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Chlorothiazide
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DRUG INFO
Chlorothiazide
Drug Name:
Chlorothiazide
Indication: Chlorothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension.
Pharmacology: Like other thiazides, chlorothiazide promotes water loss from the body (diuretics). It inhibits Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue. Chlorothiazide affects the distal renal tubular mechanism of electrolyte reabsorption. At maximal therapeutic dosages, all thiazides are approximately equal in their diuretic efficacy. Chlorothiazide increases excretion of sodium and chloride in approximately equivalent amounts. Natriuresis may be accompanied by some loss of potassium and bicarbonate.
Mechanism Of Action: As a diuretic, chlorothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like chlorothiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter. This results in an increase in potassium excretion via the sodium-potassium exchange mechanism. The antihypertensive mechanism of chlorothiazide is less well understood although it may be mediated through its action on carbonic anhydrases in the smooth muscle or through its action on the large-conductance calcium-activated potassium (KCa) channel, also found in the smooth muscle.
Drug Category: Diuretics, Thiazide; Antihypertensive Agents; ATC:C03AA03; ATC:C03AA04
Brand Names/Synonyms: Aldoclor; Alurene; CT; Chloriazid; Chlorosal; Chlorothiazid; Chlorothiazide; Chlorthiazide; Chlortiazid; Chlorurit; Chlotride; Chlrosal; Clotride; Diupres; Diuresal; Diuril; Diuril Boluses; Diuril Lyovac [As Sodium Salt]; Diurilix; Diurite; Diutrid; Esidrix; Flumen; Hydro-D; Hydrochlorothiazide; Hydrochlorothiazide Intensol; Hydrodiuril; Lyovac Diuril [As Sodium Salt]; Microzide; Minzil; Neo-Dema; Oretic; Salisan; Salunil; Saluretil; Saluric; Sk-Chlorothiazide; Thiazide; Urinex; Warduzide; Yadalan; Zide
Dosage Forms: TABLET (250, 500 mg)
Absorption: Not Available
Interactions: Interactions for Chlorothiazide:
When given concurrently the following drugs may interact with thiazide diuretics.
- Alcohol, barbiturates, or narcotics: Potentiation of otthostatic hypotension may occur.
- Antidiabetic drugs: (Oral agents and insulin) Dosage adjustment of the antidiabetic drug may be required.
- Other antihypertensive drugs: Additive effect or potentiation.
- Cholestyramine and colestipol resins: Cholestytamine and colestipol resins have the potential of binding thiazide diuretics and reducing diuretic absorption from the gastrointestinal tract.
- Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia.
- Pressor amines (e.g., norepinephrine): Possible decreased response to pressor amines but not sufficient to preclude their use.
- Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine): Possible increased responsiveness to the muscle relaxant.
- Lithium: Generally should not be given with diuretics. Diuretic agents reduce the renal clearance of lithium and add a high risk of lithium toxicity. Refer to the package insert for lithium preparations before use of such preparations with chlorothiazide.
- Non-steroidal Anti-inflammatory Drugs: In some patients, the administration of a non-steroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. Therefore, when chlorothiazide and non-steroidal anti-inflammatory agents are used concomitantly, the patient should be observed closely to determine if the desired effect of the diuretic is obtained.
- Drug/Laboratory Test Interactions: Thiazides should be discontinued before carrying out tests for parathyroid function.
Chemical IUPAC Name: 9-chloro-5,5-dioxo-5$l^{6}-thia-2,4-diazabicyclo[4.4.0]deca-3,6,8,10-tetraene-8-sulfonamide
Chemical Formula: C7H6ClN3O4S2
Half Life: 45-120 minutes
Drug Type: Approved Drug
# Accession No: APRD00721
CAS Registry Number: 58-94-6
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Chlorothiazide News
(When available)
Detecting "Masked" Hypertension 16 Jan 2006
Saturday Evening Post, Appetizers: enjoy low-fat crackers and cheese, and fresh vegetables with a healthy yogurt dip mixed with dill, basil, or pre-mixed low-sodium seasonings. ...
Nutrition Notes: Men: What Eating Group Are You In? 16 Jan 2006
Kansas City infoZine, Their excessive sodium intake (from many processed foods) and low potassium intake (from few vegetables and fruits) are probably related. ...
Judges deny Allen's appeal -- reprieve sought Supreme Court last ... 16 Jan 2006
San Francisco Chronicle, Sodium pentothal will put him to sleep, pancuronium bromide will stop his breathing, and potassium chloride will stop his heart.
Nighttime on (and off) the Pocono slopes has own special appeal 16 Jan 2006
Newsday, ...plunge. Although Camelback's high-pressure sodium lights provide more than enough light to ski, nothing can substitute for the sun. ...
Crowflight Files NI 43-101 Technical Report And Resource Estimate ... 16 Jan 2006
CCNMatthews (press release), Vancouver. Fire assays were performed on all the samples for Gold and PGE's which undergo an ICP-AES finish and Sodium Peroxide Fusion. ...
Light and Easy Lemon Chicken 16 Jan 2006
Arizona Republic, Each serving contains approximately: 247 calories; 8 g fat; 104 mg cholesterol; 149 mg sodium; 4 g carbohydrates; 41 g protein; negligible fiber.
For Women: Friends and pets are Good for the Heart 16 Jan 2006
Saturday Evening Post, Avoid salt. Read food labels carefully and check your medicine cabinet--Alka-Seltzer, Aleve, and most antacids contain forms of sodium. ...
The Amazing Heart 16 Jan 2006
Saturday Evening Post, ...right). The electrical impulse is due to the flow of ions, mainly sodium, potassium, and calcium, in and out of the cells. This ...
Recipe: Shortbread cookies 16 Jan 2006
The Grand Rapids Press, ...per each 1-inch square: 22 calories, 0 grams protein, 1 gram fat, 3 grams carbohydrate, 0 grams fiber, 2 milligrams cholesterol, 12 milligrams sodium.
Desktop diners should keep food safety in mind 16 Jan 2006
Toledo Blade, Dash. The 2005 USDA Dietary Guidelines urged Americans to decrease sodium consumption to no more than 2,300 mg per day. Currently ...
Genelabs suffers setback on lupus drug 16 Jan 2006
Pharma Times (subscription), And earlier in 2005, La Jolla Pharmaceuticals had to shed staff after failing to win approval fort Riquent (abetimus sodium), a treatment for lupus kidney ...
Fastlane: Recipes for busy cooks 16 Jan 2006
The Courier-Journal, ...its parts. The secret to its flavor boost: reducing a lot of low-sodium chicken broth to a highly flavorful one-half cup. You could ...
Recipe: White chocolate cranberry cheesecake 16 Jan 2006
The Grand Rapids Press, Nutrition information: 411 calories, 7 grams protein, 29 grams fat, 30 grams carbohydrate, 0 grams fiber, 126 milligrams cholesterol, 302 milligrams sodium. ...
GMT: Monday, Jan. 16 16 Jan 2006
WFAA (subscription), It makes no sense! Choose either lotion-based cleansers or gel cleansers that avoid the harsh ingredient, Sodium Laureth Sulfate. ...
Oatmeal Pancakes 16 Jan 2006
Kansas City infoZine, Per pancake: 78 calories, 1 g. total fat (less than 1 g. saturated fat), 13 g. carbohydrate, 4 g. protein, 1 g. dietary fiber, 157 mg. sodium.
Mobilian to be executed for killing Pensacola police officer 16 Jan 2006
Mobile Register, The AP said a study published last year in The Lancet medical journal indicates the pain killer, sodium pentathol, wears off before the inmates die.
Lamb chops teriyaki 16 Jan 2006
Munster Times, Nutrition information per serving: 390 cal., 8 g total fat (3 g saturated), 90 mg chol., 615 mg sodium, 52 g carbo., 6 g dietary fiber, 27 g pro.
DRAXIS Receives FDA Approval for Diagnostic Iodine I-131 Capsules Jan 13, 2006
CNW Telbec (Communiqués de presse), DAX) (NASDAQ: DRAX) has received approval from the US Food and Drug Administration (FDA) regarding its supplemental new drug application for Sodium Iodide I ...
Patrol Identifies Victim In Tanker Crash Jan 13, 2006
Yankton Daily Press, Highway Patrol on Friday released the name of a Washington state man who was killed when his pickup truck collided with a tanker carrying liquid sodium cyanide ...
20% Patients On Commonly Prescribed Diuretics Have Abnormal Sodium ... Jan 12, 2006
Medical News Today (press release), One in five patients taking diuretics commonly prescribed for high blood pressure or heart conditions end up with reduced sodium and potassium levels ...
Teva Announces Tentative Approval of Divalproex Sodium Delayed ... Jan 12, 2006
Genetic Engineering News, TEVA) announced today that the US Food and Drug Administration has granted tentative approval for the Company's ANDA for Divalproex Sodium Delayed-Release ...
First-Time Generic Approvals: Phenergan Tablets, Floxin Otic ... Jan 4, 2006
Medscape (subscription) ...ofloxacin 0.3% otic solution for the treatment of certain ear infections caused by designated strains of susceptible microorganisms; and sodium bicarbonate 7.5 ...
Company Says FDA OKs Sodium Level Drug Dec 30, 2005
Los Angeles Times, WASHINGTON -- The FDA has approved an intravenous drug for hospital patients suffering from potentially life-threateningly low sodium levels, the drug's ...
Sodium Intake Far Too High for Americans Dec 19, 2005
Newswise (press release) Newswise — Despite counseling by physicians, Americans still consume far too much sodium, putting them at risk for high blood pressure, heart disease and ...
Gold Miners and Sodium Cyanide Dec 27, 2005
Kommersant, ...“This mining company, a consumer and importer of sodium cyanide, believes that there are no grounds ... Korund is the sole Russian producer of sodium cyanides. ...
Too much sodium ingested in US Dec 20, 2005
United Press International ATLANTA, Dec. 20 (UPI) -- A study finds that sodium intake is far too high in the United States, and counseling by doctors appears to make little difference. ...
Company Gets FDA Approval for Drugs to Treat Low-Sodium Dec 30, 2005
All Headline News Inc. said Friday that the FDA has approved a new drug for hospital patients suffering from life-threatening low sodium levels. The ...
Company Says FDA Has OK'd its Sodium Treatment Drug Dec 31, 2005
HealthCentral.com US Food and Drug Administration has approved an intravenous drug for hospital patients suffering from potentially fatal depressed levels of sodium, the drug's ...
Company says FDA approves drug to treat low sodium levels in ... Dec 30, 2005
WTVM, A pharmaceutical company says the government has approved its drug for hospital patients suffering from potentially life-threatening low sodium levels. ...
Many diuretics users lack key minerals Jan 13, 2006
Monsters and Critics.com, But diuretics can also cause potentially severe health problems in some people by stripping the body of sodium and potassium, according to a new study in the ...
Too Much Sodium! Dec 25, 2005
Ivanhoe, ...(Ivanhoe Newswire) -- A new study reveals Americans consume far too much sodium, even if they already have high blood pressure and despite getting advice from ...
Synthetic Sodium Transporter Dec 28, 2005
Chemical & Engineering News Researchers have taken a step closer to a new type of synthetic ion channel with a G-quadruplex that acts as a sodium transporter (J. Am. Chem. Soc. ...
DRAXIS Receives FDA Approval for Diagnostic Iodine I-131 Capsules Jan 13, 2006
PharmaLive.com (press release), ...has received approval from the US Food and Drug Administration (FDA) regarding its supplemental new drug application for Sodium Iodide I-131 Capsules USP ...
Making Lemonade Out of Real Lemons Ross E. Getman Jan 14, 2006
Opinion Editorials, There is speculation that the benzene traces originated from the sodium benzoate by way of photolytic degradation. Koala Springs ...
Draxis Health receives FDA approval for diagnostic iodine capsules Jan 13, 2006
Calgary Sun, The drug developer said Friday the FDA approved the application for oral Sodium Iodide I-131 Capsules USP, used to perform the radioactive iodide uptake tests ...
Keeping a stealth killer at bay Jan 13, 2006
Frontiersman (subscription), People with hypertension can help keep their blood pressure levels by adhering to a diet low in sodium (which causes fluid retention and thereby boosts blood ...
One in five patients on commonly prescribed diuretics have ... Jan 11, 2006
I-Newswire.com (press release) 21 per cent of patients on commonly prescribed diuretics for blood pressure and heart problems end up with lowered sodium and potassium levels, which can lead ...
One in Five Patients on Commonly Prescribed Diuretics Have ... Jan 11, 2006
DG News 11, 2006 -- One in five patients taking diuretics commonly prescribed for high blood pressure or heart conditions end up with reduced sodium and potassium ...
US court approves Wyeth-Teva settlement on Effexor Jan 15, 2006
Globes, Teva has also announced tentative FDA approval for its Divalproex Sodium Delayed-Release Tablets USP, 125 mg, 250 mg and 500 mg. ...
Company Gets Approval From FDA To Sell Low-Sodium Treatment Jan 2, 2006
All Headline News Inc. says Friday that the FDA has approved a new drug for hospital patients suffering from life-threatening low sodium levels. The ...
Marlyn Monette: Louisiana sports-themed cookbook a winner Jan 11, 2006
Shreveport Times, Approximate values per serving: 349 calories, 25 g fat, 105 mg cholesterol, 9 g protein, 21 g carbohydrate, 1 g fiber, 350 mg sodium. ...
Company Says FDA OKs Sodium Level Drug Dec 30, 2005
MSN Money WASHINGTON (AP) - The FDA has approved an intravenous drug for hospital patients suffering from potentially life-threateningly low sodium levels, the drug's ...
Company Says FDA OKs Sodium Level Drug Dec 30, 2005
ABC News WASHINGTON Dec 30, 2005 — The FDA has approved an intravenous drug for hospital patients suffering from potentially life-threateningly low sodium levels, the ...
Americans Consume Far Too Much Salt and Sodium Dec 20, 2005
MedIndia, Americans consume far too much sodium, putting them at risk for high blood pressure, heart disease and stroke, according to a new study published in the ...
Three steps to better health Jan 14, 2006
Scotsman, Sodium is the component in salt that gives cause for concern, as it contributes to high blood pressure, heart disease and strokes. ...
Diuretics may decrease electrolytes level Jan 14, 2006
MedIndia, Thiazide diuretics which are prescribed for preventing strokes have been found to reduce electrolytes sodium and potassium which may cause low blood pressure ...
DRAXIS Receives FDA Approval for Diagnostic Iodine I-131 Capsules Jan 13, 2006
Yahoo! News (press release) NASDAQ: DRAX - News) has received approval from the US Food and Drug Administration (FDA) regarding its supplemental new drug application for Sodium Iodide I ...
Meals on Wheels seeks volunteers Jan 13, 2006
Johnson County Sun, ...clients. * Lowered sodium - 800 milligrams or less of sodium per day. No high sources of sodium such as ham or sausage. * Carbohydrate ...
Buying Meat: Are You Getting What You Pay For? Jan 13, 2006
CBS4Boston, All types of cuts are now enhanced with a mixture of water, salt and sodium phosphate. ... Another concern is the high level of sodium in this solution. ...
Laser Vision Lets Astronomers See Clearer, Fainter Jan 13, 2006
Newswise (press release) Newswise — A new sodium laser is giving 50 times more sky coverage to the atmospheric-correcting technology known as adaptive optics on the Keck II telescope ...
Fears raised over diuretic drugs Jan 11, 2006
Health Sentinel Doctors are being urged to monitor people to whom they prescribe diuretics after a study linked the drugs to low sodium and potassium levels. ...
Foods that once were bad are now good Jan 9, 2006
Newsday, Now, it has turned out that sodium nitrate in preserved meats may help preserve the people who eat it, that ice cream improves your mood, that popcorn counts ...
Try pork: It's fast-cooking comfort food Jan 10, 2006
Richmond Times Dispatch, ...unseasoned grill and oven-ready pork tenderloins that are, according to one label, "enhanced with up to 10 percent of a solution of water, sodium lactate, salt ...
INTERTRIGO COMES FROM SKIN RUBBING AGAINST SKIN Jan 4, 2006
Charlotte Sun-Herald, Also, is it safe to drink water to which sodium has been added? ... The sodium question depends on how much sodium the water softener adds to the water. ...
Health Stocks in Motion Jan 13, 2006
TheStreet.com Shares of Draxis Health (DRAX:Nasdaq - commentary - research - Cramer's Take) rose 2% after the company's new drug application for diagnostic sodium iodide I ...
Internal Soda Co Docs On Benzene Formation Uploaded Ross E. Getman Jan 8, 2006
Opinion Editorials, ..."1. Second Trumbull Experiment (all combinations of Sodium Benzoate, Citric Acid, Ascorbic Acid and Yellow #6). Results attached. ...
Wyo. crash spills toxic chemical Jan 13, 2006
Rapid City Journal, CASPER, Wyo. (AP) - A crash involving a pickup truck and a tanker truck carrying toxic liquid sodium cyanide killed ... Sodium cyanide can be fatal if ingested. ...
Regional News Briefs Jan 13, 2006
Milwaukee Journal Sentinel (subscription), ...old girl at his Mequon home in 2001 and 2002; tried to persuade a 20-year-old woman last September to touch her tongue with a tablet of sodium hydroxide, an ...
Group To Investigate Fatal Wastewater Plant Explosion Jan 14, 2006
Local6.com, Plant when employees who were working to repair a metal roof damaged by last year's hurricanes, used a cutting torch near methanol and sodium sulfate tanks. ...
Weekly calendar Jan 14, 2006
Durham Herald Sun, Will discuss and sign, "The Rice Diet Solution: The World-Famous Low-Sodium, Good-Carb, Detox Diet for Quick and Lasting Weight Loss." Thursday, 7 pm. ...
Rick Steelhammer Jan 14, 2006
Charleston Gazette (subscription), ...vogue. This time, the trend favored thick glasses, receding hairlines, relaxed-fit Dockers, and high-sodium salt-and-pepper hair. ...
Baking soda has its purposes, but no substitute Jan 15, 2006
Scripps Howard News Service, Baking soda, also known as sodium bicarbonate, has a number of functions in baking: it acts as a leavener as well as a browning agent. What does that mean? ...
Lantibio, Inc. and TRB Chemedica Announce Agreement for US ... Jan 12, 2006
CNW Telbec (Communiqués de presse), ...supply/manufacturing agreement for the US development and marketing of VISMED(R). VISMED(R) is a patented formulation containing sodium hyaluronate, currently ...
Ridge Crest Cleaning Limited launch UK's first "green" cleaning ... Jan 15, 2006
PR Leap (press release), ...brighteners, chlorine bleaches, petroleum-based additives, formaldehyde, titanium di-oxide, chemical plasticizers, synthetic dyes, sodium tallowate, glycerin ...
Science casts mushrooms in healthful light Jan 15, 2006
Kentucky.com, These noodles contain no cholesterol, yet they have the same taste and texture as egg noodles; they also are low in fat and sodium. ...
A sparkling idea Jan 14, 2006
Louisville Courier-Journal, If you keep track of such things, a 240-milliliter serving contains 8 milligrams of sodium and 3 percent of daily recommended calcium. ...
Connie Aclin: Food safety important for moms-to-be Jan 13, 2006
Shreveport Times, Serve over rice. Approximate values per 1 cup serving: 274 calories, 8 g fat, 77 mg cholesterol, 30 g protein, 17 g carbohydrates, 187 mg sodium. ...
Rainwater capture can aid with gardening in dry times Jan 14, 2006
Lufkin Daily News, ...for a water softener. Rainwater is also ideal for those on low-sodium diets, since it contains no salt. Plants respond to rainwater ...
Health & Fitness News in Brief Jan 14, 2006
Bryan College Station Eagle, Herbs are a healthy substitute for salt if you are watching sodium intake. These will add low-calorie, low-sodium flavor to foods. ...
Newton works to shed light on situation Jan 15, 2006
Boston Globe, The city knew about the Walnut Road blackout and ordered high-pressure sodium lamps and other replacement parts on Nov. 21, Solomon said. ...
New sanitizing spray gentle Jan 14, 2006
Akron Beacon Journal, The product contains sodium hypochlorite, the same compound used in household bleach but in a much lower concentration that's more akin to pool water. ...
Secrets of the sea Body care Follow-up Healing touch Jan 15, 2006
Calcutta Telegraph, ...sea level contains essential minerals like potassium that regulates osmosis and water balance, magnesium that affects cell metabolism, sodium that influences ...
Pet Ecology Brands, Inc. Announces Gross Revenue and Earnings ... Jan 11, 2006
Market Wire (press release) ...launching its fat free cat treats and vitamin enhanced dog treats by the end of March, and also a line of reduced fat and sodium microwavable gourmet cat ...
Salt is salt, despite the type Jan 11, 2006
The Grand Rapids Press, According to the "Food Lover's Companion" by Sharon Tyler Herbst, all salt (sodium chloride) comes either from salt mines or from the sea. ...
Health Alert: Food labels Jan 9, 2006
WIS, ..."I always read the labels because I don't want too much sodium. That's the first thing I look for.". ... And sodium caseinate is a milk protein. ...
Hot and spicy in the freezer Jan 12, 2006
Miami Herald, Green Guru's (10 ounces, $3.39) has an acceptable 339 calories and 5 grams of fiber, but 820 milligrams sodium and 18 fat grams. ...
Get with the pan Jan 11, 2006
Shreveport Times, Approximate values per serving: 803 calories, 40 g fat, 212 mg cholesterol, 33 g protein, 77 g carbohydrate, 4 g fiber, 943 mg sodium. ...
Goodbye Cyanide, Hello Mystery Process Jan 11, 2006
Boise Weekly, Desert Mineral CEO Dan Terzo told BW his company has long had plans to use sodium bromide rather than cyanide but only recently decided to change course. ...
Make It for Dinner: Chicken rollatini with salamai and roasted ... Jan 12, 2006
Kansas City Star, Per serving: Calories: 356; Protein: 59.21g; Fat: 12.29g; Carbohydrates: 1.04g; Sodium: 743mg; Saturated fat: 3.31g; Monounsaturated fat: 4.74g ...
Noodle-less Veggie Lasagna Jan 10, 2006
9NEWS.com, ...cutting. Per Serving: 356 Calories; 14g Fat; 33g Protein; 25g Carbohydrate; 5g Dietary Fiber; 80mg Cholesterol; 673mg Sodium. for ...
220 closed at 10 am Jan 15, 2006
The Casper Star Tribune, 10 miles west of Casper at mile marker 104, would be closed at approximately 10 am for about four hours while a load of liquified sodium cyanide from a wrecked ...
School hostel food scare Jan 5, 2006
Namibian, Namibian warned that the meat products such as mince and sausage supplied to most of Namibia's hostels contained dangerously high levels of sodium (salt) that ...
Injections at SRNH found contaminated Jan 12, 2006
Hindustan Times, ...recently. Three 2 ml viols of dexamethasone sodium phosphate injection have been found containing fungus and dust particles. The ...
Antibiotic Growth Promoters on Their Way Out Jan 12, 2006
PR Newswire (press release), The last four antibiotics currently being used as growth promoters - flavophospholipol, monensin sodium, salinomycin sodium and avilamycin - will be completely ...
Rt. 220 closed near Casper following deadly crash Jan 12, 2006
Billings Gazette, CASPER -- A crash involving a pickup truck and a tanker truck carrying toxic liquid sodium cyanide killed one person and closed Wyoming 220 south of here. ...
Knight Ridder Newspapers Jan 11, 2006
Bismarck Tribune, Serve hot. Per serving: 29 calories, 2g protein, 2g fat (1g saturated), 1g carbohydrate, 26mg sodium, 6mg cholesterol, 0g dietary fiber. ...
PR Pharmaceuticals (PRP) Announces Collaboration With OSI ... Jan 11, 2006
PR Newswire (press release), ...agreement with OSI Pharmaceuticals to collaborate on the development of a sustained release formulation of Macugen(R) (pegaptanib sodium injection), a novel ...
FDA Approves Astellas' Vaprisol® For Treatment Of Euvolemic ... Jan 1, 2006
Medical News Today (press release), ...indicated for the treatment of euvolemic hyponatremia, a potentially life-threatening condition that occurs when the body's blood sodium level falls ...
Ministry to investigate hostel food Jan 8, 2006
Namibian, ...on Friday exposed how the Catering Association of Namibia (CAN) and its seven member companies were using seaweed-derived products, namely sodium alginate and ...
The X-pert Files: James Watson Jan 3, 2006
New Zealand Herald, It outlines how farmers of the era raced to embrace sodium chlorate as a ragwort killer. Unfortunately, when mixed with the cotton ...
A" Means "One-and-Only-One Jan 5, 2006
Mondaq News Alerts, ...calcium source and at least one phosphoric acid source free of uncombined water as dry ingredients; and a solution consisting of water and a sodium phosphate ...
Watershed council focuses on winter's de-icers as chlorine source Jan 11, 2006
Gaylord Herald Times, Although sodium chloride is an inexpensive and effective choice, concerns are frequently raised about its potential negative impacts, particularly from chloride ...
ACE Inhibitors Slow Progression of Chronic Renal Disease Jan 11, 2006
MedPage Today, ...the recommended salt intake (documented by periodic 24-hour urine testing) is approximately 90 to 120 meq per day (approximately 2 to 3 g of sodium per day). ...
Soup is an easy and inexpensive meal Jan 11, 2006
Hagerstown Morning Herald, Soup is a tasty way to eat lots of healthy vegetables and beans and you can control the sodium and fat content. Watching your weight? Soups can help. ...
Label Lingo Jan 2, 2006
Winnipeg Free Press (subscription), Under the rules, labels must state the number of calories, the amount of total fat, saturated and trans fats, cholesterol, sodium, carbohydrate, fibre, sugars ...
Penwest Announces Results of Phase IIa Trial for PW2132 Dec 20, 2005
PR Newswire (press release), ...- Torsemide ER Indicates Better Sodium Excretion in Congestive Heart Failure Patients Than Immediate Release Product - DANBURY, Conn., Dec. ...
More monitoring needed for patients taking diuretics, study ... Jan 13, 2006
innovations report, They found that almost one in eight had received at least one prescription for thiazide diuretics between 1990 and 2002, but only 32 per cent had had their ...
Diuretics may decrease electrolytes level Jan 14, 2006
MedIndia, Thiazide diuretics which are prescribed for preventing strokes have been found to reduce electrolytes sodium and potassium which may cause low blood pressure ...
One In Five Patients On Commonly Prescribed Diuretics Have ... Jan 12, 2006
Science Daily (press release) They found that just under 12 per cent had received at least one prescription for thiazide diuretics between 1990 and 2002, but only 32 per cent had had their ...
One in Five Patients on Commonly Prescribed Diuretics Have ... Jan 11, 2006
DG News They found that just under 12% had received at least one prescription for thiazide diuretics between 1990 and 2002, but only 32% had had their sodium and ...
Fears raised over diuretic drugs Jan 11, 2006
Health Sentinel ...practices. They found around 12% of these had been given at least one prescription for thiazide diuretics between 1990 and 2002. ...
Many diuretics users lack key minerals Jan 13, 2006
Monsters and Critics.com, Of that sample, mostly adults in their 50s and 60s, nearly 4,000 had taken a thiazide diuretic between 1990 and 2002 to treat hypertension. ...
Beating trial rescheduled Jan 12, 2006
Fitchburg Sentinel, ...last spring. District Court Judge Elliott L. Zide rescheduled the trial for Claritza Castillo of 5 Holt St. because the alleged ...
TI in $3bn sensors arm sale to Bain Jan 9, 2006
MSNBC Steve Zide, managing mirector at Bain Capital, said: "We're enthusiastic about Sensors & Controls' future, and look forward to supporting the management team's ...
Bain Capital to acquire Sensors & Controls business of Texas ... Jan 10, 2006
AltAssets Steve Zide, a managing director at Bain Capital, said, 'Sensors & Controls is a market leader that enjoys long-standing customer relationships and is ...
Texas Instruments to Sell Sensors & Controls Unit for $3 Billion Jan 9, 2006
E-Commerce Times Steve Zide, a Managing Director at Bain Capital, said Sensors & Controls is a market leader that enjoys long-standing customer relationships and is ...
Crime should have been treated more seriously Jan 13, 2006
Fitchburg Sentinel, District Court Judge Elliott L. Zide sentenced firefighter Valentine Ramos, 36, of 414 Rollstone Road to a year of probation on Thursday after the trial, and ...
Man charged 16 years after alleged rape Dec 17, 2005
Fitchburg Sentinel, District Court Judge Elliott L. Zide let Houston leave the court on personal recognizance, as long as he returns when he is due back. ...
Texas Instruments sells unit to Bain for $3 bln Jan 9, 2006
Reuters ...that has leading market share in some pretty attractive industries and lots of opportunities to continue that growth," Bain Managing Director Steve Zide said. ...
Texas Instruments to Sell Unit to Bain for $3 Billion (Update6) ... Jan 9, 2006
Bloomberg ...are some big players, but Texas Instruments' sensors and controls business has carved out some strong competitive positions,'' said Steve Zide, a managing ...
Texas Instruments Is Selling Its Sensors Unit for $3 Billion Jan 9, 2006
New York Times, A managing director at Bain, Stephen M. Zide, said, "There is a considerable amount of value that can be unlocked by focusing solely on growing sensors and ...
Bain Capital to Purchase Sensors & Controls Business of Texas ... Jan 9, 2006
PR Newswire (press release), ...relationships and is geographically diversified with greater than 50 percent of its sales generated outside North America," said Steve Zide, a Managing ...
Bain to Purchase TI Sensors & Controls Business Jan 9, 2006
Test & Measurement World Online webzine, ...relationships and is geographically diversified with greater than 50 percent of its sales generated outside North America,� said Steve Zide, a managing ...
TI Sells Sensors & Controls Business Jan 9, 2006
RFID Journal Steve Zide, a managing director at Bain Capital, said in a statement that Sensors & Controls' long history, strong customer relationships and geographically ...
Fireman found guilty of assault on girlfriend Jan 11, 2006
Fitchburg Sentinel, District Court Judge Elliott L. Zide sentenced Ramos to a year of probation on Thursday after the trial, and ordered him to pay $718 in court costs, as well as ...
Mozilla Seeks Filmmakers For Ad Contest Dec 22, 2005
InformationWeek, Judges include Freddy Rodriguez, actor for the HBO show "Six Feet Under;" Ben Younger, writer/director of the movie "Boiler Room;" Warren Zide, producer of the ...
Texas Instruments sells unit to Bain for $3 bln Jan 9, 2006
Reuters ...them. This business will now be solely focused on strengthening its competitive position," said Bain Managing Director Steve Zide. ...
Training & Business Development: Do You Have A Mentor? Jan 3, 2006
RisMedia.com, Says iSucceed Mentor Nelson Zide of Framingham, Massachusetts, “the power of a mentor group comes from the fact you have other like-minded business people ...
New judge takes the bench Jan 6, 2006
Marietta Times, In all, Welch laid off nine court employees, including former clerk Roseanne Buell, court administrator Annette Zide and probation department head Joe Perry. ...
Junior high basketball Jan 5, 2006
Marietta Times, Ellwnwood 7, Daniel Canaday 4. Marietta scoring: Jake Zide 2, Tyler Davis 11, Adam Arnold 12, Lance Weppler 3, Brian Hendricks 2.
Firefox Calls "Action" on Ad Contest Dec 22, 2005
ClickZ News, Charlie's Angels and The OC director/producer McG; Partners director Geo Santini; Prime director/writer Ben Younger; and American Pie producer Warren Zide. ...
Firefox to take centre stage Dec 23, 2005
ZDNet UK, ...on Six Feet Under; McG, the director and producer of Charlie's Angels; Freddy Rodriguez, an actor in Six Feet Under; and Warren Zide, a producer on American ... | |
