Indication: For management of manifestations of psychotic disorders.
Pharmacology: Fluphenazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Fluphenazine has not been shown effective in the management of behaviorial complications in patients with mental retardation.
Mechanism Of Action: Fluphenazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis.
Drug Category: Antipsychotics; Phenothiazines; ATC:N05AB02
Interactions:
DrugBank: Interactions for Fluphenazine
Interactions for Fluphenazine:
No information provided.
Chemical IUPAC Name: 2-[4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol
Chemical Formula: C22H26F3N3OS
Half Life: Not Available
Drug Type: Approved Drug
# Accession No: APRD00633
CAS Registry Number: 69-23-8
Fluphenazine News (When available)
CATIE Phase I Helps Clinicians Tailor Schizophrenia TreatmentJan 12, 2006 Psychiatric Times, ...on patients who discontinued their Phase II treatment and were given open treatment with clozapine, one of the atypicals, fluphenazine decanoate (Prolixin) or ...
Community Association Still Going Strong: Old Mystic group ...Dec 22, 2005 Shore Publishing, Since 1974, the OMCA's mission has been to “provide a closer association among the neighbors that are in the Stonington, Groton, Mystic area, and encourage ...
abLA "LA Picks for 2006"Jan 3, 2006 Art.Blogging.LA, ...we have to an LA-enniel or West Coast-enniel, I'm looking forward to seeing the artists chosen by Elizabeth Armstrong, Karen Moss (both from OMCA) and Rita ...
Study briefs, 1/03: Antipsychotics, kidney disease, foot soresJan 3, 2006 Lincoln Journal Star, The drugs included the conventional antipsychotics Tindal, Thorazine, Prolixin, Permitil, Serentil, Trilafon, Mellaril, Stelazine, Vesprin, Taractan, Haldol ...
CATIE Phase I Helps Clinicians Tailor Schizophrenia TreatmentJan 12, 2006 Psychiatric Times, ...who discontinued their Phase II treatment and were given open treatment with clozapine, one of the atypicals, fluphenazine decanoate (Prolixin) or dual ...
Study briefs, 1/03: Antipsychotics, kidney disease, foot soresJan 3, 2006 Lincoln Journal Star, The drugs included the conventional antipsychotics Tindal, Thorazine, Prolixin, Permitil, Serentil, Trilafon, Mellaril, Stelazine, Vesprin, Taractan, Haldol ...
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