Indication: For use in management of asthma, wheezing, and chronic asthmatic bronchitis.
Pharmacology: Isoetharine is a relatively selective beta2-adrenergic bronchodilator. Isoetharine is indicated for the relief of bronchospasm associated with chronic obstructive pulmonary disease. Adrenergic bronchodilators are breathed in through the mouth to open up the bronchial tubes (air passages) of the lungs.
Mechanism Of Action: The pharmacologic effects of isoetharine are attributable to stimulation through beta-adrenergic receptors of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic AMP. Increased cyclic AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.
Drug Category: Bronchodilator Agents; Adrenergic beta-Agonists
Interactions:
DrugBank: Interactions for Isoetharine
Interactions for Isoetharine:
May interact with the following: beta-adrenergic blocking agents (these
medicines may make your condition worse and prevent the adrenergic bronchodilators from working properly) and
disopyramide, quinidine, phenothiazines, and procainamide (these medicines may increase the risk of heart problems).
Chemical IUPAC Name: 4-[1-hydroxy-2-(1-methylethylamino)butyl]benzene-1,2-diol
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