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Methylphenidate
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DRUG INFO
Methylphenidate
Drug Name:
Methylphenidate
Indication: Children with attention deficit disorders
Pharmacology: Methylphenidate, a central nervous system stimulant chemically similar to the amphetamines, is used to treat narcolepsy, attention-deficit hyperactivity disorder (ADHD) in children, post-stroke depression or other depressive disorders.
Mechanism Of Action: Methylphenidate blocks dopamine uptake in central adrenergic neurons by blocking dopamine transport or carrier proteins. Methylphenidate acts at the brain stem arousal system and the cerebral cortex and causes increased sympathomimetic activity in the central nervous system. Alteration of serotonergic pathways via changes in dopamine transport may result.
Drug Category: Adrenergic Agents; Dopamine Agents; Central Nervous System Agents; Anorexigenic Agents; Stimulants; ATC:N06BA04
Brand Names/Synonyms: 4311/B Ciba; C 4311; CHEMBANK1663; Calocain; Centedein; Centedrin; Centedrine; Centredin; Concerta; Dea No. 1724; Focalin; Focalin Xr; HSDB 3126; METHYLPHEN; Meridil; Metadate; Metadate Cd; Metadate Er; Methyl Phenidyl Acetate; Methylin; Methylin Er; Methylofenidan; Methylphenidan; Methylphenidate; Methylphenidate Hcl; Methylphenidate Hydrochloride; Methylphenidatum [Inn-Latin]; Methylphenidylacetate Hydrochloride; Methypatch; Metilfenidat Hydrochloride; Metilfenidato [Inn-Spanish]; Metilfenidato [Italian]; Phenidylate; Plimasine; Pms-Methylphenidate; Riphenidate; Ritalin; Ritalin Hydrochloride; Ritalin La; Ritalin Sr; Ritalin-Sr; Ritaline; Ritcher Works
Dosage Forms: Tablets, SR tablets
Absorption: readily absorbed in a biphasic manner. It reaches peak absorption at approximately two hours for the first phase and five hours for the second phase. bioavailability is low (approx. 30%)
Interactions:
DrugBank: Interactions for Methylphenidate
Interactions for Methylphenidate:
Ritalin may decrease the hypotensive effect of guanethidine. Use cautiously with pressor agents.
Human pharmacologic studies have shown that Ritalin may inhibit the metabolism of coumarin anticoagulants,
anticonvulsants (phenobarbital, diphenylhydantoin, primidone), phenylbutazone, and tricyclic drugs (imipramine,
clomipramine, desipramine). Downward dosage adjustments of these drugs may be required when given concomitantly with
Ritalin.
Serious adverse events have been reported in concomitant use with clonidine, although no causality for the
combination has been established. The safety of using methylphenidate in combination with clonidine or other
centrally acting alpha-2 agonists has not been systemically evaluated.
Chemical IUPAC Name: methyl2-phenyl-2-(2-piperidyl)ethanoate
Chemical Formula: C14H19NO2
Half Life: 2.4 hours in children and 2.1 hours in adults
Drug Type: Approved Drug
# Accession No: APRD00657
CAS Registry Number: 113-45-1
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Methylphenidate News
(When available)
ADHD drug may help hyperactive teens Jan 13, 2006
Reuters NEW YORK (Reuters Health) - Adolescents with attention-deficit/hyperactivity disorder (ADHD) respond well to treatment with Concerta, a once-daily extended ...
ADHD drug may help hyperactive teens Jan 13, 2006
Independent Online, New York - Adolescents with attention-deficit/hyperactivity disorder (ADHD) respond well to treatment with Concerta, a once-daily extended-release form of the ...
Club-goer arrested after grabbing cop Jan 14, 2006
Savannah Morning News, Police identified the pills as diet drug Phentermine and three medications used to treat Attention Deficit Disorder: Ritalin, Adderall and Concerta. ...
UB researcher helping Japan implement ADHD programs Jan 5, 2006
University at Buffalo Reporter, ..."ADHD medication is just beginning to be used in Japan," says Pelham, who helped develop Concerta and who has conducted many other trials involving other ...
ADHD Drugs Are Generally Safe, Some Doctors Say Ahead of FDA Panel Jan 6, 2006
Medscape (subscription) Drugs currently available to treat ADHD are methylphenidates, which include Johnson & Johnson's Concerta and Novartis AG's Ritalin and Focalin, and amphetamines ...
Deaths Among Attention-Deficit Drug Patients to Get US Review Jan 3, 2006
Bloomberg A panel of FDA advisers told the agency at a June 2005 meeting that Johnson & Johnson might need to clarify heart warnings for its Concerta attention-deficit ...
FDA to probe ADHD drug safety Jan 5, 2006
Pharma Times (subscription), ...an investigation into the safety of ADHD products based on the stimulant drug methylphenidate, including Johnson & Johnson's once-daily Concerta product, and ...
Research Examines Effect of Enzymotec Product on Children's ... Jan 10, 2006
NPIcenter (press release), The use of ADHD drugs (mainly Ritalin and Concerta) is strongly criticized by parents who resent their sedative effect and fear that it will have a negative ...
Unintentional violation still haunts Sportswoman of Year Jan 4, 2006
Indianapolis Star, She disclosed then she had taken Concerta, a medication for attention deficit hyperactivity disorder. But because she did not have ...
ADD Drugs' Link to Deaths, Heart Attacks Gets Review (Update1) Jan 3, 2006
Bloomberg Concerta is a once-daily form of Ritalin, a generic medicine that a parent company of Novartis AG pioneered in the 1950s. Adderall contains amphetamine. ...
Nation Briefs Jan 4, 2006
New York Times, Few mental health experts say widely prescribed attention disorder drugs, which include Ritalin, Concerta and Adderall, are dangerous, but scattered reports of ...
The Ratings Game JP Morgan ups J&J rating Jan 3, 2006
MarketWatch JP Morgan analyst also said he thinks the market has not completely factored in possible delays in generic competition for Ditropan and Concerta, two leading ...
ADHD Drug Cardiac Events, COX-2s Are Topics For Drug Safety ... Jan 5, 2006
FDA Advisory Committee In June, FDA’s Pediatric Advisory Committee concluded that reports of suicidality with Johnson & Johnson’s Concerta and other methylphenidate products used ...
Booms and busts mark business year Jan 1, 2006
TheReporter.com, Alza - which develops drug delivery systems as well as pharmaceuticals including Concerta and Nicoderm CQ - was founded in 1968, and opened its Vacaville ...
Medicating kids Dec 18, 2005
Sioux Falls Argus Leader, Some drugs changed his eating patterns, and some made it difficult to sleep. Two years ago, Trent finally found a drug that fit - Concerta. ...
ADHD Medication: Ritalin Patch Will Break Down Barriers to ... Dec 21, 2005
Emediawire (press release), ...the same as the side effects which are possible with the oral form of the medication -- available in preparations such as Ritalin LA, Concerta, and Metadate CD ...
ADHD Options Dec 21, 2005
WFtv.com, The medications that seem to be the most effective are a class of drugs known as stimulants. These include: Ritalin, Adderall, Concerta, and Focalin. ...
Community Calendar Dec 19, 2005
Fitchburg Sentinel, For information, call (978) 582-6572. Handbell Concerta concert: 7 pm, Pilgrim Congregational Church, 26 West St., Leominster. A ...
Salisbury Police Arrest Two People In Drug Bust Dec 21, 2005
WSOCtv.com, As a result of the search, officers seized Hydrocodone, Loritabs, Klonopin, Oxycodone, Xanax, Valium, Lorecet, Concerta, Methodone, and Clonazepan. ...
DOV Pharmaceutical, Inc. Appoints Scott Myers to Senior Vice ... Dec 14, 2005
Yahoo! News (press release) Most recently, he was General Manager of McNeil Specialty Pharmaceuticals, where he had overall P&L responsibility, managed the Concerta® and Flexeril ...
Celgene Corporation Reviews Recent Highlights and Outlines 2006 ... Jan 9, 2006
MSN Money ...was attributed to growing product revenue and profits supported by multiple product revenue streams including, THALOMID(R), ALKERAN(R), FOCALIN XR(TM) and the ...
Bellaire man faces charges in heist Jan 11, 2006
Martins Ferry Times Leader, ...well as a PlayStation 2, 10 games, a black purse containing birth certificates, Social Security cards, shot records, and two prescriptions for Zanax and Focalin ...
Celgene Corporation Reviews Recent Highlights and Outlines 2006 ... Jan 9, 2006
Yahoo! News (press release) ...performance was attributed to growing product revenue and profits supported by multiple product revenue streams including, THALOMID®, ALKERAN®, FOCALIN XR(TM ...
ADHD Drugs Are Generally Safe, Some Doctors Say Ahead of FDA Panel Jan 6, 2006
Medscape (subscription) Drugs currently available to treat ADHD are methylphenidates, which include Johnson & Johnson's Concerta and Novartis AG's Ritalin and Focalin, and amphetamines ...
ADHD Options Dec 21, 2005
WFtv.com, The medications that seem to be the most effective are a class of drugs known as stimulants. These include: Ritalin, Adderall, Concerta, and Focalin. ...
Ritalin Conjugate Used to Treat "Chemo-Brain" in Breast Cancer ... Dec 13, 2005
DG News The methylphenidate formulation used is an enantiomer of racemic Ritalin, known as Focalin, which has also been approved in the US for the treatment of ...
Celgene Corporation Reviews Recent Highlights and Outlines 2006 ... Jan 9, 2006
MSN Money ...was attributed to growing product revenue and profits supported by multiple product revenue streams including, THALOMID(R), ALKERAN(R), FOCALIN XR(TM) and the ...
GUAM: Ice Epidemic Sweeps Guam 16 Jan 2006
Pacific Magazine, Pacific Daily News reports that since November, Guam Customs and Quarantine has seized more than $2 million worth of methamphetamine hydrochloride, the drug ...
Truck overturns, spilling hydrochloride, forcing some evacuations Dec 15, 2005
Times Daily, Some Daphne businesses near the Interstate 10 exit were temporarily evacuated Thursday after a truck overturned, spilling hydrochloride. ...
Truck overturns, spills hydrochloride Dec 16, 2005
Montgomery Advertiser, DAPHNE -- Some Daphne businesses near the Interstate 10 exit were evacuated temporarily Thursday after a truck overturned, spilling hydrochloride. ...
Eisai Receives Confirmation that Aricept (donepezil hydrochloride) ... Dec 27, 2005
Japan Corporate News (press release), Tokyo, Japan, Dec 27, 2005 - (JCN Newswire) - Eisai Co., Ltd. (TSE: 4523) announced that its UK subsidiary, Eisai Ltd., has received ...
Eisai Receives Confirmation that Aricept (donepezil hydrochloride) ... Dec 27, 2005
Asia Corporate News Network (press release), ...(via ACN Newswire) - Tokyo, Japan, Dec 27, 2005 - (JCN Newswire) - Eisai Co., Ltd. (TSE: 4523) announced that its UK subsidiary, Eisai ...
PLIVA Announces Tentative Approval for Sertraline Hydrochloride ... Dec 23, 2005
Biotech Intelligence (press release), Food and Drug Administration ("FDA") has granted tentative approval for its Abbreviated New Drug Application ("ANDA") for Sertraline Hydrochloride tablets, 25 ...
Eisai Receives Confirmation That Aricept (donepezil Hydrochloride) ... Dec 27, 2005
PharmaLive.com (press release), TOKYO, Dec. 27, 2005-Eisai Co., Ltd. (Headquarters: Tokyo, President: Haruo Naito) announced that its UK subsidiary, Eisai Ltd. ...
Black-market bird flu drug seized in raids Jan 14, 2006
The Sunday Times, One British firm was last week offering on its website a cheaper, less effective antiviral drug called Amantadine Hydrochloride and calling it Tamiflu. ...
2 Maranaos face drug transport rap Jan 13, 2006
Sun.Star, ...shabu. The materials taken from the suspects were tested positive for Methamphetamine Hydrochloride or commonly known as shabu. ...
Eisai Receives Confirmation that Aricept (donepezil hydrochloride) ... Dec 27, 2005
TMCnet ...(Comtex Business)Tokyo, Japan, Dec 27, 2005 (JCN Newswire via COMTEX) --Eisai Co., Ltd. (TSE: 4523) announced that its UK subsidiary ...
Aricept (donepezil Hydrochloride), Orodispersible Tablet ... Dec 29, 2005
Medical News Today (press release), Tokyo, Japan, (JCN Newswire) - Eisai Co., Ltd (TSE: 4523) announced that its UK subsidiary, Eisai Ltd, has received notification of the completion of the ...
Seized jeans impregnated with cocaine Jan 13, 2006
Irish Medical News, ...was detained at Dublin airport on suspicion of smuggling illegal substances, and was later found to have been carrying around 865g of cocaine hydrochloride. ...
New Study Suggests Cymbalta (Duloxetine Hydrochloride) Reduced ... Dec 13, 2005
DG News INDIANAPOLIS, IN -- December 13, 2005 -- Cymbalta(R) (duloxetine hydrochloride) reduced symptoms of depression at least as fast as Lexapro(R) (escitalopram) by ...
Do the math: Same drugs, lower price Jan 15, 2006
Boston Globe, For example, Metformin hydrochloride, a diabetes drug, cost $18 at Johnson compared with $88.19 at Walgreens and $85.59 at CVS at the same quantity and ...
Genzyme Reports 22 Percent Increase in Fourth-Quarter Revenue Jan 9, 2006
MSN Money Fourth-quarter revenue for Renagel(R) (sevelamer hydrochloride), a phosphate binder for patients with end-stage kidney disease on hemodialysis, grew 12 percent ...
Sepracor Receives Notice of Second Abbreviated New Drug ... Jan 12, 2006
Business Wire (press release), FDA) has received an abbreviated new drug application (ANDA) from Dey, LP for a generic version of levalbuterol hydrochloride inhalation solution. ...
McDermott´s 2005 Top 10 Life Science Decisions Jan 10, 2006
Mondaq News Alerts, ...to the Hatch-Waxman Amendments to the Federal Food, Drug and Cosmetic Act, seeking approval to market its generic version of the drug sertraline hydrochloride. ...
Sepracor to defend Xopenex Jan 12, 2006
MetroWest Daily News, ...maker Merck KGaA, had filed a generic drug application with the Food and Drug Administration for a version of inhalable levalbuterol hydrochloride, the active ...
Cops, NBI raid idle ‘shabu lab’ Jan 13, 2006
Sun.Star, ...an empty warehouse in Barangay Pulpogan, Consolacion, Cebu were equipment units essential to the manufacture of methamphetamine hydrochloride, commonly known ...
Arch Chemicals Reports that Studies Confirm that Vantocil(TM) ... Jan 13, 2006
Business Wire (press release), ...environments is impractical. VANTOCIL(TM) is based on the active ingredient poly (hexamethylenebiguanide) hydrochloride (PHMB). The PHMB ...
Local news Jan 10, 2006
Pacific Daily News, In a plea agreement, Cole pleaded guilty to conspiracy to distribute more than 92 grams of methamphetamine hydrochloride from Mexico to California to Hawaii to ...
City Councilman resigns Jan 12, 2006
Myrtle Beach Sun News, ...and July 5. Those drugs included hydrocodone, marijuana, OxyContin, Zyrtec 10, buspirone hydrochloride and ranitidine. He also is ...
Sepracor Receives Notice of Second Abbreviated New Drug ... Jan 12, 2006
Finanzen.net, Administration (FDA) hasreceived an abbreviated new drug application (ANDA) from Dey, LP fora generic version of levalbuterol hydrochloride inhalation solution ...
Protein Design Labs Becomes PDL BioPharma Jan 9, 2006
MSN Money The company now markets Cardene(R) IV (nicardipine hydrochloride) for short-term treatment of hypertension when oral therapy is not feasible or desirable ...
Speaking the truth on prostitution Jan 11, 2006
Taipei Times, ...do to me unless I was high," she said of her days as a sex worker, when she masked her pain through marijuana and methamphetamine hydrochloride, a stimulant ...
City police plans to clamp down on 'date rape' drugs Jan 10, 2006
Economic Times, The drugs — lorezapam, ketamine hydrochloride, alprazolam, gamma hydroxybutyric acid and flunitrazepam — are essentially sleeping pills or tranquilizers. ...
Cephalon, Inc. Announces Agreement with Mylan Pharmaceuticals Inc. ... Jan 10, 2006
PharmaLive.com (press release), The company currently markets four proprietary products in the United States: PROVIGIL, GABITRIL(R) (tiagabine hydrochloride), ACTIQ(R) (oral transmucosal ...
NitroMed Promotes Michael Sabolinski, MD to the Position of Chief ... Jan 6, 2006
Genetic Engineering News, ...and participate in certain key decision making processes relative to the development of BiDil(R) (isosorbide dinitrate/hydralazine hydrochloride) outside of ...
Memantine (Namenda) Found Effective for Advanced Alzheimer's ... Jan 10, 2006
SeniorJournal.com, ..."Although memantine hydrochloride helps treat the symptoms of Alzheimer’s disease, there is no evidence that it modifies the underlying pathology of the ...
CTMA OKs supplier switch Jan 12, 2006
Daily American Online (subscription), Chemstream, owned by Mike Kaufman of Boswell, will now provide the plant with sodium hydrochloride (chlorine) and phosphate, replacing SAL Chemical Co. ...
Customs officer recounts raid at hearing in ice case Jan 9, 2006
Pacific Daily News, ...afternoon as attorneys grilled Guam Customs and Quarantine officers about the raid of a hotel room allegedly being used to produce methamphetamine hydrochloride ...
Simply Fit Jan 12, 2006
Mercury-Register, ...after a meal. This formula contains betaine hydrochloride which starts the first phase of digestion in the stomach. It also provides ...
New hope for smokers Dec 23, 2005
USA Weekend ...up. And there are non-nicotine methods, including behavior modification and the prescription drug bupropion hydrochloride (Zyban). ...
GENZYME: Pipeline Highlights Jan 12, 2006
Webbolt Business News (subscription), Enrollment has been completed in a trial evaluating the product's equivalence to sevelamer hydrochloride for patients with end-stage renal disease. ...
2100 units but no ‘checks’ Jan 5, 2006
Hindustan Times, Ayurvedic officials received another complain that ephedrine hydrochloride was being mixed in ‘Som churn’ again the officials prefer to look the other way. ...
Date rape drugs available freely Jan 1, 2006
Times of India, There are at least three date rape drugs known internationally—GHB (gamma hydroxybutyric acid), Rohypnol (flunitrazepam) and Ketamine (ketamine hydrochloride ...
Andrx Files Patent Infringement Suit Against GlaxoSmithKline Over ... Dec 21, 2005
Patent Baristas, ...that GlaxoSmithKline's 150 milligram dose of extended-release Wellbutrin violates its patent covering a once-a-day form of bupropion hydrochloride, the active ...
Company Says FDA Has OK'd its Sodium Treatment Drug Dec 31, 2005
HealthCentral.com Astellas Pharma US Inc. said it would sell the drug, conivaptan hydrochloride, under the brand name Vaprisol, the Associated Press said. ...
Depomed Announces Positive Results of Phase II Clinical Trial for ... Jan 4, 2006
PharmaLive.com (press release), Proquin(R) XR (ciprofloxacin hydrochloride) once daily, extended-release tablets have been approved by the FDA for the treatment of uncomplicated urinary tract ...
NitroMed to Present at 24th Annual JPMorgan Healthcare Conference Jan 4, 2006
Genetic Engineering News, Massachusetts is a research-based emerging pharmaceutical company and the maker of BiDil(R) (isosorbide dinitrate/hydralazine hydrochloride), an orally ...
Trader gets life for selling shabu Jan 3, 2006
The Mindanao Daily Mirror, A 24-year-old compact disc vendor was sentenced to life imprisonment for selling eight small sachets of shabu (methamphe-tamine hydrochloride) at a pool resort ...
Amicus Therapeutics to Present at JPMorgan Healthcare Conference Jan 4, 2006
PR Newswire (press release), The company's lead compound Amigal(TM) (migalastat hydrochloride) is in Phase ll clinical trials for Fabry disease and the company plans to initiate clinical ...
Evidence questioned in ice case Jan 5, 2006
Pacific Daily News, Justin Keith Guerrero and Renea Dorleen Cruz-Taitano, who were arrested on charges of possession of methamphetamine hydrochloride as part of the September ice ...
Barrier Therapeutics Appoints Edward L. Erickson to Its Board of ... Jan 3, 2006
Market Wire (press release) US and Canada for the treatment of solar lentigines, a common condition also known as "age spots," and markets VANIQA®, (eflornithine hydrochloride) Cream 13.9 ...
Major new medication promising for black heart patients Jan 2, 2006
Fort Lauderdale Sun Sentinel, The two drugs -- hydralazine hydrochloride and isosorbide dinitrate -- increase nitric oxide that relaxes and dilates blood vessels to improve blood flow. ...
Advisory - Health Canada advises consumers not to use Kaizen ... Dec 28, 2005
Canada NewsWire (press release), Kaizen Ephedrine HCL tablets contain ephedrine hydrochloride, which is authorized by Health Canada only for use as a nasal decongestant in over-the- counter ...
Pharmacogenomic Test Predicts Chemo Toxicity 1/5/06 Jan 5, 2006
Bioscience Technology, ...test that identifies individuals at high risk of adverse reactions to the colon cancer chemotherapy drug irinotecan hydrochloride (Camptosar) is now being ...
Caraco Pharmaceutical Laboratories, Ltd. Announces FDA Final ... Dec 19, 2005
PR Newswire (press release), Drug Administration (FDA) have granted final approval for the Company's Abbreviated New Drug Application (ANDA) for Tramadol Hydrochloride with Acetaminophen ...
OxyContin(R) Dismissals and Withdrawals Exceed 400 Jan 5, 2006
Yahoo! News (press release) OxyContin Tablets are a controlled-release oral formulation of oxycodone hydrochloride indicated for the management of moderate to severe pain when a continuous ...
Amicus Therapeutics Appoints David J. Lockhart Chief Scientific ... Jan 6, 2006
Yahoo! News (press release) The company's lead compound Amigal(TM) (migalastat hydrochloride) is in Phase II clinical trials for Fabry disease and the company plans to initiate clinical ...
Health in 2005: the Efforts, the Results Jan 6, 2006
AllAfrica.com, During the conference, it was said a new drug, chlorproguannil hydrochloride-clapsone-artesunate, CDA, had been discovered to be an effective cure for ...
Two indicted for "ice" distribution Jan 4, 2006
KUAM.com, Wednesday. Pauline Marie Castro and John Junior Cruz were charged with distribution of methampethamine hydrochloride. According ...
Ukraine river contaminated with chlorine Dec 22, 2005
ITAR-TASS, ...mountainous Sivka River, a tributary of the Dniester River in the Ivano-Frankovsk region, has been contaminated with calcium hydrochloride, substance identical ...
Moldova says no warning from Ukraine over river contamination Dec 22, 2005
ITAR-TASS, Moldova about the contamination of Ukraine’s mountainous Sivka River, a tributary of the Dniester River, with calcium hydrochloride, substance identical to ...
Antibiotic approved for honeybee disease Jan 6, 2006
Capital Press (subscription), Before tylosin tartrate, only one other antibiotic, oxytetracycline hydrochloride (Terramycin), was available for use against American foulbrood. ...
Data Show Cost-Effectiveness of NitroMed's BiDil Through Reduced ... Dec 13, 2005
PharmaLive.com (press release), ...with Heart Failure" published today in Circulation: Journal of the American Heart Association, BiDil(R) (isosorbide dinitrate/hydralazine hydrochloride) is a ...
Aurobindo’s drug gets final nod from USFDA Dec 14, 2005
Daily News & Analysis, With this approval, coupled with the earlier tentative nod for its Sertraline Hydrochloride, dubbed as the bio-equivalent of Pfizer’s anti-depressant Zoloft ...
Targacept and AstraZeneca Announce Global License and Research ... Dec 31, 2005
Drug Newswire (press release), Targacept has a marketed product, Inversine(R) (mecamylamine hydrochloride), product candidates in clinical development for cognitive impairment, including ...
FDA Approves Astellas' Vaprisol® For Treatment Of Euvolemic ... Jan 1, 2006
Medical News Today (press release), ...that the US Food and Drug Administration (FDA) has approved VAPRISOL® (investigational name: YM087, generic name: conivaptan hydrochloride injection), an ...
NAACP and NitroMed Announce Partnership to Narrow Disparities in ... Dec 14, 2005
PharmaLive.com (press release), ...an aldosterone antagonist. BiDil is a fixed-dose combination of isosorbide dinitrate and hydralazine hydrochloride. While the exact ...
State to seize 'drug farm' Dec 22, 2005
News24, Nkosi said there was sufficient ephedrine hydrochloride, synthesized product and "tik" crystals on the farm premises to produce approximately 45 kg of "tik ...
Company says FDA OKs sodium level drug Dec 30, 2005
Seattle Post Intelligencer ...manufacturer said Friday. Astellas Pharma US Inc. said it would market the drug, conivaptan hydrochloride, as Vaprisol. It will be ...
DRL gets tentative US nod for antidepressan Dec 29, 2005
Sify, ...on Thursday received tentative approval from the US Food and Drug Administration for antidepressant drug sertraline hydrochloride. |Read more Finance news.|. ...
Sensex gains 41 pts @ 10:50 hrs Dec 29, 2005
Sify, ...cent to Rs 965.90 after it received on Thursday tentative approval from the US Food and Drug Administration for anti-depressant drug sertraline hydrochloride. ...
Indian shares climb, Colombo also up Dec 30, 2005
Daily Times, ...percent to Rs 978.50 after it received on Thursday tentative approval from the US Food and Drug Administration for anti-depressant drug sertraline hydrochloride ...
FDA OKs Caraco generic brand of Ultracet Dec 19, 2005
BusinessWeek ...less. The therapy combines a product called tramadol hydrochloride with acetaminophen, also known by its Tylenol brand name. Caraco ...
'Tik' farm seized Dec 22, 2005
News24, Nkosi said at the time there was enough ephedrine hydrochloride on the premises to produce approximately 45kg of "tik" with a value of R11.3m. ...
Dr Reddy's gets tentative nod for antidepressant Dec 30, 2005
Economic Times, ...on Thursday received tentative approval from the US Food and Drug Administration for antidepressant drug sertraline hydrochloride. ...
Metro/State business briefs Dec 20, 2005
DetNews.com, Monday that the US Food and Drug Administration has granted final approval for the company's new drug application for Tramadol Hydrochloride with Acetaminophen ...
FDA Issues Approvable Letter for VIVITROL(TM) (Formerly VIVITREX(R ... Dec 28, 2005
Business Wire (press release), The company currently markets four proprietary products in the United States: PROVIGIL(R) (modafinil) (C-IV), GABITRIL(R) (tiagabine hydrochloride), ACTIQ(R ...
Lilly Resolves Investigation of Its Evista Marketing and ... Dec 21, 2005
PR Newswire (press release), ...forward-looking statements. Evista(R) (raloxifene hydrochloride, Lilly) (Logo: http://www.newscom.com/cgi-bin/prnh/20031219/LLYLOGO ).
Targacept, AstraZeneca Enter TC-1734 Deal For Up To $300M Dec 28, 2005
BioWorld Online (subscription), Targacept has one marketed product, Inversine (mecamylamine hydrochloride), which was acquired from Sunnyvale, Calif.-based Layton Bioscience Inc. ...
Bio-IT Briefs Dec 22, 2005
Bio-IT World, ...its laboratory to determine through genetic screening which patients are likely to have a serious adverse reaction to irinotecan hydrochloride (Camptosar), a ...
State to Confiscate 'Tik' Farm Dec 22, 2005
AllAfrica.com, Mr Nkosi said there was sufficient ephedrine hydrochloride, synthesized product and "tik" crystals on the premises to produce approximately 45kg of "tik" with ...
Depomed, Biovail Revise Partnership Agreement for Development ... Dec 13, 2005
CCNMatthews (press release), ...agreement for the development and commercialization of Glumetza(tm), a once-daily, extended-release formulation of metformin hydrochloride (HCl) for the ...
BioCryst Initiates Intravenous Phase I/II Clinical Trial of ... Dec 22, 2005
PR Newswire (press release), ...(NASDAQ: BCRX) today announced that it has initiated a Phase I/II clinical trial of Fodosine(TM) (forodesine hydrochloride), the company's lead anti-cancer ...
America's Weight Problem - Where Is The Pharmaceutical Industry? Dec 19, 2005
Medical News Today (press release), Meridia® (sibutramine hydrochloride monohydrate) from Knoll Pharmaceuticals, one of two weight loss Rx drugs that have been approved by the Food and Drug ...
MGI PHARMA to Present at the JPMorgan Healthcare Conference Dec 21, 2005
Genetic Engineering News, MGI PHARMA markets Aloxi(R) (palonosetron hydrochloride) injection and Gliadel(R) Wafer (polifeprosan 20 with carmustine implant) in the United States. ...
Woman gets 46 months in ice case Dec 14, 2005
Pacific Daily News, Deanna Morales was sentenced in the US District Court of Guam yesterday after pleading guilty to possession of methamphetamine hydrochloride with intent to ...
Pyrotechnics Suspended in Guatemala Dec 30, 2005
Prensa Latina, The fact shocked Guatemalans and drove different sectors to request the prohibition of the petards made of hydrochloride of potassium and fulminating mercury. ...
Altair Nanotechnologies Expands Intellectual Property Portfolio ... Dec 19, 2005
Market Wire (press release) Altairnano products: -- Titanium dioxide pigment, as embodied in Altairnano's proprietary Hydrochloride Pigment process (AHP). -- Nano ...
Termination of firefighter reversed Dec 21, 2005
KUAM.com, ...reversed. John Troy Santos was charged with attempted possession with the intent to distribute methamphetamine hydrochloride. While ...
Cops bust shabu lab in Angeles City Dec 20, 2005
Sun.Star, ...scraped off from strainer funnels, drying pans, and other handling equipment by Babor's team tested positive of methamphetamine hydrochloride during an on-the ...
U Chicago researchers license pharmacogenomics test for patients ... Dec 21, 2005
EurekAlert (press release), ...have licensed a genetic test that determines which patients are likely to have a serious adverse reaction to irinotecan hydrochloride (Camptosar®), a key ...
A combined effort to end meth Dec 30, 2005
Daily Home Online, ...through state and federal grants, got retailers from Wal-Mart to Dollar General involved in tracking thefts of pseudoephedrine hydrochloride, ephedrine and ...
Cephalon, Inc. Completes Acquisition of Zeneus Holdings Limited Dec 22, 2005
Yahoo! News (press release) ...company currently markets four proprietary products in the United States: PROVIGIL® (modafinil) [C-IV], GABITRIL® (tiagabine hydrochloride), ACTIQ® (oral ...
Cephalon, Inc. Completes Acquisition of Zeneus Holdings Limited Dec 22, 2005
Boursorama, The company currently markets four proprietary products in the United States: PROVIGIL(R) (modafinil) [C-IV], GABITRIL(R) (tiagabine hydrochloride), ACTIQ(R ...
Altair Nanotechnologies and Western Oil Sands Extend Phase One of ... Dec 29, 2005
Market Wire (press release) Altairnano entered into a technology licensing agreement with Western Oil Sands Inc., in January 2004 to use the Altairnano Hydrochloride Pigment process (AHP ...
Chemicals send Disneyland workers to hospital Dec 16, 2005
OCRegister, ...the Anaheim Fire Department. The chemicals were hydrochloric acid and sodium hydrochloride, a bleach, she said. She said the result ...
Extended-Release Metformin Combo Drug Given the Green Light Dec 20, 2005
Diabetes Interview, Glumetza, a once-daily extended-release formulation of metformin hydrochloride, was granted FDA approval in June 2005 for the treatment of type 2 diabetes. ...
Abelson-Taylor Wins International Award Competitions Dec 19, 2005
PharmaLive.com (press release), ...an acne product used in the treatment of acne vulgaris, and a Sliver Award in the Dimensional Mailer Campaign for Allegra (fexofenadine hydrochloride), used to ...
Cat, cocaine and tik have firm hold on South Africans Dec 20, 2005
Mail & Guardian Online, ...in five provinces in the first six months of this year, almost one in three reported having used crack cocaine, cocaine hydrochloride, methamphetamine (tik ...
Hyperphosphatemia and Mortality: What's The Connection Dec 27, 2005
Medscape (subscription) ...of phosphorus from the gut include aluminum hydroxide, calcium carbonate, calcium acetate, magnesium carbonate, sevelamer hydrochloride, and lanthanum carbonate ...
Irritable Bowel Syndrome (IBS) Dec 16, 2005
WSOCtv.com, ...for IBS. Alosetron hydrochloride (Lotronex®) relaxes the colon and slows the passage of waste products through the bowel. The drug ...
Facing the hard facts... Dec 21, 2005
The Kerryman, It is generally sold on the street as cocaine hydrochloride - a fine, white crystalline powder, soluble in water, known in Kerry as ‘coke’, ‘C’ and ... | |
