Desmopressin resources


DRUG INFO
Desmopressin

Drug Name: Desmopressin

Indication: For the management of primary nocturnal enuresis and indicated as antidiuretic replacement therapy in the management of central diabetes insipidus and for the management of the temporary polyuria and polydipsia following head trauma or surgery in the pituitary



Pharmacology: Desmopressin is a synthetic analogue of the natural pituitary hormone 8-arginine vasopressin (ADH), an antidiuretic hormone affecting renal water conservation. Desmopressin is indicated as antidiuretic replacement therapy in the management of central diabetes insipidus and for the management of the temporary polyuria and polydipsia following head trauma or surgery in the pituitary region and is also indicated for the management of primary nocturnal enuresis.

Mechanism Of Action: Desmopressin emulates the actions of the natural pituitary hormone 8-arginine vasopressin (ADH).

Drug Category: Renal Agents; Hemostatics (20:12.16); Pituitary (68:28.00); ATC:H01BA02

Brand Names/Synonyms: DESMOPRESSIN; Desmopresina [INN-Spanish]; Desmopressine [INN-French]; Desmopressinum [INN-Latin]; 1-Deamino-8-D-arginine vasopressin; 1-Desamino-8-D-arginine vasopressin; 1-Desamino-8-d-arginine-vasopressin; Desamino-8-D-arginine vasopressin, l-; Concentraid; DDAVP; Stimate

Dosage Forms: TABLET

Absorption: Not Available

Interactions: Interactions for Desmopressin: Although the pressor activity of Desmopressin is very low compared to its antidiuretic activity, large doses of Desmopressin Tablets should be used with other pressor agents only with careful patient monitoring.



Chemical IUPAC Name: 1-[[13-benzyl-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-4-yl]carbonyl]-N-[1-(carbamoylmethylcarbamoyl)-4-guanidino-butyl]-pyrrolidine-2-carboxamide

Chemical Formula: C46H64N14O12S2

Half Life: 1.5-2.5 hours

Drug Type: Approved Drug

# Accession No: BIOD00112

CAS Registry Number: 16679-58-6



Desmopressin News
(When available)



Teva Announces Approval of Desmopressin Acetate Tablets  Jan 29, 2006
...(Nasdaq: TEVA) announced today that the US Food and Drug Administration has granted final approval for the Company's ANDA for Desmopressin Acetate Tablets, 0.1 ... - International News Service,

FDA approval for Teva's desmopressin acetate tablets  Jan 29, 2006
...the US Food and Drug Administration (FDA) has granted final approval for the company's abbreviated new drug application (ANDA) for desmopressin acetate tablets ... - Globes,

Desmopressin improves nighttime urination in men  Jan 17, 2006
NEW YORK (Reuters Health) - Desmopressin safely relieves frequent nighttime urination or "nocturia" in elderly men who've tried other medications to control ... - Reuters.uk,

Ranbaxy to sell Swiss Ferring's Desmopressin in India  Jan 10, 2006
...said on Tuesday it struck a marketing deal with Swiss biopharma company Ferring International to sell hormone tablet Desmopressin in India. ... - Reuters India,

Barr reports strong quarterly earnings  Feb 8, 2006
The rise in overall generic sales was largely attributable to Barr's introductions of its versions of desmopressin, used to treat bed wetting and frequent ... - The Journal News.com,

Barr Reports Second Quarter Fiscal 2006 GAAP Earnings of $0.88 Per ...  Feb 7, 2006
The $24 million increase is primarily related to strong sales of the Company's Desmopressin product that was launched in July 2005 and sales of its Didanosine ... - PR Newswire (press release),

Drug improves nighttime urination in men  Jan 17, 2006
NEW YORK, JANUARY 18 : Desmopressin safely relieves frequent nighttime urination or "nocturia" in elderly men who've tried other medications to control their ... - Financial Express,

Barr Should Get Earnings Boost From Key Drugs  Feb 6, 2006
...from the lack of additional generic market competition and an extended period of market exclusivity for its generic version of DDAVP (desmopressin acetate). ... - TheStreet.com

Ranbaxy signs mktg deal with Ferring Intl  Jan 10, 2006
Ranbaxy Laboratories has signed a co-marketing agreement with Switzerland-based Ferring International for marketing Ferring's Desmopressin. ... - Business Standard,

Ranbaxy gets into mktg agreement with Swiss Company  Jan 10, 2006
...maker Ranbaxy Laboratories today signed a co-marketing agreement with Switzerland-based Ferring International for marketing Ferring’s Desmopressin as part of ... - NewKerala.com,

Ranbaxy to co-market Ferrings` urology drug  Jan 10, 2006
...into a co-marketing agreement with Switzerland-based Ferring International, a speciality biopharmaceutical company, for the latter’s product Desmopressin. ... - Business Standard,

RANBAXY: Ranbaxy To Co-Market Ferring's Urology Drug In India ...  Jan 11, 2006
...into a co-marketing agreement with Ferring International of Switzerland, a speciality biopharmaceutical company, for its product Desmopressin, a structural ... - Webbolt Business News (subscription),

Ranbaxy ties up with Swiss Co to sell its drug in India  Jan 10, 2006
Mumbai: Ranbaxy has signed a co-marketing agreement with Swiss company Ferring International for selling its drug Desmopressin in the country under the brand ... - NewKerala.com,

Ranbaxy enters into co-marketing agreement with Swizz co  Jan 10, 2006
Tuesday entered into a co-marketing agreement with Switzerland-based Ferring International, a specialty biopharmaceutical company, for its product Desmopressin ... - Hindustan Times,

Ranbaxy enters into agreement with Ferring International ...  Jan 10, 2006
Laboratories (Q, N,C,F)* Ltd has entered into a co-marketing agreement with Ferring International of Switzerland, for its product Desmopressin, a structural ... - Myiris.com,

Ranbaxy signs co-marketing pact with Ferring 1/10/2006 1:49:45 PM ...  Jan 10, 2006
...that it has entered into a co-marketing agreement with Ferring International of Switzerland, a specialty biopharmaceutical company, for its product Desmopressin ... - India Infoline.com,

Ranbaxy in co-marketing agreement with Ferring of Switzerland  Jan 10, 2006
...entered into a co-marketing agreement with Ferring International of Switzerland, a specialty biopharmaceutical firm, for its product Desmopressin; a structural ... - domain-B,

Sensex slides 138 points  Jan 10, 2006
...gained 4 per cent after the company said it had struck a marketing deal with Swiss company Ferring International to sell hormone tablet Desmopressin in India. ... - Business Standard,

Indian shares fall ahead of Reliance  Jan 10, 2006
...to 393.75 rupees after it said it had struck a marketing deal with Swiss biopharma company Ferring International to sell hormone tablet Desmopressin in India. ... - Reuters India,

Wrap up: Sensex slumps 138 points  Jan 10, 2006
...on the news that the company has entered into a co-marketing agreement with Ferring International of Switzerland, for its product Desmopressin, a structural ... - Myiris.com,

Ranbaxy Year 2005 Global Sales at USD 1178 Mn  Jan 18, 2006
Recently the Company entered into a co-marketing agreement with Ferring International of Switzerland, for its product Desmopressin, The in-licensing agreement ... - PharmaLive.com (press release), Transcript of Paul Posluszny/Levi Brown Press Conference  Jan 13, 2006
GoPSUsports.com I wear this brace and do exercises here and there and a lot of therapy sitting in a cold tub and getting stim and ultrasound put on my knee and things like that ...

State Taking Applications For Training Program  Jan 6, 2006
Hartford Courant, Project manager Ed Stim said the companies also must have billed at least $500,000 in contracts during the preceding 24-month period. ...

Ten best career books for 2005  Jan 2, 2006
Sun-Sentinel.com, ...more volatile. Whoops! I'm in Business: A Crash Course in Business Basics by Richard Stim and Lisa Guerin (Nolo). Readers who savor ...

Unreal Tournament 2004  Dec 18, 2005
4players, Any music with "AllowStim" at the end of the song title can be played alongside a Stim. No longer able to carry two SIZE_Large items. ...

Inflation drops marginally to 4.5 percent  Dec 23, 2005
Webindia123, 4.77 per cent for the week ended October 15, from provisional 4.71 per cent, while WPI stood corrected at 197.8 points as against the earlier stimate of 197.7 ...

Weekly wrap up: Sensex sheds 266 points  Jan 14, 2006
Myiris.com, ...marketing agreement with Ferring International of Switzerland, for its product Desmopressin, a structural analogue of the pituitary hormone arginine vasopressin ...

Ranbaxy to co-market Ferrings` urology drug  Jan 10, 2006
Business Standard, Desmopressin, a structural analogue of the pituitary hormone Arginine Vasopressin, is an original research product of Ferring International. ...

Ranbaxy enters into co-marketing agreement with Swizz co  Jan 10, 2006
Hindustan Times, The product, a structural analogue of the pituitary hormone Arginine Vasopressin, is indicated in the treatment of Nocturia, a condition commonly seen in ...

RANBAXY: Ranbaxy To Co-Market Ferring's Urology Drug In India ...  Jan 11, 2006
Webbolt Business News (subscription), ...of Switzerland, a speciality biopharmaceutical company, for its product Desmopressin, a structural analogue of the pituitary hormone Arginine Vasopressin. ...

Ranbaxy ties up with Swiss Co to sell its drug in India  Jan 10, 2006
NewKerala.com, Desmopressin is a structural analogue of the pituitary hormone arginine vasopressin and is indicated in the treatment of nocturia, a condition commonly seen in ...

FDA Approves Astellas' VAPRISOL(R) For The Treatment Of Euvolemic ...  Dec 30, 2005
PR Newswire (press release), FDA) has approved VAPRISOL(R) (investigational name: YM087, generic name: conivaptan hydrochloride injection), an arginine vasopressin (AVP) antagonist for the ...

Ranbaxy in co-marketing agreement with Ferring of Switzerland  Jan 10, 2006
domain-B, ...of Switzerland, a specialty biopharmaceutical firm, for its product Desmopressin; a structural analogue of the pituitary hormone arginine vasopressin. ...

FDA Approves Astellas' VAPRISOL(R) For The Treatment Of Euvolemic ...  Dec 30, 2005
PR Newswire (press release), First arginine vasopressin (AVP) antagonist approved for the management of potentially life-threatening sodium/water imbalance DEERFIELD, Ill., Dec. ...


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