Guanabenz resources


DRUG INFO
Guanabenz

Drug Name: Guanabenz

Indication: For management of High blood pressure



Pharmacology: Guanabenz, a centrally acting α-2 adrenergic agonist, is indicated for treatment of hypertension.

Mechanism Of Action: Guanabenz's antihypertensive effect is thought to be due to central alpha-adrenergic stimulation, which results in a decreased sympathetic outflow to the heart, kidneys, and peripheral vasculature in addition to a decreased systolic and diastolic blood pressure and a slight slowing of pulse rate. Chronic administration of guanabenz also causes a decrease in peripheral vascular resistance.

Drug Category: Sympatholytics; Antihypertensive Agents;

Brand Names/Synonyms: GBZ; Guanabenz; Guanabenz Acetate; Guanabenz [USAN:INN]; Guanabenzo [INN-Spanish]; Guanabenzum [INN-Latin]; HSDB 6535; Wy 8678; Wy 8678 base; Wy-8678; Wytensin; EINECS 225-750-8; Guanabenz(USAN)

Dosage Forms: Not Available

Absorption: Approximately 75% absorbed from gastrointestinal tract

Interactions: Not Available



Chemical IUPAC Name: (2,6-dichlorophenyl)methylideneaminoiminomethanediamine

Chemical Formula: C8H8Cl2N4

Half Life: 6 hours.

Drug Type: Approved Drug

# Accession No: APRD00487

CAS Registry Number: 5051-62-7



Guanabenz News
(When available)


Christmas tree pickup established at 3 parks  Dec 27, 2005
Beaumont Enterprise, Trees stripped of their stands, decorations and any plastics can be left at Rogers Park at Dowlen and Gladys; Sprott Park at Usan and Virginia; and Magnolia ...

Clemson 52, Winthrop 51  Dec 20, 2005
Gainesville Sun, ...usan Yenser's putback in the final second gave Clemson a 52-51 win over Winthrop on Tuesday night. The Lady Tigers (5-6) led 48-37 ...


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