Chlorhexidine resources


DRUG INFO
Chlorhexidine

Drug Name: Chlorhexidine

Indication: For reduction of pocket depth in patients with adult periodontitis, used as an adjunct to scaling and root planing procedures; For prevention of dental caries, oropharyngeal decontamination in critically ill patients; hand hygiene in health-care personnel; general skin cleanser; and catheter site preparation and care.



Pharmacology: Chlorhexidine, a topical antimicrobial agent, is used orally to treat mucositis, mouth infections, denture stomatitis, ulcerative stomatitis, acute necrotizing ulcerative gingivitis (ANUG), gingivitis, periodontitis and topically as an antiseptic and disinfectant.

Mechanism Of Action: Chlorhexidine's antimicrobial effects are associated with the attractions between chlorhexidine (cation) and negatively charged bacterial cells. After chlorhexidine is absorpted onto the organism's cell wall, it disrupts the integrity of the cell membrane and causes the leakage of intracellular components of the organisms.

Drug Category: Anti-bacterial Agents; Anti-Infectives; ATC:A01AB03; ATC:B05CA02; ATC:D08AC02; ATC:D09AA12; ATC:R02AA05; ATC:S01AX09; ATC:S02AA09; ATC:S03AA04

Brand Names/Synonyms: Bioscrub; Brian Care; C6143; CHEMBANK1360; CHLORHEXIDINE BAS; Chlorhexidin; Chlorhexidin [Czech]; Chlorhexidine; Chlorhexidine Base; Chlorhexidine Gluconate; Chlorhexidine, Free Base; Chlorhexidinum [Inn-Latin]; Cida-Stat; Cloresidina [Dcit]; Clorhexidina [Inn-Spanish]; Decanoylacetaldehyde Sodium Sulfide; Dyna-Hex; E-Z Scrub; Exidine; Fimeil; HSDB 7196; Hexadol; Hibiclens; Hibidil; Hibiscrub; Hibisol; Hibispray; Hibistat; Hibitane; Microderm; Nolvasan; Oro-Clense; Peridex; Periochip; Periogard; Pharmaseal Scrub Care; Prevacare R; Rotersept; Savloclens; Savlon Babycare; Sodium Houttuyfonamide; Soretol; Steri-Stat; Sterido; Sterilon; Superspray; Tubulicid

Dosage Forms: Oral rince; Pellet, extended- release; PerioChip (in a biodegradable matrix of hydrolyzed gelatin [cross-linked with glutaraldehyde]) (glycerin) (purified water); CREAM; DRESSING; GEL; LOTION; OINTMEN; SPONGE

Absorption: absorption of chlorhexidine from the gastrointestinal tract is very poor

Interactions: DrugBank: Interactions for Chlorhexidine

Interactions for Chlorhexidine:


No information provided.





Chemical IUPAC Name: 1-[amino-[6-[amino-[amino-(4-chlorophenyl)amino-methylidene]amino-methylidene]aminohexylimino]methyl]imino-N-(4-chlorophenyl)-methanediamine

Chemical Formula: C22H30Cl2N10

Half Life: Not Available

Drug Type: Approved Drug

# Accession No: APRD00545

CAS Registry Number: 55-56-1



Chlorhexidine News
(When available)



Attention Business, Health And Retailing Editors:  Jan 19, 2006
...of London's Queen Mary School of Medicine, Shows Skinvisible's Patent-Pending Chlorhexidine Hand Sanitizer is More Than 99 Percent Effective at Killing The ... - Canada NewsWire (press release),

Best Practices for 2006  Feb 1, 2006
...in the 2002 Centers for Disease Control and Prevention (CDC) Guideline for Hand Hygiene in Healthcare Settings are alcohols, chlorhexidine gluconate (CHG ... - Infection Control Today,

Arrow International, Inc. Introduces Maximal Barrier Precautions ...  Jan 11, 2006
ARROWg+ard antimicrobial catheter technology features a patented combination of silver sulfadiazine and chlorhexidine impregnated into the catheter surface. ... - Business Wire (press release),

Arrow International, Inc. Introduces Maximal Barrier Precautions ...  Jan 11, 2006
ARROWg+ard antimicrobial catheter technology features a patentedcombination of silver sulfadiazine and chlorhexidine impregnated intothe catheter surface. ... - Finanzen.net,

Tehnician charged in fatal injected with cleaning solution  Jan 31, 2006
At the conclusion, instead of being injected with a saline solution or radiological dye, she was mistakenly given chlorhexidine, a toxic antiseptic used to ... - Seattle Post Intelligencer

Skin Problems in Horses  Feb 1, 2006
...crusting. A mild bacterial skin infection can be treated topically by washing with an antiseptic like chlorhexidine (Nolvasan). ... - TheHorse.com,

(PRN) - Biffle Leads Wal-Mart FLW Tour Opener on Lake Okeechobee . ...  Jan 19, 2006
...of London's Queen Mary School of Medicine, Shows Skinvisible's Patent-Pending Chlorhexidine Hand Sanitizer is More Than 99 Percent Effective at Killi ... [+. ... - Bolsamania.com,

Summer Haircoat Tips  Jan 11, 2006
Antibacterial shampoos--which contain ingredients like iodine, chlorhexidine, and benzoil peroxide--can help prevent and correct skin problems. ... - TheHorse.com,

Reduction in Central Line–Associated Bloodstream Infections ...  Jan 20, 2006
...of targeted, evidence-based catheter insertion practices (ie, use of maximum sterile barrier precautions during insertion, use of chlorhexidine for skin ... - Journal of American Medical Association (subscription),

Hand sanitizer may help fight bird flu  Jan 24, 2006
..."We are seeking to broaden our marketing and distribution efforts in order to make our Chlorhexidine Hand Sanitizer available as soon as possible to the ... - CosmeticsDesign.com,

Zila Signs Agreement to Expand Distribution of Peridex(R) into ...  Jan 24, 2006
With a pleasant herbal mint taste, Peridex continues to work even after rinsing because one third of its active ingredient -- chlorhexidine gluconate -- binds ... - Business Wire (press release), Allergic Reactions  Jan 12, 2006
TheHorse.com, ...at home with Hodgkinson, Woody's treatments continued, with daily cold hosings of his legs, scrubbing the oozing and cracked skin with hibitane soap, picking ...

Indian men looking good  Jan 11, 2006
Asia Times Online, Similarly, for acne-scar reduction and "face-polishing" (removal of dead skin that cause patches), Kaya uses a microderm abrasion machine to spray very fine ...

Business briefs Jan. 6  Jan 6, 2006
Hilton Head Island Packet, ...esthetician. Services include facials, microderm-abrasion, chemical peels, waxing, body treatments and skin care products. Business ...

The artist and the aesthetician  Jan 5, 2006
St. Petersburg Times, ...and chandelier. Sheila will perform microderm abrasions, acid peels, Brazilian body wraps and bikini waxes and facials. Leah will ...

Fraxel Laser Allows Skin To Blend, Heal Easily  Dec 19, 2005
NBC 17.com, Kelly Jones had tried bleaching creams and microderm abrasion but still hadn't been able to get rid of brown spots on her face. ...

Doctor sues St. John's to open spa  Dec 13, 2005
News-Leader.com, He planned to hire staff to perform most of the spa treatments, which would include microderm facial peels and laser hair and spider vein removal. ...

Zila Nutraceuticals Establishes Scientific Advisory Board; Leading ...  Jan 11, 2006
Genetic Engineering News, ...marketer of products to promote oral health and prevent oral disease, including ViziLite(R) Plus oral examination kits and Peridex(R) prescription periodontal ...


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