Indication: For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful.
Pharmacology: Hexachlorophene, a detergent cleanser, is an antibacterial sudsing emulsion for topical administration. It is a bacteriostatic cleansing agent. It cleanses the skin thoroughly and has bacteriostatic action against staphylococci and other gram-positive bacteria. Cumulative antibacterial action develops with repeated use. Cleansing with alcohol or soaps containing alcohol removes the antibacterial residue.
Mechanism Of Action: The primary mechanism of action of hexachlorophene, based on studies with Bacillus megatherium, is to inhibit the membrane-bound part of the electron transport chain, respiratory D-lactate dehydrogenase. It induces leakage, causes protoplast lysis, and inhibits respiration.
Absorption: Detectable blood levels of hexachlorophene following absorption through intact skin have been found in subjects who regularly scrubbed with hexachlorophene.
Interactions:
DrugBank: Interactions for Hexachlorophene
Interactions for Hexachlorophene:
No information available.
Chemical IUPAC Name: 3,4,6-trichloro-2-[(2,3,5-trichloro-6-hydroxy-phenyl)methyl]phenol
Chemical Formula: C13H6Cl6O2
Half Life: Not Available
Drug Type: Approved Drug
# Accession No: APRD00722
CAS Registry Number: 70-30-4
Hexachlorophene News (When available)
low level chemical sprays to begin shortly in the westDec 30, 2005 Bay Area Indymedia, ...includes 4 new chemicals and 14 other pesticides, including 2,4-D, bromacil, chlorsulfuron, diquat, diuron, fluridone, hexazinone, teburthiruon, triclopyr, and ...
Home
Copyright phasechange.org 2006.
All Rights Reserved.
