Indication: For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms
Pharmacology: Lorazepam, a benzodiazepine not transformed to active metabolites, is used to treat anxiety, status epilepticus, and for sedation induction and anterograde amnesia.
Mechanism Of Action: Lorazepam binds to central benzodiazepine receptors which interact allosterically with GABA receptors. This potentiates the effects of the inhibitory neurotransmitter GABA, increasing the inhibition of the ascending reticular activating system and blocking the cortical and limbic arousal that occurs following stimulation of the reticular pathways.
Drug Category: Anti-anxiety Agents; Hypnotics and Sedatives; Antiemetics; Anticonvulsants; Benzodiazepines; ATC:N05BA06
Absorption: readily absorbed with an absolute bioavailability of 90 %.
Interactions:
DrugBank: Interactions for Lorazepam
Interactions for Lorazepam:
Tablets: The benzodiazepines, including lorazepam, produce CNS-depressant effects when administered
with such medications as barbiturates or alcohol.
Injection: Lorazepam injection, like other injectable benzodiazepines, produces depression of the
central nervous system when administered with ethyl alcohol, phenothiazines, barbiturates, MAO inhibitors, and other
antidepressants.When scopolamine is used concomitantly with injectable lorazepam, an increased incidence of sedation,
hallucinations, and irrational behavior has been observed.
Chemical IUPAC Name: 9-chloro-6-(2-chlorophenyl)-4-hydroxy-2,5-diazabicyclo[5.4.0]undeca-5,8,10,12-tetraen-3-one
Chemical Formula: C15H10Cl2N2O2
Half Life: 12 hours
Drug Type: Approved Drug
# Accession No: APRD00116
CAS Registry Number: 846-49-1
Lorazepam News (When available)
Q&A: Pete WentzJan 12, 2006 Rolling Stone In 2005, you OD'd on Ativan and nearly died while sitting in a car in a Best Buy parking lot. Were you listening to music? Not a good experience at all. ...
Fired BYU professor loses suitDec 24, 2005 Provo Daily Herald, ..."Their concern was ... that he had given a student Ativan. What they said was they couldn't get over that issue.". Ativan is the ...
Deputies: Doctor ignored suspensionJan 9, 2006 St. Petersburg Times, Lorazepam is a generic form of the drug Ativan, which, according to the Food and Drug Administration, is used to treat several conditions, including anxiety. ...
Christiansburg teen battles tumor problemsDec 30, 2005 Roanoke Times, His folks took him to a Fairfax hospital for treatments. He had two seizures and was transported back to UVa after getting a dose of Ativan for stabilization. ...
Two Women Accused Of Exploiting UncleDec 16, 2005 Sequoyah County Times, 16, 2004, and found to be positive for a drug called Ativan, which is a type of drug used to relieve anxiety, nervousness, and tension associated with anxiety ...
DESPERATE HOUSEWIVES� NOT DESPERATE ENOUGHJan 3, 2006 I-Newswire.com (press release) REAL DESPERATE HOUSEWIVES have our own stash of Xanax, Prozac, Valium, Ativan, Buprenex, Oxycontin, Soma, Hydroxyzine, Ultram, Vicodin, Darvon, Tylenol with ...
A New Year’s ResolutionJan 4, 2006 PR Web (press release), Drugs such as Klonopin, Xanax, Ativan and Valium are generally prescribed for anxiety or insomnia but also have a side effect of anxiety or panic that may ...
ASPARTAME, NOT CONVICT, KILLED HUBBY?Jan 2, 2006 Free Market News Network, ...hospital. During treatment, Fleming was given Ativan because he was combative and confused; from there, he slipped into a coma and died. ...
Health professionals disciplinedJan 1, 2006 Springfield State Journal Register, Her registered nurse license was placed on probation for three years for taking Ativan for personal use while she was employed at Abraham Lincoln Memorial ...
Left behind by suicide, families seek answers, preventionJan 7, 2006 Hamilton Journal News (subscription), Banks believes doctors failed her daughter, prescribing nearly two dozen medications like Oxycontin, Paxil, and Ativan that confused her mind and led to her ...
Expert says BYU professor's firing cost $1MDec 15, 2005 New Utah, ...was dismissed from the school in 2001 after accusations he violated the law and university policy by giving the anti-anxiety controlled substance Ativan to a ...
Professor's lawyer: BYU violated own firing policyDec 20, 2005 New Utah, ...the guise of prescribing it for his cat, using university supplies of veterinary Claritin himself and providing a student with the controlled substance Ativan. ...
BYU personnel official testifies against ThwaitsDec 16, 2005 Provo Daily Herald, He later gave Ativan to another student. "He has a responsibility to prevent an illegal act and something potentially harmful to a student," Flake said. ...
Paramedic arrested on drug-related chargesDec 12, 2005 Winston-Salem Journal, ...vials. They say that he also took small amounts of the painkiller Demerol and Ativan, a drug used to relieve symptoms of anxiety. ...
Editorial 01/16: Sierra Club's newest hero?16 Jan 2006 commercialappeal.com (subscription), Now, we're not quite ready to put Hyneman into the same category as the Lorax, the Dr. Seuss character who waged a lonely battle against the wanton pillaging ...
Green powerDec 15, 2005 Colorado Springs Independent, Carson busy acquiring open space, installing solar panels and water-thrifty irrigation sensors, and promoting Dr. Seuss' environmental fable The Lorax in area ...
Best Bets: A daily list of Central Texas' best eventsJan 2, 2006 Austin American-Statesman (subscription), ...and illustrations from Lea's novel "The Brave Bulls" and World War II political cartoons and original illustrations from Seuss' children's book "The Lorax.". ...
Last Minute Holiday ShoppingDec 21, 2005 The Green Guide, ...& Co., 2000, $7.95). And for the kid in us all check out The Lorax by Dr. Seuss (Random House, 1971, $10.17). For more book suggestions ...
Outstanding volunteerDec 18, 2005 Orlando Sentinel, A Taste of Honey. The cast and crew of The Lorax received a superior rating in the One Act category. Participants who received a ...
Playful poets, rollicking rhymestersDec 17, 2005 Malaysia Star, Sound-play and strong rhythms engage children right away, and off they go into the strange worlds of The Cat in the Hat, The Lorax, and Green Eggs and Ham to ...
Week 15 rundown: No miracle this timeDec 14, 2005 FOXSports.com ...planted elsewhere on the property. This is what happens when the Lorax runs unopposed for alderman. Football Outsiders.com tackles ...
More yuks than yawnsDec 13, 2005 Miami Herald, Bhuiyan, 16. ''He does fun stuff to keep you awake,'' the Davie junior said. ``He read us, like, The Lorax by Dr. Seuss.''. Much like ...
Public display of confectionDec 23, 2005 Jerusalem Post, One might think it was Peled's fascination with all things marzipan that led her to create the Kvar Tavor Marzipan Museum, near Mount Tabor in the Galilee. ...
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