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Methoxsalen
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DRUG INFO
Methoxsalen
Drug Name:
Methoxsalen
Indication: For the treatment of psoriasis and vitiligo
Pharmacology: Methoxsalen selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of Methoxsalen-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.
Mechanism Of Action: after activationm it binds preferentially to the guanine and cytosine moieties of DNA, leading to cross-linking of DNA, thus inhibiting DNA synthesis and function.
Drug Category: Antineoplastic Agents; Pigmenting Agents; ATC:D05AD02; ATC:D05BA02
Brand Names/Synonyms: Ammodin; Ammoidin; Meladinin; Meladinine; Meladoxen; Meloxine; Methoxa-Dome; Methoxalen; Methoxaten; Methoxsalen; New-Meladinin; Oxoralen; Oxsoralen; Oxsoralen Lotion; Oxsoralen-Ultra; Oxypsoralen; Proralone-Mop; Psoralen-Mop; Puvalen; Puvamet; Ultra Mop; Ultramop Lotion; Uvadex; Xanthotoxin; Xanthotoxine; Xanthoxin; Zanthotoxin
Dosage Forms: LIQUID
Absorption: Not Available
Interactions: Interactions for Methoxsalen:
Concomitant Therapy
Special care should be exercised in treating patients who are receiving concomitant therapy (either topically or systemically) with known photosensitizing agents such as anthralin, coal tar or coal tar derivatives, griseofulvin, phenothiazines, nalidixic acid, halogenated salicylanilides (bacteriostatic soaps), sulfonamides, tetracyclines, thiazides, and certain organic staining dyes such as methylene blue, toluidine blue, rose bengal and methyl orange.
Chemical IUPAC Name: Not Available
Chemical Formula: C12H8O4
Half Life: ~2 hours.
Drug Type: Approved Drug
# Accession No: APRD00157
CAS Registry Number: 298-81-7
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Methoxsalen News
(When available)
In a stunned locker room, 'next year' is a dim refrain 16 Jan 2006
Indianapolis Star, ...locker room. James unzipped a brown bag. He collected lotion, headphones and sundry personal items and packed them away. Feeling blue ...
Hands, Arm & Shoulder Massage Workshop Offered for Adults 16 Jan 2006
Kansas City infoZine, ...lot. Participants should wear a short-sleeved shirt. A partner is required and participants should bring hand lotion. Search for ...
What’s in the cosmetics you wear? 16 Jan 2006
Canton Repository (subscription), Eyes get rimmed in kohl liner, lips slicked in gloss. A dab of cologne on the neck, a dollop of body lotion on elbows and hands. ...
Twitching eye likely signals eyestrain, not diet problem 16 Jan 2006
Fort Wayne Journal Gazette, If your acne doesn’t respond, you may want to see your care provider for a stronger prescription lotion, such as tretinoin (Retin-A, Renova) or adapalene ...
GMT: Monday, Jan. 16 16 Jan 2006
WFAA (subscription), It makes no sense! Choose either lotion-based cleansers or gel cleansers that avoid the harsh ingredient, Sodium Laureth Sulfate. ...
A sparkling fairy tale 16 Jan 2006
This is London, Bentley). Beaten by his alcoholic father, Ste stays over at Jamie's and, via peppermint foot lotion, one thing leads to another. ...
Jacqueline's General Store - filled with unique 16 Jan 2006
Benton Evening News, ...“We also carry a wide selection of Boyd and Cottage collectibles, McCalls and aromatic candles, as well as body lotion,� Grear said. ...
Combat dry skin in winter 16 Jan 2006
Fort Wayne Journal Gazette, ...most spas can perform. Porrazzo recommends using a glycolic acid lotion to help remove the dead skin cells. “When you first start ...
At sea. Atlantic Rowing Race: Roz morale plumetting again 16 Jan 2006
BYM News (press release), ...as toilet paper). Then I anoint my nether regions with tea tree oil antiseptic lotion and/or Green People's Baby Salve. I've had ...
Today's To Dos 16 Jan 2006
Kinston Free Press, ...refresh, furniture polish, air freshners and oven cleaner, bath soap and body wash, toothpaste, toothbrushes, deodorant, hand and body lotion, alcohol, peroxide ...
Kerry Cue: Sand, surf and sun aside, a beach can't be beaten 16 Jan 2006
Advertiser Adelaide, One little gust of wind kicking up the sand and you convert your suntan-lotion-covered body into a wad of human-shaped sandpaper. ...
Marc Ecko Begins 1UP Video Blog 16 Jan 2006
1UP.com, ..."This is the first in a series of video blogs where I talk about Getting (It) Up, hand lotion, and even answer some of YOUR questions. ...
Green Enterprises Has a Breakthrough: Solar Heat & UV-Blocking ... Jan 15, 2006
PR Web (press release), Suntan lotion that provides protection from UV radiation is effective if – and this is a big IF – the lotion is re-applied thoroughly and regularly. ...
A cheap glow: Lotion to bronze the skin Jan 13, 2006
Waterloo Cedar Falls Courier, When Jergens Natural Glow Daily Moisturizer launched in the spring last year, a drugstore executive described it as the “hottest thing since Cabbage Patch ...
Lotion thief makes smooth getaway Jan 1, 2006
Fort Worth Star Telegram, A thief took dozens of bottles of body lotion and body sprays on Christmas Eve from a Dollar General store after posing as a customer. ...
Had a rough day? Smooth on lotion Jan 5, 2006
Jackson Clarion Ledger, To soften the blows of even the bleakest days, The Healing Garden has introduced Organics Wild Honey Body Lotion and Fig & Lavender Body Lotion (available at ...
Unique package takes lotion beyond the cosmetics aisle Dec 31, 2005
Everett Herald, The unique packaging is part of the marketing strategy for O'Keeffe's Working Hands, lotion for working people - including surgeons, US Postal Service workers ...
Lotion merchants squeezed by immigration officials Dec 21, 2005
Sioux City Journal, Seven Israeli citizens who until recently hawked lotion and other beauty products from two Southern Hills Mall kiosks are now facing the squeeze from US ...
Avoiding Sweet Lotion Scents May Make Sense Dec 22, 2005
NBC 10.com, DALLAS -- It's hard enough to resist the sweet treats that surround the holidays, but now, some say you should also avoid the scents. ...
Fashion poll: Skinny jeans? Jan 13, 2006
Minneapolis Star Tribune (subscription), CHEAP INDULGENCE Healing Garden Relaxtherapy 2-in-1 Moisturizing Body Wash With Lotion, $6.39 at www.drugstore.com If you need a winter pick-me-up, try this ...
Dealing with post-New Year breakouts Jan 12, 2006
Asianjournal.com, VMV Superskin 3 Acne controlling exfoliating astringent; Belo CHAT 2% (Clindamycin, Hydroquinone, Alum and Tretinoin); or Mario Badescu Special Cleansing lotion ...
Mystic Orient Increases Product Line with Silk & Satin Body Lotion Jan 3, 2006
PR Web (press release), Mystic Orient -- makers of exquisite handmade soaps, lotions, and spa products -- is pleased to announce its silkiest lotion ever! ...
No better way on offer to keep in touch with sunny running game Jan 14, 2006
Scotsman, Fourteen degrees! Scots break out the sun tan lotion at those temperatures because we are lucky to see them from November to March inclusive. ...
Remember When Jan 12, 2006
Harbor Light, ...s Drug Store featured one of their rhymes: Face the world with lovely skin; The kind of which you dream, by using Tussy’s Wind & Weather, in lotion or in ...
Here's what you need to start a business Jan 15, 2006
Tallahassee.com, ...does. A few years ago, I was consulting with a suntan-lotion company in Miami, and the company's name was all over its cars. Wherever ...
Sherri Byrand column: Bright spots in a fog that never lifts Jan 15, 2006
Sheboygan Press, She allowed me to massage her sore feet, try to work out the muscle spasms in her back, and rub lotion on the dry skin on her arms, as she had been scratching ...
Wash your face, scrub your heels Jan 15, 2006
Belleville News-Democrat, Stop ignoring those cracked heels. Scrub them very gently in the shower with a pumice stone and apply lotion twice daily. Do not eat your cuticles. ...
Manly? ... yes Jan 1, 2006
Mail Tribune, The unique packaging is part of the marketing strategy for O’Keeffe’s Working Hands: lotion for working people — including surgeons, US Postal Service ...
Moisturizers help calm winter's dry skin needs Jan 2, 2006
Shreveport Times, Following are their observations. All Day Moisture Body Lotion, by The Healing Garden, $6.75. ... Milk and Honey Body Lotion by Burt's Bee, $8.99. ...
Poll respondents share their opinions on moisturizer tailored for ... Jan 6, 2006
Salem Statesman Journal, So now the StatesmanJournal is using it's readership as a focus group for lotion packaging!? ... "Corn Huskers" lotion is good stuff. ...
French women do get fat Jan 13, 2006
Scotsman, ...on the beach. From a young age females learn to rub sand and sun lotion into their thighs to prevent cellulite. In an international ...
Why sake isn't always bad for your skin Jan 13, 2006
The Daily Yomiuri, ...dermatitis. Yushin-Brewer has started selling lotion containing the extract, and is now working on anti-ulcer products. Because ...
Aging men lead boom in skin care products Jan 12, 2006
Asahi Shimbun, ...expansion.". About a year ago, a 51-year-old Tokyo office worker started using a lotion after his only daughter graduated from university. ...
Post-Salad-Days Women Agree: They Want 'What She's Having' Jan 12, 2006
New York Times, ...book up with her own experiences. ("I rub moisturizing lotion gently into Robert's skin," she writes. "I love seeing him standing ...
Fairly painless resolutions to improve your looks Jan 11, 2006
Seattle Times, Stop ignoring those cracked heels. Scrub them very gently in the shower with a pumice stone and apply lotion twice daily. Do not eat your cuticles. ...
Beautiful eyes Jan 3, 2006
Sun2Surf, The complete whitening care offers Sensational White Serum EX, Cleansing Oil, Washing Cream, Lotion, Moisturiser L & Moisturiser R, Toning Lotion, Protective ...
Wal-Mart weaves in wellness Jan 14, 2006
Fort Wayne Journal Gazette, ...products company that makes products as varied as Mrs. Dash salt-free seasonings, Wish-Bone salad dressings, Lipton tea and Vaseline Intensive Care lotion. ...
The New Ponds Googly Woogly Queens 2006 Jan 13, 2006
Xtvworld (press release), The Skincare range comprises of Moisturizing Cold Cream, launched in India in the year 1947, and the all-new Ponds body Lotion with Triple Vitamins. ...
Hilton Hotels fires up 'Re-ignition' campaign with $1 billion ... Jan 12, 2006
e-Travel Blackboard (press release), ...guests will be treated to Hilton's exclusive Crabtree & Evelyn's La Source(R) bath amenities -- which include shampoo, conditioner, lotion and mouthwash. ...
Volunteer Here Jan 14, 2006
Flint Journal, Sit with a patient, hold a hand and listen to stories from the past, watch old movies together, lotion their hands, polish their nails, assist with a meal or ...
Young Island Resort Jan 10, 2006
Luxist, Mother Botanicals of Barbados such as a Bajan cane sugar body scrub, Sea Salt body scrub, Ylang Ylang hydrating cream, Vanilla bean body lotion, guava seed ...
Some autistic kids' parents dispute criticism of nontraditional ... Jan 13, 2006
TMCnet Chelation usually involves taking a chemical _ by pill, injection or lotion _ that binds with heavy metals in the body and comes out in the urine. ...
Most Organic For Your Money Jan 12, 2006
KLAS-TV, ...while spending wisely. You're also seeing more organic labels on cosmetic items, such as shampoo and body lotion. Consumer Reports ...
Help for your style resolutions Jan 9, 2006
Kansas.com, Stop ignoring those cracked heels. Scrub them gently in the shower with a pumice stone and apply lotion twice daily. • Do not eat your cuticles. ...
Pennsylvania American Water Suggests Frequent Hand Washing to ... Jan 12, 2006
PR Newswire (press release), Pat skin dry, don't rub, to avoid chapping or cracking. -- Apply hand lotion after washing to help prevent or soothe dry skin. Individuals ...
VVF set to launch new products Jan 12, 2006
Sify, Jindal said the company is also entering the body wash and body lotion segments and these would also make its presence in the retail space immediately after ...
Travel Journal Jan 12, 2006
Syracuse Post Standard, What did you pack that came in handy? You need you bathing suit, camera, suntan lotion, and credit card. Things can get expensive on Capri. Did you feel safe? ...
Resolve to Play Your Best! Jan 12, 2006
Golf For Women Magazine Golfers, he says, should apply a nongreasy formula with an SPF 15 or higher 20 minutes before a round to give the lotion time to sink in. ...
Two's Company debuting Amanda Depew line Jan 12, 2006
Home Accents Today, ...stores. The collection includes soap sets, air mists, soap and lotion sets, candles, hand towels, jewelry cases and hatboxes. Retail ...
WHAT'S THE ALTERNATIVE? Jan 13, 2006
Glasgow Daily Record, Here's some everyday products you can use in their place. Wash your hair, and then use a squirt of moisturising lotion before rinsing. ...
Wave of the future Jan 13, 2006
Culpeper Star Exponent, Whether a person has ink, glue, lotion, mucus, nicotine residue or any other goop or smudge on his or her finger, the ultrasound technology reads right through ...
Centuria: 100 Ouroboric Novels Jan 12, 2006
California Literary Review, Consider the opening of “novel� Sixty-Two: “Exiting a shop into which he had entered to purchase an aftershave lotion, a middle-aged gentleman, well ...
New Options for Adult Acne Jan 13, 2006
Fashion Monitor Toronto, If your acne doesn’t respond, you may want to see your care provider for a stronger prescription acne lotion such a tretinoin (Retin-A, Renova) or adapaline ...
Quick fixes to make you look perfectly groomed and gorgeous in no ... Jan 13, 2006
Glasgow Daily Record, To kill off a spot, apply a dab of calamine lotion or Milk Of Magnesia to the blemish at bedtime and it will be gone by morning. ...
Turning a cultural wasteland into a hub Jan 14, 2006
Miami Herald, ...``There was no museum. There were no resident artists. What there was was suntan lotion and water skiing. ``I started to cry. I learned to water ski. ...
Cream May Help Eliminate Cellulite Jan 13, 2006
Local6.com, ...cream several years ago. However, they could not find a lotion that would allow the drug to penetrate the skin. Many studies on ...
Silky smooth skin Dec 17, 2005
Sun2Surf, Nivea Whitening Body Lotion is a light but hydrating lotion with vitamin E that is said to absorb quickly and won’t leave you feeling sticky and greasy. ...
Hammer, Nails, Moisturizer ... Jan 5, 2006
The Register-Guard, The unique packaging is part of the marketing strategy for O'Keeffe's Working Hands: lotion for working people - including surgeons, US Postal Service workers ...
Keeping skin healthy during colder months Jan 13, 2006
MSNBC St. Luke's Hospital in New York City, says consumers shouldn't feel inclined to purchase a lotion or cream just because of price. ...
Doctor admits to defrauding people with miracle head lice ... Jan 3, 2006
Newstarget.com, Dr. Dale Pearlman, who began selling an expensive head lice treatment lotion last year, has admitted that the concoction is actually a skin cleanser widely ...
It's a dry winter, so exfoliate and moisturize your skin Dec 23, 2005
Arizona Republic, Following are their observations. All Day Moisture Body Lotion by the Healing Garden, $6.75. ... Milk & Honey Body Lotion by Burt's Bees, $8.99. ...
UPDATE 2-Alberto-Culver to sell Sally Beauty unit to Regis Jan 10, 2006
Reuters ...and St. Ives lotion, while Regis would combine the Sally Beauty business with its Supercuts, Vidal Sassoon and other salons. The ...
Business Roundup Jan 11, 2006
Monsters and Critics.com, Ives lotion and its VO5, Tresemme and Nexxus hair products to retailers and discounters, the Chicago Sun-Times reported Wednesday. ...
Alberto-Culver to sell its distribution business Jan 11, 2006
Chicago Sun-Times, Ives lotion and its VO5, Tresemme and Nexxus hair products to drugstores, grocery stores and discounters such as Target, Kmart and Wal-Mart. ...
On TV, provocative doesn't sell Jan 12, 2006
International Herald Tribune, In addition to Combe, they included the Burlington Coat Factory Warehouse; Chattem, for Gold Bond lotion; Icy Hot pain reliever; and movie studios like ...
Cap those winter hair problems Jan 7, 2006
Indianapolis Star, ...hair. If you want a straight look, use a straightening cream as you blow-dry; if you want a gentle curl, use a curl lotion. Either ...
Help Skin Survive a Cruel Season Jan 4, 2006
New York Times, The temperature there last week was minus 29 degrees. If it gets any colder, Mr. Richer also insulates his skin with lotion. "What ...
Makeover 911 : Start the year by saving Jan 5, 2006
INQ7.net, Makeup removers are often called names with the word "cleansing" before them like cold cream, lotion and my personal favorite, cleansing oil. ...
High-Dose Steroids Up Heart Disease Risk Greatly Jan 10, 2006
PakTribune.com, Many people have to take steroid drugs -- for example, by inhaler to treat asthma or in lotion form for skin allergies, while others need to take the drugs by ...
Soothe that dry winter skin Dec 25, 2005
Louisville Courier-Journal, Their observations: All Day Moisture Body Lotion, by The Healing Garden, $6.75. Special ... afterward.". Skin Nourishing Lotion by Lubriderm, $2.99. ...
US: ALBERTO-CULVER SELLS SALLY BEAUTY TO REGIS Jan 11, 2006
Namnews, ...and St. Ives lotion, while Regis would combine the Sally Beauty business with its Supercuts, Vidal Sassoon and other salons. Regis ...
EZ-EM Reports Second Quarter Fiscal 2006 Financial Results ... Jan 10, 2006
Genetic Engineering News, ...was attributable to: growth of CT and fluoroscopy products; the Empower(R) family of injectors systems; Reactive Skin Decontamination Lotion (RSDL); and ...
Cedar Fire Victim Protests Ban On Medical Pot Jan 9, 2006
NBC Sandiego.com, The San Diego County Sheriff's Department raided Reyes' home and confiscated products including pills and lotion, NBC 7/39 reported. ...
Cedar Fire Victim Has New Battle With Marijuana Jan 9, 2006
10News.com, ...marijuana is illegal under federal law. Thanks to a friend, Reyes has a little cream, oil and lotion left. Reyes says this will last ...
Addition of Dallas' Landmark Anatole Hotel Kicks off the Year of ... Jan 10, 2006
Business Wire (press release), Hilton Serenity Bath(TM) - A Hilton exclusive, Crabtree & Evelyn's La Source bath amenities include shampoo, conditioner, lotion and mouthwash. ...
Fort Pierce man arrested on charge of sexual battery on ... Jan 10, 2006
Fort Pierce Tribune (subscription), ...any wrongdoing; but when he allowed detectives to search his house, they found a pornographic DVD, a bathing suit, a sex toy and massage lotion — all of ...
What should we do with Tafa Balogun’s apology? Jan 9, 2006
Daily Sun, ...sins forgiven. Unlike the reaction that trailed his six-month prison sentence, Balogun’s apology came as a soothing lotion. And ...
Insider's blog on Detroit auto show Jan 11, 2006
Autoblog, ...the show, including the blizzard that engulfed journalists at the Chrysler Aspen debut and Toyota’s announcement that the Camry’s seats contain skin lotion ...
Popping the cap on closures Jan 8, 2006
Ferret, ...accelerate. “Trigger sprayers continue to grow, lotion dispensers continue to grow, and the use of sports closures continues to grow.�. ...
Second Thoughts Jan 9, 2006
Arkansas Democrat-Gazette (subscription), ...get the ring off. “I had lotion all over my hands, spit, you name it, anything to get it off,� Smith said. “I just kept pulling ...
Getting to know Ryan Valleskey Jan 10, 2006
Sheboygan Press, You were banished to a desert island for a month? Which three possessions would you bring with you? Radio, suntan lotion, hammock. What's your No. 1 pet peeve? ...
Wrap Your Skin in New Olay Ribbons Body Wash! Jan 11, 2006
PR Newswire (press release), The formulas include: * Olay Body Wash plus Lotion Ribbons with Aloe Extract contains 20 percent moisturizers * Olay Body Wash plus Crhme Ribbons with Almond ...
Canada's Jamieson Laboratories puts revolutionary skincare line on ... Jan 3, 2006
Canada NewsWire (press release), For example, the Rx Lift & Renew System is a three step kit which contains an instant 'lift' serum, a lotion that maintains and protects, and supplements that ...
Inqlings | What Chris Brown wants he gets, batteries included Jan 10, 2006
philly.com, Now for his nonfood needs: unspecified "lotion," Listerine mouthwash, Colgate toothpaste, toothbrush, ChapStick, 10 white hand towels, 10 white full-size towels ...
Run to the Sun! Orbitz' Super Sand & Sea Sale is Caribbean Hot! Jan 9, 2006
PR Newswire (press release), 9 /PRNewswire/ -- Throw out that bulky sweater, run to the drug store for some SPF 30 sun tan lotion and break out your swim suit, because Orbitz (http://www ...
Saving the Fish to Save the Reefs Jan 9, 2006
New York Times, ...(As a control, other lizards had plain moisturizing lotion applied.) The researchers found that when males had their UV reflectance reduced, they were more ...
Woman harassed by telemarketer Jan 4, 2006
Bridgeton News, A 35-year-old South West Avenue woman called police on Monday to say that an unknown facial lotion company has been calling her several times to advertise ...
Cathy Weaver: Community helps The Cancer Center Jan 9, 2006
Greensboro News Record, Four months later, the Cancer Care Cart has travel-size toothpaste, toothbrushes, baby powder, lotion, combs and brushes, crossword puzzles, packets of tissues ...
Sometimes it's hard just to find good lip service Jan 9, 2006
The Gloucester County Times, I have extremely dry and sensitive skin. I am a connoisseur of any cream-balm-salve-lotion and this Lip Infusion stuff doesn't cut the mustard. ...
Man sues over online prescription Jan 10, 2006
Chicago Sun-Times, Schmidt suffered brain damage after taking Xanax and Ultram, anti-anxiety drugs that depress the central nervous system, said his attorney, Edmund J. Scanlan. ...
UPDATE 1-Biovail seeks strict tests for Wellbutrin clones Dec 21, 2005
Reuters ..."Biovail has much to lose, with over 40 percent of sales currently coming from the franchise and needs to maintain a bridge until it can launch Ultram ER.". ...
DESPERATE HOUSEWIVES� NOT DESPERATE ENOUGH Jan 3, 2006
I-Newswire.com (press release) REAL DESPERATE HOUSEWIVES have our own stash of Xanax, Prozac, Valium, Ativan, Buprenex, Oxycontin, Soma, Hydroxyzine, Ultram, Vicodin, Darvon, Tylenol with ...
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