Indication: For treatment of moderate to severe vasomotor symptoms associated with the menopause, female hypogonadism, prostatic carcinoma-palliative therapy of advanced disease, breast cancer, as an oral contraceptive, and as emergency contraceptive.
Pharmacology: Ethinyl estradiol is a synthetic derivative of the natural estrogen estradiol. It is one of two estrogens currently used in oral contraceptive pills. The other, mestranol, is converted to ethinyl estradiol before it is biologically active. Ethinyl estradiol and norethindrone are used together as an oral contraceptive agent.
Mechanism Of Action: Estrogens diffuse into their target cells and interact with a protein receptor. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Estrogens increase the hepatic synthesis of sex hormone binding globulin (SHBG), thyroid-binding globulin (TBG), and other serum proteins and suppress follicle-stimulating hormone (FSH) from the anterior pituitary. The combination of an estrogen with a progestin suppresses the hypothalamic-pituitary system, decreasing the secretion of gonadotropin-releasing hormone (GnRH).
Absorption: Rapid and complete absorption follows oral intake of ethinyl estradiol (bioavailability 43%).
Interactions:
DrugBank: Interactions for Ethinyl Estradiol
Drug Interactions for Ethinyl Estradiol:
Certain endocrine and liver function tests may be affected by estrogen-containing oral contraceptives. The
following similar changes may be expected with larger doses of estrogen:
Increased sulfobromophthalein retention; increased prothrombin and factors VII, VIII, IX, and X; decreased
antithrombin 3; increased norepinephrine-induced platel et aggregation; increased thyroid binding globulin (TBG)
leading to increased circulating total thyroid hormone, as measured by PBI, T4 by column, or T4
by radioimmunoassay. Free T3 resin uptake is decreased, reflecting the elevated TBG; free T4
concentration is unaltered: impaired glucose tolerance; decreased pregnanediol excretion; reduced response to
metyrapone test; reduced serum folate concentration; increased serum triglyceride and phospholipid concentration.
Chemical IUPAC Name: 17-ethynyl-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
Chemical Formula: C20H24O2
Half Life: 36 +/- 13 hours
Drug Type: Approved Drug
# Accession No: APRD00691
CAS Registry Number: 57-63-6
Ethinyl Estradiol News (When available)
New year, new base payDec 31, 2005 Elmira Star-Gazette, ...increase. Paying higher wages does not reduce the cost of doing business in New York, said Mark Alesse, the federation's director. ...
Minimum wage hike goes into effect SundayDec 31, 2005 Poughkeepsie Journal, ..."Who this really hurts is entry-level workers because it makes it harder for them to find work," said Mark Alesse, the director of the group's New York office. ...
Pataki's State of State speech likely to be aimed outside NYJan 3, 2006 The Journal News.com, If there are new wrinkles, it could be a tax cut, said Mark Alesse, head of the state chapter of the National Federation of Independent Business, an umbrella ...
Small biz climate gets mixed reportsJan 5, 2006 Long Island Business News (subscription), Mark Alesse, state director of NFIB in New York says the state’s business climate, “one of the most expensive� in the country, prompts owners to have a ...
New year will bring minimum wage to $6.75Dec 22, 2005 Newsday, ..."I think it's going to hurt labor more than anything," said Mark Alesse, New York State director for the National Federation of Independent Business, which has ...
Even with pay hike, things are tough all overDec 26, 2005 Troy Record, Likewise, Mark Alesse, state director for the 1,500-member National Federation of Independent Businesses, said the increase will end up having an adverse ...
Zuniga tops exec chessJan 14, 2006 Tempo, Tied for fourth to sixth with identical 7 points were Randy Segarra, Efren Bagamasbad and Ed Sumergido. Alora ruled Group B with nine pointw to win P7,000. ...
First baby of 2006 arrives at JCHJan 5, 2006 Scottsboro Daily Sentinel, Both eight-year-old Alora and five-year-old Caitlin are little mothers to be, says the children’s mother, Michelle Terrell. Alora ...
The Village at the Lift Returns to Park CityJan 9, 2006 PR Newswire (press release), ...from brands including: James Jeans, Le Tigre, Pony, Pianegonda, Brics Luggage, Aquanautic Watches, Rocawear, Fredrick's of Hollywood, Alora Ambiance, Daniel ...
Exec chess finals setJan 3, 2006 Tempo, Group B - 1.Adler Enriquez 2. Ed Tunguia 3. Leoncio Maulion 4. Gary Baltar 5. Xavier Busig 6. Verth Alora 7. Jesurie Calabia 8. Rolando Gangozo 9. Francis ...
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Palmer High School unveils first-quarter honorsDec 27, 2005 The Republican, Bailey, Katie Boynton, Nicole Breault, James Daley, Jessica Gagne, Sarah Gagne, Milton Gancorz, Michael Gloster, Nicholas Graveline, Alora Heffernan, Alyssa ...
Memorial students receive surprise visitDec 12, 2005 Charlotte Sun-Herald, ...her entourage, and seven Memorial Elementary students -- Jacob Taylor, Esmeralda Calixtro, Dustin Yauilla, Makala Mulley, Caitlyn Lamb, Alora Gaskins and Joel ...
Climara Pro Receives US Approval for Osteoporosis PreventionJan 4, 2006 PharmaLive.com (press release), AG, Germany (FSE: SCH, NYSE: SHR) announced today that the Food and Drug Administration (FDA) has approved the hormone therapy patch, Climara Pro® (estradiol ...
FDA Approves Osteoporosis Indication for Once-a-Week Hormone ...Jan 4, 2006 PR Newswire (press release), Berlex, Inc., a US affiliate of Schering AG, Germany (FSE: SCH; NYSE: SHR), announced today that the FDA has approved the hormone therapy patch, Climara Pro(R ...
FDA OK's Berlex hormone patchJan 4, 2006 United Press International WAYNE, NJ, Jan. 4 (UPI) -- Berlex said Wednesday it has been cleared to market its Climara Pro hormone patch to prevent osteoporosis. ...
Schering Drug Approval To Have Minor ImpactJan 5, 2006 New Ratings 0841 GMT [Dow Jones] The approval by the FDA of Schering's (SHR) Climara Pro therapy patch for postmenopausal osteoporosis should only result in limited ...
Berlex says FDA clears hormone therapy patchJan 4, 2006 Reuters ...affiliate of Germany's Schering AG (SCHG.DE: Quote, Profile, Research), said on Wednesday that the FDA had approved its hormone therapy patch, Climara Pro, for ...
Schering gets wider approval for patchJan 4, 2006 BusinessWeek 4 8:19 AM ET Germany's Schering AG said Wednesday that US regulators broadened the approval of its Climara Pro hormone patch to include its use for preventing ...
Schering gets FDA OK on hormone patchJan 4, 2006 CNN/Money NEW YORK (Reuters) - Germany's Schering said on Wednesday that the US Food and Drug Administration had approved its hormone therapy patch, Climara Pro, for the ...
Berlex Skin Patch Approved For New UseJan 4, 2006 Business New Jersey (subscription), The patch, called Climara Pro, has been on the market since 2003 as a treatment for women with undamaged uteruses who exhibit vasomotor symptoms such as night ...
Schering "underperform"Jan 5, 2006 New Ratings In a research note published this morning, the analyst mentions that the company has announced that it has received the FDA approval for Climara Pro in the US ...
Highlights of rising and falling US stocksJan 4, 2006 Investor's Business Daily (subscription) ...said Wednesday the Food and Drug Administration approved hormone therapy patch Climara Pro for the prevention of postmenopausal osteoporosis. ...
European Indexes in the Black at MiddayJan 4, 2006 BusinessWeek Schering's (SHR )(-0.19%) US affiliate Berlex said that the FDA had approved its hormone therapy patch, Climara Pro, for the prevention of postmenopausal ...
Willie J. WashingtonJan 13, 2006 Greenwood Commonwealth, He is survived by his wife, Genora Jones Washington of Moorhead; 11 daughters, Willie Mae Meeks and Genora Springfield, both of East St. ...
Around the CountiesJan 5, 2006 Louisville Courier-Journal, 16. For ticket information, call Genora Birdsong at 218-3472 or Saundra Couts at 493-1917. A town hall meeting with host state Sen. ...
The Purcell RegisterDec 22, 2005 Purcell Register, He was preceded in death by his parents; one sister, Velda; three brothers, Haskell, Harold and Hubert Newville; one sister-in-law, Genora Newville; a brother ...
Emancipation event to honor 14 womenDec 24, 2005 Athens Banner-Herald (subscription), Lucille Law of Commerce; Mary Lay of Statham; Lucille Cooper of Jefferson; attorney Janice Mathis and Sebelle Jordan of Bogart; 94-year-old Genora Hamm Biggs ...
Citizen of the Year: Dave Jenest, Conservative ActivistDec 28, 2005 Town Hall, Dave Jenest is one of the unsung heroes of the conservative movement. He is known in his community as the local “watchdog� for more reasons than one. ...
2005 Citizens of the Year: The Iraqi PeopleDec 29, 2005 Town Hall, We've run extensive features on our three finalists (The Minutemen Project, Congressmen Mike Pence, and Dave Jenest) this week and received a great deal of ...
Schering Drug Approval To Have Minor ImpactJan 5, 2006 New Ratings Believes Schering's Menostar remains the more attractive drug for the indication because it delivers a lower hormone dosage than Climara Pro. ...
BARR PHARMACEUTICALS: Barr Pharmaceuticals Financial OutlookJan 5, 2006 Webbolt Business News (subscription), Health, LLC and its ParaGard(R) IUD; (2) the potential impact of its non-binding Letter of Intent to acquire the exclusive rights to Organon's Mircette(R) oral ...
CAAN to release Necon's aircraftDec 21, 2005 Kathmandu Post, KATHMANDU, Dec 21 - Civil Aviation Authority of Nepal (CAAN) has agreed to release two aircraft leased by Necon Air, kept unused at Tribhuwan International ...
CAAN annuls registeration of Necon aircraftDec 21, 2005 Kantipur Online, KATHMANDU, Dec 22 - Civil Aviation Authority of Nepal (CAAN) has annulled the registration of two airplanes belonging to Necon Air, kept unused at Tribhuwan ...
Government Cancels Registration of Necon's AircraftDec 22, 2005 NewsLine Nepal, The Civil Aviation Authority of Nepal (CAAN) has cancelled the registration of two airplanes belonging to Necon Air that were abandoned at Tribhuwan ...
CAAN annuls registration of Necon AirDec 21, 2005 Nepalnews.com, The Civil Aviation Authority of Nepal (CAAN) has annulled the registration of two airplanes of Necon Air kept unused at Tribhuvan International Airport for the ...
Neocon Muslims: nuisance or threatDec 27, 2005 Milli Gazette, ...campaigns are ignored. America’s necon masters are also busy stigmatizing the distinct identity of the Muslims. Pejorative comments ...
Brig. Gen. Mohammed Buba MarwaDec 26, 2005 Daily Sun, Investigations further showed that the late Head of State thereafter directed the then National Electoral Commission of Nigeria (NECON) to order for the same ...
Infrastructure boom waiting in the wingsJan 8, 2006 Moneyweb, Wilson Bayly Holmes Ovcon chairman Mike Wylie, said in the company's latest annual report, "All indications are that buoyant conditions in the industry should ...
Exploring The Alternatives16 Jan 2006 Saturday Evening Post, One form of chelation therapy, EDTA (ethylenediamine tetra-acetic acid)--a synthetic, or man-made, amino acid--is delivered intravenously and, as practiced in ...
Excise Duty On Bottled Water Squeezes Keringet's Margins16 Jan 2006 AllAfrica.com, ...bottled water. The juice market is a crowded field with local and imported brands, tetra-packed juices and the fresh products. Besides ...
Blade stock contest in full swing16 Jan 2006 Toledo Blade, Diane Jacobson, 60, of Findlay, chose an eclectic portfolio consisting of Gamestop Corp., a video and entertainment-software firm; Tetra Technologies Inc., an ...
TETRA TECHNOLOGIES: Announces 2006 Earnings GuidanceJan 9, 2006 Webbolt Business News (subscription), By MM - Webbolt Newsroom. TETRA Technologies, Inc. ... The low end of the range approximately doubles analysts' current estimates of TETRA's 2005 earnings. ...
EADS signs three major contracts for delivery of TETRA terminalsJan 9, 2006 noticias.info, .../noticias.info/ EADS has received three major contracts delivering its TETRA secure communications terminals to the Belgian fire brigades, to the Irish police ...
Tetra Tech gets deals worth up to $88.5MJan 5, 2006 BusinessWeek 5 4:16 PM ET Tetra Tech Inc., a provider of environmental cleanup services, management and consulting, said Thursday it received two contracts worth a total of ...
Tetra Technologies upgraded to "buy"Jan 6, 2006 New Ratings NEW YORK, January 6 (newratings.com) – Analyst Martin W Malloy of Hibernia Southcoast Capital upgrades Tetra Technologies Inc (TTI.NYS) from "hold" to "buy ...
TETRA Technologies, Inc. Announces 2006 Earnings GuidanceJan 5, 2006 Business Wire (press release), 5, 2006--TETRA Technologies, Inc. (TETRA or the Company) (NYSE:TTI) today announced earnings guidelines for 2006 of $2.09 - $2.35 per diluted share. ...
Tetra Tech Awarded $48.5 Million US EPA START Region 4 ContractJan 5, 2006 Finanzen.net, Tetra Tech, Inc. ... We are very pleased that EPAselected Tetra Tech again to lead the critical Region 4 START programas we have done during the past 10 years. ...
Tetra Tech awarded $48.5 Million US EPA START Region 4 contractJan 6, 2006 Construction and Maintenance News, Tetra Tech, Inc. ... Under the previous contract, Tetra Tech continues to support EPA by performing hurricane response work in the Gulf Coast region. ...
Motorola, T-Systems, R&S deploy TETRA in HamburgJan 5, 2006 Telecom Paper (subscription), The network is based on the mobile radio standard TETRA. As one of the first deployments, the partners will cover Hamburg with a ...
Interxion hosts MCCN TETRA networkDec 20, 2005 Telecom Paper (subscription), ...has chosen the provider of carrier-neutral data centre and managed services in Europe, Interxion, to host the switching and management hub of its TETRA network ...
Tetra Tech Gets Deals Worth Up to $88.5MJan 5, 2006 MSN Money PASADENA, Calif. (AP) - Tetra Tech Inc., a ... The new contract combines an existing contract Tetra Tech has had with the agency for years, the company said. ...
Tetra Tech Gets Deals Worth Up to $88.5M (AP)Jan 5, 2006 Schaeffers Research, Tetra Tech Inc., a provider of environmental cleanup services, management and consulting, said Thursday it received two contracts worth a total of up to $88.5 ...
Residents are wise to voice phone mast fearsJan 13, 2006 Hampstead and Highgate Express, Sir William Stewart in his two reports on mobile phone masts, and TETRA have repeatedly recommended a precautionary approach and further research, but in over ...
Blacksburg firm sues fish supply firm in Fla.Jan 4, 2006 Roanoke Times, Tetra Holding Inc. of Blacksburg ... of Dania, Fla., for $200,942.72, the full amount Tetra claims it is owed for the products. Tetra's Blacksburg ...
Sepura wins 'Stage One' Security Approval in UKJan 10, 2006 Telecom Paper (subscription), Sepura radios are the first and only TETRA radios so far in the United Kingdom to be awarded 'Stage One' Security Approval by the UK Government's ...
Angry OAPs lose TV signalJan 12, 2006 Exmouth Journal, They say interference problems began in the autumn - around the same time the police switched to a new Tetra digital radio system.
Group to assess risks of pylons and radiationJan 11, 2006 Edinburgh Evening News, ...to meet to discuss the risk to public health of electricity pylons and other radiation-emitting sources such as the new generation of Tetra communication masts ...
Amul may witness 50% increase in exportsJan 13, 2006 Sify, ...countries during the year. The product range includes butter, cheese, srikhand, gulab-jamuns, paneer and tetra pack milk. Ice-creams are ...
Find Out The Truth About Oral Chelation TherapyJan 5, 2006 PR Web (press release), This is accomplished by administering an amino acid, ethylene-diamine-tetra-acetic acid (EDTA), by an intravenous infusion using a small 25-gauge needle. ...
Contracted service costs too much, official saysJan 5, 2006 The Grand Rapids Press, ...the city is "spending more money (rather) than less money" for contracted treatment plant operations, Bowers voted against extending Tetra Tech MPS's pact ...
Sweet Success to initiate production of Powerblend beverageJan 12, 2006 Food Ingredients First (press release), ...in Savannah, GA. Powerblend will come packaged in 330ml (11 ounce) aseptic Tetra Prisma containers packaged as four-packs. It is ...
So many SamsJan 13, 2006 Indian Express, He first founded the Tetra Society, which recruits technically-skilled volunteers to contrive assistive devices for disabled people. ...
What to do instead of detoxJan 2, 2006 ic Wales, ...some cold meats to throw together at lunchtime. And make smoothies at weekends rather than drinking squash or Tetra-packed juices.
Friendly Bacteria at WorkJan 1, 2006 Natural Life, A group of 181 workers at a Tetra Pak factory in Lund, Sweden were randomly assigned to receive a drink with or without L. reuteri, every day for a period of ...
Review of the Year: Part II (May-August)Dec 28, 2005 Siliconrepublic.com, The Garda SÃochána signalled its intentions to move into the world of Tetra (Terrestrial Trunked Radio) and issued a tender for 100, rising to possibly 150 ...
Sepura signs partnership with BESCom ElektronikDec 22, 2005 Telecom Paper (subscription), UK-based TETRA radio supplier Sepura has signed a partnership agreement with German systems integrator BESCom Elektronik. BESCom ...
45 and Counting: Turn up the volumeDec 27, 2005 Fauquier Times-Democrat, Tetra Nova, a rock band featuring RJ Haynes, Zack Hale, Doug Sherman and Brian Brower, ushered in the crowd. Haynes is well-known to the Liberty community. ...
Updates, advisories and surprisesJan 5, 2006 Investor's Business Daily (subscription) The stock closed Wednesday at $51.63, down 19 cents. Tetra Tech sees 2006 earns above Wall St. view (8:53 AM ET) NEW YORK (MarketWatch ...
The Winchester StarJan 11, 2006 Winchester Star, Tetra Partnerships, a Reston-based real estate and development company, has purchased commercial real estate property in the industrial park, Barker said. ...
Experts say dust plumes at mine caused by more than windJan 12, 2006 Reno Gazette Journal, Elaborating on some interesting findings so far, Douglas Herlocker, environmental scientist/senior air quality specialist of Tetra Tech EM, Inc., spoke during ...
Cloning MilestonesJan 10, 2006 Fact Monster, 1999 Dr. Gerald Schatten (US) leads a team of researchers who become the first to create a clone (Tetra, a rhesus monkey) by embryo splitting. ...
Amul ready to take on Pepsi, Coke in sports drink segmentJan 10, 2006 Financial Express, With lemon flavour, it will be available in Tetra Paks and is priced at Rs 12(for 200 ml). Two years ago, we entered flavoured milk segment,"said Mr Sodhi. ...
Noga plans new unit in food parkJan 1, 2006 Business Standard, Two years ago, MAIDC had acquired three acres of land for setting up a tetra pack unit in the food park. The plan was, however, shelved ...
Council sets hearing on utility rate hikesJan 12, 2006 Ann Arbor News, As Chelsea prepares to expand its wastewater treatment plant, Tetra Tech MPS was unanimously chosen Tuesday night by the Chelsea City Council to prepare ...
Inmarko fully placed primary bond issue.Dec 23, 2005 Analytical Information Agency, Inmarko ice cream is manufactured under high-end European technologies using state-of-the-art equipment of GRAM, Tetra Pak, APV, GEA. ...
Backwash storage tank project moving along in MCDec 21, 2005 New Baltimore Voice Newspapers, ..."Construction is underway, the steel sheeting is in place, it's temporary, the excavation is complete,“ said Ken Kingsley of Tetra Tech MPS, the project ...
Preview: People in PlanesDec 21, 2005 ic Wales, FRESH from touring the UK with The Crimea and America with The Bravery, local heroes People In Planes (formerly known as Tetra Splendour) are back in Clwb Ifor ...
Stocks Tread Water Despite Jump In VolumeJan 3, 2006 Investor's Business Daily (subscription) ...from $50. Other movers in the group included Tetra Technologies (TTI), Oil States International (OIS) and Schlumberger (SLB). The ...
Kenya Switches to Unleaded FuelJan 3, 2006 AllAfrica.com, ...enhancement additives. The refineries previously added tetra-ethyl lead to petrol to improve its anti-knocking capabilities. Under ...
TURIN 2006: FOCUS; AIR SHIELD AND 9,000 SECURITY PERSONNELJan 2, 2006 ansa.it, Communications between the security forces will be guaranteed by the new 'Tetra' system: instead of the old radios, digital devises similar to mobile ...
Death of 5-year-old boy linked to controversial chelation therapyJan 5, 2006 Pittsburgh Post Gazette, In layman's terms, the administration of ethylene diamine tetra-acetate, commonly known as chelation, resulted in a lack of oxygen to the brain as well as ...
Analyst RatingsJan 8, 2006 Asbury Park Press, StealthGas Inc. (GASS) was rated new "outperform" in new coverage by analyst J. Michael Drickamer at Morgan Keegan. Tetra Technologies Inc. ...
New drinks review: a colorful approach to cocktail presentationJan 3, 2006 Drinks Business Review The punch comes in a compact package design so that it can be easily stored and which is microwave safe. It also has a resealable quick-peel Tetra top. ...
Playground SafetyJan 4, 2006 Child Care Business Magazine, A number of material choices are available in today’s market, including Teflon-coated fiberglass or PTFE, Hybrid forms of PTFE, Ethylene tetra ethylene (ETFE ...
Rockabilly non-revivalJan 6, 2006 Jerusalem Post, When Bill Flag was working on his seminal Tetra Records sessions in 1955 and 1956, he named the style "rockabilly," and the name stuck. ...
The Legend of Zelda: The Wind WakerJan 6, 2006 IGN, Take that PigDemon!) the pirates on the island help you out to go rescue your sister. It seems Link has another girlfriend, Tetra. ...
Rasna Juc FitJan 6, 2006 Chennai Online, ...build a brand. The 200 ml tetra pack of Rasna Juc Fit will be available for Rs 10 while the one litre pack comes at Rs 45. Rasna Pvt ...
Fitness in's and out'sDec 31, 2005 INQ7.net, ...from the production process, packaging and others. The multinational Tetra Pak has set up collection. points in a growing number of ...
Remember the three Rs during the holidays: council appealDec 29, 2005 Meath Chronicle, ...are in Navan and Trim, where householders can bring a wide range of materials including Christmas cards, Christmas trees, wrapping paper, Tetra Pak cartons ...
Laois people urged to do their bit to have a greener ChristmasDec 22, 2005 Laois Nationalist, ...visit the civic amenity site at Kyletalesha Landfill in Portlaoise - where everything from plastic bottles, aluminium cans, cardboard, glass and Tetra Pak can ...
Peak of the Market soups ready for store shelvesDec 19, 2005 Brandon Sun, But for now, the $3.99 soups — sold in one-litre tetra packs — are available in Winnipeg at Dakota Family Foods, Lorenzo’s Speciality Foods, the three ...
APPMA Announces Top Six Pet Industry Trends for '06Dec 28, 2005 Business Wire (press release), Inc. (formerly Rayovac Corp.) recently acquired Tetra, a privately held fish product supplier; Central Garden & Pet Co. purchased ...
Tour de grottoDec 22, 2005 San Antonio Current, Today, only goldfish and Tetra swim around in the pool, but I can identify with that prankster urge. Around the back of the grotto, there's an empty niche. ...
