Botulinum toxin type B resources


DRUG INFO
Botulinum toxin type B

Drug Name: Botulinum toxin type B

Indication: For treatment of cervical dystonia, axillary hyperhidrosis, strabismus, facial wrinkles



Pharmacology: Myobloc inhibits acetylcholine release at the neuromuscular junction via a three stage process: 1) Heavy Chain mediated neurospecific binding of the toxin, 2) internalization of the toxin by receptor-mediated endocytosis, and 3) ATP and pH dependent translocation of the Light Chain to the neuronal cytosol where it acts as a zinc-dependent endoprotease cleaving polypeptides essential for neurotransmitter release.

Mechanism Of Action: Myobloc binds to and cleaves the synaptic Vesicle Associated Membrane Protein (VAMP, also known as synaptobrevin) which is a component of the protein complex responsible for docking and fusion of the synaptic vesicle to the presynaptic membrane, a necessary step to neurotransmitter release.

Drug Category: Antidystonic Agents; Anti-Wrinkle Agents; serums (80:04.00)

Brand Names/Synonyms: Botulinum neurotoxin type A precursor;BoNT/A;Bontoxilysin A;BOTOX[Contains: Botulinum neurotoxin A light- chain; Botulinum neurotoxin A heavy-chain]; Myobloc (Elan Corp; Solstice Neurosciences)

Dosage Forms: SOLUTION

Absorption: Not Available

Interactions: Not Available



Chemical IUPAC Name: Clostridium botulinum toxin type B

Chemical Formula: C6760H10447N1743O2010S32

Half Life: Not Available

Drug Type: Approved Drug

# Accession No: BIOD00070

CAS Registry Number: Not Available



Botulinum toxin type B News
(When available)


Study: Botox helps banish migraine pain  15 Jan 2006
Times of India, NEW DELHI: Botox, which helps reduce facial frown lines and wrinkles for up to 120 days, could prove to be a boon for a neurological disorder migraine. ...

Botox smooths over bladder problems for injured  15 Jan 2006
Australian, AUSTRALIA'S biggest trial of Botox -- a toxin most commonly associated with cosmetic surgery -- aims to put an end to the embarrassing bladder weakness ...

State officials consider sales tax on cosmetic surgery procedures  15 Jan 2006
Whittier Daily News, Taxing the silicone, the collagen, the Botox and other products that go into such procedures could inject millions of dollars into the state's coffers. ...

Plastic surgery a growing business  15 Jan 2006
Jamaica Observer, Botox injections, according to Arscott, are not very popular here. "The principal mode of action, using Botox, is to paralyse a ...

All American Gal: The Kimberly Baldwin Diary 2006  15 Jan 2006
Cyclingnews.com Well, the trading cards were delivered to our rooms the other day, and now I have 800 trading cards with a picture of me that screams for Botox. ...

Wrapping spring up in a bow  15 Jan 2006
Kansas City Star, On the show-business level, the goodies may be low- to high-end, from flip-flop sandals and designer handbags to Botox treatments. ...

Lori Sturdevant Columnist: The baby boom turns 60  15 Jan 2006
Minneapolis Star Tribune (subscription), Hively: But if they think they're going to ride their mountain bikes up Machu Picchu, and get the botox and plastic surgery and stay just the same as long as ...

Blinded by the white  15 Jan 2006
Pittsburgh Tribune-Review, Teeth whitening is now a $300 million per year industry, rooted in a national augmentation mania that includes Botox, hair transplants, laser eye surgery and ...

Essay Collections  15 Jan 2006
New York Newsday, But these essays, mercifully, rarely mention hair dye, Botox, hormone treatments or plastic surgery, although there is an account of an attempt to talk a ...

Botched Botox Reason For Jessica Simpson Black Eye  Jan 14, 2006
Post Chronicle ...who - for obvious reasons - wishes to remain anonymous, exclusively reveals to PerezHilton.com that Jess' eye drama could be a result of some botched Botox.". ...

Focus: Avon calling  Jan 14, 2006
The Sunday Times, The interest in Botox, chemical peels and reality-TV programmes on plastic surgery shows that people seem ever more concerned about how they look. ...

Brother, brother, if only we'd known  Jan 14, 2006
Belfast Telegraph, ...know that a few years later we would be unfazed by a Celebrity Big Brother contestant whose sturgeon lips were the result of, not collagen or Botox, but skin ...

'Supermodel' takes tart tongue, Botox looks to another show  Jan 12, 2006
Oxford Press, ...jobs. And people her age can do whatever they like. She herself is a regular Botox user and has had a facelift. Plastic surgery ...

Botox For Your Car?  Jan 13, 2006
WomanMotorist.com America's growing obsession with younger looking faces evidenced by the Botox craze, is inspiring car owners to prolong the appearance of their automobiles as ...

Medicis Eyes Botox-like Drug  Jan 10, 2006
Red Herring, ...maker Medicis Pharmaceutical said Tuesday it’s seeking a commercial partnership to market Reloxin, a potential competitor to blockbuster drug Botox, now that ...

'Housewives' desperately need to lay off the Botox  Dec 31, 2005
News-Leader.com, Only this game leaves one with nothing more than a flapping set of lips, no other features able to rip free from the paralyzing chains of Botox. ...

Allergan Launches BOTOX(R) Global Newsbureau Web Site  Jan 6, 2006
Drug Newswire (press release), ...announced today the launch of the BOTOX(R) Global Newsbureau -- www.BotoxGlobalNews.com -- a new interactive Web site designed to provide media worldwide with ...

Botox injections could improve women's sex lives  Jan 5, 2006
Hindustan Times, Women now have one more reason to get the skin firming Botox injections, after a new study has found that it is helps cure a sexual disorder called vaginismus. ...

Botox at the mall  Jan 3, 2006
Raw Story, Storefront medical spas, specializing in cosmetic procedures like botox and laser skin treatments, have grown from "a dozen or so" in the US five years ago to ...

Botox maker to buy rival Inamed  Dec 21, 2005
MSN Money IRVINE, Calif. (AP) - Botox maker Allergan has agreed to buy rival Inamed Corporation in a cash and stock deal valued at three-point-two (b) billion dollars. ...

No wrinkles? Botox maker's bid OK  Dec 15, 2005
CNN ...said Thursday that its board has unanimously approved Botox maker Allergan Inc.'s $3.2 billion offer in a deal that would allow Allergan to expand its wrinkle ...

Wives line up for botox injections or a fat lip  Dec 17, 2005
Sydney Morning Herald, BOTOX injections, facelifts and lip enlargements are proving popular gifts for Christmas as Sydneysiders shell out thousands of dollars on gift certificates to ...

MAINTAINING MOMMY  Jan 14, 2006
Globe and Mail, Laing, "Even a pared-down maintenance list is longer than it used to be when you consider that many women are also indulging in peels, Botox and injectable ...

Taxing battle over Botox  Dec 19, 2005
Sacramento Bee, In letters to the Sacramento-based board, Californians argued that medicines like Botox should never be taxed because such a move might open the door to taxes ...

Botox maker to buy rival Inamed  Dec 21, 2005
WKYC-TV, IRVINE, Calif. (Dow Jones/AP) -- Botox maker Allergan has agreed to buy rival Inamed Corporation in a cash and stock deal valued at $3.2 billion. ...

Making sense of botox  Dec 16, 2005
Nenagh Guardian, Botox is made in Ireland, in Co. Mayo, by a company called Allergan. ... Botox is a purified protein produced by the Clostridium botulinum bacterium. ...

Headache sufferer finally gets a shot of relief  Jan 12, 2006
Toronto Star, ...example.". After trying other treatments for several months, Finkelstein injected Hobday with Botox in April 2002. It worked. "This ...

SURGEON SAYS PETE IS £50K PLASTIC MAN  Jan 13, 2006
Mirror.co.uk, By Fiona Cummins Showbiz Reporter. Dead or Alive star Pete admits to four nose jobs, lip enlargement, Botox and "the odd glyceric acid peel". ...

Thread lifts: The new Botox?  Dec 13, 2005
MLive.com, By Jaye Beeler. Her dermatologist, Dr. Jack Dekkinga, suggested she look into ThreadLift, a quick, relatively bloodless procedure ...

Botox Has More Uses Than Just For Wrinkles, Reduces Pain And ...  Dec 13, 2005
Medical News Today (press release), While botulinum toxin A, or BTXA, is widely known for its use in dermatology and aesthetic medicine, a review article in the Journal of Cosmetic Dermatology ...

Innovations to create a more beautiful you in '06  Jan 11, 2006
Knoxville News Sentinel (subscription), Injectable innovations Injectable collagen was introduced more than 20 years ago, Botox was approved by the US Food and Drug Administration for cosmetic use in ...

Showgirl speak  Jan 13, 2006
Deccan Herald, ..."Look at my forehead she said, pointing to a perfectly smooth one framed with her brown mane. It was heavily lined and I got it fixed with Botox at Kaya. ...

When the urge to go is almost uncontrollable  Jan 13, 2006
Times Online, Recent studies have shown that Botox injections may help, too, in those patients for whom drug treatments don’t work or are not well tolerated. ...

MORT CRIM: Focus on benefits of aging  Jan 12, 2006
Detroit Free Press, And our fixation seems to be starting younger and younger. Some women in their 30s already are in line for Botox injections. And it's not just women anymore. ...

Wrinkle fillers could face off in '06  Jan 11, 2006
CNN/Money Restylane comes nowhere close to the blockbuster status of Botox, a facial injectable from Allergan (up $0.30 to $114.15, Research), based in Irvine, Calif ...

No sweat!  Jan 12, 2006
Times of India, If you thought botox was a remedy to merely ease fine lines and wrinkles on the faces, think again! Botulinus ... temperature. Enter botox.

Botox For More Than Ironing Wrinkles  Dec 13, 2005
Science Daily (press release) Botox Treatment For Wrinkles May Also Relieve Migraines (November 22, 2000) -- A treatment commonly used by dermatologists to get rid of facial wrinkles may ...

- By Our Correspondent  Jan 9, 2006
The Asian Age, New Delhi: The Escorts group in collaboration with Allergan India launched a book titled Botox: A Ready Reckoner on Sunday at the India International Centre ...

The latest wrinkle in Bay State beauty biz  Jan 9, 2006
Boston Herald, By Jessica Heslam. Gone are the days when a woman — or man — has to race around town to get Botox, laser hair removal, a facial and then a manicure. ...

Botox has more uses than just for wrinkles  Dec 13, 2005
Dominican Today, Washington.– While botulinum toxin A, or BTXA, is widely known for its use in dermatology and aesthetic medicine, a review article in the Journal of Cosmetic ...

Medical tourism to grow by 40 pc in India  Jan 8, 2006
Sify, Speaking after releasing a book on Botox, an anti-aging drug, she said the government was promoting India not only as a tourism destination but also as a ...

Cramer's 'Mad Money' Recap: Forever Young  Jan 10, 2006
TheStreet.com Cramer said it's superior to Botox in every way, which is why it's time to buy Restylane's maker Medicis Pharmaceutical (MRX:NYSE - commentary - research ...

Cosmetic tourism gets a face-lift  Jan 14, 2006
Times of India, India offers comparable service standards and pricing advantage.". The most sought-after services by foreigners are laser, botox and fillers. ...

THIS JUST IN ...  Jan 14, 2006
Toronto Star, ...cosmetic surgery's colossal shortcut — those now famous "injectables," better known by their much-hyped trademarks, the "expression freezing" Botox and the ...

Look as young as you feel with a lift  Jan 10, 2006
24 Hours Vancouver, ..."At 40-plus they prefer to try the less-invasive procedures such as Botox, FotoFacials, the Pan-G, ThreadLift and derma fillers for deep grooves," he says. ...

US: Youth-crazed society?  Jan 4, 2006
myDNA.com, The theory: Why wait until it might be too late? The antiwrinkle injectable Botox (Botulinum toxin) got popular in 2001, especially among middle-aged women. ...

Humphrey has found niche  Jan 14, 2006
Kentucky.com, Not even water.". Doctors twice injected botox into her esophagus area to relax the muscles, but it was a short-term solution. Eventually ...

Will Trinchi Boulevard wend its way into Broward County?  Jan 12, 2006
Boca Raton News, The story covered a new breed of spa popping up around the country touting Botox treatments, skin peels and laser procedures, along with the usual facials and ...

Circus stretches out with show  Jan 14, 2006
St. Albans Observer, ...world. Ours has the stretchiest skin in the world.". The botox-shy man was taken on by Haze and is now billed as Gary Stretch. Haze ...

A big generation starts to turn 60  Jan 14, 2006
Atlanta Journal Constitution (subscription), They fill gyms and jogging paths, and unabashedly buy Botox and Viagra. Millions also have morphed from liberals into conservatives. ...

Fighting Your Age: Doctors and Fitness Trainers Team up to Make ...  Jan 13, 2006
I-Newswire.com (press release) Comstock and Pai at Skin Spectrum routinely perform procedures such as laser surgery, leg vein treatment, laser resurfacing, Botox, and injectable fillers such ...

Truckee goes glam at Shampoo  Jan 14, 2006
Sierra Sun (subscription), ...for the dogs. Soon, she will even be hosting a Botox and cocktail party with a Beverly Hills plastic surgeon. "She always takes ...

Hydrotherapy is witnessing a renaissance of sorts  Jan 14, 2006
Economic Times, ...by this. Hydrotherapy is fast going the botox way as more and more people look to their hydrotherapist for an internal bath. You ...

Allergan extends offer for Inamed shares  Jan 9, 2006
BusinessWeek JAN. 9 6:15 PM ET Allergan Inc., maker of the Botox wrinkle treatment, on Monday said it extended its offer for shares of takeover target Inamed Corp. ...

Like a virgin  Jan 10, 2006
Daily Times, Forget Botox, liposuction or breast enlargement. The newest trend in plastic surgery for US women is vaginal reconstruction, including ...

Vaginal reconstruction sees new-found popularity among women in ...  Jan 10, 2006
TODAYonline, WASHINGTON — Forget Botox, liposuction or breast enlargement. The newest trend in plastic surgery for women in the United States ...

TURNER VOWS NEVER TO GET SURGERY  Jan 9, 2006
Contactmusic.com, THE ROSES actress, who famously bared all on a London stage as MRS ROBINSON in the hit play THE GRADUATE five years ago (01), has vowed never to get Botox or a ...

AGE no bar  Jan 5, 2006
Kolkata Newsline, The adage goes that you are as young as you feel and thanks to wonder treatments like botox, collagen and alpha-hydroxy-acids, looking ageless has never been ...

Saving face  Jan 11, 2006
WHDH-TV, Move over Botox. There's a new filler on the block and the results are getting rave reviews. Here are the details on how you can ...

Managing migraine with drugs, lifestyle changes  Jan 10, 2006
NorthJersey.com, Botulinum toxin Type A (Botox), in clinical trials for treatment of migraine, has shown promise. Other types of drugs can be valuable as well. ...

WHEN BALD ISN'T BEAUTIFUL  Jan 8, 2006
New York Post, By Elizabeth Hayt. January 9, 2006 -- From hair color to Botox injections, I zealously eradicate whatever part of me grows, grays and wrinkles against my will. ...

Boomers do not see themselves as old  Jan 10, 2006
Seniorscopie.com, The transformation of boomers into seniors may be terrific for the makers of Botox, but it threatens to rattle and perhaps even to wreak havoc with the economy ...

New Year; New You  Jan 5, 2006
Westside Today, This is definitely the Red-Carpet must have for that dewy, healthy glow.". Perhaps the most high profile quick fix on the scene is Botox. ...

<'Mystery' illness goes national NB resident featured on Discovery ...  Jan 8, 2006
North Bergen Reporter, ...start Stampe with simple injections, using a newly discovered drug at the time that is now a major part of cosmetic beautification throughout the world - Botox ...

Herol's gift of the jab  Jan 11, 2006
Sheffield Today, Graham. This week he had his bags lifted and his lines smoothed away after dropping his guard against incoming jabs - of botox! ...

Cosmetic-medicine offices move into malls  Jan 4, 2006
Pittsburgh Post Gazette, Most states require a doctor or licensed medical professional to oversee dermatology services -- including prescription injections like Botox or Restylane ...

Allergan Extends Offer for Inamed Shares  Jan 9, 2006
Schaeffers Research, Allergan Inc., maker of the Botox wrinkle treatment, on Monday said it extended its offer for shares of takeover target Inamed Corp. until Jan. 24. ...

Heartache of a headache  Jan 3, 2006
Contra Costa Times, They've also discovered that Botox prevents migraines in some people. ... A formal study on the use of Botox is expected to begin this month. ...

The beauty junkie trap  Jan 3, 2006
Scripps Howard News Service, ...million in 2004. The most popular, Botox injections, was performed on nearly 27 percent of those men and women. And surprisingly ...

‘Unshackled’ Medicis on the hunt  Jan 6, 2006
East Valley Tribune, Shacknai would not discuss the opportunities he is pursuing, but it was clear Thursday that snagging the rights to Reloxin, a Botox-like neurotoxin currently ...

Smoothing furrowed brow may be good for business  Jan 2, 2006
Toronto Star, ...brow makes customers sense anger or whose flat face causes others to sense sadness — both of which can hurt sales — he suggests a little botox between the ...

Health guru says no way to avoid aging  Jan 3, 2006
Everett Herald, If you're Dr. Andrew Weil, you calmly take stock of the facts, avoid anti-aging cures (you definitely don't do Botox) and pay more attention to your diet ...

DVD pirates successfully plunder Academy Award screeners.  Jan 13, 2006
Slate When Oscar season hits Hollywood, count on three things: teary-eyed speechifying, long lines at Botox boutiques, and tightened security on the "screeners ...

Attacking aging from every angle  Jan 4, 2006
Toronto Star, ...breakout.). A few years ago, I added another weapon to my anti-aging arsenal: fillers, such as Restylane, and the muscle-freezer Botox. ...

City's £7.5bn bonus bonanza  Jan 12, 2006
This is Money, ...cosmetic-surgery. The top three treatments are liposuction, nose jobs and injectable treatments such as Botox and collagen. Tammy ...

Online Casino Sponsors Lingerie Bowl III at Super Bowl - 01-13-06  Jan 12, 2006
Online Gambling Insider, Bodog.com Lingerie Bowl will be the biggest Super Bowl party in the world!" Amongst some of Rodman's more eccentric requests are botox injections available for ...

Day Spa Magazine’s Top Chain Spa of 2005, Gene Juarez is to be ...  Jan 10, 2006
PR Web (press release), With Botox® and baby-boomers on the rise, it is no shock to see Gene Juarez Spas offering HydroPeptide™ Intensive Concentrate Anti-Aging Crème as an ...

Spas team with MDs to heal inside and out  Jan 10, 2006
AZ Central.com, It says 471 US spas offered medical treatments in 2004, ranging from day spas that sell Botox shots to destination resorts offering diagnosis and treatment by ...

Taking aim at a proposed 'Botax'  Dec 20, 2005
Rocklin and Roseville Today, In letters to the Sacramento-based board, Californians argued that medicines like Botox should never be taxed because such a move might open the door to taxes ...

10 user(s) are online (1 user(s) are browsing News)  Jan 12, 2006
Theatreport.com, ...strength from God's legion of bodybuilders, the Power Team, a change in school policy at Hogwarts, an important message from Terry Schaivo, & a botox party for ...

Women are paying as much as $12,000 to redesign their genitalia  Jan 11, 2006
Dayton Daily News (subscription), These days, there's a plastic surgery procedure to renovate and rejuvenate just about anything. Botox for your wrinkles. Collagen for your lips. ...

Latest Carrey movie provides laughs  Jan 12, 2006
UNI Northern Iowan, When hourly wage jobs as a greeter at a superstore and a subject for Botox testers don’t work out, Dick and Jane decide robbery is the way to go. ...

Nightlife and more: Jan. 12 - Jan. 19  Jan 12, 2006
OC Weekly, Detroit derives the sound of young America redux: Brookline hits botox city USA, blushing like Pink Floyd and displaying many traits shared by former Detroit ...

Welcome to Hollywood  Jan 13, 2006
Australian, Of a Botox party in Los Angeles, he writes: "Four or five ageing women in sequence, all of them speaking of nothing but boutique sales in town and what certain ...

3 murder suspects escape  15 Jan 2006
Bradenton Herald, ...continued searching for them. The two still on the run were Johnny Earl Jones, 17, and Lamar Elan Benton, 19. Russell Sheriff Tommy ...

National Semiconductor Says China Sales Growth to Double to 20%  15 Jan 2006
Bloomberg The US chipmaker is targeting a rate higher than China's industry average of more than 10 percent for analog chips, Elan Lee, National Semiconductor's China ...

What's in store  15 Jan 2006
Detroit Free Press, Played with sharp, deadpan elan by Trenton native Mary Lynn Rajskub, Chloe has become the MVP of supporting players on "24." She even had a chance to grab a ...

Letterkenny's students show plenty of investment team spirit  15 Jan 2006
Unison.ie, The common thread between the leading entries in both sections is their choice of the top two best shares, Elan (up 78pc) and Marks & Spencer (45.5pc). ...

Test of fire for Bangalore City police  15 Jan 2006
Deccan Herald, Not for any spiritual gains, but to overcome fear and build confidence. The policemen from the Bangalore East Division performed it with elan. ...

'Star Spangled' show will return to Greensboro  15 Jan 2006
Greensboro News Record, The Allied drive into North Korea, started with such elan and expectations, had foundered when Chinese Communist Forces entered the war in huge numbers: In ...

Elan Announces Webcast of Fourth Quarter and Full Year 2005 ...  Jan 13, 2006
Genetic Engineering News, Elan Corporation, plc announced today that it will host a conference call on Tuesday, January 31, 2006 at 8:30 am Eastern Standard Time (EST), 1:30 pm ...

ELAN HOME SYSTEMS ANNOUNCES THP800C POINTABLE HOME THEATER ...  Jan 12, 2006
Home Toys (press release), LEXINGTON, KY -- ELAN Home Systems, a leading manufacturer of award-winning Multi-Room audio/video and home automation systems, announced today that the ...

Wife stops murdered doctor's cremation  Jan 14, 2006
Trinidad & Tobago Express, Sumatie Elan, the woman claiming to be the wife of murdered city doctor, Ravi Maharaj, has filed an injunction against his relatives preventing them from ...

Elan downgraded to "add"  Jan 13, 2006
New Ratings LONDON, January 13 (newratings.com) - Analyst Ian Hunter of Goodbody Stockbrokers downgrades Elan (ELN.NYS) from "buy" to "add." The target price is set to ...

MARKET COMMENT: Dublin Stocks End Flat, Elan +3.1%  Jan 12, 2006
New Ratings Elan +3.1% as investors await more news on the FDA's review of MS drug Tysabri. Financials mixed: Anglo Irish Bank -1.4%, Irish Life & Permanent +1.3%. ...

Senior Synchronized Skating Team Grabs First at the Mid-America ...  Jan 14, 2006
Miami Redhawks, ...second place Team Fusion. Team Elan of the Detroit Skating Club finished third followed by the University of Michigan. "I was very ...

My baby? It's a mixed basket of Ireland Inc  Jan 14, 2006
Irish Independent, However, I invested in only one company, Elan, to express that view. ... The whole sector did not collapse because Elan had company and product-specific problems. ...

Elan and EntreMed tie up technology deal  Jan 10, 2006
RTE.ie, Elan has entered into a license agreement in which EntreMed will use its nanocrystal technology to develop its oncology drug Panzem. ...

Elan and EntreMed agree NanoCrystal technology deal  Jan 11, 2006
In-PharmaTechnologist.com, 11/01/2006 - EntreMed have entered into a new agreement with Elan, which allows the clinical-stage pharmaceutical company to utilise Elan's NanoCrystal ...

Ex-Biogen counsel to pay $3m  Jan 13, 2006
Boston Globe, Ten days later, Biogen Idec and its partner, Elan Corp., made the stunning disclosure that they were suspending sales of Tysabri. ...

Elan, EntreMed Ink License Pact  Jan 10, 2006
TheStreet.com Elan (ELN:NYSE ADR - commentary - research - Cramer's Take) signed a license agreement granting EntreMed (ENMD:Nasdaq - commentary - research - Cramer's Take ...

Elan and EntreMed Execute License Agreement for Proprietary ...  Jan 10, 2006
PharmaLive.com (press release), DUBLIN, Ireland and ROCKVILLE, Md., January 10, 2006 /PRNewswire-FirstCall/ -- Elan Corporation, plc and EntreMed, Inc. today announced ...

ELAN AND ENTREMED EXECUTE LICENSE AGREEMENT  Jan 10, 2006
Small Times Jan. 10, 2006 - Elan Corp. plc (NYSE: ELN) and EntreMed Inc. ... Additionally, Elan will receive royalty payments based on sales of Panzem NCD. ...

Elan drives market advance  Jan 11, 2006
IrishExaminer.com, THE Irish market increased on the back of strong gains in Elan. The ISEQ Index finished up 19.20 points at 7494.37. AIB rose by ...

Elan Tysabri Could Hit $1.8B Sales - NCB  Jan 11, 2006
New Ratings ...negative sentiment." Maintains at buy. Elan +3.3% at EUR12.25. (QAF). Contact us in London. +44-20-7842-9464 Markettalk.eu@dowjones.com.

Accent Supplies Caliper Elan Overlay Tool to AMD Inc.  Jan 9, 2006
Business Wire (press release), ...leading supplier of lattice engineering and photolithography process control tools, today announced the successful deployment of its Caliper elan 300mm overlay ...

Roller-coaster ride for Elan shareholders on back of Tysabri  Jan 3, 2006
Biotechnology Ireland, Shareholders in Elan are getting used to a roller-coaster ride when it comes to the performance of the pharmaceutical company. The ...

Loving Elan's Latest Comeback  Jan 4, 2006
Forbes ...tracking and analysis service Marketocracy, recommends buying the American depositary receipts for shares of Irish biotechnology and drug delivery company Elan ...

Elan shares buoyed by hopes for Tysabri  Dec 16, 2005
Reuters DUBLIN (Reuters) - Shares in Irish drug maker Elan (ELN.I: Quote, Profile, Research) rose in Dublin on Friday, playing catch-up on a jump overnight in New York ...

ISEQ up as Elan continues recovery  Dec 16, 2005
Ireland Online, Pharmaceutical giant Elan continued its remarkable recovery today as the ISEQ index shot up 95.64 points to 7254.89 today to end the week on a high. ...

Elan, financials drag ISEQ down  Dec 19, 2005
Ireland Online, Insurer FBD was up €1.08 (3%) at €37.23. The group today issued a promising pre-close trading statement. The financials, however, had a poor day. ...

Michael Jahn Joins ELAN GMK  Dec 26, 2005
PR Web (press release), Simi Valley, CA. (PRWEB) December 26, 2005 -- ELAN GMK, the global authority on imaging, printing and digital document delivery solution, today announced the ...

Elan to Present at Healthcare Conferences in January 2006  Dec 22, 2005
Business Wire (press release), DUBLIN, Ireland--(BUSINESS WIRE)--Dec. 22, 2005--Elan Corporation, plc announces that it will present at two healthcare conferences in January 2006. ...

Elan to Present at Healthcare Conferences in January 2006  Dec 22, 2005
Finanzen.net, On January 5, 2006, Elan will present at the Morgan StanleyPharmaceutical CEO's Unplugged Conference in New York at 8:00 amEastern Standard Time (EST), 1:00pm ...

Elan shares surge 8pc on Dublin market  Dec 16, 2005
Unison.ie, SHARES in drugmaker Elan finished the day higher on the Irish market yesterday. Elan stock closed up over 8pc at €11.69. The shares ...

Elan "buy"  Dec 28, 2005
New Ratings LONDON, December 28 (newratings.com) - Analyst Ian Hunter of Goodbody Stockbrokers maintains his "buy" rating on Elan Corp Plc (DRX.FSE). ...

Elan share price may drift on a lack of news  Dec 29, 2005
Unison.ie, SHARES in Elan are set to fall back in January following a strong run in early December which saw the stock's value rise by 38pc in just 15 days, a leading ...

Elan Nutrition, Inc. Develops Award Winning Bar  Dec 29, 2005
NPIcenter (press release), Elan Nutrition, Inc., a leading developer and contract packer of nutrition bars based in Grand Rapids, Michigan, was recently honored with a CSP Retailer ...

Ryanair and Elan lead ISEQ recovery  Dec 21, 2005
Irish Examiner, THE ISEQ index recovered yesterday led by gains in Ryanair and Elan. At the closing bell, the Dublin Exchange had risen 49.51 points to 7226.79. ...

Elan Nutrition Receives NSF Certification  Dec 29, 2005
NPIcenter (press release), Elan Nutrition has received notification that the company’s facility in Grand Rapids , Michigan has passed the NSF GMP Certification for functional foods and ...

Merrill Lynch issues 'sell' rating on Elan  Dec 24, 2005
Unison.ie, IN a major new report on the biotech sector, international investment bank, Merrill Lynch, has recommended selling Elan shares as its top European sell idea ...

Elan "sell"  Dec 20, 2005
New Ratings NEW YORK, December 20 (newratings.com) – Analysts at Merrill Lynch reiterate their "sell" rating on Elan Corp (ELN.NYS). In a ...

Sharp fall in Elan as Merrill says 'sell'  Dec 20, 2005
Unison.ie, SHARES in Elan fell sharply yesterday after US investment house Merrill Lynch advised investors to sell the drug company's shares. ...

Elan Momentum Seen Easing Over Holidays  Dec 19, 2005
New Ratings 1229 GMT [Dow Jones] Elan -4.2% at EUR11.20 in profit-taking after a 30%-plus gain since the start of December, says Goodbody Stockbrokers' Ian Hunter. ...

Elan plunges 462 places on BusinessWeek's Global 1200 company ...  Dec 19, 2005
FinFacts Ireland, Some big companies such as Google are not part of this index. The magazine says: Pity the shareholders of Irish drugmaker Elan Corp., for example. ...

Elan Etap Moody Oyster and Shipman lead in Awards  Dec 16, 2005
Sail World, The Croatian Elan 434, ‘Unsinkable’ Etap46DS from the Netherlands, the British Moody 49 and Oyster 72 are the sailing boats over 40ft short-listed to take ...

Local artists’ work at Chateau Elan  Dec 15, 2005
The Citizen.com, The League of Fine Artists South (LOFAS) will exhibit in the gallery at The Winery -Chateau Élan in December. Five fine artists ...

Braselton plans visitors bureau to market town  Jan 12, 2006
Main Street Newspapers, Braselton already receives a five percent hotel/motel tax for room lodging from the town’s three hotels — The Inn at Chateau Elan, Holiday Inn Express at ...

Doctor beaten to death  Jan 12, 2006
Trinidad News, ...gun. Maharajh’s common-law-wife, Sumatie Elan, found him lying unconscious and face down on the floor at about 1 pm yesterday. ...

UPDATE 1-Ex-Biogen exec to pay $3 mln for insider trading  Jan 12, 2006
Reuters The case stems from Biogen's suspension last February of the multiple sclerosis drug Tysabri after the company along with development partner Elan Corp. ...

XM-R3™ TRIPLE SATELLITE AUDIO RECEIVER FROM ELAN® HOME SYSTEMS ...  Dec 12, 2005
Home Toys (press release), Lexington, KY-- ELAN® Home Systems, a leading manufacturer of award-winning Multi-Room audio/video and home control systems, announced today that the company ...

Elan Ships Triple XM Receiver  Dec 13, 2005
Designtechnica, Elan Home Systems, a manufacturer of multi-room audio/video and home automation systems, recently announced a new receiver component geared towards XM ...

UK's Stocks Decline, Paced by Shire, Vodafone; ISEQ Advances  Jan 13, 2006
Bloomberg The FTSE All-Share Index slid 0.6 percent to 2886.64. Ireland's ISEQ Overall Index rose 10.94, or 0.2 percent, to 7532.99, buoyed by Elan Corp. ...

Elan and EntreMed Execute License Agreement for Proprietary ...  Jan 9, 2006
TMCnet 10, 2006 -- Elan Corporation, plc (NYSE: ELN) and EntreMed, Inc. ... Additionally, Elan will receive royalty payments based on sales of Panzem(R) NCD. ...

Elan and EntreMed Execute License Agreement for Proprietary ...  Jan 9, 2006
PR Newswire (press release), DUBLIN, Ireland and ROCKVILLE, Md., Jan. 10 /PRNewswire-FirstCall/ -- Elan Corporation, plc (NYSE: ELN) and EntreMed, Inc. (Nasdaq ...

Elan and EntreMed Execute License Agreement for Proprietary ...  Jan 9, 2006
Finanzen.net, Elan Corporation, plc (NYSE: ELN) and EntreMed, Inc.(NASDAQ: ENMD) today announced that they have entered into a LicenseAgreement in which EntreMed has been ...

Amerin stock surges by 20pc on drug results  Jan 13, 2006
Unison.ie, AMERIN, the drug company chaired by former Elan finance director Tom Lynch, saw its shares rise 20pc in early trading on the Nasdaq last night. ...

IFG climbs 16pc on broker reports  Jan 13, 2006
Unison.ie, It was followed by drug manufacturer Elan which gained 13pc. Elan shares gained after an investor conference at its Tysabri research partner Biogen. ...

Back in hot seat with quiver full of gold-tipped arrows  Jan 14, 2006
Unison.ie, Thanks to a sharp recovery by Elan late in the year, George's stocks ended up just about in positive territory, with an average gain of 2.4 per cent. ...

Approval to restart Phase IIa trial in MS patients  Jan 12, 2006
Biotech Intelligence (press release), This trial was voluntarily halted by Antisense Therapeutics in March 2005 in light of safety issues associated with Biogen Idec and Elan Corporation's multiple ...

Manpower Inc. to Announce 4th Quarter and Full-Year 2005 Earnings ...  Jan 12, 2006
Finanzen.net, In addition to the Manpower brand, the company operates under the brand names of Right Management Consultants, Jefferson Wells and Elan. ...

Belleayre Shows Its Appreciation  Jan 12, 2006
OnTheSnow.com, Consumer demo days are Saturday and Sunday, with reps from Atomic, Blizzard, Elan and Dynastar on hand to hypnotize you with their latest gear. ...

Elan to Present at Healthcare Conferences in January 2006  Dec 22, 2005
PharmaLive.com (press release), DUBLIN, Ireland--(BUSINESS WIRE)--Dec 22, 2005 - Elan Corporation, plc announces that it will present at two healthcare conferences in January 2006. ...

Elan to Present at Healthcare Conferences in January 2006  Dec 22, 2005
Genetic Engineering News, On January 5, 2006, Elan will present at the Morgan Stanley Pharmaceutical CEO's Unplugged Conference in New York at 8:00 am Eastern Standard Time (EST), 1 ...

XM-R3 Triple Satellite Audio Receiver From ELAN Home Systems Now ...  Dec 14, 2005
eHomeUpgrade, ELAN® Home Systems, a leading manufacturer of award-winning Multi-Room audio/video and home control systems, announced today that the company has begun ...

UPDATE 1-Wyeth plans trials of 3 Alzheimer drugs in 2006  Jan 13, 2006
Reuters The two other Wyeth medicines already in human trials are being developed under a 50/50 partnership with Irish drugmaker Elan Corp. ...

Winemakers begin to take advantage of court ruling  Jan 12, 2006
Bothell Herald, For a small winery such as Elan, which makes about 1,000 cases a year, being able to ship is crucial, said owner Linda Elliott-Smith, who has had 15 cases of ...

Former National City, KeyCorp execs form new manager  Jan 11, 2006
Pensions & Investments, Giesen. Mr. Giesen will be joined by former National City colleagues Mitchell Krahe and Ori Elan. Mr ... Messrs. Giesen and Elan. The ...

News In Brief  Jan 11, 2006
Unison.ie, ELAN has entered into a licensing agreement in which EntreMed will use its nanocrystal technology to develop its oncology drug Panzem. ...

What's your winter wonderland?  Jan 10, 2006
ic Wales, The usual suspects of Snowdon, Gower and the Elan Valley featured strongly but it was Tenby that was declared the surprise winner in terms of votes cast. ...

Biogen: FDA to rule on Tysabri  Jan 10, 2006
MarketWatch Biogen and partner Elan Pharmaceuticals voluntarily pulled Tysabri from the market in February 2005 after three cases of PML were reported. ...

European Stocks Fall in Week; Stoxx 600 Snaps 11-Week Advance  Jan 14, 2006
Bloomberg Standard & Poor's raised its outlook on the company's debt to stable from negative on better earnings prospects. Elan Corp. surged 13 percent to 13.14 euros. ...

Volunteer Opportunities  Jan 13, 2006
Boston Globe, ...and Brockton. Please contact Elan Babchuck at 617-457-8669 or ebabchuck@jcrcboston.org. MATCH-UP Interfaith Volunteers Inc. needs ...

Injury time looms on Big Brother  Jan 14, 2006
Telegraph.co.uk, ...nightmares. No Englishman would have survived them, and I hope his dignity and elan continue to put us to shame for years to come.

Where does the other half live?  Jan 14, 2006
Unison.ie, ...addresses. Kelly Martin, the former Merrill Lynch investment banker who runs Elan, gives his address as 1040 Fifth Avenue, New York. ...

Top tournament in North Wales  Jan 14, 2006
Wrexham Evening Leader, Ruthin have four players with Sioned Roberts and Elan Iorwerth in the under 16s and Llyr Iorwerth and Sarah Delonger in the 18s. ...

Hate the old kitchen? Love the new one  Jan 14, 2006
DesMoinesRegister.com, Davis suggested the heavy, comfortable bar chairs from Elan Contemporary Furnishings in Omaha that surround the eating part of the kitchen island. ...

ISEQ breaches 7500 threshold  Jan 9, 2006
Ireland Online, AIB rose 4c to €18.49 and Bank of Ireland rose 1c to €13.83. Pharmaceutical company Elan also recorded heavy gains, finishing up 36c to €12.02. ...

ISEQ falls just short of 7500 mark  Jan 11, 2006
Ireland Online, The Dublin market closed up 71.41 points at 7494.37 as Elan led the charge, up 69c, almost 6%, to €12.55. It was a mostly positive day for the financials. ...

10.45am Markets Update  Jan 10, 2006
RTE.ie, Shares in Ryanair were down 11 cent to €7.98 after a broker downgrade, while Elan shares lost 12 cent to stand at €11.90 after it announced a new ...

Schaeffer's Top and Bottom Ranked Stocks (CEPH, ELN, HSY)  Jan 9, 2006
Schaeffers Research, ...trading opportunities. The stocks appearing on today's list of top and bottom ranked stocks are Cephalon, Elan, and Hershey. Not ...

Live at MacWorld: EVDO to Upgrade for MacBook Pro  Jan 11, 2006
Gizmodo.com, ...updated as news comes in. The EVDOinfo forum reports a USB 2.0 dongle sold by Elan Digital Systems. EVDOinfo’s ExpressCard page ...

New drugs use saliva to help relieve pain  Jan 10, 2006
Auburn Citizen, ...about. Recently, new drugs have been added to the market, exenatides (Byetta/Amylin Lilly) and ziconotides (Prialt/Elan). These ...

Irish stock exchange on course to be European favourite  Dec 31, 2005
The Sunday Times, The main laggards were: Elan, where concerns over Tysabri affected investor sentiment; Waterford Wedgwood, which was dogged by weak sales in America; and Iona ...

2005 Gave Nanotech Investors Plenty to Chew On  Jan 6, 2006
Motley Fool American Pharmaceutical's success was closely followed by an announcement that Roche had signed a deal with Elan (NYSE: ELN) to apply Elan's nanocrystal ...

Sharewatch: Desmond piles up the chips on Amarin’s march to ...  Dec 31, 2005
The Sunday Times, The drug development company spun out of Elan raised $26.4m (€22.3m) just days before Christmas to fund what it hopes will be the final phase of trials for ...

CES Day Two: Must-Haves For Homebodies  Jan 6, 2006
KLAS-TV, ...all into one system.". Elan's home systems aren't just for the rich and famous building a brand new custom home. "About 50-percent ...

UK Stocks Climb, Paced by Royal Bank of Scotland; P&O Surges  Jan 11, 2006
Bloomberg Ireland's ISEQ Overall Index gained 0.8 percent to 7481.25, buoyed by shares of Elan Corp. ... Shares of Elan increased 3.7 percent to 12.3 euros in Dublin. ...

Joshi, Dhruv in title clash  Jan 13, 2006
Rediff, In the semi-finals, Maharashtra's Joshi, potting with elan, displayed silken touch to wallop Rupesh Shah of Gujarat 1498-832, while promising Dhruv halted the ...

Brockton girls are doubles trouble  Jan 12, 2006
Boston Globe, Bay Independent: With 10 seconds left in regulation, junior Elan Ziff (15 points) made two free throws to give Gann (3-4) a 56-54 victory over BU Academy. ...


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