Ituran Location and Control responded to rises on Wall Street with a 3.2% rise.
“TA 25 could hit 1000 in 2006� Dec 15, 2005
Globes, ...acquisition. “Ituran Location and Control Ltd. (Nasdaq:ITRN); TASE:ITRN) is a company that will continue to grow in the coming years. ...
Macpac Epic 150 SF Sleeping Bag REVIEW Dec 13, 2005
Backpacking Light (subscription), ...home...". BY Will Rietveld. The Macpac Epic 150 SF sleeping bag has a lightweight Pertex Endurance shell and is fully seam taped. It ...
Six NJ mechanical trades unions create statewide council Jan 5, 2006
philly.com, ...high degree of skill. The group, which is self-funded, will also have a political action committee, MACPAC. The six unions involved ...
Actis sells trading unit of Nitrex Chem Dec 19, 2005
Sify, New Delhi: Private equity player Actis has sold the trading division of Nitrex Chemicals, a major player in the domestic nitrocellulose market, to EAC ...
Actis to sell Nitrex int'l trading arm to Thai's EAC Dec 19, 2005
Economic Times, Sources close to the development said Nitrex Chemicals India, the company which was formed to take over the nitrocellulose and international trading businesses ...
Clamps for European press brakes improved Jan 11, 2006
Manufacturing Talk, Manual clamps for European style press brakes aree coated with Nitrex, which ensures that the location faces do not become scratched or bruised during the ...
Wood chips keep nitrogen in check Dec 21, 2005
Upper Cape Codder, Lombardo Associates holds exclusive rights to the NITREX permeable reactive barrier, patented by the University of Waterloo in Ontario. ...
ECGC cover likely for shrimp consignments Jan 1, 2006
Financial Express, Strict and new norms to screen the shrimp consignments for presence of residues of banned anti-biotics like chloramphenicol and nitrofuran metabolies had ...
EU rapid alert finds mercury in Greenland halibut from the Russian ... Dec 21, 2005
Fishupdate.com, The unathorised substance nitrofuran (metabolite)-furazolidone (AOZ) was detected in whole shrimps from Ecuador, notified by the Netherlands. ...
|
|
|
