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Digibind
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DRUG INFO
Digibind
Drug Name:
Digibind
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Indication: For treatment of digitoxin overdose or digitalis glycoside toxicity
Pharmacology: DigiFab binds molecules of digoxin, making them unavailable for binding at their site of action on cells in the body. The Fab fragment-digoxin complex accumulates in the blood, from which it is excreted by the kidney. The net effect is to shift the equilibrium away from binding of digoxin to its receptors in the body, thereby reversing its effects.
Mechanism Of Action: Binds excess digoxin or digitoxin molecules circulating in the blood.
Drug Category: Digoxin Antidote
Brand Names/Synonyms: Ig gamma-2A chain C region, A allele; DigiBind
Dosage Forms: Not Available
Absorption: Not Available
Interactions: Not Available
Chemical IUPAC Name: Anti-digoxin antibody fragment
Chemical Formula: C6394H9908N1698O2011S58 >Anti-digoxin 26-10 Light chain 1 >Anti-digoxin 26-10 Heavy chain 2 >Anti-digoxin 26-10 Light chain 2
Half Life: 1 hours (mammalian reticulocytes, in vitro)
Drug Type: Approved Drug
# Accession No: BIOD00027
CAS Registry Number: Not Available
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