Factor IX resources


DRUG INFO
Factor IX

Drug Name: Factor IX

Indication: For treatment of hemophilia (Christmas diseae)



Pharmacology: Binds vitamin K and factor VIIIa. Cleaves the Arg-Ile bond in factor X to form active factor Xa. Plays a key role in blood coagulation and clotting. Injections of factor IX are used to treat hemophilia B, which is sometimes called Christmas disease. AlphaNine is injected to increase plasma levels of Factor IX and can temporarily correct this coagulation defect.

Mechanism Of Action: Cleaves the Arg-Ile bond in Factor X to form active factor Xa leading to coagulation and clotting.

Drug Category: Coagulants; Thrombotic Agents; hemostatics (20:12.16)

Brand Names/Synonyms: Coagulation factor IX precursor;Christmas factor;Plasma thromboplastin component;PTC; Benefix (Genetics Institute)

Dosage Forms: LIQUID;POWDER FOR SOLUTION

Absorption: Not Available

Interactions: Not Available



Chemical IUPAC Name: Human factor IX protein

Chemical Formula: C2041H3136N558O641S25

Half Life: 17 to 32 hrs

Drug Type: Approved Drug

# Accession No: BIOD00038

CAS Registry Number: 9001-28-9



Factor IX News
(When available)


Wyeth opens Dublin drug discovery research facility  Dec 22, 2005
DrugResearcher.com, ...such innovative products as the rheumatoid arthritis drug Enbrel (etanercept), ReFacto (antihemophilic factor, recombinant), BeneFix (coagulation Factor IX ...


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