Abarelix resources

DRUG INFO
Abarelix

Drug Name: Abarelix


Indication: For palliative treatment of advanced prostate cancer



Pharmacology: Used in the palliative treatment of advanced prostate cancer. Abarelix is a luteinizing hormone agonist that results in suppression of testicular or follicular steroidogenesis.

Mechanism Of Action: Abarelix binds to the gonadotropin releasing hormone receptor and acts as a potent inhibitor of gonadotropin secretion.

Drug Category: Antineoplastic Agents; Anti-Testosterone Agents

Brand Names/Synonyms: Plenaxis; Plenaxis (Praecis Pharmaceuticals)

Dosage Forms: Not Available

Absorption: Not Available

Interactions: Not Available



Chemical IUPAC Name: acetyl-D-ß-naphthylalanyl- D-4-chlorophenylalanyl-D-3-pyridylalanyl-L-seryl-L- N-methyl-tyrosyl-D-asparagyl-L-leucyl-L-N(e )-isopropyl-lysyl-L-prolyl-D-alanyl-amide

Chemical Formula: C72h95O14N14Cl

Half Life: 13.2 +/- 3.2 days

Drug Type: Approved Drug

# Accession No: BIOD00051

CAS Registry Number: 183552-38-7