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Glucagon recombinant
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DRUG INFO
Glucagon recombinant
Drug Name:
Glucagon recombinant
Indication: For treatment of severe hypoglycemia, also used in gastrointestinal imaging
Pharmacology: Used in the treatment of hypoglycemia and in gastric imaging, glucagon increases blood glucose concentration and is used in the treatment of hypoglycemia. Glucagon acts only on liver glycogen, converting it to glucose through the release of insulin. It also relaxes the smooth muscles of the gastrointestinal tract.
Mechanism Of Action: Glucagon binds the glucagon receptor which then initiates a dual signaling pathway using both adenylate cyclase activation and increased intracellular calcium. Glucagon receptors are found in the liver, kidney, brain and pancreatic islet cells. The glucagon mediated signals lead to an increase in insulin excretion
Drug Category: Antihypoglycemic Agents; glycogenolytic agents (68:22.12)
Brand Names/Synonyms: Glucagon precursor [Contains: Glicentin; Glicentin-related polypeptide;GRPP; Oxyntomodulin;OXY;OXM; Glucagon; Glucagon-like peptide 1;GLP-1; Glucagon-like peptide 1(7-37);GLP-1(7-37); Glucagon-like peptide 1(7-36);GLP-1(7-36); Glucagon-like peptide 2;GLP-2];Fragment; Glucagon (Eli Lilly); GlucaGen (Novo Nordisk)
Dosage Forms: KIT;POWDER FOR SOLUTION
Absorption: Not Available
Interactions: Not Available
Chemical IUPAC Name: Human Glucagon
Chemical Formula: C165H249N49O51S1
Half Life: Not Available
Drug Type: Approved Drug
# Accession No: BIOD00057
CAS Registry Number: 9007-92-5
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Glucagon recombinant News
(When available)
America's Weight Problem - Where Is The Pharmaceutical Industry? Dec 19, 2005
Medical News Today (press release), These anorectic hormones include; alpha-melanocyte-stimulating hormone (_-MSH)5, neurotensin6, and glucagon-like peptide-1 (GLP-1)7, etc. ...
Human Genome Sciences Receives Milestone Payment From ... Jan 10, 2006
Yahoo! News (press release) GSK reached in October 2004, under which GSK acquired exclusive worldwide rights to develop and commercialize GSK716155 (albumin-glucagon-like peptide-1, GLP-1 ...
Human Genome Sciences Reports on Progress Toward Commercialization ... Jan 10, 2006
PR Newswire (press release), PROGRESS OF OTHER PRODUCT OPPORTUNITIES GSK716155 (formerly known as Albugon), a novel long-acting form of glucagon-like peptide-1 (GLP-1) for use in the ...
The Skinny on Obesity Drugs Dec 22, 2005
Motley Fool 2008. Blocking DDP-IV allows natural levels of glucagon-like peptide-1 (GLP-1) to increase, thereby boosting satiety and fat loss. ...
Stimulation of pancreatic b-cell replication by incretins involves ... Dec 19, 2005
Journal of Endocrinology The incretin hormones, Glucagon-Like Peptide-1 (GLP-1) and Glucose-dependent Insulinotropic Peptide (GIP) have been suggested to act as b-cell growth factors ...
Exendin-4 induction of cyclin D1 expression in INS-1 b- cells ... Dec 22, 2005
Journal of Endocrinology Glucagon-like peptide-1 (GLP-1) and its analog exendin-4 (EX) have been considered as a growth factor implicated in pancreatic islet mass increase and ß-cell ...
Discovery Of Glucagon Secretion Mechanism May Lead To Improved ... Jan 14, 2006
Medical News Today (press release), A University of Toronto research team directed by Professor Qinghua Wang has discovered a mechanism for secretion of the hormone glucagon, which could ...
Human Genome Sciences Receives Milestone Payment From ... Jan 10, 2006
Yahoo! News (press release) ...with GSK reached in October 2004, under which GSK acquired exclusive worldwide rights to develop and commercialize GSK716155 (albumin-glucagon-like peptide-1 ...
No recess for diabetes Dec 17, 2005
Quincy Herald Whig, ...emergency. For instance, when a child's blood sugar level is dangerously low, a hormone called glucagon may need to be injected. ...
Human Genome Sciences Reports on Progress Toward Commercialization ... Jan 10, 2006
PR Newswire (press release), PROGRESS OF OTHER PRODUCT OPPORTUNITIES GSK716155 (formerly known as Albugon), a novel long-acting form of glucagon-like peptide-1 (GLP-1) for use in the ...
Why Blood Sugar Level Gets Out Of Balance In Diabetes - CARM1 ... Dec 22, 2005
Medical News Today (press release), Center (Deutsches Krebsforschungszentrum, DKFZ) have found out why specific genes are read as a response to hunger signals such as glucagon or glucocorticoids ...
America's Weight Problem - Where Is The Pharmaceutical Industry? Dec 19, 2005
Medical News Today (press release), These anorectic hormones include; alpha-melanocyte-stimulating hormone (_-MSH)5, neurotensin6, and glucagon-like peptide-1 (GLP-1)7, etc. ...
Ambulance rates to increase, electrical rates will follow Jan 3, 2006
The Caledonia Argus (subscription), ...medications and procedures, including aspirin and nitroglycerin for chest pain; cardiac defibrillation, albuterol for breathing problems, glucagon for low ...
Stimulation of pancreatic b-cell replication by incretins involves ... Dec 19, 2005
Journal of Endocrinology The incretin hormones, Glucagon-Like Peptide-1 (GLP-1) and Glucose-dependent Insulinotropic Peptide (GIP) have been suggested to act as b-cell growth factors ...
The Skinny on Obesity Drugs Dec 22, 2005
Motley Fool 2008. Blocking DDP-IV allows natural levels of glucagon-like peptide-1 (GLP-1) to increase, thereby boosting satiety and fat loss. ...
Exendin-4 induction of cyclin D1 expression in INS-1 b- cells ... Dec 22, 2005
Journal of Endocrinology Glucagon-like peptide-1 (GLP-1) and its analog exendin-4 (EX) have been considered as a growth factor implicated in pancreatic islet mass increase and ß-cell ...
Whole Grain Hogwash Dec 20, 2005
The Common Voice, ...without high levels of blood sugar your body continues to maintain stable levels of insulin, thus allowing the "fat burning" hormones, glucagon and growth ...
New Pharmaceutical Treatment Options in the Elderly Dec 14, 2005
Medscape (subscription) ...of glucose-dependent insulin secretion and several other antihyperglycemic actions of incretins, suppresses inappropriately elevated glucagon secretion, and ...
Can these hormones help to lose weight? Dec 19, 2005
Telegraph.co.uk, Oxyntomodulin: this gut hormone, which switches off appetite, might help people to lose weight, according to researchers at Imperial College London (ICL). ...
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