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Methoxamine
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DRUG INFO
Methoxamine
Drug Name:
Methoxamine
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Indication: Indicated for the treatment and management of hypotension.
Pharmacology: Methoxamine is a potent sympathomimetic amine that increases both systolic and diastolic blood pressure. Methoxamine is indicated for prevention and treatment of the acute hypotensive state occurring with spinal anesthesia. It is also indicated as adjunctive treatment of hypotension due to hemorrhage, reactions to medications, surgical complications, and shock associated with brain damage due to trauma or tumor. Methoxamine acts on both α1-adrenergic receptors but appears to have no effect on β-adrenergic receptors. It acts by increasing the force of the heart's pumping action as well as constricting peripheral blood vessels.
Mechanism Of Action: Methoxamine acts through peripheral vasoconstriction by acting as a pure alpha-1 adrenergic receptor agonist, consequently increasing systemic blood pressure (both systolic & diastolic).
Drug Category: Vasoconstrictor Agents; Sympathomimetic; ATC:C01CA10
Brand Names/Synonyms: Methoxamedrine; Methoxamin; Methoxamine; Methoxaminum [Inn-Latin]; Metossamina [Dcit]; Metoxamina [Inn-Spanish]; Pseudomethoxamine; Vasoxine; Vasoxyl
Dosage Forms: LIQUID
Absorption: Not Available
Interactions: Not Available
Chemical IUPAC Name: 2-amino-1-(2,5-dimethoxyphenyl)-propan-1-ol
Chemical Formula: C11H17NO3
Half Life: Not Available
Drug Type: Approved Drug
# Accession No: APRD00062
CAS Registry Number: 390-28-3
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