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Abarelix
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DRUG INFO Abarelix
Drug Name:
Abarelix
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Indication: For palliative treatment of advanced prostate cancer
Pharmacology: Used in the palliative treatment of advanced prostate cancer. Abarelix is a luteinizing hormone agonist that results in suppression of testicular or follicular steroidogenesis.
Mechanism Of Action: Abarelix binds to the gonadotropin releasing hormone receptor and acts as a potent inhibitor of gonadotropin secretion.
Drug Category: Antineoplastic Agents; Anti-Testosterone Agents
Brand Names/Synonyms: Plenaxis; Plenaxis (Praecis Pharmaceuticals)
Dosage Forms: Not Available
Absorption: Not Available
Interactions: Not Available
Chemical IUPAC Name: acetyl-D-ß-naphthylalanyl- D-4-chlorophenylalanyl-D-3-pyridylalanyl-L-seryl-L- N-methyl-tyrosyl-D-asparagyl-L-leucyl-L-N(e )-isopropyl-lysyl-L-prolyl-D-alanyl-amide
Chemical Formula: C72h95O14N14Cl
Half Life: 13.2 +/- 3.2 days
Drug Type: Approved Drug
# Accession No: BIOD00051
CAS Registry Number: 183552-38-7
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