Halofantrine resources


DRUG INFO
Halofantrine

Drug Name: Halofantrine

Indication: For treatment of Severe malaria



Pharmacology: Halofantrine is a synthetic antimalarial which acts as a blood schizonticide. It is effective against multi drug resistant (including mefloquine resistant) P. falciparum malaria.

Mechanism Of Action: The mechanism of action of Halofantrine may be similar to that of chloroquine, quinine, and mefloquine; by forming toxic complexes with ferritoporphyrin IX that damage the membrane of the parasite.

Drug Category: Antimalarials; ATC:P01BX01

Brand Names/Synonyms: Halfan; Halofantrina; Halofantrina [Inn-Spanish]; Halofantrine; Halofantrine [Usan]; Halofantrinum; Halofantrinum [Inn-Latin]

Dosage Forms: TABLET

Absorption: Not Available

Interactions: Not Available



Chemical IUPAC Name: 3-dibutylamino-1-[1,3-dichloro-6-(trifluoromethyl)phenanthren-9-yl]-propan-1-ol

Chemical Formula: C26H30Cl2F3NO

Half Life: 6-10 days

Drug Type: Approved Drug

# Accession No: APRD00419

CAS Registry Number: 69756-53-2



Halofantrine News
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Through The Looking-Glass  Jan 6, 2006
Barnstable Patriot, When I was your age, I always did it halfan- hour a day. Why, sometimes I’ve believed as many as six impossible things before breakfast.�. ...


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