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Lutropin alfa
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DRUG INFO
Lutropin alfa
Drug Name:
Lutropin alfa
Indication: For treatment of female infertility
Pharmacology: Used to facilitate female conception, lutropin alfa performs the same actions as luteinizing hormone (LH), which is normally produced in the pituitary gland. Lutropin is usually given in combination with follitropin alfa. In females, a LH surge about halfway through the menstrual cycle triggers the onset of ovulation. LH also induces the ovulated follicle to become a corpus luteum, which then secretes progesterone.
Mechanism Of Action: Binds to the luteinizing hormone receptor which then activates adenylate cylcase through G protein mediation. Adenylate cyclase then activates many other pathways leading to steroid hormone production and other follicle maturation processes.
Drug Category: Fertility Agents
Brand Names/Synonyms: Lutropin beta chain precursor;Luteinizing hormone beta subunit;LSH- beta;LSH-B;LH-B; Luveris (Serono)
Dosage Forms: Not Available
Absorption: Not Available
Interactions: Not Available
Chemical IUPAC Name: Human luteinizing hormone
Chemical Formula: C1014H1609N287O294S27 >BetaChain (LH)
Half Life: 4.4 hours (mammalian reticulocytes, in vitro)
Drug Type: Approved Drug
# Accession No: BIOD00056
CAS Registry Number: 152923-57-4
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Lutropin alfa News
(When available)
Dead kangaroos don’t bounce, do they? Jan 14, 2006
Business Online, ...development. The company markets eight recombinant products – Rebif, Gonal-f, Saizen, Serostim, Ovidrel, Luveris, Zorbtive and Raptiva. ...
Serono Announces Formal Conclusion of Serostim Settlement Dec 15, 2005
PharmaLive.com (press release), ...are Rebif(R) (interferon beta-1a), Novantrone(R) (mitoxantrone for injection concentrate), Gonal-f(R) (follitropin alfa for injection), Luveris(R) (lutropin ...
Serono Announces Formal Conclusion of Serostim Settlement Dec 15, 2005
Yahoo! News (press release) ...are Rebif® (interferon beta-1a), Novantrone® (mitoxantrone for injection concentrate), Gonal-f® (follitropin alfa for injection), Luveris® (lutropin alfa ...
Serono Completes Second Phase III Trial of its Proprietary ... Jan 8, 2006
Yahoo! News (press release) The Company has eight biotechnology products, Rebif®, Gonal-f®, Luveris®, Ovidrel® /Ovitrelle®, Serostim®, Saizen®, Zorbtive(TM) and Raptiva®. ...
Serono Completes Second Phase III Trial of its Proprietary ... Jan 8, 2006
PR Newswire (press release), The Company has eight biotechnology products, Rebif(R), Gonal-f(R), Luveris(R), Ovidrel(R) /Ovitrelle(R), Serostim(R), Saizen(R), Zorbtive(TM) and Raptiva(R ...
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