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Cefadroxil
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DRUG INFO
Cefadroxil
Drug Name:
Cefadroxil
Indication: For the treatment of the following infections (skin, UTI, ENT) caused by; S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A beta-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staphylococci and Staphylococcu
Pharmacology: Cefadroxil, a first-generation cephalosporin antibiotic, is used to treat urinary tract infections, skin and skin structure infections, pharyngitis, and tonsillitis.
Mechanism Of Action: Like all beta-lactam antibiotics, cefadroxil binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cefadroxil interferes with an autolysin inhibitor.
Drug Category: Anti-bacterial Agents; Cephalosporins; ATC:J01DB05
Brand Names/Synonyms: Baxan; Bidocef; CDX; Cefa-Drops; Cefadroxil; Cefadroxil Micronised Powder; Cefadroxil Monohydrate; Cefamox; Ceforal; Cefradroxil; Cephos; Duracef; Duricef; Kefroxil; Oracefal; Sedral; Sumacef; Ultracef
Dosage Forms: Cefadroxil comes as a capsule, tablet, and liquid to take by mouth
Absorption: Cefadroxil is well absorbed on oral administration; food does not interfere with the absorption
Interactions:
DrugBank: Interactions for Cefadroxil
Interactions for Cefadroxil:
Drug/Laboratory Test Interactions
Positive direct Coombsí tests have been reported during treatment with the cephalosporin antibiotics. In
hematologic studies or in transfusion cross-matching procedures when anti-globulin tests are performed on the minor
side or in Coombsí testing of newborns whose mothers have received cephalosporin antibiotics before
parturition, it should be recognized that a positive Coombsí test may be due to the drug.
Chemical IUPAC Name: 8-[2-amino-2-(4-hydroxyphenyl)-acetyl]amino-4-methyl-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylicacid
Chemical Formula: C16H17N3O5S
Half Life: 1.5 h
Drug Type: Approved Drug
# Accession No: APRD00196
CAS Registry Number: 66592-87-8
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Cefadroxil News
(When available)
Can we always handle the truth? Jan 13, 2006
Washington Times, The technology is already being commercialized, as for example by No Lie MRI (www.noliemri.com) and Cephos (www.cephoscorp.com). ...
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