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Hyaluronidase
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DRUG INFO
Hyaluronidase
Drug Name:
Hyaluronidase
Indication: Enhances absorption and distribution of drugs and anesthetics, Also used for rehydration
Pharmacology: Hyaluronidase hydrolyzes hyaluronic acid by splitting the glucosaminidic bond between C1 of the glucosamine moiety and C4 of glucuronic acid. This temporarily decreases the viscosity of the cellular cement and promotes diffusion of injected fluids or of localized transudates or exudates, thus facilitating their absorption.
Mechanism Of Action: Hydrolyzes hyaluronic acid by splitting the glucosaminidic bond between C1 of the glucosamine moiety and C4 of glucuronic acid.
Drug Category: Permeabilizing Agents; Anesthetic Adjuvants; enzymes (44:00.00)
Brand Names/Synonyms: Hyaluronidase 1 precursor;Hyal-1;Hyaluronidase PH-20;Sperm surface protein PH-20;Sperm adhesion molecule 1; Vitrase (Ista Pharma)
Dosage Forms: LIQUID
Absorption: Not Available
Interactions: Not Available
Chemical IUPAC Name: Sheep hyaluronidase
Chemical Formula: C2455H3775N617O704S21
Half Life: Not Available
Drug Type: Approved Drug
# Accession No: BIOD00022
CAS Registry Number: 488712-31-8
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Hyaluronidase News
(When available)
ISTA Pharmaceuticals Announces Acceptance of ISTA's European ... Jan 12, 2006
PR Newswire (press release), Vitragan is ISTA's proprietary formulation of highly purified ovine hyaluronidase which is commonly known in the US as Vitrase(R). A vitreous hemorrhage occurs ...
ISTA's eye treatment under EU review Jan 12, 2006
Pharmaceutical Business Review 12 Jan 2006, 17:44 GMT - Vitragan is ISTA's proprietary formulation of highly purified ovine hyaluronidase, which is commonly known in the US as vitrase. ...
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