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Digoxin Immune Fab
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DRUG INFO
Digoxin Immune Fab
Drug Name:
Digoxin Immune Fab
Indication: For treatment of digitoxin overdose or digitalis glycoside toxicity
Pharmacology: DigiFab binds molecules of digoxin, making them unavailable for binding at their site of action on cells in the body. The Fab fragment-digoxin complex accumulates in the blood, from which it is excreted by the kidney. The net effect is to shift the equilibrium away from binding of digoxin to its receptors in the body, thereby reversing its effects
Mechanism Of Action: Binds excess digoxin or digitoxin molecules circulating in the blood.
Drug Category: Digoxin Antidote; serums (80:04.00)
Brand Names/Synonyms: DigiFab
Dosage Forms: POWDER FOR SOLUTION
Absorption: Not Available
Interactions: Not Available
Chemical IUPAC Name: Anti-digoxin antibody fragment
Chemical Formula: C2085H3223N553O672S16 >26-10 Light chain (murine)
Half Life: 15-20 hrs
Drug Type: Approved Drug
# Accession No: BIOD00046
CAS Registry Number: Not Available
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Digoxin Immune Fab News
(When available)
Kevin Goldstein-Jackson: The drugs start to kick in at last Dec 16, 2005
Financial Times, The original attraction to me of Protherics was that as well as its Digifab treatment for digoxin toxicity and its highly successful CroFab treatment for ...
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